86 results on '"Nguyen, Tien-Trung"'
Search Results
2. Role of O–H⋯O/S conventional hydrogen bonds in considerable Csp2–H blue-shift in the binary systems of acetaldehyde and thioacetaldehyde with substituted carboxylic and thiocarboxylic acids
- Author
-
Nguyen Truong An, Nguyen Thi Duong, Nguyen Ngoc Tri, and Nguyen Tien Trung
- Subjects
General Chemical Engineering ,General Chemistry - Abstract
The presence of O–H⋯O/S conventional hydrogen bonds in the complex governs a significant blue shift of Csp2–H bonds.
- Published
- 2022
3. Theoretical Aspects of Nonconventional Hydrogen Bonds in the Complexes of Aldehydes and Hydrogen Chalcogenides
- Author
-
Minh Tho Nguyen, Vu Thi Ngan, Nguyen Thi Thanh Cuc, Cam-Tu D. Phan, Nguyen Tien Trung, and Nguyen Thi Ai Nhung
- Subjects
Red shift ,Crystallography ,Hydrogen ,Chemistry ,Hydrogen bond ,Ab initio quantum chemistry methods ,Halogen ,Molecule ,chemistry.chemical_element ,Physical and Theoretical Chemistry ,Ternary operation ,Blueshift - Abstract
Hydrogen bonds (H-bonds) in the complexes between aldehydes and hydrogen chalcogenides, XCHO...nH2Z with X = H, F, Cl, Br, and CH3, Z = O, S, Se, and Te, and n = 1,2, were investigated using high-level ab initio calculations. The Csp2-H...O H-bonds are found to be about twice as strong as the Csp2-H...S/Se/Te counterparts. Remarkably, the S/Se/Te-H...S/Se/Te H-bonds are 4.5 times as weak as the O-H...O ones. The addition of the second H2Z molecule into binary systems induces stronger complexes and causes a positive cooperative effect in ternary complexes. The blue shift of Csp2-H stretching frequency involving the Csp2-H...Z H-bond sharply increases when replacing one H atom in HCHO by a CH3 group. In contrast, when one H atom in HCHO is substituted with a halogen, the magnitude of blue-shifting of the Csp2-H...Z H-bond becomes smaller. The largest blue shift up to 92 cm-1 of Csp2-H stretching frequency in Csp2-H...O H-bond in CH3CHO...2H2O has rarely been observed and is much greater than that in the cases of the Csp2-H...S/Se/Te ones. The Csp2-H blue shift of Csp2-H...Z bonds in the halogenated aldehydes is converted into a red shift when H2O is replaced by a heavier analogue, such as H2S, H2Se, or H2Te. The stability and classification of nonconventional H-bonds including Csp2-H...Se/Te, Te-H...Te, and Se/Te-H...O have been established for the first time.
- Published
- 2021
4. SERS Chemical Enhancement of 2,4,5-Trichlorophenoxyacetic Acid Adsorbed on Silver Substrate
- Author
-
Duy Quang Dao, Thi Chinh Ngo, Thi Thuy Huong Le, Quang Thang Trinh, Thi Le Anh Nguyen, Bui The Huy, Nguyen Ngoc Tri, Nguyen Tien Trung, and Minh Tho Nguyen
- Subjects
Electron transfer ,symbols.namesake ,Adsorption ,Chemistry ,Cluster (physics) ,symbols ,Nanoparticle ,Molecule ,Substrate (chemistry) ,Density functional theory ,Physical and Theoretical Chemistry ,Photochemistry ,Raman spectroscopy - Abstract
Surface-enhanced Raman spectroscopy (SERS) was employed to gain an understanding of the chemical enhancement mechanism of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), an Agent Orange, adsorbed on a silver substrate surface. Experimental measurements were performed using a micro-Raman spectrophotometer with an excitation wavelength of 532 nm and successfully detected 2,4,5-T at a relatively low concentration of 0.4 nM. Density functional theory (DFT) calculations on the interactions of the 2,4,5-T molecule with some small silver clusters, Agn with n = 4, 8, and 20, as well as with extended Ag surfaces, demonstrate that the most stable adsorption configuration is formed via coordination of Cl9 sites and carbonyl C═O group on the 2,4,5-T ligand to the Ag atoms on surfaces. Analyses of charge transfer mechanism and frontier orbitals distributions show an electron transfer from 2,4,5-T to the cluster in the ground state, and an inversed trend occurs for the excited singlet state process, consequently leading to a chemical enhancement of SERS signals. The obtained results are of importance for subsequent work in guiding the design of mobile sensors specifically used for services of rapid screening and detection of these toxic compounds present in the environment, as well as agricultural and food products. Extensive computations pointed out that small silver clusters, in particular of Ag20 size, can be used as appropriate models for a metal nanoparticle surface.
- Published
- 2021
5. Experimental and theoretical studies on the synthesis of 1,4,5-trisubstituted pyrrolidine-2,3-diones
- Author
-
Nguyen Tran Nguyen, Vo Viet Dai, Nguyen Ngoc Tri, Luc Van Meervelt, Nguyen Tien Trung, and Wim Dehaen
- Subjects
Chemistry ,Science & Technology ,DERIVATIVES ,3-pyrroline-2-one ,Organic Chemistry ,Physical Sciences ,Chemistry, Organic ,4-acetyl-3-hydroxy-3-pyrroline-2-ones ,1,5-dihydro-2H-pyrrol-2-ones ,pyrrolidine-2,3-dione ,2-pyrrolidinone derivative ,3-PYRROLIN-2-ONE ,ANTIMICROBIAL ACTIVITY - Abstract
Substituted 4-acetyl-3-hydroxy-3-pyrroline-2-ones have been prepared via three-component reactions and the tautomerism of these 3-pyrroline-2-ones is due to the slight difference of energy, and the significantly large rate constant of transformation between two tautomers. 1,4,5-Trisubstituted pyrrolidine-2,3-dione derivatives were prepared from the above mentioned 2-pyrrolidinone derivatives and aliphatic amines, which exist in enamine form and are stabilized by an intramolecular hydrogen bond. A possible reaction mechanism between 3-pyrroline-2-one and aliphatic amine (CH3NH2) was proposed based on computational results and the main product is formed favorably following the PES via the lowest ΔG # pathway in both the gas-phase and an ethanol solvent model. DFT calculations showed that kinetic selectivity is more significant than thermodynamic selectivity for forming main products. ispartof: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY vol:18 pages:1140-1153 ispartof: location:Germany status: published
- Published
- 2022
6. Role of O-H⋯O/S conventional hydrogen bonds in considerable C
- Author
-
Nguyen Truong, An, Nguyen Thi, Duong, Nguyen Ngoc, Tri, and Nguyen Tien, Trung
- Abstract
Stable binary complexes of RCZOH⋯CH
- Published
- 2022
7. Nervione, a new benzofuran derivative from Nervilia concolor
- Author
-
Nguyen-Minh-An Tran, Mai Dinh Tri, Cong-Luan Tran, Cam-Tu D. Phan, Thanh-Nha Tran, Thuc-Huy Duong, Thi-Ngoc-Mai Tran, Nhat-Minh Phan, Nguyen Tien-Trung, and Thanh-Hung Do
- Subjects
biology ,010405 organic chemistry ,Stereochemistry ,Organic Chemistry ,Absolute configuration ,Plant Science ,biology.organism_classification ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Analytical Chemistry ,010404 medicinal & biomolecular chemistry ,chemistry.chemical_compound ,chemistry ,Rhamnetin ,Nervilia ,Benzofuran ,Spectroscopy ,Two-dimensional nuclear magnetic resonance spectroscopy ,Derivative (chemistry) - Abstract
A new benzofuran derivative, nervione (1), was isolated from Nervilia concolor (Blume) Schltr. (Orchidaceae). Eight previously reported compounds were also isolated: 5,7-dimethoxyflavone (2), 3,5,7-trimethoxyflavone (3), 7-methoxyflavone (4), 3,7-dimethoxy-5-hydroxyflavone (5), tetramethylscutellarein (4',5,6,7-tetramethoxyflavone) (6), 5,7-dimethoxy-4'-hydroxyflavone (7), rhamnetin (8), and 5,7-dihydroxy-3’,4’-dimethoxyflavone (9). The structures were elucidated by 1D, 2D NMR, and HRESIMS spectroscopy in addition to the literature. The relative configuration of 1 was defined using DP4+ probability while its absolute configuration was defined by comparison of the ECD spectrum of 1 with those of previously reported compounds. All isolated compounds were evaluated for alpha-glucosidase inhibition, revealing weak or no activity.
