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Additional file 1: Table S1. linear regression of anastomotic leakage (AL) and nutritional indicators. Table S2. logistic regression of type of operation and complications.

Double LCC compensation resonant converter is effectively applicable to inductively coupled energy transfer, for the advantages of perfect symmetry and simple design. However, the system gain characteristics and output characteristics of the circuit overall structure were ignored in the previous study of double LCC compensation converter. In this paper, impedance analysis method is used to determine gain characteristic of system, finding that the system has a constant current source output characteristics in addition to purely resistance at a fixed frequency point, which is independent of the load and the coupling coefficient. Two methods of parameters optimization are proposed in this paper, which are used to realize ZVS (Zero Voltage Switch) for the full-bridge inverter. Subsequently, the effects of different methods on the gain characteristics are compared. A design idea of a double LCC compensation topology under different working conditions is provided. The whole optimization method is simple, accurate and practical. Finally, a 3.3 kW double LCC resonant converter is completed. The characteristics of the converter and optimization method are verified from simulation and experimental results.

Growth factors are a class of cytokines that stimulate cell growth and are widely used in clinical practice, such as wound healing, revascularization, bone repair, and nervous system disease. However, free growth factors have a short half-life and are instable in vivo. Therefore, the search of excellent carriers to enhance sustained release of growth factors in vivo has become an area of intense research interest. The development of controlled-release systems that protect the recombinant growth factors from enzymatic degradation and provide sustained delivery at the injury site during healing should enhance the growth factor’s application in tissue regeneration. Thus, this study reviews current research on commonly used carriers for sustained release of growth factors and their sustained release effects for preservation of their bioactivity and their accomplishment in tissue engineering approaches.

C18H13F3OS, orthorhombic, P212121 (no. 19), a = 7.9402(8) Å, b = 15.231(2) Å, c = 25.643(3) Å, V = 3101.2 Å3, Z = 8, Rgt(F) = 0.0642, wRref(F2) = 0.1978, T = 293 K.