93 results on '"Lopamudra Ray"'
Search Results
2. Evidence-based impact projections of single-dose human papillomavirus vaccination in India: a modelling study
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Irene Man, Damien Georges, Tiago M de Carvalho, Lopamudra Ray Saraswati, Prince Bhandari, Ishu Kataria, Mariam Siddiqui, Richard Muwonge, Eric Lucas, Johannes Berkhof, Rengaswamy Sankaranarayanan, Johannes A Bogaards, Partha Basu, Iacopo Baussano, APH - Methodology, Epidemiology and Data Science, CCA - Cancer Treatment and quality of life, and AII - Infectious diseases
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Human papillomavirus 16 ,Oncology ,Papillomavirus Infections ,Humans ,Uterine Cervical Neoplasms ,India ,Female ,Papillomavirus Vaccines - Abstract
BACKGROUND: Despite the high burden of cervical cancer, access to preventive measures remains low in India. A single-dose immunisation schedule could facilitate the scale-up of human papillomavirus (HPV) vaccination, contributing to global elimination of cervical cancer. We projected the effect of single-dose quadrivalent HPV vaccination in India in comparison with no vaccination or to a two-dose schedule.METHODS: In this modelling study, we adapted an HPV transmission model (EpiMetHeos) to Indian data on sexual behaviour (from the Demographic and Health Survey and the Indian National AIDS Control Organisation), HPV prevalence data (from two local surveys, from the states of Tamil Nadu and West Bengal), and cervical cancer incidence data (from Cancer Incidence in Five Continents for the period 2008-12 [volume XI], and the Indian National Centre for Disease Informatics and Research for the period 2012-16). Using the model, we projected the nationwide and state-specific effect of HPV vaccination on HPV prevalence and cervical cancer incidence, and lifetime risk of cervical cancer, for 100 years after the introduction of vaccination or in the first 50 vaccinated birth cohorts. Projections were derived under a two-dose vaccination scenario assuming life-long protection and under a single-dose vaccination scenario with protection duration assumptions derived from International Agency for Research on Cancer (IARC) India vaccine trial data, in combination with different vaccination coverages and catch-up vaccination age ranges. We used two thresholds to define cervical cancer elimination: an age-standardised incidence rate of less than 4 cases per 100 000 woman-years, and standardised lifetime risk of less than 250 cases per 100 000 women born.FINDINGS: Assuming vaccination in girls aged 10 years, with 90% coverage, and life-long protection by two-dose or single-dose schedule, HPV vaccination could reduce the prevalence of HPV16 and HPV18 infection by 97% (80% UI 96-99) in 50 years, and the lifetime risk of cervical cancer by 71-78% from 1067 cases per 100 000 women born under a no vaccination scenario to 311 (80% UI 284-339) cases per 100 000 women born in the short term and 233 (219-252) cases per 100 000 women born in the long term in vaccinated cohorts. Under this scenario, we projected that the age-standardised incidence rate threshold for elimination could be met across India (range across Indian states: 1·6 cases [80% UI 1·5-1·7] to 4·0 cases [3·8-4·4] per 100 000 woman-years), while the complementary threshold based on standardised lifetime risk was attainable in 17 (68%) of 25 states, but not nationwide (range across Indian states: 207 cases [80% UI 194-223] to 477 cases [447-514] per 100 000 women born). Under the considered assumptions of waning vaccine protection, single-dose vaccination was projected to have a 21-100% higher per-dose efficiency than two-dose vaccination. Single-dose vaccination with catch-up for girls and women aged 11-20 years was more impactful than two-dose vaccination without catch-up, with reduction of 39-65% versus 38% in lifetime risk of cervical cancer across the ten catch-up birth cohorts and the first ten routine vaccination birth cohorts.INTERPRETATION: Our evidence-based projections suggest that scaling up cervical cancer prevention through single-dose HPV vaccination could substantially reduce cervical cancer burden in India.FUNDING: The Bill & Melinda Gates Foundation.
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- 2022
3. Exogenous N-acetylated chitooligosaccharides application improves osmotic stress and water deficit tolerance in Oryza sativa (cv. Swarna Sub-1) inducing seed germination, seedling growth, and biochemical activities
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Himadri Tanaya Behera, Abhik Mojumdar, Smrutiranjan Das, Mrunmay Kumar Giri, and Lopamudra Ray
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Physiology ,Genetics ,Cell Biology ,Plant Science ,Ecology, Evolution, Behavior and Systematics - Published
- 2022
4. l-Asparaginase producing novel Streptomyces sp. HB2AG: optimization of process parameters and whole genome sequence analysis
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Gupteswar Rath, Suchismita Nivedita, Subhransu Sekhar Behera, Himadri Tanaya Behera, Sudhansu Kumar Gouda, Vishakha Raina, K. Gopinath Achary, Susanta K. Behera, and Lopamudra Ray
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Environmental Science (miscellaneous) ,Agricultural and Biological Sciences (miscellaneous) ,Biotechnology - Published
- 2023
5. Whole genome sequencing of a novel chitinolytic Streptomyces sp. RB7AG reveals it’s chitosan production potential: optimization of the process through Taguchi experimental design
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Subhransu Sekhar Behera, Suchismita Nivedita, Smrutiranjan Das, Himadri Tanaya Behera, Abhik Mojumdar, and Lopamudra Ray
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Environmental Science (miscellaneous) ,Agricultural and Biological Sciences (miscellaneous) ,Biotechnology - Published
- 2023
6. Planning for injecting drug use as a means to prevent risky injection behavior
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Mary Philip Sebastian, Avina Sarna, Lopamudra Ray Saraswati, Vartika Sharma, Ira Madan, Waimar Tun, and Ibou Thior
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Health (social science) ,Medicine (miscellaneous) - Published
- 2022
7. Effect of Statins on the Inflammatory Markers in Patients with Coronary Artery Disease
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Sujatha Mahadevarao Premnath, Sunil Kumar Nanda, Lopamudra Ray, and Mark Chirstopher Arokiaraj
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General Medicine - Abstract
Introduction Atherosclerosis mediated by inflammatory markers is the corner stone in the pathology of coronary artery disease (CAD). Hyperlipidemia, one of the risk factors is treated with statins. Statins also have a pleotropic role in reducing inflammation. Effect of statins on two inflammatory markers pentraxin 3(PTX 3) and high sensitivity C-reactive protein (hs-CRP) is explored in this study. Aim This article estimates the levels of serum PTX 3 and hs-CRP in CAD patients with and without statin therapy and correlates the levels with low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c) in CAD patients without statin therapy. Material and Methods This was a cross-sectional study conducted on 62 patients with CAD diagnosed by coronary angiogram. They were divided into two groups. Group I were the CAD patients on statin therapy and group II were CAD patients who never had any lipid lowering drugs irrespective of their lipid values. Serum PTX3, hs-CRP, and lipid profile were estimated in these groups. Comparison between the groups was done using Student's t-test and correlation analyzed using Pearson's correlation. Results Serum PTX 3 and hs-CRP levels were higher than the reference range in both the groups. But group I showed significantly low PTX 3 levels (p-value = 0.032) compared with group II. There was a significant positive relationship between PTX 3 and LDL-c (p = 0.003) in group II. Conclusion CAD patients on statin therapy have lower vessel wall inflammation compared with patients without statin therapy.
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- 2023
8. Biodegradation of Chitin Extracted from Labeo catla Fish Scales and Production of Chitooligosaccharides by Novel Chitinolytic Bacteria Streptomyces chilikensis RC1830
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Lopamudra Ray, Abhik Mojumdar, Himadri Tanaya Behera, and Smruti Das
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Streptomyces chilikensis ,biology ,Microorganism ,Aquatic Science ,engineering.material ,Biodegradation ,biology.organism_classification ,Catla ,chemistry.chemical_compound ,chemistry ,Chitin ,engineering ,Food science ,Biopolymer ,Cellulose ,Microbial biodegradation ,Food Science - Abstract
Chitin, next to cellulose, is by far the most common biopolymer found in nature which is relatively resistant to degradation. Chitinolytic microorganisms can break glycosidic bonds in chitin to oli...
