Search

Your search keyword '"Mazzone M"' showing total 86 results
Start Over Author "Mazzone M" Database OpenAIRE
86 results on '"Mazzone M"'

2. An associative account of inferences: The development towards the prototype

Author

Mazzone, M.

Subjects
Reasoning, Association, Consciousness, Inference, Development, inference, Philosophy. Psychology. Religion, association, reasoning, consciousness, development
Abstract

According to a traditional view, inferences are personal-level entities pertaining to the domain of reasons, and therefore they cannot be accounted for in causal terms – specifically, as mere associations. I intend to argue that this is at the very least a drastic simplification, for two reasons. First, the word “association” is polysemous, so we should specify in which of its possible senses an inference is not a mere association. Second, personal-level inferences based on formal rules are only the extreme end of a complex developmental trajectory. As the last decades of research in the field have shown, we should refrain from identifying the entire domain of reasoning with that final stage, which is in fact mostly contingent upon extensive logical training. In this paper, I try to disentangle some major stages in the development of full-fledged (prototypical) inferences, and then to show that all of them – till the final one – can be considered associative in appropriate senses of the word.

Published
2021

3. Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence

Author

Parkash, J, Messina, A, Langlet, F, Cimino, I, Loyens, A, Mazur, D, Gallet, S, Balland, E, Malone, SA, Pralong, F, Cagnoni, G, Schellino, R, De Marchis, S, Mazzone, M, Pasterkamp, RJ, Tamagnone, L, Prevot, V, Giacobini, P, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U1172 Inserm - U837 (JPArc), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Lille Nord de France (COMUE)-Université de Lille, Institut de médecine predictive et de recherche thérapeutique (IMPRT), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Régional de Lutte contre le Cancer Oscar Lambret [Lille] (UNICANCER/Lille), Université Lille Nord de France (COMUE)-UNICANCER-Université Lille Nord de France (COMUE)-UNICANCER-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Faculty of Biology and Medicine [Lausanne, Switzerland], Université de Lausanne (UNIL), Candiolo Cancer Institute [Candiolo, Italie], Università degli studi di Torino (UNITO), Vesalius Research Center [Louvain, Belgique], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Brain Centre Rudolf Magnus [Utrecht], University Medical Center [Utrecht], Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 (JPArc), Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Université de Lille-UNICANCER-Université de Lille-UNICANCER-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Lausanne = University of Lausanne (UNIL), Università degli studi di Torino = University of Turin (UNITO), and Prevot, Vincent

Subjects
endocrine system, Chemistry(all), Ovariectomy, Blotting, Western, Fluorescent Antibody Technique, Enzyme-Linked Immunosorbent Assay, PLEXINC1, Semaphorins, Physics and Astronomy(all), Real-Time Polymerase Chain Reaction, Article, ACTIN, AXON GUIDANCE, Rats, Sprague-Dawley, Mice, Antigens, CD, Image Processing, Computer-Assisted, Journal Article, Animals, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Progesterone, SEMAPHORIN 7A, GENE-EXPRESSION, Analysis of Variance, Science & Technology, Neuronal Plasticity, RECEPTOR, Estradiol, Biochemistry, Genetics and Molecular Biology(all), Research Support, Non-U.S. Gov't, Median Eminence, TGF-BETA, Flow Cytometry, Immunohistochemistry, GNRH NEURONS, Rats, Multidisciplinary Sciences, ESTROUS-CYCLE, HORMONE NERVE-TERMINALS, GONADOTROPIN, GnRH, Science & Technology - Other Topics, RAT, Female, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Settore BIO/17 - ISTOLOGIA, Neuroglia
Abstract

