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11 results on '"Laville S"'

1. Evaluation of the adequacy of drug prescriptions in patients with chronic kidney disease: results from the CKD-REIN cohort

Author

Laville, S. M., Metzger, M., Stengel, B., Jacquelinet, C., Combe, C., Fouque, Denis, Laville, M., Frimat, L., Ayav, C., Speyer, E., Robinson, B. M., Massy, Z. A., Liabeuf, S., Chronic Kidney Dis Renal, Epidemiol, Information Network, C. K. D. Rein Stud, Université de Picardie Jules Verne (UPJV), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse, Agence de la biomédecine [Saint-Denis la Plaine], Service de Néphrologie-Transplantation-Dialyse, CHU Bordeaux [Bordeaux]-Groupe hospitalier Pellegrin, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Service d'Epidémiologie et Evaluations Cliniques [CHRU Nancy] (Pôle S2R), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Réseau Lorrain de prise en charge de l’insuffisance rénale chronique : Réseau NEPHROLOR (Nephrolor), Service Néphrologie/Dialyse [AP-HP Ambroise-Paré], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Ambroise Paré [AP-HP], Centre de Recherche Clinique, CHU Amiens-Picardie, CKD REIN, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Néphrologie [Ambroise Paré], Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Ambroise Paré, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Service de Néphrologie Transplantation, Dialyse et Aphérèse [CHU Bordeaux], CHU Bordeaux [Bordeaux], INSERM U1026 (INSERM, U1026), Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Service de Néphrologie [CHRU Nancy], Centre d'investigation clinique - Epidémiologie clinique [Nancy] (CIC-EC), Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Arbor Research Collaborative for Health, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Laboratoire de Biométrie et Biologie Evolutive - UMR 5558 (LBBE), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), DIPI (DIPI), ENISE, Mécanismes physiologiques et conséquences des calcifications cardiovasculaires: rôle des remodelages cardiovasculaires et osseux, and Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
pharmacoepidemiology, adjustment, [SDV]Life Sciences [q-bio], cockcroft-gault, prescribing, urologic and male genital diseases, female genital diseases and pregnancy complications, information, medications, equations, residents, community, epidemiology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, guidelines, Pharmacology & Pharmacy, drug utilization, ComputingMilieux_MISCELLANEOUS, chronic kidney disease
Abstract

International audience; Aims Drug prescription is difficult to manage in patients with chronic kidney disease (CKD). We assessed the prevalence and determinants of inappropriate drug prescriptions (whether contraindications or inappropriately high doses) with regard to kidney function in patients with CKD under nephrology care. We also assessed the impact of the equation used to estimate GFR on the prevalence estimates. Methods Results The CKD-REIN cohort includes 3033 outpatients with CKD (eGFR between 15 and 60 ml min(-1) 1.73 m(-2)). We examined the daily doses of pharmacological agents prescribed at study entry. Inappropriate prescription was defined as the reported prescription of either a contraindicated drug or an indicated drug at an inappropriately high dose level with regard to the patient's GFR, as estimated with the CKD-EPI equation, the de-indexed CKD-EPI equation, or the Cockcroft-Gault (CG) equation. Multivariate logistic regression was used to assess the determinants of inappropriate prescription risk. At baseline, patients' median [interquartile range] number of drugs prescribed per patient was 8 [5-10]. Half of the patients had been prescribed at least one inappropriate drug. Anti-gout, cardiovascular agents and antidiabetic agents accounted for most of the inappropriate prescriptions. The percentage of inappropriate prescriptions varied from one GFR equation to another: 52% when using the CKD-EPI equation, 47% when using the de-indexed CKD-EPI equation and 41% with the CG equation. A multiple logistic regression analysis showed significantly higher odds ratios [95% confidence interval] for inappropriate prescriptions in male patients (1.28 [1.07; 1.53]), patients with diabetes (1.34 [1.06; 1.70]), those with a high BMI (1.58 [1.25; 1.99]), and those with a low GFR (10.2 [6.02; 17.3]). The risk of having at least one inappropriate prescription increased with the number of drugs per patient (P for trend \textless 0.0001) and therefore the odds ratio was 5.88 [4.17; 8.28] for those who received at least 11 prescribed medications compared to those who received fewer than 5. Conclusion Appendix Our results emphasize the complexity of drug management for CKD patients, for whom inappropriate prescription appears to be common.

