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3 results on '"Ligand receptor"'

1. A structural classification of substrate-binding proteins

Subjects
Ligand receptor, TREPONEMA-PALLIDUM TROA, Structural classification, TRAP TRANSPORTERS, MALTOSE-BINDING, ABC TRANSPORTER, DIFFERENT MECHANISMS, ASSOCIATIVE PROPERTIES, ACTIVE-TRANSPORT, ESCHERICHIA-COLI, transporter, LIGAND-BINDING, ATP-binding cassette transporter, Substrate-binding protein, CRYSTAL-STRUCTURE, Tripartite ATP-independent periplasmic
Abstract

Substrate-binding proteins (SBP) are associated with a wide variety of protein complexes. The proteins are part of ATP-binding cassette transporters for substrate uptake, ion gradient driven transporters, DNA-binding proteins, as well as channels and receptors from both pro-and eukaryotes. A wealth of structural and functional data is available on SBPs, with over 120 unique entries in the Protein Data Bank (PDB). Over a decade ago these proteins were divided into three structural classes, but based on the currently available wealth of structural data, we propose a new classification into six clusters, based on features of their three-dimensional structure. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Published
2010
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2. A structural classification of substrate-binding proteins

Author

Sander H. J. Smits, Bert Poolman, Ronnie P.-A. Berntsson, Dirk Jan Slotboom, and Lutz Schmitt

Subjects
Models, Molecular, Ligand receptor, Tripartite ATP-independent periplasmic transporter, Protein Conformation, Structural classification, TRAP TRANSPORTERS, MALTOSE-BINDING, Biophysics, Protein Data Bank (RCSB PDB), Maltose binding, ATP-binding cassette transporter, Biology, ASSOCIATIVE PROPERTIES, Biochemistry, DNA-binding protein, ACTIVE-TRANSPORT, 03 medical and health sciences, Protein structure, Structural Biology, Genetics, Animals, CRYSTAL-STRUCTURE, Databases, Protein, Molecular Biology, 030304 developmental biology, 0303 health sciences, TREPONEMA-PALLIDUM TROA, 030306 microbiology, ABC TRANSPORTER, Membrane Proteins, DIFFERENT MECHANISMS, Cell Biology, computer.file_format, Structural Classification of Proteins database, Protein Data Bank, ESCHERICHIA-COLI, Multiprotein Complexes, transporter, LIGAND-BINDING, Substrate-binding protein, Carrier Proteins, computer, Signal Transduction, Tripartite ATP-independent periplasmic
Abstract

Substrate-binding proteins (SBP) are associated with a wide variety of protein complexes. The proteins are part of ATP-binding cassette transporters for substrate uptake, ion gradient driven transporters, DNA-binding proteins, as well as channels and receptors from both pro-and eukaryotes. A wealth of structural and functional data is available on SBPs, with over 120 unique entries in the Protein Data Bank (PDB). Over a decade ago these proteins were divided into three structural classes, but based on the currently available wealth of structural data, we propose a new classification into six clusters, based on features of their three-dimensional structure. (C) 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Published
2010

3. Olfactory receptor structure prediction and classification of ligand-receptor affinities

Author

Téletchéa, Stéphane, Marin, Antoine, Gibrat, Jean-François, Pajot, Edith, Sanz, Guenhaël, Unité Mathématique Informatique et Génome (MIG), Institut National de la Recherche Agronomique (INRA), and Neurobiologie de l'Olfaction et de la Prise Alimentaire (NOPA)

Subjects
LIGAND RECEPTOR, [SDV]Life Sciences [q-bio], OLFACTORY RECEPTOR, [INFO]Computer Science [cs], STRUCTURE PREDICTION, [MATH]Mathematics [math], ComputingMilieux_MISCELLANEOUS
Abstract

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Published
2006

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