- Published
- 2021
8. A new 26-norlanostane from Phlogacanthus turgidus growing in Vietnam
- Author
-
Nguyen Tien Trung, Trần Thị Ngọc Mai, Mai Dinh Tri, Luu Hong Truong, Thi-Phuong Nguyen, Cam-Tu D. Phan, Mai Thanh Chi, Nguyen Tan Phat, Thuc-Huy Duong, Chi Hien Dang, Phan Nhat Minh, and Nguyen Kim Tuyen Pham
- Subjects
Pharmacology ,Betulin ,biology ,Traditional medicine ,010405 organic chemistry ,Organic Chemistry ,Acanthaceae ,Pharmaceutical Science ,General Medicine ,biology.organism_classification ,01 natural sciences ,Lanostane ,Phlogacanthus ,0104 chemical sciences ,Analytical Chemistry ,010404 medicinal & biomolecular chemistry ,chemistry.chemical_compound ,Triterpenoid ,Complementary and alternative medicine ,chemistry ,Drug Discovery ,Molecular Medicine ,Lupeol - Abstract
Chemical investigation on chloroform extract of Phlogacanthus turgidus led to the isolation of one new compound namely turgidol, together with five known triterpenoids, lupeol, lupenone, betulin, betulinic acid, and taraxerol. Their structures and stereochemistry have been determined by 1 D and 2 D NMR analysis, high resolution mass spectrometry, and compared with those in literatures. The relative configuration of turgidol was defined using DFT-NMR chemical shift calculations and subsequent DP4+ probability method. Turgidol, betulin, and betulinic acid were evaluated for cytotoxic activity toward K562 cancer cell line and the alpha-glucosidase inhibition.
- Published
- 2021
9. A Study on Structure, Stability, Cooperativity and Hydrogen Bond in the Complexes of nHCHO and nH2O (n=1-3) by Quantum Chemical Method
- Author
-
Nguyen Tien Trung, Nguyen Phi Hung, Nguyen Truong An, Ngo Vuong Hoang, Ngo Thi Hong Nhung, Le Thi Tu Quyen, and Ho Cong Hau
- Abstract
Eight stable structures of nHCHO∙∙∙nH2O (n=1-3) were observed on potential surface energy at the MP2/aug-cc-pVDZ level of theory. All complexes were mainly stabilized by O-H∙∙∙O hydrogen bond and an additional contribution of Csp2-H∙∙∙O one. The larger positive cooperativity when adding H2O as compared to HCHO molecule is the most important factor in complex stabilization. The obtained results show that the O-H∙∙∙O is red-shifting hydrogen bond while Csp2-H∙∙∙O belongs to blue-shifting hydrogen bond. It is remarkable that an addition of H2O/HCHO into the binary system leads a Csp2-H bond contraction and an increase of its stretching frequency in Csp2-H∙∙∙O hydrogen bond, in which the larger marnitude of its blue-shifting enhancement is found as adding H2O molecule. This result is mainly governed by a decrease of electron density at σ*(Csp2-H) orbital and an increase in the s-character percentage of the Csp2 (Csp2-H).
- Published
- 2022
10. Novel photocatalytic performance of magnetically recoverable MnFe2O4/BiVO4 for polluted antibiotics degradation
- Author
-
Thanh-Dong Pham, Nguyen Tien Trung, Mai Hung Thanh Tung, Nguyen Thuy Huong, Nguyen Thi Dieu Cam, Cao Van Hoang, Tran Thi Thu Phuong, Hai Dinh Pham, and Tran Thi Thu Hien
- Subjects
010302 applied physics ,Materials science ,Process Chemistry and Technology ,Radical ,chemistry.chemical_element ,Heterojunction ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,Oxygen ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,chemistry ,0103 physical sciences ,Oxidizing agent ,Materials Chemistry ,Ceramics and Composites ,Valence band ,Photocatalysis ,Degradation (geology) ,0210 nano-technology ,Visible spectrum - Abstract
In the study, we successfully decorated MnFe2O4 on BiVO4 to highly improve its photocatalytic activity for degradation of tetracycline as well as its magnetically recovery. The decoration of MnFe2O4 on BiVO4 led to formation of MnFe2O4/BiVO4 Z scheme heterojunction to effectively prevent the charge recombination in each material. Upon visible light, the MnFe2O4/BiVO4 heterojunction produced significant available amounts of e− and h+ existing in the conduction band of the MnFe2O4 and the valence band of the BiVO4, respectively. These produced e− on the conduction band of the MnFe2O4, which reduction potential was approximately −0.41 eV, exhibited strong reduction potential reducing oxygen to produce •O2− radicals while h+ on the valence band of the BiVO4, which oxidation potential was 2.77 eV, showed strong oxidation potential oxidizing water and hydroxyl groups to produce •OH radicals. These generated active oxygen radicals effectively degraded TC in water (~92%). The used photocatalysts were easily recovered from photocatalytic suspension using an external magnet due to high magnetically activity of the MnFe2O4, which tightly bonded with BiVO4 in the MnFe2O4/BiVO4 heterojunction. Finally, the recovered MnFe2O4/BiVO4 heterojunction was very active and stable for tetracycline degradation in long-term process.
- Published
- 2021
11. Manilkzapotane, a novel dimeric alkylresorcinol derivative from the stem bark of Manilkara zapota
- Author
-
Cam-Tu D. Phan, Huu-Hung Nguyen, Vassana Musa, Jirapast Sichaem, Ngoc-Hong Nguyen, Van-Kieu Nguyen, Thuc-Huy Duong, Thanatip Ruksilp, and Nguyen Tien Trung
- Subjects
Pharmacology ,Stem bark ,biology ,Ergosterol peroxide ,010405 organic chemistry ,Organic Chemistry ,Pharmaceutical Science ,General Medicine ,Manilkara ,biology.organism_classification ,01 natural sciences ,Sapotaceae ,0104 chemical sciences ,Analytical Chemistry ,Taraxerol ,010404 medicinal & biomolecular chemistry ,chemistry.chemical_compound ,Alkylresorcinol ,Complementary and alternative medicine ,chemistry ,Drug Discovery ,Molecular Medicine ,Organic chemistry ,Derivative (chemistry) ,Lupeol - Abstract
A novel dimeric alkylresorcinol derivative, manilkzapotane (1), along with seven known compounds, lupeol acetate (2), lupeol (3), arjunolic acid (4), ergosterol peroxide (5), taraxerol (6), hederagonic acid (7), and glochidiol (8) were isolated from the stem bark of Manilkara zapota. Their structures were determined on the basis of spectroscopic data. DFT-NMR chemical shift calculations and a modified probability (DP4+) method were applied to define the relative configuration of 1. To the best of our knowledge, this represents the first isolation of a dimeric alkylresorcinol derivative from the Sapotaceae family.
- Published
- 2020
12. Manuscript Matcher: A Tool for Finding the Best Journal
- Author
-
Nguyen Danh Nam, Tran Trung, Nguyen Tien Trung, and Trinh Phuong Thi Thao
- Published
- 2022
13. Development of g-C3N4/BiVO4 Binary Component Heterojunction as an Advanced Visible Light-Responded Photocatalyst for Polluted Antibiotics Degradation
- Author
-
Mai Hung Thanh Tung, Thi Thu Phuong Nguyen, Hai Dinh Pham, Nguyen Thi Dieu Cam, Nguyen Minh Tri, Thanh-Dong Pham, Van Tang Nguyen, Van-Duong Dao, Nguyen Tien Trung, Cao Van Hoang, Doan Van Thuan, and Tran Thi Thu Phuong
- Subjects
Materials science ,Valence (chemistry) ,010405 organic chemistry ,Band gap ,Radical ,Heterojunction ,General Chemistry ,010402 general chemistry ,Photochemistry ,01 natural sciences ,Catalysis ,0104 chemical sciences ,Excited state ,Photocatalysis ,Irradiation ,Visible spectrum - Abstract
g-C3N4/BiVO4, binary component heterojunction materials, were successfully synthesized for novel photocatalytic tetracycline (TC) decomposition. In the prepared binary component heterojunction, BiVO4 was well distributed on g-C3N4 layer. In addition, BiVO4 and g-C3N4 was intimately contacted. Both BiVO4 and g-C3N4, which band gap energies were approximately 2.46 and 2.71 eV, respectively, would also absorb significant amount of visible light to excite electrons (e−) from their valence bands to conduction bands. Thus, the e− on the conduction band of the BiVO4 could quickly transfer and combine with the h+ on the valence band of the g-C3N4. Therefore, the g-C3N4/BiVO4 could be easily excited by incident visible irradiation to produce large number of h+ on the valence band of the BiVO4 and e− on the conduction band of the g-C3N4. These produced e− and h+ were strong enough for reactions with water and oxygen to product huge amounts of hydroxyl radicals for novel TC degradation. The photocatalytic performance of these g-C3N4/BiVO4 materials highly depended on weight ratio of these used precursors. The g-C3N4/BiVO4-10 material, which the g-C3N4:BiVO4 weight ratio was 10%, presented the highest tetracycline degradation efficiency (95%). This was due to these excess of g-C3N4 covered more BiVO4 surface preventing incident light reaching to the material and also represented as active sites for recombination of charges (e− and h+) decreasing photocatalytic efficiency of the system. Finally, the synthesized g-C3N4/BiVO4 presented novel durability during long-term photocatalysis.