Reproductive competence in mammals depends on the projection of gonadotropin-releasing hormone (GnRH) neurons to the hypothalamic median eminence (ME) and the timely release of GnRH into the hypothalamic–pituitary–gonadal axis. In adult rodents, GnRH neurons and the specialized glial cells named tanycytes periodically undergo cytoskeletal plasticity. However, the mechanisms that regulate this plasticity are still largely unknown. We demonstrate that Semaphorin7A, expressed by tanycytes, plays a dual role, inducing the retraction of GnRH terminals and promoting their ensheathment by tanycytic end feet via the receptors PlexinC1 and Itgb1, respectively. Moreover, Semaphorin7A expression is regulated during the oestrous cycle by the fluctuating levels of gonadal steroids. Genetic invalidation of Semaphorin7A receptors in mice induces neuronal and glial rearrangements in the ME and abolishes normal oestrous cyclicity and fertility. These results show a role for Semaphorin7A signalling in mediating periodic neuroglial remodelling in the adult ME during the ovarian cycle., Reproduction in mammals is dependent on the function of specific neurons that secrete gonadotropin-releasing hormone (GnRH) and project their axons to the median eminence (ME) of the hypothalamus. Here the authors show that Semaphorin7A signaling plays a role in mediating the plasticity of GnRH axon terminals and tanycytes in the ME.

Published
2020
Full Text
View/download PDF

4. The Shape of Art History in the Eyes of the Machine

Author

Ahmed Elgammal, Liu, B., Kim, D., Elhoseiny, M., and Mazzone, M.

Subjects
FOS: Computer and information sciences, Artificial Intelligence (cs.AI), Computer Science - Artificial Intelligence, Computer Vision and Pattern Recognition (cs.CV), Computer Science - Computer Vision and Pattern Recognition, General Medicine
Abstract

How does the machine classify styles in art? And how does it relate to art historians' methods for analyzing style? Several studies showed the ability of the machine to learn and predict styles, such as Renaissance, Baroque, Impressionism, etc., from images of paintings. This implies that the machine can learn an internal representation encoding discriminative features through its visual analysis. However, such a representation is not necessarily interpretable. We conducted a comprehensive study of several of the state-of-the-art convolutional neural networks applied to the task of style classification on 67K images of paintings, and analyzed the learned representation through correlation analysis with concepts derived from art history. Surprisingly, the networks could place the works of art in a smooth temporal arrangement mainly based on learning style labels, without any a priori knowledge of time of creation, the historical time and context of styles, or relations between styles. The learned representations showed that there are a few underlying factors that explain the visual variations of style in art. Some of these factors were found to correlate with style patterns suggested by Heinrich Wölfflin (1846-1945). The learned representations also consistently highlighted certain artists as the extreme distinctive representative of their styles, which quantitatively confirms art historian observations.

Published
2018
Full Text
View/download PDF

5. CAN: Creative Adversarial Networks, Generating 'Art' by Learning About Styles and Deviating from Style Norms

Author

Ahmed Elgammal, Liu, B., Elhoseiny, M., and Mazzone, M.

Subjects
FOS: Computer and information sciences, Artificial Intelligence (cs.AI), Computer Science - Artificial Intelligence
Abstract

We propose a new system for generating art. The system generates art by looking at art and learning about style; and becomes creative by increasing the arousal potential of the generated art by deviating from the learned styles. We build over Generative Adversarial Networks (GAN), which have shown the ability to learn to generate novel images simulating a given distribution. We argue that such networks are limited in their ability to generate creative products in their original design. We propose modifications to its objective to make it capable of generating creative art by maximizing deviation from established styles and minimizing deviation from art distribution. We conducted experiments to compare the response of human subjects to the generated art with their response to art created by artists. The results show that human subjects could not distinguish art generated by the proposed system from art generated by contemporary artists and shown in top art fairs. Human subjects even rated the generated images higher on various scales., Comment: This paper is an extended version of a paper published on the eighth International Conference on Computational Creativity (ICCC), held in Atlanta, GA, June 20th-June 22nd, 2017

Published
2017
Full Text
View/download PDF

7. Design of new reaction conditions for characterization of a mutant thermophilic a-L-fucosidase

Author

Cobucci Ponzano B., Conte F., Mazzone M., MORACCI, Marco, BEDINI, EMILIANO, CORSARO, MARIA MICHELA, ROSSI, MOSE', Cobucci Ponzano, B., Conte, F., Mazzone, M., Bedini, Emiliano, Corsaro, MARIA MICHELA, Rossi, Mose', and Moracci, Marco