Published
2018
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2. Laser induced breakdown spectroscopy: Challenges and Future

Author

Sabsabi, M., Doucet, F. R., Bouchard, P., Héon, R., Hamel, A., Laville, S., Gravel, J. F., and Canadian Association of Physicists/Association canadienne des physiciens et physiciennes

Abstract

2011 CAP Congress, Memorial University St John's Newfoundland, June 13-17, 2011, 2011-06-15, St John's Newfoundland, Canada

Published
2011

6. The PLASMONX Project for advanced beam physics experiments

Author

Alesini, D., Bellaveglia, M., Bertolucci, S., Boni, R., Boscolo, M., Castellano, M., Clozza, A., Dipirro, G., Drago, A., Esposito, A., Ferrario, M., Ficcadenti, L., Filippetto, D., Fusco, V., Gatti, G., Gallo, A., Ghigo, A., Incurvati, M., Ligi, C., Pellegrino, L., Preger, M., Ricci, R., Sanelli, C., Serio, M., Sgamma, F., Spataro, B., Stecchi, A., Stella, A., Tazzioli, F., Vaccarezza, C., Vescovi, M., Vicario, C., Aless, Ria, F., Bacci, A., Bonifacio, R., Broggi, F., Cola, M., Demartinis, C., Giove, D., Maroli, C., Mauri, M., Petrillo, V., Piovella, N., Pozzoli, R., Romè, M., Rossi, A. R., Serafini, L., Volpe, L., Levi, D., Mattioli, M., Musumeci, P., Medici, G., Pelliccia, D., Petrarca, M., Bottigli, U., Golosio, B., Oliva, P., Poggiu, A., Stumbo, S., Barbini, A., Baldeschi, W., Cecchetti, C. A., Galimberti, M., Giulietti, A., Giulietti, D., Gizzi, L. A., Koester, P., Labate, L., Laville, S., Rossi, A., Tomassini, P., Palumbo, Luigi, Mattioli, Mario Claudio, Petrarca, Massimo, Migliorati, Mauro, and Mostacci, Andrea

Subjects
X band
Published
2006

7. The project plasmonx for plasma acceleration experiments and a Thomson X-ray source at SPARC

Author

Alesini, D., Bellaveglia, M., Bertolucci, S., Biagini, Me, Boni, R., Boscolo, M., Castellano, M., Clozza, A., Di Pirro, G., Drago, A., Esposito, A., Ferrario, M., Ficcadenti, L., Filippetto, D., Fusco, V., Gallo, A., Giancarlo Gatti, Ghigo, A., Guiducci, S., Incurvati, M., Ligi, C., Marcellini, F., Migliorati, M., Mostacci, A., Palumbo, L., Pellegrino, L., Preger, M., Ricci, R., Sanelli, C., Serio, M., Sgamma, F., Spataro, B., Stecchi, A., Stella, A., Tazzioli, F., Vaccarezza, C., Vescovi, M., Vicario, C., Alessandria, F., Bacci, A., Bonifacio, R., Boscolo, I., Broggi, F., Cialdi, S., Demartinis, C., Giove, D., Maroli, C., Mauri, M., Petrillo, V., Piovella, N., Pozzoli, R., Rome, M., Serafini, L., Mattioli, M., Musumeci, P., Petrarca, M., Bottigli, U., Golosio, B., Oliva, P., Poggiu, A., Stumbo, S., Barbini, A., Baldeschi, W., Cecchetti, Ca, Galimberti, M., Giulietti, A., Giulietti, D., Gizzi, La, Koester, P., Labate, L., Laville, S., Rossi, A., Tomassini, P., and IEEE

Subjects
Physics, Interaction point, business.industry, Pulse duration, Plasma, Laser, Plasma acceleration, law.invention, Acceleration, Optics, Beamline, law, Cathode ray, Physics::Accelerator Physics, business
Abstract

We present the status of the project PLASMONX, recently approved by INFN. This project, based on a collaboration between INFN and CNR-IPCF, aims at a long term upgrade of the SPARC system with the goal to develop at LNF an integrated facility for advanced beam-laser-plasma research in the field of advanced acceleration techniques and ultra-bright X-ray radiation sources and related applications. The project, in its first phase, foresees the development at LNF of a High Intensity Laser Laboratory (HILL) whose main component is a 100 TW-class Ti: Sa laser system synchronized to the SPARC photo-injector. Experiments of self-injection and acceleration of electrons into laser driven plasma waves will be conducted at HILL-LNF, early in this first project phase. Eventually an additional beam line will be built in the SPARC bunker in order to transport the SPARC electron beam at an interaction point, where a final focus system will allow to conduct experiments either of laser-beam co-propagation in plasma waves for high gradient acceleration, or experiments of laser-beam head-on collisions to develop a Thomson source of bright ultra-short X-ray radiation pulses, with X-ray energies tunable in the range 20 to 1000 keV and pulse duration from 30 fs to 20 ps. Preliminary simulations of plasma acceleration with self-injection are illustrated, as well as external injection of the SPARC electron beam.