- Published
- 2020
14. SERS Spectra of the Pesticide Chlorpyrifos Adsorbed on Silver Nanosurface: The Ag20 Cluster Model
- Author
-
Thi Chinh Ngo, Quang Thang Trinh, Nguyen Thi Thai An, Nguyen Ngoc Tri, Nguyen Tien Trung, Dinh Hieu Truong, Bui The Huy, Minh Tho Nguyen, and Duy Quang Dao
- Subjects
Quantum chemical ,Materials science ,02 engineering and technology ,Pesticide ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Spectral line ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,symbols.namesake ,chemistry.chemical_compound ,General Energy ,Adsorption ,chemistry ,Chemical physics ,Chlorpyrifos ,Cluster (physics) ,symbols ,Quantitative Biology::Populations and Evolution ,Density functional theory ,Physical and Theoretical Chemistry ,0210 nano-technology ,Raman scattering - Abstract
Surface enhanced Raman scattering (SERS) experiments and quantum chemical calculations (using density functional theory) on the interactions of chlorpyrifos (CPF), which is an intensively used pest...
- Published
- 2020
15. A new diterpenoid from the leaves of Phyllanthus acidus
- Author
-
Thi-Ngoc-Mai Tran, Thuc-Huy Duong, Thi-Bich-Ngoc Dao, Nakorn Niamnont, Dinh-Tri Mai, Hoang-Chuong Nguyen, Jirapast Sichaem, Cam-Tu D. Phan, Vu-Duy Nguyen, and Nguyen Tien Trung
- Subjects
Spruceanol ,Phyllanthus ,biology ,Traditional medicine ,Chemistry ,Organic Chemistry ,Plant Science ,Phyllanthaceae ,biology.organism_classification ,Biochemistry ,Terpenoid ,Analytical Chemistry - Abstract
A new diterpenoid, phyllane C (1), along with three known compounds, ovoideal E (2), spruceanol (3), and fluacinoid B (4) were isolated from the leaves of Phyllanthus acidus growing in Thailand. The structures were determined by analysis of their MS and NMR data as well as by comparison with literature values. DFT-NMR chemical shift calculations and subsequent DP4/DP4+ probability methods were applied to define the relative configuration of 1. Compound 3 showed a weak cytotoxicity against K562 cell line (IC50 41.9 ± 2.31 µg/mL).
- Published
- 2020
16. Growth Pattern, Stability, and Properties of Complexes of C2H5OH and nCO2 (n = 1–5) Molecules: A Theoretical Study
- Author
-
Nguyen Thi Ai Nhung, Nguyen Tien Trung, and Cam-Tu D. Phan
- Subjects
Chemistry ,General Chemical Engineering ,Intermolecular force ,Atoms in molecules ,Cooperative binding ,General Chemistry ,Chalcogen ,Crystallography ,Atom ,Molecule ,Lone pair ,QD1-999 ,Natural bond orbital - Abstract
This work is dedicated to theoretically investigate the formation process of C2H5OH···nCO2 (n = 1-5) complexes and to shed light on the nature of interactions formed under the variation of CO2 concentration. It is found that CO2 molecules tend to locate around the polarized -OH group to interact with the lone pairs of the O atom. The interaction of ethanol with three CO2 molecules (C2H5OH···3CO2) induces the most stable structure in the sequence considered. The atoms in molecules (AIM), NCIplot, and natural bond orbital (NBO) analyses point out that the Oethanol···CCO2 tetrel bond overcomes hydrogen, chalcogen, and CO2···CO2 tetrel-bonded interactions and mainly contributes to the strength of C2H5OH···nCO2 (n = 1-5) complexes. All intermolecular interactions in the examined complexes are weakly noncovalent, and their positive cooperativity is evaluated to be slightly weaker than that of CO2 pure systems. SAPT2+ and molecular electrostatic potential (MEP) calculations indicate that the electrostatic force is the main factor underlying the attractive interplay in the complexes of C2H5OH and CO2.
- Published
- 2020
17. A theoretical study of X-H∙∙∙π and X∙∙∙π interactions in the complexes of furan, thiophene, pyrrole and hydrogen halides
- Author
-
Nguyen Thi Hong Man, Do Thi Hong Le, Nguyen Ngoc Tri, and Nguyen Tien Trung
- Subjects
chemistry.chemical_compound ,Halogen bond ,chemistry ,Hydrogen ,Hydrogen bond ,Furan ,Thiophene ,chemistry.chemical_element ,Halide ,Medicinal chemistry ,Pyrrole - Published
- 2020
18. Molecular docking studies of Vinca alkaloid derivatives on Tubulin
- Author
-
Nguyen Tien Trung, Ngo Quoc Anh, Pham Minh Quan, Vo Ngoc Binh, and Vu Thi Ngan
- Subjects
Tubulin ,biology ,Chemistry ,Stereochemistry ,medicine.drug_class ,biology.protein ,medicine ,AutoDock ,Vinca alkaloid - Published
- 2019
19. Transformation between Hexagonal Prism and Antiprism of the Singly and Doubly Cr-Doped Ge12 Clusters
- Author
-
Vu Thi Ngan, Cam-Tu Phan Dang, Nguyen Tien Trung, and Hung Tan Pham
- Subjects
Hexagonal prism ,Hexagonal antiprism ,010304 chemical physics ,Chemistry ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Crystallography ,Ferromagnetism ,Antiprism ,Ferrimagnetism ,0103 physical sciences ,Physics::Atomic and Molecular Clusters ,Cluster (physics) ,Physical and Theoretical Chemistry ,Triplet state ,Ground state - Abstract
Structural transformation is a unique characteristic of atomic clusters, but it turns out very different from cluster to cluster. This theoretical study proves that the isomeric transformation between hexagonal prism and hexagonal antiprism is found for the doubly doped Cr2Ge12 cluster but not for singly doped CrGe12 cluster. We confirm that the ground state of CrGe12 is the distorted hexagonal prism C2h at the 3Bg triplet state instead of various shapes predicted in the previous studies. Upon comparison between the estimation at the B3P86/6-311+G(d) level of theory and the detachment energies measured by photoelectron spectroscopy, hexagonal antiprismatic shape is identified as the most stable isomer of the Cr2Ge12 cluster and it is easy to transform to the hexagonal prism-a less stable isomer by the rotation of the hexagonal rings. That is the first evidence for the structural transformation between a hexagonal prism and an antiprism of the germanium clusters, referring to the ability of Ge-based clusters in the formation of tubular geometry by doping Cr atoms. All the low-energy isomers of both Cr-doped germanium clusters have high magnetic moments. Interestingly, there is a tuning in magnetic properties of Cr2Ge12 from the ferromagnetism of the lowest-lying hexagonal antiprism to the ferrimagnetism of the higher-energy hexagonal prism. The stronger Cr-Cr bond and stronger interaction between the Cr2 moiety and the antiprism cage are accounted for by the higher stability of the hexagonal antiprismatic isomer.