Abstract

Glycosynthases are mutant glycosidases, which in the presence of activated glycosides and suitable reaction conditions, synthesize oligosaccharides without hydrolysing them. This feature makes these catalysts promising tools for the large scale synthesis of carbohydrates. However, despite the popularity of the glycosynthetic approach, the number of enzymes effecting glycosynthetic reactions is still limited. We report here on the design of novel reaction conditions for a thermophilic α-l-fucosidase mutant, which might provide a route for the production of novel glycosynthases.

Published
2008

22. Are there communicative intentions?

Author

Mazzone, M. and Campisi, E.

Abstract

Grice in pragmatics and Levelt in psycholinguistics have proposed models of human communication where the starting point of communicative action is an individual intention. This assumption, though, has to face serious objections with regard to the alleged existence of explicit representations of the communicative goals to be pursued. Here evidence is surveyed which shows that in fact speaking may ordinarily be a quite automatic activity prompted by contextual cues and driven by behavioural schemata abstracted away from social regularities. On the one hand, this means that there could exist no intentions in the sense of explicit representations of communicative goals, following from deliberate reasoning and triggering the communicative action. On the other hand, however, there are reasons to allow for a weaker notion of intention than this, according to which communication is an intentional affair, after all. Communicative action is said to be intentional in this weaker sense to the extent that it is subject to a double mechanism of control, with respect both to present-directed and future-directed intentions.

Published
2010

27. Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

Author

Aragones J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, Harten SK, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, and Baes

Published
2008

29. Quality in Emergency Department: a study on 3,285,440 admissions

Author

Sartini, Marina, Cremonesi, P., Tamagno, R., Cristina, MARIA LUISA, Orlando, Paolo, Vandelli, A., Carinci, A., Caruso, A., Grotti, A., Iacovella, A., LA BROCCA, A., Mangioncalda, A., Longanesi, A. M., Susi, B., Barletta, C., Braglia, D., Coen, D., Tazza, D., Gottardi, E., Palego, E., Urbano, E., Bar, F., Bussani, F., DE GIORGI, F., Esposito, F., Fabi, F., Lotti, F., Miglio, F., Moscariello, F., Pertoldi, F., Sardella, F., Tosato, F., Abregal, G., Baldi, G., Carbone, G., Cerqua, G., Giagnorio, G., Pia, G., Piazza, G., Tedesco, G., Sallustio, G. F., Morana, I., Beringheli, L., Jannotti, L., Spinsi, L., Zulli, L., Cavazza, M., DE SIMONE, M., Galletti, M., GIOFFRÈ FLORIO, M., Greco, M., Longoni, M., Luppi, M., Magnani, M., Mazzone, M., Pastorello, M., Pazzaglia, M., Ravaglia, M., Zammataro, M., Zanna, M., Bressan, M. A., Saggese, M. P., GENTILONI SILVERI, N., Scopetta, N., DE MITRI, O., Fantin, O., Boscolo, P., Cancemi, P., DE ANGELIS, P., DI PIETRO, P., Mosca, P., Pacelli, P., Torboli, P., Copetti, R., Fazio, R., Losordo, R., Melandri, R., Papitto, R., Chiaravalle, S., Orlando, S., Sturlese, U., DI GRANDE, A., Narbone, G., Zimmermann, H., Martinelli, L., Clanchini, V., Paternosto, D., Fiorilli, M., DEL PRATO, C., Becheri, M., Lanigra, M., Guerra, G., Sinno, C., Soragna, A., Ferranio, M. P., Bua, V., Capra, R., and Lualdi, E.

