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The anti-inflammatory and anti-nociceptive activities of the root extract of Elephantorrhiza elephantina (Burch.) Skeels (Fabaceae) were investigated using wistar rats. The extract was administered intraperitoneally (i.p) to rats at graded doses of 50, 100 and 200 mg/kg BWt. Carrageenan andHistamine were injected into rat paws sub-plantar to induce paw oedema, while acetic acid and formalin were injected i.p to induce pain. Indomethacin (10 mg/kg) was used as reference drug, whereas thevehicle [0.9% normal saline in 3% tween 80 (2 ml/kg)] was used as negative control. Acute toxicity was tested in rats at doses of 200, 400, 800 and 1600 mg/kg BWt. Compared to control, the aqueous extractof E. elephantina at all doses investigated significantly (P < 0.05) reduced the formation of oedema induced by Carrageenan and Histamine. The extract also caused a significant (P < 0.05) reduction in writhings in the acetic acid test and licking time in the formalin test. The rats did not show any signs of acute toxicity. The study revealed the anti-inflammatory and anti-nociceptive activities of the aqueous extract of E. elephantina, which may be due to the presence of phytochemical constituents such astannins and flavonoids. The acute toxicity test showed that the plant is relatively safe to use.

In spite of predictions of communal rangeland collapse due to continuous grazing and increased livestock populations, this grazing system remains prevalent in communal areas, suggesting animals utilise heterogeneity found in these areas. A study was conducted to compare biomass and herbaceous species composition in patches frequently grazed by cattle to randomly selected control sites in three communal areas located in Lesotho Highland Basalt Grassland (Magwiji), Bhisho Thornveld (Mnyameni) and Tsomo Grassland (Cala). The relationship of vegetation parameters in frequently selected patches to the corresponding soil properties, topography and human impact was also examined. Biomass of frequently selected patches was significantly (p < 0.05) higher in the dry season (June) at Magwiji (528 kg ha-1) than in less frequently selected patches (130 kg ha-1). There was an association between sites selected in winter and soil organic carbon, and these sites were dominated by Cynodon dactylon and Pennisetum clandestinum. The floristic patterns observed in Magwiji were associated with soil organic carbon content. Low-lying swampy patches had high soil pH in Cala, while mountain top soils in Magwiji had low electrical conductivity and these areas selected in winter were associated with grass species such as Eragrostis superba and Heteropogon contortus.Keywords: cattle; graze; key resource areas; livestockAfrican Journal of Range & Forage Science 2010, 27(3): 151–162