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- 2021
9. Extremozymes: Biocatalysts From Extremophilic Microorganisms and Their Relevance in Current Biotechnology
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Khushbu Kumari Singh and Lopamudra Ray
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Chemistry ,business.industry ,Microorganism ,Relevance (information retrieval) ,Current (fluid) ,business ,Halophile ,Biotechnology - Published
- 2021
10. Microbial Intervention in Sustainable Production of Biofuels and Other Bioenergy Products
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Chiranjib Mohapatra, Abhik Mojumdar, Smruti Das, Lopamudra Ray, and Himadri Tanaya Behera
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Intervention (law) ,Bioenergy ,Natural resource economics ,Biofuel ,Business ,Sustainable production - Published
- 2021
11. Lithobiontic Ecology: Stone Encrusting Microbes and their Environment
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Lopamudra Ray, Himadri Tanaya Behera, and Abhik Mojumdar
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Ecology ,Ecology (disciplines) ,Environmental science - Published
- 2021
12. Correction to: Polyhydroxyalkanoate recovery from newly screened Bacillus sp. LPPI-18 using various methods of extraction from Loktak Lake sediment sample
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Seid Mohammed and Lopamudra Ray
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Genetics ,Biotechnology - Published
- 2022
13. Polyhydroxyalkanoate recovery from newly screened Bacillus sp. LPPI-18 using various methods of extraction from Loktak Lake sediment sample
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Seid Mohammed and Lopamudra Ray
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Genetics ,Biotechnology - Abstract
Background Nowadays, the conventional plastic wastes are very challenging to environments and its production cost also creates an economic crisis due to petrochemical-based plastic. In order to solve this problem, the current studies were aimed at screening and characterizing these polyhydroxyalkanoate (PHA)-producing isolates and evaluating the suitability of some carbon source for newly screened PHA-producing isolates. Material and methods Some carbon sources such as D-fructose, glucose, molasses, D-ribose and sucrose were evaluated for PHA production. Data were analyzed using SPSS version 20. The 16SrRNA gene sequence of these isolates was performed. These newly isolated taxa were related to Bacillus species. It was designated as Bacillus sp. LPPI-18 and affiliated Bacillus cereus ATCC 14577T (AE01687) (99.10%). Paenibacillus sp. 172 (AF273740.1) was used as an outgroup. Results Bacillus sp. LPPI-18 is a gram-positive, rod-shaped, endospore former, and citrate test positive. This isolate showed positive for amylase, catalase, pectinase, and protease test. They produced intracellular PHA granules when this isolate was stained with Sudan Black B (SBB) and Nile blue A (NBA) preliminary and specific staining dyes, respectively. Both temperature and pH used to affect polyhydroxyalkanoates (PHA) productivity. Bacteria are able to reserve PHA in the form of granules during stress conditions. This isolate produces only when supplied with carbon sources. More PHA contents (PCs) were obtained from glucose, molasses, and D-fructose. In this regard, the maximum mean value of PC was obtained from glucose (40.55±0.7%) and the minimum was obtained from D-ribose (12.4±1.4%). Great variations (P≤0.05) of PCs were observed among glucose and sucrose, molasses and sucrose, and D-fructose and sucrose carbon sources for PHA productivity (PP) of cell dry weight (CDW) g/L. After extraction, PHA film was produced for this typical isolate using glucose as a sole carbon source. Fourier transform infrared spectrum was performed for this isolate and showed the feature of polyester at 1719.64 to 1721.16 wavelengths for these extracted samples. The peak of fingerprinting (band of carboxylic acid group) at this wavelength is a characteristic feature of polyhydroxybutyrate (PHB) and corresponds to the ester functional group (C=O). Conclusion In this study, newly identified Bacillus sp. LPPI-18 is found to be producing biodegradable polymers that are used to replace highly pollutant conventional plastic polymers. This isolate is also used to employ certain cost-effective carbon sources for the production of PHA polymers. Graphical Abstract
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- 2022
14. Exploration of genomic and functional features of chitinolytic bacterium Streptomyces chilikensis RC1830, isolated from Chilika Lake, India
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Himadri Tanaya Behera, Abhik Mojumdar, Khushbu Kumari, Sudhansu Kumar Gouda, Smrutiranjan Das, and Lopamudra Ray
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Original Article ,Environmental Science (miscellaneous) ,Agricultural and Biological Sciences (miscellaneous) ,Biotechnology - Abstract
Streptomyces chilikensis RC1830 was previously isolated as a novel chitinolytic streptomycete from Chilika Lake, Odisha, India. The strain RC1830 is a representative member of the soil-dwelling, filamentous Streptomyces group that produces the majority of natural antibiotics and secondary metabolites. The objective of this work was to assess the chitin degradation ability and whole-genome sequence of Streptomyces chilikensis RC1830. TLC analysis of the fermentation product revealed that strain RC1830 can convert shrimp shell colloidal chitin to N-acetylated chitooligosaccharides (N-AcCOS). A genome-wide investigation of RC1830 was also carried out to investigate the genetic basis for chitin breakdown. The result showed that the RC1830 genome possesses a chromosome with 7,121,774 bp (73.2% GC). The genome consists of 6807 coding sequences, 69 tRNA, and 3 rRNA genes. Furthermore, carbohydrate-active enzyme (CAZyme) analysis revealed that RC1830 has 89 glycoside hydrolase family genes, which could modulate the enzymes involved in the degradation of chitin ultimately producing industrially important COS. The whole-genome information of RC1830 could emphasize the mechanism involved in the RC1830’s chitin breakdown activity, endowing RC1830 with a promising alternative for COS production. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13205-022-03184-5.
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- 2022
15. Hydoxylated β- and δ-Hexacholorocyclohexane metabolites infer influential intrinsic atomic pathways interaction to elicit oxidative stress-induced apoptosis for bio-toxicity
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Khushbu Singh, Suresh K. Verma, Paritosh Patel, Pritam Kumar Panda, Adrija Sinha, Biswadeep Das, Vishakha Raina, Mrutyunjay Suar, and Lopamudra Ray
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Oxidative Stress ,Soil ,Biodegradation, Environmental ,Animals ,Humans ,Apoptosis ,Biochemistry ,Hexachlorocyclohexane ,Zebrafish ,General Environmental Science - Abstract
Hexachlorocyclohexane (HCH) has been recognized as an effective insecticide to protect crops against grasshoppers, cohort insects, rice insects, wireworms, and other agricultural pests and; for the control of vector-borne diseases such as malaria. It is a cyclic, saturated hydrocarbon, which primarily exists as five different stable isomers in the environment. Though the use of HCH is banned in most countries owing to its adverse effects on the environment, its metabolites still exist in soil and groundwater, because of its indiscriminate applications. In this study, a dose-dependent toxicity assay of the HCH isomers isolated from soil and water samples of different regions of Odisha, India was performed to assess the in vivo developmental effects and oxidative stress in zebrafish embryos. Toxicity analysis revealed a significant reduction in hatching and survivability rate along with morphological deformities (edema, tail malformations, spinal curvature) upon an increase in the concentration of HCH isomers; beta isomer exhibiting maximum toxicity (p 0.05). Oxidative stress assay showed that ROS and apoptosis were highest in the fish exposed to β-2 and δ-2 isomers of HCH in comparison to the untreated one. Zebrafish proved to be a useful biological model to assess the biological effects of HCH isomers. In addition, the results suggest the implementation of precautionary measures to control the use of organochlorine compounds that can lead to a decrease in the HCH isomers in the field for a healthier environment.
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- 2022
16. Optimization of the culture conditions for production of Polyhydroxyalkanoate and its characterization from a new Bacillus cereus sp. BNPI-92 strain, isolated from plastic waste dumping yard
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Lopamudra Ray, Aman Dekebo, Seid Mohammed, and Himadri Tanaya Behera
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Polymers ,Bacillus cereus ,chemistry.chemical_element ,02 engineering and technology ,Biochemistry ,Gas Chromatography-Mass Spectrometry ,Polyhydroxyalkanoates ,03 medical and health sciences ,chemistry.chemical_compound ,Dry weight ,Structural Biology ,Methylene ,Molecular Biology ,Phylogeny ,030304 developmental biology ,Waste Products ,0303 health sciences ,Strain (chemistry) ,Bran ,biology ,Spectrum Analysis ,Extraction (chemistry) ,Genomics ,General Medicine ,021001 nanoscience & nanotechnology ,biology.organism_classification ,Carbon ,Waste Disposal Facilities ,Phenotype ,chemistry ,Fermentation ,Sugars ,0210 nano-technology ,Plastics ,Genome, Bacterial ,Nuclear chemistry - Abstract
The aim of this study was to optimize the culture conditions for production, recovery and characterization of polyhydroxyalkanoate (PHA) from potential Bacillus cereus strain BNPI-92. Cost effective carbon sources such as crude oil (CO), rice bran (RB), sugar cane molasses (SCM) and wheat bran (WB) were evaluated for PHA production using the isolate. Higher cell dry weight (CDW) (g/L), PHA concentration (P conc.) (g/L) PHA contents (PC) (%) and PHA synthesis rate (PSR) were obtained from Glucose (60.67% w/v) as a carbon source at 37 °C and pH 7 using Taguchi DOE methods. The polymer was characterized by FTIR and its functional groups (C=O) (1719.41 cm−1 wavenumber) was a characteristic feature of PHB polymer. For 1HNMR, signals of methyne (CH) (5.28 ppm), methylene (-CH2-) (2.45 ppm) and methyl (CH3) (1.27 ppm) and copolymers were predicted. Copolymers such as P (3HB-co-3 HV) and P(3HB-co-3HHX) i.e. characteristic feature of PHB were obtained from a sample of glucose, WB, and RB, respectively. XRD pattern also confirmed the presence of PHA. The major compounds obtained from GC/MS analysis of the polymer recovered from the isolate BNP-92 were 2-butenoic acid, methyl ester (8.6%), ethyl cyclopropanecarboxylate (45.99%), 1-Undecanol (10.18%) which corresponds to and have produced from PHA after thermal degradation.