- Published
- 2019
20. Indicuen, a new hopane from
- Author
-
Thi-Quynh-Trang, Nguyen, Nguyen-Kim-Tuyen, Pham, Nguyen Tien, Trung, Nguyen Truong, An, Dinh-Tri, Mai, Jirapast, Sichaem, Bui-Linh-Chi, Huynh, Nguyen Thi Hong, Anh, Ngoc-Hong, Nguyen, and Thuc-Huy, Duong
- Abstract
One new hopane-type triterpene, indicuen (
- Published
- 2021
21. Importance of water and intramolecular interaction governs substantial blue shift of C
- Author
-
Nguyen Thi Thanh, Cuc, Nguyen Truong, An, Vu Thi, Ngan, Asit K, Chandra, and Nguyen Tien, Trung
- Abstract
Geometrical structure, stability and cooperativity, and contribution of hydrogen bonds to the stability of complexes between chalcogenoaldehydes and water were thoroughly investigated using quantum chemical methods. The stability of the complexes increases significantly when one or more H
- Published
- 2021
22. Complexes of carbon dioxide with methanol and its monohalogen-substituted: Beyond the tetrel bond
- Author
-
Cam-Tu Phan Dang and Nguyen Tien Trung
- Subjects
General Physics and Astronomy ,Physical and Theoretical Chemistry - Published
- 2022
23. Two new cycloartanes from the leaves of Combretum quadrangulare growing in Vietnam and their biological activities
- Author
-
Thi-Bich-Ngoc Dao, Dinh-Tri Mai, Thuc-Huy Duong, Huu-Hung Nguyen, Thi-Phuong Nguyen, Nguyen Tien Trung, Ngoc-Hong Nguyen, Jirapast Sichaem, Cam-Tu D. Phan, and Cong-Luan Tran
- Subjects
Antiparasitic ,medicine.drug_class ,General Chemical Engineering ,Cytotoxicity ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Antiparasitic activity ,Combretaceae ,medicine ,Combretum quadrangulare ,QD1-999 ,biology ,Traditional medicine ,Chemistry ,General Chemistry ,021001 nanoscience & nanotechnology ,biology.organism_classification ,Combretanones G and H ,0104 chemical sciences ,Cycloartane ,0210 nano-technology ,Human cancer - Abstract
Two new cycloartanes, combretanones G and H (1 and 2), were isolated from the leaves of Combretum quadrangulare. Their structures were elucidated by applying a set of spectroscopic methods, while their relative configurations were determined using DFT-NMR chemical shift calculations and subsequent assignment of DP4 probabilities. Compounds 1 and 2 are C-23/C-24 stereoisomers of the previously-reported euphonerin E. Both exhibited moderate cytotoxicity against three human cancer cell lines. Compound 2 was shown to be a potent antiparasitic. Our results confirm the traditional medicinal uses of Combretum quadrangulare in Vietnam.
- Published
- 2021
24. Prussian Blue decorated g-C3N4 – From novel synthesis to insight study on charge transfer strategy for improving visible-light driven photo-Fenton catalytic activity
- Author
-
Lan Nguyen Thi, Thi Thuy Trang Phan, Tri Nguyen Ngoc, N.S.M. Viswanath, Hang T.T. Le, Lan Tran Thi, Nguyen Tien-Trung, Le Tuan Nguyen, Dao Ngoc Nhiem, Ha Tran Huu, and Vien Vo
- Subjects
Mechanics of Materials ,Mechanical Engineering ,Materials Chemistry ,Metals and Alloys - Published
- 2022
25. Nervione, a new benzofuran derivative from
- Author
-
Cong-Luan, Tran, Mai Dinh, Tri, Nguyen, Tien-Trung, Nhat-Minh, Phan, Cam-Tu D, Phan, Thanh-Nha, Tran, Thanh-Hung, Do, Nguyen-Minh-An, Tran, Thi-Ngoc-Mai, Tran, and Thuc-Huy, Duong
- Subjects
Magnetic Resonance Spectroscopy ,Molecular Structure ,alpha-Glucosidases ,Orchidaceae ,Benzofurans - Abstract
A new benzofuran derivative, nervione (
- Published
- 2021
26. A new 26-norlanostane from
- Author
-
Mai Dinh, Tri, Nguyen Tan, Phat, Nguyen Tien, Trung, Cam-Tu D, Phan, Phan Nhat, Minh, Mai Thanh, Chi, Thi-Phuong, Nguyen, Chi Hien, Dang, Luu, Hong Truong, Nguyen Kim Tuyen, Pham, Trần Thị Ngọc, Mai, and Thuc-Huy, Duong
- Subjects
Molecular Structure ,Vietnam ,Acanthaceae ,Phytochemicals ,Humans ,Glycoside Hydrolase Inhibitors ,alpha-Glucosidases ,K562 Cells ,Antineoplastic Agents, Phytogenic ,Triterpenes - Abstract
Chemical investigation on chloroform extract of
- Published
- 2021
27. Theoretical exploitation of donor-acceptor ability in low-valent group-14 elements complexes [E(PPh3 )2 → SiH2 ]2+ (E = C to Pb) using energy decomposition analysis
- Author
-
Vo Thanh Cong, Duong Tuan Quang, Pham Van Tat, Hoang Van Duc, Huynh Thi Phuong Loan, Nguyen Thi Ai Nhung, and Nguyen Tien Trung
- Subjects
Carbon group ,Chemistry ,Physical chemistry ,Donor acceptor ,Decomposition analysis ,Bond-dissociation energy ,Energy (signal processing) - Published
- 2019
28. Theoretical study on the adsorption of benzylpenicillin molecule onto vermiculite surface
- Author
-
Nguyen Tien Trung and Nguyen Ngoc Tri
- Subjects
Adsorption ,Chemistry ,Inorganic chemistry ,medicine ,Molecule ,Vermiculite ,Benzylpenicillin ,medicine.drug - Published
- 2019
29. Antioxidant Motifs in Flavonoids: O–H versus C–H Bond Dissociation
- Author
-
Quan V. Vo, Cam-Tu D. Phan, Nguyen Minh Thong, Nguyen Tien Trung, Adam Mechler, and Pham Cam Nam
- Subjects
Ethanol ,Antioxidant ,Chemistry ,General Chemical Engineering ,medicine.medical_treatment ,food and beverages ,General Chemistry ,Ascorbic acid ,Medicinal chemistry ,Bond-dissociation energy ,Article ,Dissociation (chemistry) ,lcsh:Chemistry ,chemistry.chemical_compound ,Reaction rate constant ,lcsh:QD1-999 ,medicine ,heterocyclic compounds ,Trolox ,Quercetin - Abstract
Flavonoids provide potential health benefits due to their antioxidant properties. The antioxidant activity of natural flavonoids is primarily exerted by phenolic hydroxyl groups; however, C–H bonds also contribute to these properties. In this study, the contributions of phenolic groups and C–H bonds to the antioxidant properties of 13 flavonoids were investigated by using the (RO)B3LYP/6-311++G(2df,2p)//B3LYP/6-311G(d,p) model chemistry in the gas phase and water and ethanol solvents. It was found that the C–H bonds have lower bond dissociation energies than O–H bonds in the 4-carbonyl and/or 3-hydroxyl group containing flavonoids and hence define antioxidant activity. The HOO· radical scavenging of the selected flavonoids is also investigated in detail through the potential energy surface, natural bond orbitals, and kinetic calculations. It was found that the favored radical scavenging mechanism of the flavonoids is hydrogen atom transfer, with the gas phase rate constants in the range of 7.23 × 103–2.07 × 109 L·mol–1·s–1. The results suggest that the flavonoids, isomelacacidin, isoteracacidin, melacacidin, and teracacidin, have antioxidant properties as high as typical phenolic compounds such as quercetin, trans-resveratrol, trolox, and ascorbic acid.
- Published
- 2019
30. A sesquiterpenoid tropolone and 1,2,3,4-tetrahydronaphthalene derivatives from Olax imbricata roots
- Author
-
Phung Kim Phi Nguyen, Lien T.M. Do, Nga Thi Vo, Cam-Tu D. Phan, Nguyen Tien Trung, Suong Thi Minh Huynh, Thammarat Aree, Santi Tip-pyang, and Huong Minh Nguyen
- Subjects
Circular dichroism ,Tetrahydronaphthalenes ,Stereochemistry ,Plant Roots ,01 natural sciences ,Tropolone ,chemistry.chemical_compound ,Cell Line, Tumor ,Drug Discovery ,Ic50 values ,Humans ,Cytotoxicity ,Olax ,Pharmacology ,Molecular Structure ,biology ,010405 organic chemistry ,General Medicine ,biology.organism_classification ,Antineoplastic Agents, Phytogenic ,0104 chemical sciences ,010404 medicinal & biomolecular chemistry ,Vietnam ,chemistry ,Methanol ,Cancer cell lines ,Olacaceae ,Two-dimensional nuclear magnetic resonance spectroscopy - Abstract
The methanol extract of Olax imbricata roots afforded one new sesquiterpenoid tropolone and three new 1,2,3,4-tetrahydronaphthalene derivatives, olaximbrisides A–D (1–4). Their structures were determined by 1D and 2D NMR experiments in combination of HRESIMS. The relative configurations were assigned by the NOESY experiments. The absolute configurations were established by a combination of X-ray diffraction analysis and electronic circular dichroism (ECD) experiments. All isolated compounds were evaluated for their cytotoxic effects against some cancer cell lines. Among them, compound 1 exhibited the cytotoxicities against MCF-7, HepG2 and LU cell lines with IC50 values of 16.3, 34.3 and 8.0 μM, respectively.
