Search

Two hundred years (1750–1950) of earthen architecture represents an important period of construction in the central region of Portugal. Earthen architecture is usually built close to the coast or to rivers and placed in sandy ground. The impact of rising damp is a general problem and efflorescences are a common cause of damage decay. This problem was studied in a building with two types of earthen construction, adobe masonry walls and formed masonry walls. The aim of this research was to characterise the conditions for the appearance and phase transitions of thénardite and mirabilite, and determine how to prevent progression of salt effects in the two types of wall to support future conservation measures. Laboratory capillarity and porosimetry tests with dolomitic air lime mortar and hygrothermal monitoring were pursued along with in situ tests. Visual assessment showed that the progression of salts depends on the composition of the earthen materials. To understand these differences, all crystalline solid phases were analysed by powder X-ray diffraction, and building interior hygrothermal conditions were monitored. An investigation into the influence of surface lime water painting and sacrificial mortar application on the crystallisation of sodium sulfates concluded that these also depend on the wall's composition. Data allowed us to conclude that inside the building the temperature and humidity [relative humidity (RH = 100 pw/p°w > 70)] conditions led to the adobe breakdown by the fast conversion from thénardite to mirabilite. Therefore, contact with wet atmospheres should be avoided and interior hygrothermal conditions should be controlled. Laboratory and in situ tests showed that the environmental conditions of the spaces had effects on the results. The results contribute to understanding of the salt progression and pattern of decay, as well as supporting future recommendations for building conservation, based on the identification of environmental conditions proper to their occurrence.

Este texto relata uma experiência que versa sobre o desenvolvimento das ações do curso de extensão O Teatro como Componente Curricular e a Aprendizagem Cooperativa no Contexto das Ações do Programa Focco, realizado por um grupo de bolsistas do Programa de Formação de Células Cooperativa de Aprendizagem (FOCCO) da Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado implementado pelo Câmpus Universitário do Médio Araguaia Dom Pedro Casaldáliga. Tendo como objetivo apresentar estratégias para o fortalecimento das células de aprendizagem cooperativa (grupos de estudos) sob a compreensão de que a organização das atividades que cercam o teatro é compatível com os princípios metodológicos do Programa FOCCO a partir do desenvolvimento das habilidades para trabalhar em grupo e trocar experiências entre aluno-aluno-professor-aluno. E assim, reconhecer a importância do protagonismo estudantil por meio do processo de construção de políticas educacionais. Esse curso é oferecido na modalidade ensino remoto, com encontros virtuais pela plataforma Google Meet, discussões em um grupo de WhatsApp e o compartilhamento de material de leitura e via Facebook, Instagram e Youtube. Para o desenvolvimento desse artigo recorremos aos princípios da pesquisa-ação sob viés da metodologia qualitativa a partir do uso de entrevistas, aplicação de formulários online e outras fontes documentais. Adotamos como referencial teórico as concepções dos autores Arroyo (2013), Candau (2011), Vygotsky (1999) Courtney, R. (1980) entre outros. Enquanto resultado podemos sinalizar que há uma aceitação por parte da maioria dos cursistas que de fato o teatro é um recurso metodológico estratégico para o desenvolvimento de práticas de ensino, sobretudo no que se refere ao desenvolvimento das habilidades para o trabalho em equipe e também da comunicação oral e corporal. Há também uma indicação que o teatro deve ser incorporado ao currículo escolar como uma disciplina ou ao menos como sendo conteúdo obrigatório sob a lógica de ser tema transversal ou interdisciplinar.

A previously unreported tetragonal phase has been discovered in a epitaxially strained GdMnO3 thin films deposited on (001)-oriented SrTiO3 substrates by radio frequency (RF) magnetron sputtering. The tetragonal axis of the films grown up to a 35 nm thickness is perpendicular to the film surface and the basal lattice parameters are imposed by the cubic structure of the substrate. Furthermore, the emergence of a spontaneous electric polarization below ~32 K points to the stabilization of an improper ferroelectric phase at low temperatures, which is not observed in bulk GdMnO3. This work shows how strain engineering can be used to tailor the structure and properties of strongly correlated oxides., Tis work was supported by national funds through the Portuguese Foundation for Science and Technology (FCT/MEC) and when appropriate co-fnanced by FEDER under PT2020 Partnership Agreement: Grant: SFRH/ BPD/80663/2011 and SFRH/BPD/92896/2013. Projects: IFIMUP-IN: Norte-070124-FEDER-000070; NECL: NORTE-01-0145-FEDER-022096, UID/NAN/50024/2019 and CICECO-AIM: POCI/01/0145-FEDER-007679, UID/CTM/50011/2013, PTDC/FIS-NAN/0533/2012,CERN/FIS/NUC/0004/2015, UID/FIS/04650/2013.