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- 2020
17. Extraction and Preliminary Characterization of Potential Antibacterial Agent from Potential Streptomyces cinereoruber sp. Isolated from an Chilika Lake
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Lopamudra Ray, Anjani Kumar Upadhyay, Debasmita Chatterjee, and Madhuri Swain
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Chromatography ,Complementary and alternative medicine ,Chemistry ,Extraction (chemistry) ,Pharmaceutical Science ,Pharmacology (medical) ,Streptomyces cinereoruber ,Antibacterial agent - Published
- 2020
18. ‘ Know‐Can ’ gap: gap between knowledge and skills related to childhood diarrhoea and pneumonia among frontline workers in rural Uttar Pradesh, India
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John Anthony, Prince Bhandari, Ashutosh Mishra, Karol Krotki, Lopamudra Ray Saraswati, Punit Kumar Mishra, Lorine Pelly, A B Rai, Maryanne Crockett, Margaret Baker, Mrunal Shetye, Ambrish Kumar Chandan, and John D. Kraemer
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Adult ,Male ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,education ,030231 tropical medicine ,Video Recording ,India ,Early detection ,Interviews as Topic ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Humans ,Medicine ,Social determinants of health ,Child ,Accreditation ,Community Health Workers ,business.industry ,Infant, Newborn ,Public Health, Environmental and Occupational Health ,Infant ,Pneumonia ,medicine.disease ,Cross-Sectional Studies ,Infectious Diseases ,Child, Preschool ,Family medicine ,Diarrhea, Infantile ,Female ,Parasitology ,Rural Health Services ,business ,Uttar pradesh - Abstract
In India, frontline workers (FLWs) - public accredited social health activists (ASHAs) and private rural medical providers (RMPs) - are important for early detection and treatment of childhood diarrhoea and pneumonia. This cross-sectional study aims to measure knowledge and skills, and the gap between the two ('know-can' gap), regarding assessment of childhood diarrhoea with dehydration and pneumonia among FLWs, and to explore factors associated with them.We surveyed 473 ASHAs and 447 RMPs in six districts of Uttar Pradesh. We assessed knowledge and skills using face-to-face interviews and video vignettes, respectively, about key signs of both conditions. The 'know-can' gap corresponds to absent skills among FLWs with correct knowledge. We used logistic regression to identify the correlates of knowledge and skills.FLWs' correct knowledge ranged from 23% to 48% for dehydration signs and 27% to 37% for pneumonia signs. Their skills ranged from 3% to 42% for dehydration and 3% to 18% for pneumonia. There was a significant 'know-can' gap in all the signs, except 'sunken eyes'. Training and supervisory support was associated with better knowledge and skills for diarrhoea with dehydration, but only better knowledge for pneumonia.FLWs are crucial to the Indian health system, and high-quality FLW services are necessary for continued progress against under-five deaths. The gap between FLWs' knowledge and skills warrants immediate attention. In particular, our results suggest that knowledge-focused trainings are insufficient for FLWs to convert knowledge into appropriate assessment skills.En Inde, les travailleurs de première ligne (TPL) - activistes de la santé sociale accrédités par le public (ASSAP) et prestataires médicaux ruraux privés (PMRP) - sont importants pour la détection et le traitement précoces de la diarrhée et de la pneumonie infantiles. Cette étude transversale vise à mesurer les connaissances et les compétences, et l'écart entre les deux (écart ''savoir-pouvoir''), en ce qui concerne l'évaluation de la diarrhée infantile avec déshydratation et la pneumonie chez les TPL et à explorer les facteurs qui leur sont associés. MÉTHODES: Nous avons mené une enquête sur 473 ASSAP et 447 PMRP dans six districts de l'Uttar Pradesh. Nous avons évalué les connaissances et les compétences à l'aide d'entretiens de face à face et de vignettes vidéo, respectivement, sur les signes clés des deux conditions. L'écart «savoir-pouvoir» correspond à des compétences absentes parmi les TPL ayant des connaissances correctes. Nous avons utilisé la régression logistique pour identifier les corrélats des connaissances et des compétences. RÉSULTATS: Les connaissances correctes des TPL variaient de 23% à 48% pour les signes de déshydratation, 27% à 37% pour les signes de pneumonie. Leurs compétences variaient de 3% à 42% pour la déshydratation et de 3% à 18% pour la pneumonie. Il y avait un écart important dans le «savoir-pouvoir» pour tous les signes, à l'exception des «yeux enfoncés». La formation et le soutien à la supervision étaient associés à de meilleures connaissances et compétences pour la diarrhée avec déshydratation, mais seulement à de meilleures connaissances pour la pneumonie.Les TPL sont cruciaux pour le système de santé indien, et des services de TPL de haute qualité sont nécessaires pour continuer à lutter contre les décès d'enfants de moins de cinq ans. L'écart entre les connaissances et les compétences des TPL mérite une attention immédiate. En particulier, nos résultats suggèrent que les formations axées sur les connaissances sont insuffisantes pour que les TPL convertissent les connaissances en compétences d'évaluation appropriées.
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- 2020
19. Sewage sludge as an alternate energy
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Himadri Tanaya Behera, Abhik Mojumdar, and Lopamudra Ray
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- 2022
20. Purification And Characterization Of Chitooligosaccharides Produced By Microbial Degradation Of Colloidal Chitin By Novel Streptomyces chilikensis RC1830
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Abhik Mojumdar, Behera, Himadri Tanaya, Yoo, Hee-Jin, Duck-Hyun Kim, Park, Ji-Won, Park, Su-Jin, Choi, Jung-Hoon, Lopamudra Ray, and Cho, Kun
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- 2022
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21. Contributors
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K.S. Anantharaju, Ali Anwar, S. Aravindan, Tess Astatkie, Mathew S Baite, Khosro Balilashaki, Himadri Tanaya Behera, Lopamudra Behera, L. Bhanu, Krishna Bharwad, B. Cayalvizhi, Akshita Champaneria, Eduardo Jose Azevedo Correa, Smrutiranjan Das, Tuyelee Das, Diptanu Datta, Zahra Dehghanian, Abhijit Dey, Pushpendra Kumar Dhakad, Neimar de Freitas Duarte, Shubham Dubey, Saraí Esparza-Reynoso, K. Gangadhar, Niharika Ghoghari, Sujit Ghosh, Bisweswar Gorain, Pratishtha Gupta, Khashayar Habibi, S. Harish, Rupak Jena, Priyanka Jha, Jayandra Kumar Johri, Naveen Chandra Joshi, S.R. Joshi, U. Keerthana, Shivani Khatri, Isha Kohli, Praveen Kona, Tulasi Korra, Sumit Kumar, Vipin Kumar, Vijay Kumar, Behanm Asgari Lajayer, P. Kiruthika Lakshmi, Jesús Salvador López-Bucio, José López-Bucio, S. Meenakshi, Debasis Mitra, Abhik Mojumdar, Sunil S. More, Veena S. More, A. Muthu Kumar, Ajay Nair, Samapika Nandy, R. Naveen Kumar, Christiane Abreu Oliveira Paiva, Marcela Claudia Pagano, Devendra Kumar Pandey, P. Panneerselvam, Joginder Singh Panwar, C. Parameswaran, Manoj Parihar, Srijita Paul, Ramón Pelagio-Flores, S.R. Prabhukarthikeyan, S. Raghu, Shalini Rajkumar, Suryansh Rajput, Kirti Rani, Rupa Rani, Archana S. Rao, P.C. Rath, Lopamudra Ray, Kiran K. Reddy, Monire Mones Sardrodi, Preeti Sengupta, Efath Shahnaz, Shilpi Sharma, Deepali Shukla, Piyush Shukla, A.L. Singh, Poonam C. Singh, Prashant Kumar Singh, Bana Sravani, Ashmita Tandon, Stevenson Thabah, Ajit Varma, Ambarish S. Vidyarthi, M.K. Yadav, and Manoj K. Yadav