- Published
- 2019
31. Insights into the adsorption of organic molecules on rutile TiO2 (1 1 0) surface: A theoretical study
- Author
-
Ho Quoc Dai, Nguyen Ngoc Tri, and Nguyen Tien Trung
- Subjects
Surface (mathematics) ,Adsorption ,Materials science ,Chemical engineering ,Rutile ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,0210 nano-technology ,01 natural sciences ,0104 chemical sciences ,Organic molecules - Published
- 2018
32. Indicuen, a new hopane from Parmotrema indicum Hale growing in Vietnam
- Author
-
Bui-Linh-Chi Huynh, Thi-Quynh-Trang Nguyen, Nguyen-Kim-Tuyen Pham, Dinh-Tri Mai, Nguyen Truong An, Nguyen Tien Trung, Nguyen Thi Hong Anh, Thuc-Huy Duong, Jirapast Sichaem, and Ngoc-Hong Nguyen
- Subjects
chemistry.chemical_classification ,biology ,Chemistry ,Stereochemistry ,Organic Chemistry ,Substituent ,Parmotrema ,Plant Science ,biology.organism_classification ,Biochemistry ,Hopanoids ,Analytical Chemistry ,chemistry.chemical_compound ,Triterpene ,Ic50 values ,Lichen ,Cytotoxicity ,Two-dimensional nuclear magnetic resonance spectroscopy - Abstract
One new hopane-type triterpene, indicuen (1), along with eight known compounds (2���9) were isolated from the n-hexane extract of the lichen Parmotrema indicum Hale. The chemical structures of isolated compounds were identified by interpretation of their spectroscopic data (1D, 2D NMR and HRESIMS) combined with DFT-NMR chemical shift calculations and subsequent assignment of DP4+ probabilities and by comparison with the literature. Indicuen represents for a rare hopane bearing a 1-carboxyethyl substituent at C-21 in lichens. Compounds 1���3 and 5���8 were evaluated for ��-glucosidase inhibition and cytotoxicity against K562 and HepG2 cancer cell lines. Compounds 1, 5 and 7 exhibited moderate ��-glucosidase inhibition with IC50 values of 201.1, 156.3 and 187.4 ��M, respectively. Compound 1 also showed weak cytotoxicity toward K562 cell line while others showed no activity.
- Published
- 2021
- Full Text
- View/download PDF
33. Rukamtenol, a new spiro compound isolated from
- Author
-
Cam Thi, Thai, Thuc-Huy, Duong, Nguyen Tien, Trung, Cam-Tu D, Phan, Quoc Vuong, Nguyen, Tuyen Le-Thanh, Nguyen, Kazuki, Watanabe, Tuoi Thi-Hong, Do, Thuy Ngoc, Huynh, and Hung, Tran
- Subjects
Molecular Structure ,Vietnam ,Antineoplastic Agents ,Spiro Compounds ,Flacourtia - Abstract
Chemical investigation of chloroform extract of
- Published
- 2020
34. Manilkzapotane, a novel dimeric alkylresorcinol derivative from the stem bark of
- Author
-
Thuc-Huy, Duong, Nguyen Tien, Trung, Cam-Tu D, Phan, Van-Kieu, Nguyen, Vassana, Musa, Thanatip, Ruksilp, Ngoc-Hong, Nguyen, Huu-Hung, Nguyen, and Jirapast, Sichaem
- Subjects
Manilkara ,Molecular Structure ,Plant Extracts ,Plant Bark - Abstract
A novel dimeric alkylresorcinol derivative, manilkzapotane (
- Published
- 2020
35. Ricicomin A, a new alkaloid from the leaves of
- Author
-
Nguyen Kim Tuyen, Pham, Thi Thao Linh, Tran, Thuc Huy, Duong, Nguyen Tien, Trung, Dang Cam Tu, Phan, Dinh Tri, Mai, Van Kieu, Nguyen, Bui Linh Chi, Huynh, Thi Anh Tuyet, Nguyen, Trong Duc, Tran, Thi Ngoc Mai, Tran, and Tan Phat, Nguyen
- Subjects
Plant Leaves ,Alkaloids ,Molecular Structure ,Plant Extracts ,Ricinus ,Humans - Abstract
From the leaves of
- Published
- 2020
36. A new diterpenoid from the leaves of
- Author
-
Thuc-Huy, Duong, Nguyen Tien, Trung, Cam-Tu Dang, Phan, Vu-Duy, Nguyen, Hoang-Chuong, Nguyen, Thi-Bich-Ngoc, Dao, Dinh-Tri, Mai, Nakorn, Niamnont, Thi-Ngoc-Mai, Tran, and Jirapast, Sichaem
- Subjects
Plant Leaves ,Phyllanthus ,Plant Extracts ,Diterpenes ,Cell Line - Abstract
A new diterpenoid, phyllane C (
- Published
- 2020
37. In-Depth Investigation of a Donor-Acceptor Interaction on the Heavy-Group-14@Group-13-Diyls in Transition-Metal Tetrylone Complexes: Structure, Bonding, and Property
- Author
-
Phan Tu Quy, Thanh Q. Bui, Huynh Thi Phuong Loan, Nguyen Tien Trung, Duong Tuan Quang, Tran Thi Ai My, Nguyen Thi Ai Nhung, Dang Tan Hiep, Nguyen Thi Thanh Hai, and Pham Van Tat
- Subjects
Materials science ,Bond strength ,General Chemical Engineering ,General Chemistry ,Article ,Metal ,Chemistry ,Crystallography ,Chemical bond ,Transition metal ,Polarizability ,Group (periodic table) ,visual_art ,Atom ,visual_art.visual_art_medium ,QD1-999 ,Quantum - Abstract
Stabilization for tetrylone complexes, which carry ylidone(0) ligands [(CO)5W-X (YCp*)2] (X = Ge, Sn, Pb; Y = B-Tl), has become an active theoretical research because of their promising application. Structure, bonding, and quantum properties of the transition-metal donor-acceptor complexes were theoretically investigated at the level of theory BP86 with several types of basis sets including SVP, TZVPP, and TZ2P+. The optimized structures reveal that all ligands X (YCp*)2 are strongly bonded in tilted modes to the metal fragment W(CO)5, and Cp* rings are mainly η5-bonded to atom X. DFT-based bonding analysis results in an implication that the stability of W-X bond strength primarily stems from the donation (CO)5W ← X(YCp*)2 formed by both σ- and π-bondings and the electrostatic interaction ΔE elstat. The W-X bond possesses a considerable polarizability toward atom X, and analysis on its hybridization is either sp2-characteristic or mainly p-characteristic. EDA-NOCV-based results further imply that the ligands XY perform as significant σ-donors but minor π-donors. The visual simulations of NOCV pairs and the deformation densities assemble a comprehensive summary on different components of the chemical bond via σ- and π-types in the complexes. This work contributes to the literature as an in-depth overview on predicted molecular structures and quantum parameters of the complexes [(CO)5W-X(YCp*)2] (X = Ge, Sn, Pb; Y = B-Tl), conducive to either further theoretical reference or extending experimental research.
- Published
- 2020
38. Evaluation of the Inhibitory Activities of COVID‐19 of Melaleuca cajuputi Oil Using Docking Simulation
- Author
-
Bui Thi Phuong Thuy, Nguyen Thi Xuan Dieu, Duong Tuan Quang, Tran Thi Ai My, Nguyen Thi Ai Nhung, Nguyen Thanh Triet, Le Trung Hieu, Nguyen Tien Trung, Vo Thanh Tung, Nguyen Thi Thanh Hai, Pham Van Tat, Tran Thai Hoa, Nguyen Van Hue, Huynh Thi Phuong Loan, and Tran Thi Van Anh
- Subjects
Protease ,food.ingredient ,Melaleuca cajuputi ,Guaiol ,medicine.medical_treatment ,Biological activity ,General Chemistry ,law.invention ,chemistry.chemical_compound ,Terpineol ,food ,chemistry ,Linalool ,Docking (molecular) ,law ,medicine ,Food science ,Essential oil - Abstract
GC-MS was applied to identify 24 main substances in Melaleuca cajuputi essential oil (TA) extracted from fresh cajeput leaves through steam distilling. The inhibitory capability of active compounds in the TA from Thua Thien Hue, Vietnam over the Angiotensin-Converting Enzyme 2 (ACE2) protein in human body - the host receptor for SARS-CoV-2 and the main protease (PDB6LU7) of the SARS-CoV-2 using docking simulation has been studied herein. The results indicate that the ACE2 and PDB6LU7 proteins were strongly inhibited by 10 out of 24 compounds accounting for 70.9% in the TA. The most powerful anticoronavirus activity is expressed in the order: Terpineol (TA2) ≈ Guaiol (TA5) ≈ Linalool (TA19) > Cineol (TA1) > β-Selinenol (TA3) > α-Eudesmol (TA4) > γ-Eudesmol (TA7). Interestingly, the synergistic interactions of these 10 substances of the TA exhibit excellent inhibition into the ACE2 and PDB6LU7 proteins. The docking results orient that the natural Melaleuca cajuputi essential oil is considered as a valuable resource for preventing SARS-CoV-2 invasion into human body.
