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In this study, we employed a previously developed in vivo assay system to determine whether the flowers and leaves of Syringa vulgaris (S. vulgaris; commonly known as “lilac”) can prevent blood stasis syndrome, known as oketsu in Japanese. This syndrome is considered an important pathology in traditional Chinese and Japanese medicine, and is related to diseases such as peripheral vascular disorders, blood vessel inflammation, and platelet aggregation, whose severities are augmented owing to lipid peroxidation, free radicals, and oxidative stress. The assay system employed in this study monitored the blood flow decrease in the tail vein of mice subjected to sensitization with hen egg white lysozyme. Through bioassay-guided fractionation of different S. vulgaris extracts, five polyphenols were isolated and identified. Among them, quercetine 3-glucoside, quercetin 3-rutinoside, and acteoside were identified as active compounds, as they significantly mitigated blood flow reduction. These findings indicate that the polyphenols obtained from S. vulgaris could be useful for preventing oketsu and improve the quality of life of individuals with disorders and diseases such as gynecopathy, cold sensitivity, poor circulation, allergy, and lifestyle-related diseases.

第31回アストロダイナミクスシンポジウム (2021年7月26-27日. オンライン開催), The 31th Workshop on JAXA Astrodynamics and Flight Mechanics 2021 (July 26-27, 2021. Online Meeting), 著者人数: 11名, 資料番号: SA6000167055, レポート番号: ASTRO-2021-C003

第58回宇宙科学技術連合講演会（2014年11月12日-14日. 長崎ブリックホール), 長崎市, 長崎県, "This paper reports the result of Japan’s operation support for Cygnus missions. Cygnus is the one of cargo transfer vehicles fly to the International Space Station (ISS) and it is developed by Orbital Sciences Corporation, U.S. private company. The first vehicle succeeded as demonstration in September/October 2013 and following 2 missions have been completed successfully for one year. Cygnus utilizes Japan’s proximity communication system (PROX) for its ISS proximity rendezvous operation. Japan’s PROX operation team has supported Cygnus missions.", 資料番号: AC1500093000, レポート番号: JSASS-2014-4731

To assess the capacity of the natural environment for degrading PHB/V, the film-MPN method proposed previously was modified to estimate the numbers of PHB/V degrading microorganisms (degraders) in various environments. The First-Order Reaction (FOR) model was used to determine the appropriate incubation period for the method. Numbers of aerobic PHB/V degraders were estimated in garden soil, paddy field soil, farm soil, river bank soil, infertile garden soil, river water, activated sludge, and seawater by the film-MPN method. Results were compared with those estimated by the clear-zone technique and showed that the film-MPN method was suitable for estimating the numbers of PHB/V degraders in the environments tested. On the other hand, biodegradability of injection molded PHB/V samples was investigated in several kinds of environments. The changes of weight were studied and results showed that biodegradability of PHB/V related to the numbers of PHB/V degraders in similar ecosystem in different regions. In different environments the biodegradability of PHB/V not only related to the number of PHB/V degraders, but also depended on whether there were conditions for the PHB/V degraders to grow and proliferate easily in the environment.

資料番号: AA0047899151