Este texto é parte dos resultados de uma pesquisa realizada sobre os elementos históricos que constituem o processo de formação do município de Porto Alegre do Norte, localizado na região nordeste do estado de Mato Grosso, também denominada de Microrregião Norte Araguaia. Ressalvamos que essa pesquisa possibilitou uma melhor compreensão acerca dos artifícios que compõem a dinâmica de reocupação de terra na região. Sendo assim, o nosso texto tem como função destacar os conflitos e as estratégias de luta dos posseiros, frente às ameaças e violências praticadas pelos fazendeiros na disputa pela posse da terra. Através desse estudo pôde-se perceber que esses conflitos de terra foram um longo e doloroso processo para os posseiros, que na época, habitavam a região, hoje conhecida como Porto Alegre do Norte. Lugar esse onde os posseiros enfrentaram diversos desafios, desde os conflitos com os fazendeiros e com os povos indígenas que habitavam a região.Palavras chave: Memória. Conflitos de Terra. Cultura.

GdMnO3 epitaxial thin films were deposited onto (110)-oriented SrTiO3 substrates by RF magnetron sputtering. The structure, microstructure, dielectric and magnetic properties were investigated in detail. The XRD results revealed that the GdMnO3 thin films exhibit an epitaxial strained orthorhombic symmetry and grow preferably in off-plane (001) orientation, wherein the basal lattice parameters are strained by the substrate lattice. A dielectric relaxation process was ascertained, whose activation energy is sensitive to the magnetic phase transitions, occurring at 41 K and at 20 K, respectively. The canted nature of the low temperature magnetic phase is discussed.

Background/Aims: Osteoporosis is a bone metabolic disease that affects mostly post-menopausal women. There has been shown that vitamin K (VK) supplementation during menopause may decrease bone loss as well as risk of bone breaking. Aiming to clarify the beneficial role of VK in bone metabolism during menopause, we investigated mineral metabolism and bone ultrastructure of ovariectomized (OVX) mice. Methods: To determine the effects chronic use of VK in bone structure and mineral metabolism in OVX mice, we used several methods, such as DXA, µCTScan, and SEM as well as biomolecular techniques, such as ELISA and qRT-PCR. In addition, complete analysis of serum hormonal and other molecules associated to bone and lipid metabolism were evaluated overview the effects of VK in menopause murine model. Results: VK treatment significantly affects Pi metabolism independently of OVX, changing Pi plasma, urinary output, balance, and Pi bone mass. Interestingly, VK also increased VLDL in mice independently of castration. In addition, VK increased compact bone mass in OVX mice when we evaluated it by DXA, histomorphometry, µCTScanning. VK increased bone formation markers, osteocalcin, HYP- osteocalcin, and AP whereas it decreased bone resorption markers, such as urinary DPD/creatinine ratio and plasmatic TRAP. Surprisingly, SEM images revealed that VK treatment led to amelioration of microfractures observed in OVX untreated controls. In addition, SHAM operated VK treated mice exhibited higher number of migrating osteoblasts and in situ secretion of AP. OVX led to decreased to in situ secretion of AP that was restored by VK treatment. Moreover, VK treatment increased mRNA expression of bone Calbindin 28KDa independently of OVX. Conclusion: VK treatment in OVX mice exhibited beneficial effects on bone ultrastructure, mostly by altering osteoblastic function and secretion of organic bone matrix. Therefore, VK could be useful to treat osteopenic/osteoporotic patients.

We report on the synthesis of free-standing ZnO nanoparticles (NPs) and ZnO NPs-decorated multiwalled carbon nanotubes (MWCNTs) via nonhydrolytic sol–gel (NHSG) routes. The role of the hydrates in the zinc precursor on the structure and surface termination of ZnO NPs via NHSG routes has already been reported in our earlier study. In the present work, the synthesis has been carried out in ambient air without using a glovebox, whereupon the effects of the synthesis temperature have been studied systematically. The structure, morphology, and optical properties of the free-standing ZnO-NPs are compared with those of the carbon nanotube-based nanocomposites, ZnO:MWCNTs, synthesized under identical conditions. The observed efficient and broad luminescence covering the entire visible spectrum points toward the high potential of the hybrid nanocomposites in optoelectronic and photovoltaic applications.

The structures of two newly discovered C70 high-pressure polymerized phases are described in a common basis. Both structures involve anti-parallel displacements of basal compact layers occurring, for each structure, along a particular unit cell axis. These displacements are crucial in the establishment of intermolecular covalent bonds and, thus, in the formation of the new phases. Pressure-temperature conditions for the synthesis of both phases are also described.