- Published
- 2020
- Full Text
- View/download PDF
39. Atypical Lindenane-Type Sesquiterpenes from Lindera myrrha
- Author
-
Hoang-Dung Nguyen, Cam-Tu D. Phan, Mehdi A. Beniddir, Van-Kieu Nguyen, Van Giau Vo, Quynh-Loan Le, Pierre Le Pogam, Nguyen Tien Trung, and Thuc-Huy Duong
- Subjects
sesquiterpene ,Lindera ,Magnetic Resonance Spectroscopy ,Stereochemistry ,Pharmaceutical Science ,010402 general chemistry ,Sesquiterpene ,01 natural sciences ,Plant Roots ,Article ,Analytical Chemistry ,lcsh:QD241-441 ,chemistry.chemical_compound ,lindenane ,lcsh:Organic chemistry ,Drug Discovery ,Physical and Theoretical Chemistry ,Density Functional Theory ,biology ,Molecular Structure ,010405 organic chemistry ,Chemistry ,Organic Chemistry ,biology.organism_classification ,DFT-NMR ,0104 chemical sciences ,Chemistry (miscellaneous) ,Molecular Medicine ,Sesquiterpenes - Abstract
Two new lindenane sesquiterpenes were obtained from the roots of Lindera myrrha. These compounds were structurally elucidated by HRMS data, extensive NMR analyses, and comparison between experimental and theoretical 13C-NMR data. Myrrhalindenane A is the first monomeric seco-d lindenane displaying a non-rearranged, cyclohexanic C-ring. Myrrhalindenane B is the second occurrence of an angular lindenane-sesquiterpene related to a C6-C7 lactonization.
- Published
- 2020
40. Growth Pattern, Stability, and Properties of Complexes of C
- Author
-
Cam-Tu Dang, Phan, Nguyen Thi Ai, Nhung, and Nguyen Tien, Trung
- Subjects
Article - Abstract
This work is dedicated to theoretically investigate the formation process of C2H5OH···nCO2 (n = 1–5) complexes and to shed light on the nature of interactions formed under the variation of CO2 concentration. It is found that CO2 molecules tend to locate around the polarized −OH group to interact with the lone pairs of the O atom. The interaction of ethanol with three CO2 molecules (C2H5OH···3CO2) induces the most stable structure in the sequence considered. The atoms in molecules (AIM), NCIplot, and natural bond orbital (NBO) analyses point out that the Oethanol···CCO2 tetrel bond overcomes hydrogen, chalcogen, and CO2···CO2 tetrel-bonded interactions and mainly contributes to the strength of C2H5OH···nCO2 (n = 1–5) complexes. All intermolecular interactions in the examined complexes are weakly noncovalent, and their positive cooperativity is evaluated to be slightly weaker than that of CO2 pure systems. SAPT2+ and molecular electrostatic potential (MEP) calculations indicate that the electrostatic force is the main factor underlying the attractive interplay in the complexes of C2H5OH and CO2.
- Published
- 2020
41. Investigation into SARS-CoV-2 Resistance of Compounds in Garlic Essential Oil
- Author
-
Nguyen Tien Trung, Phan Tu Quy, Duong Tuan Quang, Lam K. Huynh, Nguyen Thi Ai Nhung, Le Trung Hieu, Nguyen Van Hue, Nguyen Thanh Triet, Huynh Thi Phuong Loan, Bui Thi Phuong Thuy, Tran Thi Van Anh, Tran Thai Hoa, Tran Thi Ai My, Nguyen Thi Thanh Hai, Pham Van Tat, and Vo Thanh Tung
- Subjects
chemistry.chemical_classification ,Protease ,Chemistry ,medicine.medical_treatment ,General Chemical Engineering ,food and beverages ,General Chemistry ,medicine.disease_cause ,Article ,Amino acid ,law.invention ,Addition/Correction ,lcsh:Chemistry ,Enzyme ,lcsh:QD1-999 ,Biochemistry ,Docking (molecular) ,law ,medicine ,Receptor ,Organosulfur compounds ,Essential oil ,Coronavirus - Abstract
Eighteen active substances, including 17 organosulfur compounds found in garlic essential oil (T), were identified by GC-MS analysis. For the first time, using the molecular docking technique, we report the inhibitory effect of the considered compounds on the host receptor angiotensin-converting enzyme 2 (ACE2) protein in the human body that leads to a crucial foundation about coronavirus resistance of individual compounds on the main protease (PDB6LU7) protein of SARS-CoV-2. The results show that the 17 organosulfur compounds, accounting for 99.4% contents of the garlic essential oil, have strong interactions with the amino acids of the ACE2 protein and the main protease PDB6LU7 of SARS-CoV-2. The strongest anticoronavirus activity is expressed in allyl disulfide and allyl trisulfide, which account for the highest content in the garlic essential oil (51.3%). Interestingly, docking results indicate the synergistic interactions of the 17 substances, which exhibit good inhibition of the ACE2 and PDB6LU7 proteins. The results suggest that the garlic essential oil is a valuable natural antivirus source, which contributes to preventing the invasion of coronavirus into the human body.
- Published
- 2020
42. Ricicomin A, a new alkaloid from the leaves of Ricinus communis Linn
- Author
-
Tan Phat Nguyen, Van Kieu Nguyen, Dinh Tri Mai, Nguyen Kim Tuyen Pham, Bui Linh Chi Huynh, Dang Cam Tu Phan, Trong D. Tran, Thi Thao Linh Tran, Thi Anh Tuyet Nguyen, Nguyen Tien Trung, Thuc-Huy Duong, and Thi Ngoc Mai Tran
- Subjects
biology ,010405 organic chemistry ,Chemistry ,Chemical structure ,Alkaloid ,Organic Chemistry ,Ricinus ,Euphorbiaceae ,Plant Science ,biology.organism_classification ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Analytical Chemistry ,HeLa ,010404 medicinal & biomolecular chemistry ,Genus ,Cell culture ,Human cancer - Abstract
From the leaves of Ricinus communis Linn., one new alkaloid, named ricicomin A (1) together with three known ones, ricinine (2), N-demethylricinine (3) and 4-[2-formyl-5-(methoxymethyl)-1H-pyrrol-1-yl]butanoic acid (4) were justified by repeated chromatographic methods. Their structures were determined by comprehensive IR, HR-ESI-MS and NMR analyses. Compound 4 was identified for the first time from the genus Ricinus. DFT-NMR chemical shift calculations and subsequent DP4+ probability methods were applied to confirm the chemical structure of 1. Compounds 1–3 did not display cytotoxic effect against three human cancer cell lines (MCF-7, HepG2 and HeLa) using SRB assay.