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- 2022
22. Scale-Up of Engineering Strain for Industrial Applications
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Lopamudra Ray and Vishakha Raina
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- 2022
23. List of contributors
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Mir Sahidul Ali, S. Aruna Sharmili, Arunima Bhattacharjee, Joyani Bhattacharjee, Ankurita Bhowmik, Debasmita Chakraborty, K. Chandrasekhar, Dipankar Chattopadhyay, Ashwini Chauhan, Jaya Chawla, Ankita Dey, Bandita Dutta, Subhasish Dutta, Tushar Kanti Dutta, Saksham Garg, Sougata Ghosh, Azaruddin V. Gohil, Mayakkannan Gopal, Sangita Jana, Slipa Kanungo, Bhavtosh A. Kikani, Dibyajit Lahiri, Avinash Marwal, Mukesh Meena, Moupriya Nag, Jonathan Tersur Orasugh, Anjana Pandey, Farzin Parabia, Hiren K. Patel, Ritesh Pattnaik, Lopamudra Ray, Rina Rani Ray, Nahid Rehman, Jayesh Ruparelia, Shruthi Sampatkumar, Jayashree Shanmugam, Apoorva Sharma, Surbhi Sharma, Anupama Shrivastav, Meenakshi Singh, Puneet Kumar Singh, Sweta Singh, Kanishka Srivastava, Shobana Sugumar, Prashant Swapnil, Pragati Thakur, Nensi K. Thumar, Raymond J. Turner, Smita Rastogi Verma, and Saanya Yadav
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- 2022
24. Contributors
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Ovaid Akhtar, null Aniruddha Mukhopadhyay, Moh Sajid Ansari, Neeraj Atray, Sakshi Awasthi, Gopal Samy Balakrishnan, Soumya Banerjee, Megha Bansal, Jorge Bedia, Himadri Tanaya Behera, Carolina Belver, C. Ben Youssef, Pritha Bhattacharjee, Aman K. Bhonsle, Adrija Bose, Rupa Chaudhuri, A. Córdova Lizama, Praveen Dahiya, Papita Das, Shreeja Datta, Khac-Uan Do, Subhasish Dutta, Bhavika Garua, Krishnendu Ghosh, José C. Góis, Luciano A. Gomes, Anuksha Gulati, Mohammad Haris, G. Hernández-Martínez, Touseef Hussain, Venkatalakshmi Jakka, Jeyakanthan Jeyraman, Harbans Kaur Kehri, Abrar Ahmad Khan, Amir Khan, Anoar Ali Khan, Jaya Lakkakula, Ritika Luthra, Tero Luukkonen, Anjali Mandal, Abhik Mojumdar, Madhumanti Mondal, Dipti Mundhe, Raghvendra Paratap Narayan, T. Nguyen-Hong Nguy, Dheeraj Pandey, Chitra Jeyaraj Pandian, Jyoti Porwal, Margarida J. Quina, Lopamudra Ray, Arpita Roy, J.E. Ruiz Espinoza, Andreia F. Santos, Shubhalakshmi Sengupta, Tanusree Sengupta, Jai Gopal Sharma, Archana Singh, Neetu Singh, Surbhi Sinha, Rajendren Sironmani, Varsha Sonkamble, Atirah Tauseef, Neha Tiwari, Nilesh Wagh, R. Yañez Palma, Adeyinka S. Yusuff, A. Zepeda Pedreguera, Ifra Zoomi, and Shidra Zuby
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- 2022
25. Microbe-based plant biostimulants and their formulations for growth promotion and stress tolerance in plants
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Lopamudra Ray, Abhik Mojumdar, Himadri Tanaya Behera, and Smrutiranjan Das
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Stress (mechanics) ,business.industry ,Growth promotion ,Biology ,business ,Biotechnology - Published
- 2022
26. List of contributors
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Uday Pratap Azad, A.C. Bastos, Himadri Tanaya Behera, Punyasloke Bhadury, M.B. Binish, P. Binu, L. Breton-Deval, J.K. Bwapwa, Jaya Chakraborty, Sukalyan Chakraborty, Shalini Chandel, Pranjal Chandra, Ram Chandra, Shreosi Chatterjee, Subhankar Chatterjee, Punarbasu Chaudhuri, Ashvini Chauhan, Khushboo Choudhary, Santanu Chowdhury, Surajit Das, Debashis Dash, Deepika Devadarshini, Tushar Dhamale, null Divya, Nelson Duran, Bobby Edwards III, Paul H. Fallgren, S. Fragoeiro, Aniket Gade, Priyanka Gehlot, Anwesha Ghosh, V.G. Gopikrishna, S. Gouma, A. Guevara-García, Indarchand Gupta, Pratishtha Gupta, Tony Gutierrez, Soumya Haldar, Avinash Ingle, Rajneesh Jaswal, Song Jin, K. Juarez, Adarsh Kumar, Vipin Kumar, Swetambari Kumari, Neelam Kungwani, P. Lara, N. Magan, Rishi Mahajan, Supratim Mahapatra, Uma Mahto, Raya Majumdar, Luis Rafael Martínez-Córdova, Marcel Martínez-Porchas, Bibhuti Bhusan Mishra, Mahesh Mohan, Balaram Mohapatra, Swati Mohapatra, Abhik Mojumdar, Christina Nikolova, Krishna Palit, S. Panigrahi, Nidhi Pareek, Sunil Parthasarathy, Kristofer G. Paso, Neha P. Patel, Ashish Pathak, Swayamsidha Pati, Swati Pattnaik, Prashant S. Phale, Marco Antonio Porchas-Cornejo, Monika Priyadarshanee, Hemant J. Purohit, Asifa Qureshi, Mahendra Rai, Rupa Rani, Sonalin Rath, Lopamudra Ray, Arijit Reeves, Glen Ricardo Robles-Porchas, D. Rubio-Noguez, Annapoorni Lakshman Sagar, Braja Kishor Saha, Deviprasad Samantaray, Amedea B. Seabra, Wasim Akram Shaikh, Nagaraj P. Shetti, M.E. Shuaib, Sudhir K. Shukla, Dayananda Siddavattam, Ankur Singh, Ananya Srivastava, T. Subba Rao, Ksheerabdi Tanaya, E. Tovar-Sanchez, null Vandana, Francisco Vargas-Albores, P. Velraj, Shalini Verma, Vivekanand Vivekanand, and Prerna J. Yesankar
- Published
- 2022
27. Contributors
- Author
-
Md. Afjal Ahmad, Ramesh Alluri, Stênio Nunes Alves, Himadri Tanaya Behera, Alok Bharadwaj, Khushbo Bhardwaj, Ashok Bhattacharyya, Sundaresan Bhavaniramya, Rafael Dorighello Cadamuro, Surabhi Chaturvedi, Pulkit Chawla, Mairon Cesar Coimbra, Eduardo José Azevedo Corrêa, Santhosha Dasarapu, Leonardo Henrique França de Lima, Marcelo de Souza Lauretto, Shrestha Debnath, Abhijit Dey, Gislaine Fongaro, Palash Ghorai, Dipankar Ghosh, Sukanya Gogoi, Th Indrama, Sérgio Luiz Alves Júnior, Taraka Sunil Kumar Karumuri, Harpreet Kaur, Sanchita Kulshrestha, Ananth Kurella, V. Mageshwaran, M.K. Mahatama, Doris Sobral Marques Souza, Snehashis Mishra, Mohammad Reza Moosavi, Samapika Nandy, Adelaide Cássia Nardocci, null Neemisha, M. Nikhil Raj, Devendra Kumar Pandey, K. Pandiyan, Joginder Singh Panwar, Prerana Parihar, Amit Paschapur, Jagdish Kumar Patidar, Pravin Prakash, Asha Singh Rajavat, Neeraj Rani, Lopamudra Ray, Maria Tereza Pepe Razzzolini, Paula Rogovski, Vidya Sabbani, Bandana Saikia, Ipsita Samal, Seema Sangwan, Maria Inês Zanoli Sato, Ajit Kumar Savani, Beatriz Pereira Savi, Pankaj Sharma, A.L. Singh, H.B. Singh, Puneet Singh, Purnima Singh, Sushila Singh, Sushmita Singh, A.R.N.S. Subbanna, J.C. Tarafdar, Onkar Nath Tiwari, Helen Treichel, Sneha Tripathi, Champa keya Tudu, Ramar Vanajothi, Vanitha Kondi, I. Venkatesh, Aman Verma, and Selvaraju Vishnupriya
- Published
- 2022
28. Biofertilization of biogas digestates: An insight on nutrient management, soil microbial diversity and greenhouse gas emission
- Author
-
Puneet Singh, Himadri Tanaya Behera, Snehashis Mishra, and Lopamudra Ray
- Published
- 2022
29. Biology, genetic aspects and oxidative stress response of actinobacteria and strategies for bioremediation of toxic metals
- Author
-
Himadri Tanaya Behera, Abhik Mojumdar, and Lopamudra Ray
- Published
- 2022
30. Polyhydroxyalkanoates: Resources, Demands and Sustainability
- Author
-
Lopamudra Ray, Abhik Mojumdar, Binita Bhattacharyya, Vishakha Raina, and Himadri Tanaya Behera
- Subjects
Natural resource economics ,Sustainability ,Business ,Polyhydroxyalkanoates - Published
- 2019