Published
2005

9. Design study for advanced acceleration experiments and monochromatic X-ray production at SPARC

Author

Alesini, D., Bertolucci, S., Benedetti, G., Biagini, M., Biscari, C., Boni, R., Boscolo, M., Michele Castellano, Clozza, A., Delle Monache, G., Di Pirro, G., Drago, A., Esposito, A., Ferrario, M., Fusco, V., Gallo, A., Ghigo, A., Guiducci, S., Incurvati, M., Ligi, C., Marcellini, F., Migliorati, M., Milardi, C., Mostacci, A., Palumbo, L., Pellegrino, L., Preger, M., Raimondi, P., Ricci, R., Rotundo, U., Sanelli, C., Serio, M., Sgamma, F., Spataro, B., Stecchi, A., Stella, A., Tazzioli, F., Vaccarezza, C., Vescovi, M., Vicario, C., Zobov, M., Alessandria, F., Bacci, A., Bonifacio, R., Boscolo, I., Broggi, F., Cialdi, S., Demartinis, C., Giove, D., Maroli, C., Mauri, M., Petrillo, V., Piovella, N., Pozzoli, R., Rome, M., Serafini, L., Bottigli, U., Golosio, B., Olivia, P., Poggiu, A., Stumbo, S., Barbini, A., Baldeschi, W., Cecchetti, C. A., Galimberti, M., Guilietti, A., Gizzi, L. A., Koester, P., Labate, L., Laville, S., Rossi, A., and Tomassini, P.

10. The PLASMONX Project for advanced beam physics experiments

Author

Alesini, D., Bellaveglia, M., Bertolucci, S., Boni, R., Boscolo, M., Castellano, M., Clozza, A., Dipirro, G., Drago, A., Esposito, A., Ferrario, M., Ficcadenti, L., Filippetto, D., Fusco, V., Gatti, G., Gallo, A., Ghigo, A., Incurvati, M., Ligi, C., Marcellini, F., Migliorati, M., Mostacci, A., Palumbo, L., Pellegrino, L., Preger, M., Ricci, R., Sanelli, C., Serio, M., Sgamma, F., BRUNO SPATARO, Stecchi, A., Stella, A., Tazzioli, F., Vaccarezza, C., Vescovi, M., Vicario, C., Alessandria, F., Bacci, A., Bonifacio, R., Broggi, F., Cola, M., Demartinis, C., Giove, D., Maroli, C., Mauri, M., Petrillo, V., Piovella, N., Pozzoli, R., Romè, M., Rossi, A. R., Serafini, L., Volpe, L., Levi, D., Mattioli, M., Musumeci, P., Medici, G., Pelliccia, D., Petrarca, M., Bottigli, U., Golosio, B., Oliva, P., Poggiu, A., Stumbo, S., Barbini, A., Baldeschi, W., Cecchetti, C. A., Galimberti, M., Giulietti, A., Giulietti, D., Gizzi, L. A., Koester, P., Labate, L., Laville, S., Rossi, A., and Tomassini, P.

11. Maladaptation au changement climatique : commencer par bien faire ce que l’on fait mal

Author

Magnan, Alexandre, Duvat, Virginie, Institut du Développement Durable et des Relations Internationales (IDDRI), Institut d'Études Politiques [IEP] - Paris, LIttoral ENvironnement et Sociétés - UMRi 7266 (LIENSs), Université de La Rochelle (ULR)-Centre National de la Recherche Scientifique (CNRS), A. Euzen, B. Laville, S. Thiébault (Eds.), and ANR-15-CE03-0003,STORISK,Les petites îles face au changement climatique: vers des trajectoires de risque et d'adaptation(2015)

Subjects
Adaptation au changement climatique, [SDE.MCG]Environmental Sciences/Global Changes, [SHS.GEO]Humanities and Social Sciences/Geography, [SDE.ES]Environmental Sciences/Environmental and Society, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2017

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