- Published
- 2020
- Full Text
- View/download PDF
43. A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
- Author
-
Phan Tu Quy, Thanh Q. Bui, Lam K. Huynh, Duong Tuan Quang, Vo Duy Nhan, Bui Thi Phuong Thuy, Nguyen Tien Trung, Huynh Thi Phuong Loan, Tran Thi Ai My, Nguyen Thi Ai Nhung, Pham Van Tat, and Duy Quang Dao
- Subjects
010405 organic chemistry ,Chemistry ,Ligand ,General Chemical Engineering ,General Chemistry ,010402 general chemistry ,01 natural sciences ,Bond-dissociation energy ,Molecular Docking Simulation ,0104 chemical sciences ,Metal ,chemistry.chemical_compound ,Crystallography ,Docking (molecular) ,visual_art ,visual_art.visual_art_medium ,Density functional theory ,Carbene ,Natural bond orbital - Abstract
Ribavirin and remdesivir have been preclinically reported as potential drugs for the treatment of SARS-CoV-2 infection, while light silver tetrylene complexes (NHEPh–AgCl and (NHEPh–AgCl)2 with E = C, Si, and Ge) have gained significant interest due to their promising applicability on the cytological scale. Firstly, the structures and bonding states of silver–tetrylene complexes (NHE–Ag) and bis-silver–tetrylene complexes (NHE–Ag-bis) were investigated using density functional theory (DFT) at the BP86 level with the def2-SVP and def2-TZVPP basis sets. Secondly, the inhibitory capabilities of the carbene complexes (NHC–Ag and NHC–Ag-bis) and the two potential drugs (ribavirin and remdesivir) on human-protein ACE2 and SARS-CoV-2 protease PDB6LU7 were evaluated using molecular docking simulation. The carbene ligand NHC bonds in a head-on configuration with AgCl and (AgCl)2, whereas, the other NHE (E = Si and Ge) tetrylene ligands bond in a side-on mode to the metal fragments. The bond dissociation energy (BDE) of the NHE–Ag bond in the complex families follows the order of NHC–Ag > NHSi–Ag > NHGe–Ag and NHSi–Ag-bis > NHGe–Ag-bis > NHC–Ag-bis. The natural bond orbital analysis implies that the [NHEPh→AgCl] and [(NHEPh)2→(AgCl)2] donations are derived mainly from the σ- and π-contributions of the ligands. The docking results indicate that both the ACE2 and PDB6LU7 proteins are strongly inhibited by silver–carbene NHC–Ag, bis-silver–carbene NHC–Ag-bis, ribavirin, and remdesivir with the docking score energy values varying from −17.5 to −16.5 kcal mol−1 and −16.9 to −16.6 kcal mol−1, respectively. The root-mean-square deviation values were recorded to be less than 2 A in all the calculated systems. Thus, the present study suggests that silver–carbene NHC–Ag and bis-silver–carbene NHC–Ag-bis complexes are potential candidates to inhibit ACE2 and PDB6LU7, and thus potentially conducive to prevent infection caused by the SARS-CoV-2 virus.
- Published
- 2020
- Full Text
- View/download PDF
44. Dear Colleagues! YOUR COMMENTS AND THOUGHTS ARE VERY VALUABLE
- Author
-
Zghair, Fadhil Sami, Zakaria, Saif Khalid, Smaisim, Ghassan Fadhil, D, Shiva Kumar H, Chetverikov, Alexander P., Lusciano, Francesco, Bulcsu Szekely, Merizgui Tahar, Shih-Wen Huang, Behrendt, Cezary, Tran, Tan, Wedad M. El-Kholy, PAVAN KUMAR, Al-Najjar, Hussein M. Taqi, Dnyaneshwar Namdev Jagtap, Mrad, Sonia, Hasanaj, Petrit, Zamani, Mohammad Reza, Trisna, Beni Adi, Nnarayan Billava, Dar, Basharat A. M., Al-Siyabi, Sultan, Ahmed, Firas, Edbey, Khaled, Amjed Lateef Jabbar, Parthapratim De, Beemnet Mengesha Kassahun, Nandkishor Meshram, Pundir, Ashok, K. Sinha, Apichit Maneengam, Adeeb, Eman R., Kalhoro, Abdul Naeem, Sulaiman, Mohammed, Faraci, Rocco, Al-Dulamey, Qusay, Hongduo Cao, Lashkari, Hassan, Nibras Husein Mhawesh, Sumana Gop, M. Senapathy, Abdelgadir, Ehsan Mohammed, Aldalimi, Wafaa, Gala, Francisco Javier, Niharika Keot, Ketchakmadze, Ivane, Munaf D. F. Al-Aseebee, Ishak Saat, Al-Rawi, Muna Sameer, Gulrux Zakirova, Noraldeen, Farooq, Khudhir, Zina Saab, Michał Ruszkowski, Refugio, Craig, Al-Qadi, Naim S., Mohammed, Hussain, Jaafer Hmood Eidi, Kadhum, Naser Jawad, P. Contreras, Masrour, Mohammed, Nishanbaev, Sabir, Al-Khresheh, Mohammad Hamad, Wassan M.Hussen, Yehya A. Salih, Hatem, Abeer Dakhil, Waggas Galib Atshan, Vaseashta, Ashok, Usmonova, Malika, Omayma A. Eldahshan, Fariborz Parandin, Sahli Youcef, Enas Hussein Ali, Cortés, Farid B., Thiago Santos, El-Shazly, Mohamed, Alwardi, Anwar, Sofián El-Astal, Huse Fatkić, Sheykhangafshe, Farzin Bagheri, Paweł Przybyłowicz, Nazaruddin Sinaga, Mustafa, Firas Mahmood, Doğan, Mustafa, Bresam, Sabah, Hooshang Rostamnejad Takleh, Deneva, Vera, Olutosin Ademola Otekunrin, Evens Emmanuel, Lordkipanidze, Revaz, Sihag, Parveen, Shaden M H Mubarak, Dafchahi, Fatemeh Hoodneh, Chebbi, Sabrine, Abdelhalim Zekry, Ramzan Ahmed, Dheyaa Falih Bannay, LEÓN-DUARTE, Gustavo Adolfo, Boukhari, Sofiane, Ma'moun M. Abu-Ayyad, Shadrack Katuu, Hasan, Mohammed Faez, Abhijit Mitra, Chinaza Godswill Awuchi, Hussein, Emad Kamil, Weiss, Michael Noah, Mkhelif, Adnan Z., Gafsi, Yosra, Avargani, Mina Karimi, Charos Toshtemirova, Mehdizadeh, Mohammad, Hassen, Jasim, Zaidan, Majeed Rashid, Wa'Il A. Godaymi Al-Tumah, Fazliddin Sodiqovich Jalilov, Kversøy, Kjartan Skogly, Espejo, Mariano Ruiz, Kittichai Jookjantra, Murawski, Krzysztof, Harito, Christian, Ramírez, Víctor Hugo San Martín, Zerrouki, Toufik, Rasouli, Hassan, Vega-Baudrit, José Roberto, Trindade, Carlos Alberto Matos, Azzad Bader, Almalikee, Hussein, Al-Khashman, Omar Ali, Sözbir, Bayram, Khan, Mohammad Jobair, Morell, Christophe, Ashkan Shekaari, González, Francisco Martínez, Portalone, Gustavo, Ziapour, Arash, Ketchakmadze, Dimitri, Yu-Da Lin, Ayala, Alejandro Pedro, Yañez, Osvaldo Andres, Iliyasu Musa Omoyine, Lazzarotto, Marcelo, Muhammad, Haroon, Shyi-Long Lee, Dr Umang Patel, Housaindokht, Mohammad Reza, Diaz-Sobac, Rafael, Izadyar, Mohammad, Geethu, Radhika, Gunajyoti Das, Antarip Halder, Semikov, Rostyslav, Gehan A Hegazy, Costa, João G., Arslan, Taner, Md Zahidul Islam, Pathak, Govind, Silva, Gabrielle, Torun, Gökhan, Nguyen, Thi Tran, Junnan Lu, Vinnarasi Saravanan, Nihar R Jena, Evangelisti, Luca, Vilanova-Costa, Cesar Augusto Sam Tiago, Martínez-Araya, Jorge Ignacio, Bozorgmehr, Mohammad Reza, Joaquin Barroso-Flores, Silva, Gabriel Da, Miandehy, Mohsen, Fahimi, Peyman, Miorelli, Jonathan, Whiteside, Alexander, Junhwan Kim, Nguyen Tien Trung, and Ol'ha O Brovarets
- Published
- 2020
- Full Text
- View/download PDF
45. Research Topic 'Proton Transfer Processes in Biological Reactions: A Computational Approach' Frontiers in Chemistry journal
- Author
-