31. Eco‐Friendly and Economical Method for Detoxification of Pesticides by Microbes
- Author
-
Abhik Mojumdar, Anjani Kumar Upadhyay, Lopamudra Ray, and Vishakha Raina
- Subjects
Environmental chemistry ,Bioaccumulation ,Detoxification ,Environmental science ,Pesticide ,Soil contamination ,Environmentally friendly - Published
- 2019
32. Rheinheimera pleomorphica sp. nov., a Novel Alkali-Tolerant Bacteria Isolated from Chilika Lake, India
- Author
-
Lopamudra Ray, Ananta N Panda, Samir R. Mishra, and Vishakha Raina
- Subjects
DNA, Bacterial ,Sequence analysis ,India ,Biology ,Chromatiaceae ,Applied Microbiology and Biotechnology ,Microbiology ,Genome ,03 medical and health sciences ,Phylogenetics ,RNA, Ribosomal, 16S ,Phylogeny ,030304 developmental biology ,Genetics ,Whole genome sequencing ,Base Composition ,0303 health sciences ,Phylogenetic tree ,030306 microbiology ,Sequence Analysis, DNA ,General Medicine ,Ribosomal RNA ,16S ribosomal RNA ,Bacterial Typing Techniques ,Lakes ,Multilocus sequence typing ,Multilocus Sequence Typing - Abstract
A novel Gram-negative gamma-proteobacterium, non-sporulating motile, rod or coccus-shaped bacterium designated as strain PKS7T was isolated from a sediment sample collected from Chilika Lake, Odisha, India and characterized taxonomically using a polyphasic approach. The major quinone was Q8 and major cellular fatty acids were C16:0, C17:0, C15:1w8c, C17:1w8c, C12:03-OH. The chemotaxonomic features confirmed the isolate to be a member of genus Rheinheimera. 16SrRNA gene sequence of strain PKS7T was closest in similarity to R. aquimaris SW-353T (99.36% identity), R. muenzenbergensis E49T (98.63%), R. nanhaiensis E407-8T (98.35%), R. japonica KMM 9513T (98.35%) and R. baltica DSM-14885T (98.08%). The 16S rRNA gene sequence-based phylogenetic analysis and sequence similarity between the isolated strain and type strains also revealed its affiliation to genus Rheinheimera. DNA–DNA relatedness with closest type strain R. aquimaris SW-353T was 25.0% (±3.40) and in silico DDH showed values in the range of 17.7–37.1% with the type strains of the genus Rheinheimera for which whole genome sequence are available. Strain PKS7T was also distinguished by a multi-locus sequence analysis (MLST) by alingning gyrB gene sequences of the closest type strains of Rheinheimera. The draft genome of strain PKS7T contained 32 contigs of total size 3,963,569 bp comprising of 3763 predicted coding sequences with a G + C content of 50.7 mol%. Comparision of phenotypic and genotypic data with its closest neighbours and closely related species confirm the strain PKS7T to be recognised as a novel species within the genus Rheinheimera, for which the name Rheinheimera pleomorphica sp. nov. is proposed. The type strain is PKS7T (= KCTC 42365 = JCM 30460).
- Published
- 2019
33. Polyhydroxyalkanoate Recovery From Newly Screened Bacillus Sp. LPPI-81 Using Various Methods of Extraction From Loktak Lake Sediment Sample
- Author
-
Seid Mohammed Ebu and Lopamudra Ray
- Subjects
Chromatography ,Chemistry ,Extraction (chemistry) ,Sediment ,Bacillus sp ,Sample (graphics) ,Polyhydroxyalkanoates - Abstract
Nowadays the conventional plastic wastes are very challenging to environments and its production cost also creates an economic crisis due to petrochemical-based plastic. In order to solve this problem, the current studies were aimed at screening and characterizing these PHA producing isolates and evaluating the suitability of some carbon source for newly screened PHA producing isolates. Some carbon sources such as D-fructose, glucose, molasses, D-ribose and sucrose were evaluated for PHA production. Data were analyzed using SPSS version 20. The 16SrRNA gene sequence of these isolates was performed. This newly isolated taxa was related to Bacillus species. It was designed as Bacillus sp. LPPI-18 and affiliated Bacillus cereus ATCC 14577T (AE01687) (99.10%). Paenibacillus sp. 172 (AF273740.1) was used as an out-group. Bacillus sp. LPPI-18 is a gram-positive, rod-shaped, endospore former, and citrate test positive. This isolate showed positive for amylase, catalase, pectinase, and protease test. They produced intracellular PHA granules when this isolate was stained with Sudan Black B (SBB) and Nile Blue A (NBA) preliminary and specific staining dyes, respectively. Both Temperature and pH used to affect PHA productivity. Bacteria are able to reserve PHA in the form of granules during stress conditions. This isolate produces only when supplied with carbon sources. More PHA contents (PCs) were obtained from glucose, molasses, and D-fructose. In this regard, the maximum mean value of PC was obtained from glucose (40.55±0.7%) and the minimum was obtained from D-Ribose (12.4±1.4%). Great variations (p≤0.05) of PCs were observed among glucose & sucrose, molasses & sucrose and D-fructose & sucrose carbon sources for PHA productivity (PP) of Cell Dry Weight (CDW) g/L. After extraction, PHA film was produced for this typical isolate using glucose as a sole carbon source. Fourier transform infrared spectrum was performed for this isolate and showed the feature of polyester at 1719.64 to 1721.16 wavelength for these extracted samples. The peak of fingerprinting (band of carboxylic acid group) at this wave-length is a characteristic feature of PHB and corresponds to the ester functional group (C=O).
- Published
- 2021
34. Molecular, biochemical, and comparative genome analysis of a rhizobacterial strain Klebsiella Sp. KBG6.2 imparting salt stress tolerance to Oryza sativa L
- Author
-
Berhanu Girma, Ananta N. Panda, Pamela Chanda Roy, Lopamudra Ray, Sasmita Mohanty, and Gopal Chowdhary
- Subjects
Plant Science ,Agronomy and Crop Science ,Ecology, Evolution, Behavior and Systematics - Published
- 2022
35. Draft genome sequence and potential identification of a biosurfactant from Brevibacterium casei strain LS14 an isolate from fresh water Loktak Lake
- Author
-
Tanmaya Nayak, Vishakha Raina, Vipin Gupta, Lopamudra Ray, Khushbu Kumari, Dinabandhu Sahoo, Ananta N Panda, and Sudhanshu K Gouda
- Subjects
Whole genome sequencing ,Comparative genomics ,Sequence analysis ,Environmental Science (miscellaneous) ,Agricultural and Biological Sciences (miscellaneous) ,Genome ,chemistry.chemical_compound ,Biochemistry ,chemistry ,Gene cluster ,Brevibacterium casei ,Surfactin ,GC-content ,Biotechnology - Abstract
This study reports the whole-genome sequencing and sequence analysis of a bacterial isolate Brevibacterium casei strain LS14, isolated from Loktak Lake, Imphal, India. The de novo assembled genome reported in this paper featured a size of 3,809,532 bp, has GC content of 68% and contains 3602 genomic features, including 3551 protein-coding genes, 46 tRNA and 5rRNA. A biosurfactant biosynthesis gene cluster in the genome of the isolated strain was identified using AntiSMASH online tool V3.0.5 and KAAS (KEGG Automatic Annotation Server). The presence of biosurfactant was demonstrated by drop collapse, oil displacement and emulsification index. Subsequent chemical characterization using FTIR and LC–MS analyses revealed surfactin and terpene containing biosurfactant moieties. Also, the presence of genes involved in terpenoid synthesis pathway in the genome sequence may account for biosurfactant terpenoid backbone, but genes for later-stage conversion of terpenoid to biosurfactant were not ascertained.
