Search

Flame-retardant reed inorganic particleboard was prepared by hot-pressing with reed particles as a reinforcing material and using magnesite cement as an inorganic adhesive. The effects of inorganic sizing amount, density, and hot-pressing temperature and time on the properties of reed inorganic particleboard were investigated by orthogonal testing. Particleboard properties were tested and characterized by means of a universal mechanical testing machine, scanning electronic microscopy (SEM), X-ray diffraction (XRD), and cone calorimetry. The results showed that the mechanical properties of particleboard prepared under conditions of 60 percent sizing capacity, 100°C hot-pressing temperature, 15 minutes hot-pressing time, and 1.2 g/cm3 density were the best, reaching the national standard for cement particleboard. At 60 percent sizing, the characteristic peak value of inorganic adhesive hydrate crystal phase was the largest, the crystallization area dense and orderly, and the coating effect on shavings good; these attributes confirmed the trend of mechanical properties of reed shavings board increasing with sizing amount. Thus, the sizing amount had a significant influence on flame retardancy and smoke suppression performance of this particleboard. With an increased application amount, the heat release and total heat release rates of the particleboard and total smoke generation rate showed decreasing trends. Additionally, when the ignition time was delayed, the flame retardancy and smoke suppression performance of the particleboard was enhanced.

Objective To explore the possible molecular regulation mechanism of COPB2 on human osteosarcoma cells based on the bioinformatics analysis of ingenuity pathway analysis (IPA). Methods RT-qPCR was used to detect the expression levels of COPB2 in human osteosarcoma cell lines U-2OS, MG-63, HOS and Saos-2. U-2OS was used as the research object and divided into silence group (KD) and control group (NC). U-2OS cells were infected by green fluorescent protein-labeled lentivirus and the KD group contained COPB2 silenced sequence. Human gene expression profiling microarray was used to detect the difference in gene expression profile of U-2OS cells after COPB2 silencing. The detection information was input into the IPA software for bioinformatics analysis, including classical pathway analysis, upstream regulation analysis, disease function analysis, regulatory effect analysis and interaction network analysis. Results COPB2 had a high expressive abundance in four human osteosarcoma cell lines. There were significant differences in the expression of 1393 genes between KD group and NC group; 831 genes were up-regulated and 562 genes were down-regulated. After COPB2 knockdown, the inhibition of angiogenesis by TSP1 pathway and acute phase response pathway were significantly activated, while cyclins and cell cycle regulation pathway were significantly inhibited. COPB2 mainly affected neoplasia, invasion and anoikis of osteosarcoma cells. Conclusion COPB2 is highly expressed in human osteosarcoma cell lines, and might be involved in the development of osteosarcoma through cyclins and cell cycle regulation pathway. In addition, COPB2 is associated with neoplasia, invasion and anoikis of osteosarcoma cells.

Additional file 1: Fig S1. Knockdown of MIAC promotes RCC cell proliferation and migration. (A, B) The relative expression level of MIAC was significantly down-regulated by MIAC knockdown. Knockdown of MIAC promotes RCC cell proliferation (C) and cell migration (D). (E) Knockdown of MIAC promotes RCC cell cycle arrest or inhibits cell apoptosis (F). *P

Objective To evaluate the safety and efficacy of percutaneous vertebroplasty(PVP) in the treatment of spinal metastases with incomplete posterior wall. Methods We retrospectively analyzed 106 spinal metastases patients with incomplete posterior wall treated with PVP. Demographic and pre- and post-operative clinical characteristics were reviewed. Pain relief and functional activities recovery, systemic complications and the local leakage of the bone cement were evaluated before and after operation. Results All patients successfully underwent surgery, VAS score was 3.0(2.0-5.0) after operation and decreased for 5.0(3.0-7.0). Among 70 patients who received the assessment, 10 patients had a better Barthel Index(BI) and 46 patients were with the same activity of daily living. None had systemic complications during the injection of bone cement. Among the 160 vertebrae with incomplete vertebral posterior wall, 39(24.4%) vertebrae showed bone cement leakage and 7(4.4%) vertebrae were intraspinal leakage. None had bone cement leakage-related neurological symptoms after operation. Conclusion Percutaneous vertebroplasty is effective and safe in the treatment of spinal metastases with incomplete posterior wall.

In the present paper, EXAFS and Mossbauer spectroscopies have been used to study the structure of iron in Fe 2 O 3 P 2 O 5 glasses, Na 2 OFe 2 O 3 P 2 O 5 glasses and the samples which are obtained from heat-treated iron metaphosphate glass. The results indicate that ferric and ferrous ions are present in the phosphate glasses, and Fe 3+ ions are coordinated with both four and six oxygens, but Fe 2+ ions are only in six-coordination. The proportion of each kind of iron ion to the total iron ions changes with a composition of the glasses and heat treatment conditions of the samples. The coordination number of Fe 3+ ions in an iron phosphate glass is lower than in the iron phosphate crystal with the same composition.

The coordination number and distances around a Ge atom in binary oxide glasses BiO1.5-GeO2 and PO2.5-GeO2 have been measured by EXAFS. The results show that Ge-O tetrahedron network in GeO2 rich BiO1.5-GeO2 glass is much like that in amorphous GeO2, but that in PO2.5-GeO2 glass it is more disordered.

The EXAFS of Cu atoms in Na2O-CuO-B2O3 glass systems have been measured in a laboratory EXAFS facility. In order to achieve good EXAFS data, gas proportional counter for I0 and scintillation detector for I are used simultaneously to cancel out emission lines and the pulse height discriminator to out off harmornic. The local structure parameters around Cu atom have been determined by using of a common analysis process for EXAFS data. The monoolinic crystalline CuO is used as a standard specimen. The results show that the coordination number of Cu atom and the length of Cu-O bond in Na2O-CuO-B2O3 glass systems is respectively four and 1.92A as near as those in crystalline CuO. It can be concluded that Cu2+ ions still exist in the glassy network with the form of (CuO4) tetrahedron. The coordination number of Cu atom and the length of Cu-O bond don't change with increased CuO content in the glass.