Ol'ha O Brovarets, Hovorun, Dmytro Mykolayovych, Matta, Cherif F., Pérez-Sánchez, Horacio, Srivastava, Ruby, Ramírez, Víctor Hugo San Martín, Dr. Mohamed Mohamed Tolba Said, S. Tolosa Arroyo, Ashqer, Issam, Hidalgo, Antonio, Saade Abdalkareem Jasim, Saadoun Salimi, Sandipan Chakraborty, Sergienko, Ruslan, Bresam, Sabah, S. Feroz, S. Thamotharan, Meteab, Waleed Younus, Nishanbaev, Sabir, Chalanchi, Saber Mohammadi, S. M. Gorbatyuk, Sabnam S. Ullah, Sonne, Christian, Chebbi, Sabrine, Sadiq Kadhem Abidali, Saeid Ebrahimi, S. Askarian, S. Karimi, Sahli Youcef, Sahnawaz Alam, Zakaria, Saif Khalid, Banihani, Saleem Ali, Salifu Osman, Saiu, Salvatore, Almufti, Saman M., Sanat Ghosh, Sandor G Vari, Wategaonkar, Sanjay, Sarabjeet Kaur, Saranya Vasudevan, Santhosh George, Saravanan Kandasamy, Mamilov, Serge, Seada Hussen, Khomyak, Semen, Gaouar, Semir Bechir Suheil, Senapathy Marisennayya, Balci, Serdar, Kulikov, Sergey B., Leble, Sergey, Marchenko, Sergey, Ivanov, Sergey P, Burian, Sergii, Pustovit, Sergii, Vernygorodskyi, Sergii, Durand, Sergio, Sousa, Sérgio F., Okovytyy, Sergiy I, Senchurov, Sergiy, Dubovyk, Serhii, Holota, Serhii, Vasylevskyi, Serhii I., Blavatskyy, Serhiy, Vakal, Serhii, Shaden Khalifa, Shaaban Saad Elnesr, Shaden M H Mubarak, Rampino, Sergio, Shadrack Katuu, Stepanian, Stepan G., Rohman, Shahnaz, Portukhay, Sofiya, Evangelisti, Luca, Zand, Mohammad Reza Ahmadi, Wensheng Bian, De-Melo, Adriane Alexandre Machado, Hongduo Cao, González, Francisco Martínez, Oliynyk, Timothy, Tiwari, Ekta, Tiezza, Marco Dalla, Nguyen Tien Trung, To, Takahiro, Martínez-Araya, Jorge Ignacio, Vilanova-Costa, Cesar Augusto Sam Tiago, Martínez-Calderon, Miguel, Ortigosa, Pilar Martínez, Zerrouki, Toufik, Małgorzata Kiełczykowska, Lozovaya, Natalia, Zhyganiuk, Igor Viktorovich, Kouzari, Katerina, Małgorzata Gniewosz, Hudz, Nataliia, Moghani, Maryam Zeraati, Battino, Maurizio, Batista, Patrick Rodrigues, Ivashkiv, Iryna, Mashhour, Omar Farouk Al, Waggas Galib Atshan, Slman, Wafaa Jasim, Changwei Wang, Guendouzi Abdelkrim, G.E. Marin, Demo, Gabriel, Silva, Gabriel Da, Silva, Gabrielle, Zaychenko, Ganna, Gabrielis Kundrotas, Merino, Gabriel, Sobczyk, Garret Eugene, Gehan A Hegazy, Boyd, Georgina, Smaisim, Ghassan Fadhil, Mol, Gilbert Pushpam Sheeja, Ribaudo, Giovanni, Lorenzo, Giuseppe De, Skorobagatko, Gleb A., Baryshnikov, Gleb, Gokhan Torun, and Torun, Gökhan
- Published
- 2020
- Full Text
- View/download PDF
46. A study on structure and property of two complexes involving platinum(II), eugenol and 8-hydroxyquinoline derivatives
- Author
-
Nguyen Thi Thanh Chi, Truong Thi Cam Mai, Nguyen Tien Trung, and Phan Dang Cam Tu
- Subjects
Eugenol ,chemistry.chemical_compound ,010405 organic chemistry ,Chemistry ,Polymer chemistry ,chemistry.chemical_element ,8-Hydroxyquinoline ,Density functional theory ,010402 general chemistry ,Platinum ,01 natural sciences ,0104 chemical sciences - Published
- 2018
47. Transformation between Hexagonal Prism and Antiprism of the Singly and Doubly Cr-Doped Ge
- Author
-
Hung Tan, Pham, Cam-Tu Phan, Dang, Nguyen Tien, Trung, and Vu Thi, Ngan
- Abstract
Structural transformation is a unique characteristic of atomic clusters, but it turns out very different from cluster to cluster. This theoretical study proves that the isomeric transformation between hexagonal prism and hexagonal antiprism is found for the doubly doped Cr
- Published
- 2019
48. Insight into the adsorption of chloramphenicol on a vermiculite surface
- Author
-
Ana V. Dordio, Nguyen Tien Trung, Minh Tho Nguyen, Nguyen Ngoc Tri, and Alfredo J. Palace Carvalho
- Subjects
Period (periodic table) ,Chemistry ,Hydrogen bond ,Chloramphenicol ,General Physics and Astronomy ,02 engineering and technology ,010501 environmental sciences ,Vermiculite ,021001 nanoscience & nanotechnology ,Electrostatics ,01 natural sciences ,Adsorption ,Chemical engineering ,Chemisorption ,medicine ,Physical and Theoretical Chemistry ,0210 nano-technology ,Antibiotic Drugs ,0105 earth and related environmental sciences ,medicine.drug - Abstract
Four stable configurations were found upon adsorption of the chloramphenicol on a period slab model of the vermiculite surface, using the PBE and C09-vdW functionals in a projector-augmented wave (PAW) method approach. The adsorption is a strong chemisorption process, characterized by an adsorption energy of −106.5 kcal mol−1 at the most stable configuration. Stability of configurations contributed mainly by Mg⋯O/Cl attractive electrostatic interactions and C/O H⋯O hydrogen bonds. It is remarkable that the vermiculite is found to be a solid material with good potential to be used for adsorption and consequent removal of this type of antibiotic drugs.
- Published
- 2018
49. Further terpenoids from Vitex negundo L. growing in Vietnam
- Author
-
Thi-Hoai-Thu Nguyen, Thuc-Huy Duong, Nguyen Tien Trung, Thi-Hong-Tuoi Do, Dang-Cam-Tu Phan, Van-Giau Vo, Thi-Phuong Nguyen, and Ngoc-Hong Nguyen
- Subjects
Labdane-type diterpenoid ,Vitex negundo ,biology ,Stereochemistry ,Sclareol ,Vitexnegundin ,Vitex negundo L ,General Chemistry ,biology.organism_classification ,Terpenoid ,Chemistry ,chemistry.chemical_compound ,chemistry ,Penduletin ,Vitedoin B ,Ic50 values ,DP4 ,Cytotoxicity ,QD1-999 ,Two-dimensional nuclear magnetic resonance spectroscopy - Abstract
A new labdane-type diterpenoid, 9-epi-vitexnegundin (1), was isolated from the leaves of Vitex negundo L. together with seven known compounds: 8,13-diepi-manoyl oxide (2), 8-epi-sclareol (3), sclareol (4), 9,13-epoxy-labd-14-ene (5), vitedoin B (6), argyol (7), and predicularis-lactone (8). The chemical structures were elucidated by analysis of spectroscopic data and comparison with published NMR data. The DP4+ probability method was used to determine the relative stereochemistry of 9-epi-vitexnegundin. Complete NMR assignments of compound 2 were determined, revising the previously-reported NMR data for this compound. The stereochemistry of 9,13-epoxy-labd-14-ene (5) was elucidated for the first time, based on NOESY correlations. All isolated compounds 1–8 were evaluated for cytotoxicity against the K562 cell line, as were vitexnegundin (9), vitexilactone (10), vitetrifolin D (11), 13-hydroxy-5(10), 14-halimadien-6-one (12), artemetin (13), vitexicarpin (14), penduletin (15). Compounds 10–15 exhibited moderate cytotoxicity, with IC50 values in the range 15.7–79.8 µM.
- Published
- 2021
50. A Benzothiazolium-derived Colorimetric and Fluorescent Chemosensor for Detection of Hg2+ Ions
- Author
-
Vo Vien, Duong Tuan Quang, Nguyen Thi Ai Nhung, Nguyen Khoa Hien, Nguyen Tien Trung, Nguyen Chi Bao, Nguyen Duc Cuong, Doan Thanh Nhan, and Dinh Quy Huong
- Subjects
Detection limit ,Atoms in molecules ,Inorganic chemistry ,chemistry.chemical_element ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,Fluorescence ,0104 chemical sciences ,Mercury (element) ,Ion ,chemistry ,0210 nano-technology - Abstract
A benzothiazolium-derived colorimetric and fluorescent chemosensor (L) for mercury ions has been prepared. The detection limits of the colorimetric and fluorescent method are 15.3 and 11.8 ppb, respectively, much lower than the reported chemosensors based on similar derivatives of benzothiazolium. The optimized molecular structures, absorption and fluorescence characteristics of the chemosensor and its complex with mercury ions were performed using calculations at the B3LYP/LanL2DZ level of theory, in combination with Atoms in Molecules and Natural Bond Orbitals analyses.
- Published
- 2017
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.