Published
2007

30. Quality in emergency departments: a study on 3,285,440 admissions

Author

Sartini, M, Cremonesi, P, Tamagno, R, Cristina, Ml, Orlando, P, Simeu, Group, Vandelli, A, Carinci, A, Caruso, A, Grotti, A, Iacovella, A, La Brocca, A, Mangioncalda, A, Longanesi, Am, Susi, B, Barletta, C, Braglia, D, Coen, D, Tazza, D, Gottardi, E, Palego, E, Urbano, E, Bar, F, Bussani, F, De Giorgi, F, Esposito, F, Fabi, F, Lotti, F, Miglio, F, Moscariello, F, Pertoldi, F, Sardella, F, Tosato, F, Abregal, G, Baldi, G, Carbone, G, Cerqua, G, Giagnorio, G, Pia, G, Piazza, G, Tedesco, G, Sallustio, Gf, Morana, I, Beringheli, L, Jannotti, L, Spinsi, L, Zulli, L, Cavazza, M, De Simone, M, Galletti, M, Gioffre', Maria, Greco, M, Longoni, M, Luppi, M, Magnani, M, Mazzone, M, Pastorello, M, Pazzaglia, M, Ravaglia, M, Zammataro, M, Zanna, M, Bressan, Ma, Saggese, Mp, Gentiloni Silveri, N, Scopetta, N, De Mitri, O, Fantin, O, Boscolo, P, Cancemi, P, De Angelis, P, Di Pietro, P, Mosca, P, Pacelli, P, Torboli, P, Copetti, R, Fazio, R, Losordo, R, Melandri, R, Papitto, R, Chiaravalle, S, Orlando, S, Sturlese, U, Di Grande, A, Narbone, G, Zimmermann, H, Martinelli, L, Clanchini, V, Paternosto, D, Fiorilli, M, Del Prato, C, Becheri, M, Lanigra, M, Guerra, G, Sinno, C, Soragna, A, Ferranio, Mp, Bua, V, Capra, R, and Lualdi, E.

Subjects
Italian Emergency Departments Quality Multi-centre study, Patient Admission, Italy, Health Care Surveys, Humans, Triage, Emergency Service, Hospital, Quality of Health Care
Abstract

A multi-centre study has been conducted, during 2005, by means of a questionnaire posted on the Italian Society of Emergency Medicine (SIMEU) web page. Our intention was to carry out an organisational and functional analysis of Italian Emergency Departments (ED) in order to pick out some macro-indicators of the activities performed. Participation was good, in that 69 ED (3,285,440 admissions to emergency services) responded to the questionnaire.The study was based on 18 questions: 3 regarding the personnel of the ED, 2 regarding organisational and functional aspects, 5 on the activity of the ED, 7 on triage and 1 on the assessment of the quality perceived by the users of the ED.The replies revealed that 91.30% of the ED were equipped with data-processing software, which, in 96.83% of cases, tracked the entire itinerary of the patient. About 48,000 patients/year used the ED: 76.72% were discharged and 18.31% were hospitalised. Observation Units were active in 81.16% of the ED examined. Triage programmes were in place in 92.75% of ED: in 75.81% of these, triage was performed throughout the entire itinerary of the patient; in 16.13% it was performed only symptom-based, and in 8.06% only on-call. Of the patients arriving at the ED, 24.19% were assigned a non-urgent triage code, 60.01% a urgent code, 14.30% a emergent code and 1.49% a life-threatening code. Waiting times were: 52.39 min for non-urgent patients, 40.26 min for urgent, 12.08 for emergent, and 1.19 for life-threatening patients.

Published
2007

36. Genes from Sulfolobus solfataricus P2 involved in polysaccharide degradation

Author

Aurilia V., Mazzone M., Cobucci-Ponzano B., Moracci M., Rossi M., and Cannio R.

Abstract

On the basis of the complete genome of S. solfataricus P2 recently publishe, three putative extracellular cellulases (Sso1354, Sso1949, Sso2534) were identified. In particular, Sso2534 is a carboxy-methyl cellulose induced cellulase gene and its enzyme activity was well characterized. Moreover, the S. solfataricus P2 genome analysis revealed ORFs addressed to hydrolyse oligosaccharides to di- and monosaccharides. We have cloned and expressed three open reading frames (ORFs) involved in the sugar metabolism.