- Published
- 2021
36. Cell Phone Counseling Improves Retention of Mothers With HIV Infection in Care and Infant HIV Testing in Kisumu, Kenya: A Randomized Controlled Study
- Author
-
Jerry Okal, James K. Matheka, Sam Kalibala, Avina Sarna, Lopamudra Ray Saraswati, Roopal Jyoti Singh, Danmark Owuor, and Nancy R. Reynolds
- Subjects
Adult ,Counseling ,Postnatal Care ,medicine.medical_specialty ,Maternal-Child Health Services ,Anti-HIV Agents ,Mothers ,HIV Infections ,Logistic regression ,Medication Adherence ,law.invention ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,Pregnancy ,law ,Odds Ratio ,Prevalence ,medicine ,Humans ,030212 general & internal medicine ,Lost to follow-up ,Young adult ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics ,Infant, Newborn ,Attendance ,virus diseases ,Infant ,Original Articles ,General Medicine ,Odds ratio ,Patient Acceptance of Health Care ,medicine.disease ,Kenya ,Infectious Disease Transmission, Vertical ,Telemedicine ,Pregnancy Complications ,Logistic Models ,Female ,Lost to Follow-Up ,business ,Cell Phone - Abstract
Tailored, one-on-one counseling delivered via cell phone was very effective in retaining mothers with HIV in care and in promoting infant HIV testing and antenatal and postnatal care attendance. The highest risk of loss to follow-up among women with HIV accessing PMTCT services was prior to delivery and then after infant HIV testing at 6 weeks. Challenges include continued limited access to cell phones, difficulty with reaching participants on the phone, and poor adherence to antiretroviral therapy for a substantial percentage of the population., Background: We evaluated the effectiveness of a cell phone counseling intervention to promote retention in care and HIV testing of infants among women with HIV accessing prevention of mother-to-child services in Kisumu, Kenya. Methods: Between May 2013 and September 2015, we recruited 404 pregnant women with HIV who were between 14 and 36 weeks of gestation and randomly assigned them to the intervention (n=207) or control arm (n=197). Retention was assessed at delivery and at 6 and 14 weeks postpartum. We also measured uptake of infant HIV testing. The intervention comprised a fixed protocol of counselor-delivered phone calls to provide one-to-one need-based support. The number of calls made varied depending on when participants presented for antenatal care services; the maximum number was 42. The control group received routine care. We evaluated retention at 3 time points using the complementary log-log regression model taking into account factors associated with retention and loss to follow-up time. We calculated the incidence rate for HIV transmission among infants and used binary logistic regression to identify predictors of HIV infection among infants. Results: Participants attended on average 63% of the required number of counseling calls during the study period. Retention was higher in the intervention arm than the control arm at delivery (95.2% vs. 77.7%, respectively); 6 weeks postpartum (93.9% vs. 72.9%, respectively); and 14 weeks postpartum (83.3% vs. 66.5%, respectively) (P90%, used to assess adherence to ART, was associated with lower odds of a positive HIV test among infants (adjusted odds ratio=0.20; 95% CI=0.04, 0.99). Attendance at antenatal and postnatal care visits was higher among participants in the intervention arm than the control arm. Conclusions: The one-on-one tailored counseling delivered via cell phone was effective in retaining mothers with HIV infection in care and promoting uptake of infant HIV testing and antenatal and postnatal care services. Phone counseling offers a practical approach to reach and retain pregnant women with HIV infection and postpartum mothers in care, but greater emphasis on collection of medications and adherence is required.
- Published
- 2019
37. Environmental impact assessment of wastewater based biorefinery for the recovery of energy and valuable bio-based chemicals in a circular bioeconomy
- Author
-
Lopamudra Ray, Puneet Kumar Singh, Ritesh Pattnaik, Tapan Kumar Adhya, and Snehasish Mishra
- Subjects
Anaerobic digestion ,education.field_of_study ,Waste treatment ,Waste management ,Wastewater ,Circular economy ,Greenhouse gas ,Population ,Environmental science ,Biorefinery ,education ,Incineration - Abstract
Ever-growing human population, their need for food, energy, and water along with various deadly pollutants are the major threat to the mankind. Hence, there is a need to develop sustainable technologies to provide constant supply of food and energy to enable a circular economy. Wastes in developing countries, if properly managed, can be potential source of energy, recycled materials, and revenue. For waste treatment, technologies such as fermentation, anaerobic digestion (AD), pyrolysis, incineration, and gasification can be used. However, selection of the right technology and proper process will depend on the type of waste, it’s generation, and the desired economy of scale. Hence, there is a need to develop an integrated biorefinery approach so that the waste can be treated to recover energy, produce various value-added products, and reduce greenhouse gases for a sustainable environment. Global availability of freshwater is reducing alarmingly. Majority of the freshwater is used for human consumption and, to a great extent, for industry and agriculture. However, all such anthropogenic activities lead to the generation of wastewater in large quantities that need to be recycled effectively to reduce dependence on freshwater. Biorefineries based on wastewater can play a great role as has been recorded in different parts of the world. This will generate closing the gap in water cycle, recovery of energy and valuable biochemicals, new business opportunities, reduction in greenhouse gases, saving natural resources which eventually will lead to development of a sustainable industrial ecosystem, and establishment of a circular bioeconomy.
- Published
- 2021
38. Contributors
- Author
-
Tapan Kumar Adhya, Dinesh Chand Agrawal, Carlos Ariel Cardona Alzate, Sundaram Arvindnarayan, Mukesh Kumar Awasthi, Sanjeev Kumar Awasthi, Amit H. Batghare, Thallada Bhaskar, Neha Bhatt, Francesco Bianco, Emilia den Boer, Jan den Boer, Walter José Martínez Burgos, Xuan-Thanh Bui, Júlio César de Carvalho, Eulogio Castro, Matheus Cavali, Jo-Shu Chang, Hongyu Chen, Brigitte Sthepani Orozco Colonia, María del Mar Contreras, Raquel de Freitas Dias Milão, Ofélia de Queiroz Fernandes Araújo, Miguel Desmarais, Jeyaprakash Dharmaraja, Kim Valladares Diestra, Yumin Duan, Vincenzo Forino, Minerva García-Vargas, Andrés Felipe Camargo Guarnizo, null Hemansi, Jose Gnanaleela Aswin Jeno, Susan Grace Karp, Doris Kraljić, Bhavya B Krishna, Ramesh Chander Kuhad, Gaurav Kumar, Gopalakrishnan Kumar, Antonio Lama-Muñoz, Luiz Alberto Junior Letti, Tao Liu, Adriane Bianchi Pedroni Medeiros, José Luiz de Medeiros, Snehasish Mishra, Bishwambhar Mishra, Vijayanand S. Moholkar, Velusamy Mozhiarasi, Sandeep Narayan Mudliar, Velmurugan Nagabalaji, Senthil Nagappan, Ekambaram Nakkeeran, Santiago Pacheco-Ruiz, Ashok Pandey, Ritesh Pattnaik, Emil Petre, Marco Race, Lopamudra Ray, Xiuna Ren, Eldon R. Rene, Sara Piedrahita Rodríguez, Cristine Rodrigues, Inmaculada Romero, Juan Miguel Romero-García, Sreevathsan S, Jitendra Kumar Saini, Dan Selişteanu, Georgeio Semaan, Sutha Shobana, Puneet K. Singh, Surender Singh, Joyce Guerios Wanderlei Siqueira, Carlos Ricardo Soccol, Shanmugham Venkatachalam Srinivasan, Rengasamy Suthanthararajan, Mohammad J. Taherzadeh, Luis Alberto Zevallos Torres, Luciana Porto de Souza Vandenberghe, Sunita Varjani, Ravichandran Viveka, Adenise Lorenci Woiciechowski, Rajasri Yadavalli, Siming You, and Zengqiang Zhang
- Published
- 2021
39. Microbial Polysaccharides with Potential Industrial Applications: Diversity, Synthesis, and Their Applications
- Author
-
Lopamudra Ray, Himadri Tanaya Behera, Abhik Mojumdar, and Chiranjib Mohapatra
- Subjects
chemistry.chemical_classification ,chemistry ,Microbial polysaccharides ,Biochemical engineering ,Polysaccharide - Abstract
Polysaccharides are nontoxic, biodegradable, and natural carbohydrate polymers virtually produced by almost all microbes, covering the surface of the cell and serve as the intracellular energy stores, and play a vital aspect in many biological pathways such as response to the infection, signal transduction, adhesion, and acts as a buffer against changing environments. They are mostly present as extracellular capsules, slime creations, or sheaths. Bioactive polysaccharides were proven to show many immune modulatory and health-promoting effects in diseases like cancer and some inflammatory diseases. Thus, substantial research has been carried out on revealing the mechanism behind the biological activity by structural and functional analysis. Apart from their applications in the health sectors, these polysaccharides have huge pertinence in the food, cosmetic, pharmaceutical industries as thickeners, probiotics, bioadhesives, and gelling agents. In environmental sectors, they are used as biosorbent and bioflocculant. In this chapter, several production processes of EPSs using a cost-effective biomass, commercial applications of the EPSs, and general mechanisms of EPS production are briefly described.
