4 results on '"Ranville, James F."'
Search Results
2. EFFECT OF AGE ON ACUTE TOXICITY OF CADMIUM, COPPER, NICKEL, AND ZINC IN INDIVIDUAL-METAL EXPOSURES TO DAPHNIA MAGNA NEONATES
- Author
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Traudt, Elizabeth M., Ranville, James F., and Meyer, Joseph S.
- Subjects
Lethal Dose 50 ,Aging ,Zinc ,Daphnia ,Nickel ,Metals, Heavy ,Toxicity Tests ,Animals ,Article ,Copper ,Water Pollutants, Chemical ,Cadmium - Abstract
In previous studies, variability was high among replicate acute cadmium (Cd) Daphnia magna lethality tests (e.g.,10-fold range of median effect concentrations [EC50s]), less among zinc (Zn) tests, and relatively low for copper (Cu) and nickel (Ni) tests. Although the US Environmental Protection Agency's (USEPA's) protocol includes starting toxicity tests with neonates less than 24 h old, the authors hypothesized that age-related differences in sensitivity to metals might occur even within that relatively narrow age range. Daphnia magna neonates were collected during 3 age windows (0-4 h, 10-14 h, and 20-24 h old) and immediately exposed to each of the 4 metals for 48 h using the standard USEPA protocol. In repeated sets of tests during different weeks, the Cd EC50 of the youngest neonates was approximately 10-fold greater than the EC50 of the oldest neonates (i.e., Cd was less toxic to the youngest neonates) and the EC50 of neonates aged 10 h to 14 h was intermediate. Age-related differences were negligible in Cu, Ni, and Zn tests. Therefore, variability in toxicity of Cd may partly be caused by temporal variability in neonate age at the start of toxicity tests. Decreasing the age range of D. magna used in toxicity tests could help to improve the accuracy and precision of toxicity models, particularly for metal mixtures. Environ Toxicol Chem 2017;36:113-119. © 2016 SETAC.
- Published
- 2016
3. Solubility of nano-zinc oxide in environmentally and biologically important matrices
- Author
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Reed, Robert B., Ladner, David A., Higgins, Christopher P., Westerhoff, Paul, and Ranville, James F.
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Solubility ,Surface Properties ,Nanoparticles ,Environment ,Particle Size ,Zinc Oxide ,Article ,Water Pollutants, Chemical - Abstract
Increasing manufacture and use of engineered nanoparticles (NPs) is leading to a greater probability for release of ENPs into the environment and exposure to organisms. In particular, zinc oxide (ZnO) is toxic, although it is unclear whether this toxicity is due to the zinc oxide nanoparticles (ZnO), dissolution to Zn2+, or some combination thereof. The goal of this study was to determine the relative solubilites of both commercially available and in-house synthesized ZnO in matrices used for environmental fate and transport or biological toxicity studies. Dissolution of ZnO was observed in nanopure water (7.18– 7.40 mg/L dissolved Zn, as measured by filtration) and Roswell Park Memorial Institute medium (RPMI-1640) (~5 mg/L), but much more dissolution was observed in Dulbecco’s Modified Eagle’s Medium (DMEM), where the dissolved Zn concentration exceeded 34 mg/L. Moderately hard water exhibited low zinc solubility, likely due to precipitation of a zinc carbonate solid phase. Precipitation of a zinc-containing solid phase in RPMI also appeared to limit zinc solubility. Equilibrium conditions with respect to ZnO solubility were not apparent in these matrices, even after more than 1,000 h of dissolution. These results suggest that solution chemistry exerts a strong influence on ZnO dissolution and can result in limits on zinc solubility due to precipitation of less soluble solid phases.
- Published
- 2012
4. Potential scenarios for nanomaterial release and subsequent alteration in the environment
- Author
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Nowack, Bernd, Ranville, James F., Diamond, Stephen, Gallego-Urrea, Julian A., Metcalfe, Chris, Rose, Jérôme, Horne, Nina, Koelmans, Albert A., Klaine, Stephen J., Swiss Federal Laboratories for Materials Testing and Research (EMPA), Gouvernement suisse, Centre européen de recherche et d'enseignement des géosciences de l'environnement (CEREGE), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Collège de France (CdF)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Collège de France (CdF (institution))-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Recherche Agronomique (INRA), and Institut de Recherche pour le Développement (IRD)-Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Collège de France (CdF (institution))-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
titanium-dioxide ,Aquatic Ecology and Water Quality Management ,silver nanoparticles ,WIMEK ,exposure assessment ,Fate ,engineered nanoparticles ,manufactured nanoparticles ,Transport ,Aquatische Ecologie en Waterkwaliteitsbeheer ,in-vitro ,walled carbon nanotubes ,Nanomaterials-containing products ,Wageningen Marine Research ,nanosilver toxicity ,consumer products ,[SDE]Environmental Sciences ,Environmental transformation ,Nanoparticles ,aquatic environments ,Risk assessment - Abstract
International audience; The risks associated with exposure to engineered nanomaterials (ENM) will be determined in part by the processes that control their environmental fate and transformation. These processes act not only on ENM that might be released directly into the environment, but more importantly also on ENM in consumer products and those that have been released from the product. The environmental fate and transformation are likely to differ significantly for each of these cases. The ENM released from actual direct use or from nanomaterial-containing products are much more relevant for ecotoxicological studies and risk assessment than pristine ENM. Released ENM may have a greater or lesser environmental impact than the starting materials, depending on the transformation reactions and the material. Almost nothing is known about the environmental behavior and the effects of released and transformed ENM, although these are the materials that are actually present in the environment. Further research is needed to determine whether the release and transformation processes result in a similar or more diverse set of ENM and ultimately how this affects environmental behavior. This article addresses these questions, using four hypothetical case studies that cover a wide range of ENM, their direct use or product applications, and their likely fate in the environment. Furthermore, a more definitive classification scheme for ENM should be adopted that reflects their surface condition, which is a result of both industrial and environmental processes acting on the ENM. The authors conclude that it is not possible to assess the risks associated with the use of ENM by investigating only the pristine form of the ENM, without considering alterations and transformation processes. Environ. Toxicol. Chem. 2012;31:5059. (C) 2011 SETAC
- Published
- 2012
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