Published
2004

38. Chapter 12: FT3, an experiment to study burning plasma physics issues in deuterium plasmas

Author

Romanelli, F, Gormezano, A, Lucci, C, Pizzuto, F, Righetti, A, Angelone, G, Alessandrini, M, Baldarelli, C, Barbato, M, Batistoni, E, Brolatti, F, Bruschi, G, Candela, A, Capriccioli, G, Claesen, A, Cirant, R, Coletti, S, Cocilovo, A, Crescenzi, V, Crisanti, C, Cucchiaro, F, Di Pace, A, Esposito, L, Frigione, B, Garzotti, D, Gormezano, L, Granucci, C, Lo Bue, G, Lucci, A, Maddaluno, F, Marinucci, G, Mazzone, M, Mazzitelli, G, Nardi, G, Nowak, C, Papastergiou, S, Pericoli Ridolfini, S, Pieroni, V, Pillon, L, Pizzuto, M, Polinari, A, Ramogida, P, Ramponi, G, Riccardi, G, Righetti, B, Rita, G, Rollet, C, Roccella, S, Romanelli, M, Santinelli, F, Sassi, M, Semeraro, M, Simonetto, L, Smeulders, A, Sozzi, P, Talarico, C, Vlad, C, and Zonca, G

Subjects
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
Published
2004

40. Studio Osservazionale Multicentrico

Author

Cremonesi, P, Sartini, M, Tamagno, R, Randelli, A, Orlando, P, Gruppo Simeu: Carinci, A, Caruso, A, Grotti, A, Iacovella, A, La Brocca, A, Mangiocalda, A, Longanesi, Am, Susi, B, Barletta, C, Braglia, D, Coen, D, Tazza, D, Gottardi, E, Palego, E, Urbano, E, Bar, F, Bussani, F, De Giori, F, Esposito, F, Fabi, F, Lotti, F, Miglio, F, Moscariello, F, Pertoldi, F, Sardella, F, Tosato, F, Abregal, G, Baldi, G, Carbone, G, Cerqua, G, Giagnorio, G, Pia, G, Piazza, G, Tedesco, G, Sallustio, Gf, Morana, I, Berigheli, L, Jannotti, L, Spinsi, L, Zulli, L, Cavazza, M, De Simone, M, Galletti, M, Gioffre', Maria, Greco, M, Longoni, M, Luppi, M, Magnani, M, Mazzone, M, Pastorello, M, Pazzaglia, M, Ravaglia, M, Zammataro, M, Zanna, M, Bressan, Ma, Maggese, Mp, Gentiloni Silveri, N, Scopetta, N, De Mitri, O, Fantin, O, Boscolo, P, Cancemi, P, De Angelis, P, Di Pietro, P, Mosca, P, Pacelli, P, Torboli, P, Copetti, R, Fazio, R, Lo Sordo, R, Melandri, R, Papitto, R, Chiaravalle, S, Orlando, S, and Sturlese, U.

Published
2004

50. Enzymatic synthesis of 2-deoxy-beta-glucosides and stereochemistry of beta-glicosidase from Sulfolobus solfataricus on glucal

Author

Trincone A., Pagnotta E., Rossi M., Mazzone M., and Moracci M.

Abstract

The hyperthermophilic member of family 1 of the glycosyl hydrolases, the -glycosidase from the archaeon Sulfolobus solfataricus (Ss-gly), has been used for an efficient synthesis of -2-deoxyglucosides and for stereochemical studies of the reactions of glucal in the presence of alkyl and pyranosidic acceptors. Protonation of the double bond of glucal resulting in the equatorially disposed proton was observed and an indication of the protonating amino acid in the active site was obtained by the use of a mutant enzyme. The regioselectivity in the formation of -2-deoxyglucosides of pyranosidic acceptors is different from that reported for mesophilic biocatalysts.

Published
2001

Catalog

Books, media, physical & digital resources
See catalog results