- Published
- 2021
40. Microbial Pigments: Secondary Metabolites with Multifaceted Roles
- Author
-
Lopamudra Ray, Himadri Tanaya Behera, Suchismita Nivedita, and Abhik Mojumdar
- Subjects
chemistry.chemical_classification ,Pigment ,Chemistry ,visual_art ,Biological property ,Microorganism ,visual_art.visual_art_medium ,sense organs ,Food science ,Antimicrobial ,Carotenoid ,Violacein - Abstract
Pigments are compounds capable of absorbing light and are responsible for displaying a specific color. Several ores, insects, plants, microbes are the source of the natural pigments. However, microorganisms have enormous potential in producing pigments due to its stability, availability, productivity, easy downstream processing, and yield. Pigments like melanins, quinines melanins, flavins, violacein, monascins, and carotenoids have been produced by microorganisms. Microbial pigments have gained more interest in present research not just due to their utilization as colorants in industries like food, plastic, textile, paint, printing, and paper, but it also possess several biological properties such as antimicrobial, antioxidant, anticancer, and various other bio-pharmacological activities that have been discussed in this chapter. This chapter will lead to the exploration of microorganisms producing pigments, their application in various fields as well as their ultimatums, and future prospective for various applications.
- Published
- 2021
41. Mushroom Mycelia-Based Material: An Environmental Friendly Alternative to Synthetic Packaging
- Author
-
Lopamudra Ray, Abhik Mojumdar, and Himadri Tanaya Behera
- Subjects
Mushroom ,Waste management ,Hazardous waste ,Circular economy ,fungi ,Environmental science ,Substrate (printing) ,Raw material ,Environmentally friendly ,Non-renewable resource ,Mycelium - Abstract
In the circular economy, reduction of the vigorous usages of nonrenewable resources is becoming the leading scenario. Fungal mycelium is the vegetative part of fungus consisting of a number of filamentous fibers that extend out of the fungus and is considered to be natural, fast growing, safe, and renewable. The ability to form self-assembling bonds helps them to grow quickly on biological and agricultural wastes and produce miles of thin fibers which bind to the substrate to form a strong biodegradable material and can easily be shaped for the production of packaging materials, architecture, and various new designed objects. With the benefit of cost-effective raw materials and sustainable substitute to polystyrene like hazardous synthetic materials, this mycelia-based material is becoming the material of choice. This chapter reviews the present scenario of technology-based mushroom cultivation using wastes generated from the agricultural industries and also focuses on a variety of utilizations as an alternative replacement for synthetic polystyrene.
- Published
- 2021
42. Draft genome sequence and potential identification of a biosurfactant from
- Author
-
Khushbu, Kumari, Sudhanshu K, Gouda, Ananta N, Panda, Lopamudra, Ray, Dinabandhu, Sahoo, Tanmaya, Nayak, Vipin, Gupta, and Vishakha, Raina
- Subjects
Original Article - Abstract
This study reports the whole-genome sequencing and sequence analysis of a bacterial isolate Brevibacterium casei strain LS14, isolated from Loktak Lake, Imphal, India. The de novo assembled genome reported in this paper featured a size of 3,809,532 bp, has GC content of 68% and contains 3602 genomic features, including 3551 protein-coding genes, 46 tRNA and 5rRNA. A biosurfactant biosynthesis gene cluster in the genome of the isolated strain was identified using AntiSMASH online tool V3.0.5 and KAAS (KEGG Automatic Annotation Server). The presence of biosurfactant was demonstrated by drop collapse, oil displacement and emulsification index. Subsequent chemical characterization using FTIR and LC–MS analyses revealed surfactin and terpene containing biosurfactant moieties. Also, the presence of genes involved in terpenoid synthesis pathway in the genome sequence may account for biosurfactant terpenoid backbone, but genes for later-stage conversion of terpenoid to biosurfactant were not ascertained. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13205-021-02867-9.
- Published
- 2020
43. Evaluation of a Potential Antibacterial, Produced by Streptomyces Cinereoruber Sp. Isolated from Chlika lake
- Author
-
Anjani K. Upadhyay, Debasmita Chatterjee, Madhuri Swain, Lopamudra Ray, and Blue Eyes Intelligence Engineering and Sciences Publication(BEIESP)
- Subjects
2277-3878 ,Streptomyces, Antibacterial, Optimization ,100.1/ijrte.B4094079220 - Abstract
Streptomyces, isolated from marine and estuarine habitat have been widely recognized as a potential source of antifungal, anti-tumour, anti-bacterial compounds. In the present study, the antimicrobial agent production potential of a Streptomyces cinereoruber sp was evaluated. The selective isolation of the strain was carried out on starch casein agar. The primary screening of the Streptomyces isolate was done by cross streak method against pathogenic test strains Escherichia.coli MTCC 82, Staphylococcus aureus MTCC 96, Bacillus cereus IP406 and Salmonella typhi MTCC 734 and Micrococcus leuteus and the antimicrobial property against Micrococcus leuteus was confirmed. The secondary screening was carried out by using the culture supernatant against the test strain by agar well diffusion method. The growth and antimicrobial production ability of the strain against Micrococcus leuteus was studied. The antimicrobial agent production was also observed till pH 11 and NaCl concentration 3% (w/v). The partially purified compound showed a peak similar to streptomycin in HPLC. The culture condition for the production of the compound was optimised.
- Published
- 2020
44. Draft Genome Sequence of the Plant Growth-Promoting Rhizobacterium Klebsiella sp. Strain KBG6.2, Imparting Salt Tolerance to Rice
- Author
-
Ananta N Panda, Berhanu Girma, Gopal Chowdhary, Lopamudra Ray, and Sasmita Mohanty
- Subjects
Genetics ,Whole genome sequencing ,Plant growth ,Immunology and Microbiology (miscellaneous) ,Strain (chemistry) ,Genome Sequences ,Klebsiella sp ,RNA ,Biology ,Molecular Biology ,Gene ,Genome - Abstract
Klebsiella sp. strain KBG6.2 is a potential salt-tolerant, plant growth-promoting rhizobacterium isolated from a rice field in Konark, Odisha, India. Here, we report the whole-genome sequencing of Klebsiella sp. strain KBG6.2, which has a 5.038-Mb genome containing 4,867 predicted protein-coding sequences and 79 RNA genes.
- Published
- 2020
45. Energy, nutrient, and water resource recovery from agriculture and aquaculture wastes
- Author
-
Lopamudra Ray and Tapan Kumar Adhya
- Subjects
Nutrient ,Aquaculture ,Wastewater ,business.industry ,Environmental protection ,Agriculture ,World population ,Reuse ,business ,Resource recovery ,Green economy - Abstract
Intense anthropogenic activity and consumerist culture of the global billions generate millions of tons of wastes throughout the world on a day-to-day basis. India with its approximately 1.3 billion people, that is 18% of the world population, also contributes substantially to waste generation and deposition. Although these wastes are rich in nutrients, organic compounds, and energy, they are not properly managed and exploited toward recovery and reuse. Efficient resource recovery and reuse can create sustainable livelihood and also support green economy by reducing waste and improving general environmental health and recovery of cost. Thus there is a need to recycle and reuse the waste produced from various sources in an efficient manner to meet the demand. This chapter elaborates the description of major agriculture and aquaculture wastes in India and focuses primarily on recovery of agriculture and aquaculture wastes for reuse and recycling. Since the amount of waste, particularly wastewater produced in India by agri-aquaculture practices, is huge, various avenues of recycling and eventual reuse have been discussed. Finally the contribution of the resource recovery approach toward bio-based economy has been considered.
