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3 results on '"Londono, MC"'

2. EFFICACY AND SAFETY OF BUDESONIDE AS FIRST LINE TREATMENT IN PATIENTS WITH AUTOIMMUNE HEPATITIS: SPANISH MULTICENTER STUDY

Author

Diaz-Gonzalez, A, Hernandez-Guerra, M, Gomez, E, Sapena, V, Perez-Medrano, I, Del Barrio, M, Escude, L, Barciela, MR, Barreira-Diaz, A, Soria, A, Molina, E, Ferre-Aracil, C, El Hajra, I, Arencibia, AC, Cunill, RMM, Gomez-Camarero, J, Conde, I, Mateos, B, Horta, D, Estevez, P, Lopez, C, Navascues, CA, Zamora, J, Garcia-Retortillo, M, Fernandez, A, Garcia, JC, and Londono, MC

Published
2021

3. Potential drug-drug interactions of OMBITASVIR, PARITAPREVIR/ritonavir +/- DASABUVIR +/- ribavirin in clinical practice

Author

Gonzalez-Colominas, E, Londono, MC, Morillas, RM, Torras, X, Mojal, S, Lens, S, Lopez, D, Gallego, A, Marino, Z, Ardevol, M, Pages, N, Sola, R, and Carrion, JA

Subjects
Ritonavir, Hepatitis C virus, Paritaprevir, Dasabuvir, Drug-drug interactions, Ombitasvir
Abstract

Background & AimsDrug-drug interactions (DDIs) with ombitasvir/paritaprevir/ritonavir with or without dasabuvir and with or without ribavirin (OBV/PTV/rDSVRBV) are common in clinical trials. Our aim was to analyze the prevalence and management of potential DDIs and adverse events (AEs) related to DDIs in patients with chronic hepatitis C (CHC) receiving OBV/PTV/rDSV +/- RBV in clinical practice. Methods177 CHC patients started OBV/PTV/r +/- DSV +/- RBV in 4 Spanish hospitals and were screened for potential DDIs using the University of Liverpool database. Patients were classified according to the most serious potential DDIs at baseline and AEs during therapy. ResultsAt least one potential DDI was found in 110 (62.1%) patients: 100 (56.5%) had at least one manageable potential DDI and 10 (5.6%) at least one contraindicated. Patients with potential DDIs were receiving a higher number of concomitant drugs (4 vs. 2, P

Published
2018

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