- Published
- 2020
46. Contributors
- Author
-
Tapan Kumar Adhya, null Ankush, Robin Bahuguna, J. Rajesh Banu, Mansi Bhatt, Parameswaran Binod, Debajyoti Bose, Avantika Chandra, Hirok Chaudhuri, C.R. Cheeseman, Chuan Chen, Abhijit Dave, G. Saradha Devi, Myilsamy Dineshkumar, Tenzin Dolker, Lucília Domingues, Shane Donatello, Brahm Dutt, Le Fang, Bo Fu, Anand Giri, Edgard Gnansounou, M. Gopinath, M. Gunasekaran, Hongxiao Guo, Pratishtha Gupta, Nidhi Joshi, R. Yukesh Kannah, Keikhosro Karimi, null Kashyap Kumar Dubey, S. Kavitha, Samir Khanal, null Khushboo, Sang-Hyoun Kim, Gopalakrishnan Kumar, Madhava Anil Kumar, N. Manoj Kumar, Vipin Kumar, Duu-Jong Lee, Jiang-Shan Li, Yajie Li, Hongbo Liu, He Liu, M. Estefanía López, Mrinal Kanti Mandal, Sabapathy Manigandan, Michele Michelin, Safoora Mirmohamadsadeghi, Kalpana Mody, P. Mullai, C. Muthukumaran, Ramkumar B. Nair, Ekambaram Nakkeeran, Supriya Pal, Ashok Pandey, Deepak Pant, Chi Sun Poon, K.S. Rajmohan, Rupa Rani, Ravichandran Rathna, Ritika Rawat, Lopamudra Ray, Eldon R. Rene, Crístina M.R. Rocha, Aloia Romaní, Gopalakrishnan Sarojini, Muthulingam Seenuvasan, Virbala Sharma, G. Sharmila, Raveendran Sindhu, V.M. Sivakumar, S. Srinath, José A. Teixeira, Shabnam Thakur, M. Thirumarimurugan, Daniel C.W. Tsang, T.M. Mohamed Usman, Zeba Usmani, S. Vaishnavi, Sunita Varjani, P. Vijay, S. Vishali, Qiming Wang, Xi-Jun Xu, Harshit Yadav, Karuna Yadav, M.K. Yogeswari, and Jie Zhang
- Published
- 2020
47. Association of serum pentraxin 3 and high-sensitivity C-Reactive protein with severity of coronary stenosis
- Author
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SujathaMahadevarao Premnath, SunilKumar Nanda, Lopamudra Ray, MarkChristopher Arokiaraj, and Kandasamy Ravichandran
- Subjects
General Medicine - Published
- 2022
48. Comparison of Lipid Accumulation Product Index with Body Mass Index and Waist Circumference as a Predictor of Metabolic Syndrome in Indian Population
- Author
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Kandasamy Ravichandran, Sunil Kumar Nanda, and Lopamudra Ray
- Subjects
Adult ,Male ,Waist ,Endocrinology, Diabetes and Metabolism ,India ,Physiology ,030209 endocrinology & metabolism ,030204 cardiovascular system & hematology ,Body Mass Index ,03 medical and health sciences ,Sex Factors ,0302 clinical medicine ,Predictive Value of Tests ,Internal Medicine ,Humans ,Medicine ,Prospective Studies ,Prospective cohort study ,Triglycerides ,Aged ,Metabolic Syndrome ,business.industry ,Age Factors ,Case-control study ,Middle Aged ,medicine.disease ,Case-Control Studies ,Predictive value of tests ,Mann–Whitney U test ,Female ,Waist Circumference ,Metabolic syndrome ,Lipid Accumulation Product ,business ,Body mass index - Abstract
Metabolic syndrome (MetS), which confers a high risk for cardiovascular diseases, needs early diagnosis and treatment to reduce morbidity and mortality. Lipid accumulation product index has been reported to be an inexpensive marker of visceral fat and metabolic syndrome. This study aimed to evaluate lipid accumulation product index as a marker for metabolic syndrome in the Indian population where the prevalence of the condition is steadily increasing.A hospital-based, case-control study was conducted with 72 diagnosed cases of metabolic syndrome and 79 control subjects. In all the participants, body mass index (BMI) and lipid accumulation product index were calculated. The difference between cases and controls in BMI, waist circumference (WC), and lipid accumulation product index was assessed by Mann-Whitney U test/unpaired t-test. Associations of BMI, WC, and lipid accumulation product index with metabolic syndrome were compared by multiple logistic regression analysis and receiver operating characteristic analysis.BMI, WC, and lipid accumulation product index were significantly higher in metabolic syndrome (P 0.05). Although all were independently associated with metabolic syndrome, lipid accumulation product index had the highest prediction accuracy. The parameter also had a high area under curve of 0.901 (95% confidence interval 0.85-0.95) and a high sensitivity (76.4%), specificity (91.1%), positive predictive value (88.7%), and negative predictive value (80.9%) for detection of metabolic syndrome.In the Indian population, lipid accumulation product index is a better predictor of metabolic syndrome compared to BMI and WC and should be incorporated in laboratory reports as early, accurate, and inexpensive indicator of metabolic syndrome.
- Published
- 2018
49. Lipid accumulation product index as visceral obesity indicator in psoriasis: A Case–control Study
- Author
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Satyaki Ganguly, Lopamudra Ray, Sheela Kuruvila, Sunil Kumar Nanda, and Kandasamy Ravichandran
- Subjects
obesity ,lipid accumulation product index ,digestive, oral, and skin physiology ,visceral fat ,lcsh:Dermatology ,psoriasis ,lcsh:RL1-803 ,Cardiovascular disease risk ,human activities - Abstract
Background: Psoriasis has well-known associations with individual components of metabolic syndrome such as hypertension, dyslipidemia, insulin resistance, and obesity. Traditional anthropometric measurements of obesity such as waist circumference (WC) and body mass index (BMI) do not differentiate between subcutaneous fat and visceral fat, the latter being associated with cardiovascular risk factors. Lipid accumulation product (LAP) index is a measure of visceral fat and has been found to be a better predictor of cardiovascular risk. However, LAP index has not been well-studied in psoriasis patients. Aims and Objectives: Our objective was to find out if LAP index differs significantly between psoriasis patients and controls and whether LAP index shows a correlation with duration and severity of psoriasis. Materials and Methods: A case–control study was undertaken with 40 chronic plaque psoriasis patients and 42 controls. BMI and LAP index were calculated for all the patients and controls. Psoriasis area severity index (PASI) was calculated for all the psoriasis patients. Mann–Whitney U-test was done for comparing the age, BMI, WC, serum triglyceride, and LAP index between the cases and controls and to compare the LAP index between mild psoriasis and moderate-to-severe psoriasis groups. Spearman's correlation coefficient was used to assess the correlation of LAP index with duration of psoriasis and with PASI. Logistic regression models were done to assess the risk factors in psoriasis. Results: A statistically significant difference was observed between the LAP index of controls (23.79 ± 13.02) and that of psoriasis patients (46.42 ± 27.2). LAP index was significantly higher in the moderate-to-severe psoriasis group as compared to the mild psoriasis group. LAP index was a significant risk factor associated with psoriasis (OR = 1.07; 95% CI: 1.03 – 1.11). Conclusion: Calculation of LAP index in psoriasis patients helps in identification of more individuals at high risk of cardiovascular morbidity than traditional anthropometric measurements of obesity.
- Published
- 2018
50. Optimization of media components for the production of N-acetylchitooligosaccharide from chitin by Streptomyces chilikensis through Taguchi experimental design
- Author
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Anjani Kumar Upadhyay, Himadri Tanaya Behera, Vishakha Raina, and Lopamudra Ray
- Subjects
Microbiology (medical) ,Microorganism ,Oligosaccharides ,Chitin ,Bacterial growth ,Microbiology ,Streptomyces ,03 medical and health sciences ,chemistry.chemical_compound ,Taguchi methods ,Industrial Microbiology ,Glucosamine ,Animals ,Raffinose ,Molecular Biology ,Biotransformation ,030304 developmental biology ,Shellfish ,Waste Products ,0303 health sciences ,Streptomyces chilikensis ,biology ,030306 microbiology ,Pulp and paper industry ,biology.organism_classification ,Culture Media ,chemistry ,Research Design ,Fermentation - Abstract
Optimization of media composition for microbial growth is crucial particularly in industrial processes to obtain the desired end product. The waste from sea food industries includes the non-edible parts of shrimp, crabs and prawns which are rich in chitin as the major cause of pollution in coastal areas. Chitin degradation is carried out chemically. It can be degraded biologically also, particularly using microorganisms resulting in chitooligosaccahrides and the monomer N-acetylglucosamine. N-acetyl glucosamine and related chitooligosaccahrides have various applications such as treatment of cancer and metastasis, treatment of autoimmune reactions, as food supplements and increased plant stress tolerance against salinity and heavy metals. Thus, chitin waste can be efficiently degraded biologically using microorganisms to produce such useful products. Conventional methods such as One factor at a time (OFAT) are more time consuming and costly to address the problem. The current work focuses on the development of an experimental design to ascertain parameters optimized for chitin degradation by a Streptomyces chilikensis to produce various chitooligosaccharides. More than one factor was taken at a time to carry out the experiments and the data were fit into Taguchi Design to determine the contribution of the most important factors responsible for the production of the desired end product that is NAG and other chitooligosaccaharides. Highest NAG production (3741 μM/reaction) was observed in a media that contains 0.5% Raffinose (w/v), 0.5% peptone (w/v), 2.5% NaCl at pH 11.
- Published
- 2019
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