Resumo: Este trabalho tem como objetivo demonstrar o contexto histórico do Programa Parceladas na região do Araguaia, bem como verificar as contribuições do Programa Parceladas na formação inicial dos egressos do curso de Matemática. Para isso, analisamos documentos dos cursos de graduação em Matemática ofertados no período de 2003 a 2011. Os documentos selecionados foram: as ementas do projeto político pedagógico; relatório de autorização e processo de reconhecimento dos cursos; os planos de aula dos professores que ministraram aulas nas disciplinas de Educação Matemática e o questionário aplicado aos alunos egressos dessas turmas. Os resultados encontrados possibilitaram identificar o processo de consolidação do Programa Parceladas.Palavras-chave: Programa Parceladas; Araguaia; Formação inicial.

In the framework of two national research projects (ORGANOSOL and CN-linkAIR), fine particulate matter (PM2.5) was sampled for 17 months at an urban location in the Western European Coast. The PM2.5 samples were analyzed for organic carbon (OC), water-soluble organic carbon (WSOC), elemental carbon (EC), major water-soluble inorganic ions, mineralogical, and for the first time in this region, strontium isotope (87Sr/86Sr) composition. Organic matter dominates the identifiable urban PM2.5 mass, followed by secondary inorganic aerosols. The acquired data resulted also in a seasonal overview of the carbonaceous and inorganic aerosol composition, with an important contribution from primary biomass burning and secondary formation processes in colder and warmer periods, respectively. The fossil-related primary EC seems to be continually present throughout the sampling period. The 87Sr/86Sr ratios were measured on both the labile and residual PM2.5 fractions as well as on the bulk PM2.5 samples. Regardless of the air mass origin, the residual fractions are more radiogenic (representative of a natural crustal dust source) than the labile fractions, whose 87Sr/86Sr ratios are comparable to that of seawater. The 87Sr/86Sr ratios and the mineralogical composition data further suggest that sea salt and mineral dust are important primary natural sources of fine aerosols throughout the sampling period.

The reaction of [MoO(2)Cl(2)(pypzEA)] (1) (pypzEA = ethyl[3-(pyridin-2-yl)-1H-pyrazol-1-yl]acetate) with water in a Teflon-lined stainless steel autoclave (100 °C) or in an open reflux system leads to the isolation of the molybdenum oxide/pyrazolylpyridine composite material [Mo(2)O(6)(HpypzA)] (2; HpypzA = [3-(pyridinium-2-yl)-1H-pyrazol-1-yl]acetate). The solid state structure of 2 was solved through single crystal and powder X-ray diffraction analyses in conjunction with information derived from FT-IR and (13)C CP MAS NMR spectroscopies and elemental analyses. In the asymmetric unit of 2, two crystallographically distinct Mo(6+) centers are bridged by a syn,syn-carboxylate group of HpypzA. The periodic repetition of these units along the a axis of the unit cell leads to the formation of a one-dimensional composite polymer, (∞)(1)[Mo(2)O(6)(HpypzA)]. The outstretched pyrazolylpyridine groups of adjacent polymers interdigitate to form a zipper-like motif, generating strong onset π-π contacts between adjacent rings of coordinated HpypzA molecules. The composite oxide 2 is a stable heterogeneous catalyst for liquid-phase olefin epoxidation.

Submitted by Diana Silva (dianasilva@ua.pt) on 2017-06-05T15:14:59Z No. of bitstreams: 1 Extended polymerization in ABC-stacked C-70 fullerite_10.1016j.carbon.2014.10.063.pdf: 864486 bytes, checksum: 90b52bf179c595a1be3c0952969ea75b (MD5) Approved for entry into archive by Diana Silva(dianasilva@ua.pt) on 2017-06-05T15:15:21Z (GMT) No. of bitstreams: 1 Extended polymerization in ABC-stacked C-70 fullerite_10.1016j.carbon.2014.10.063.pdf: 864486 bytes, checksum: 90b52bf179c595a1be3c0952969ea75b (MD5) Made available in DSpace on 2017-06-05T15:15:21Z (GMT). No. of bitstreams: 1 Extended polymerization in ABC-stacked C-70 fullerite_10.1016j.carbon.2014.10.063.pdf: 864486 bytes, checksum: 90b52bf179c595a1be3c0952969ea75b (MD5) Previous issue date: 2015

Submitted by Diana Silva (dianasilva@ua.pt) on 2017-06-05T13:55:31Z No. of bitstreams: 1 A new fullerene network phase obtained from C-70 at high-pressure and high-temperature_10.1002pssr.201510236.pdf: 470768 bytes, checksum: e3ba1d118907f79cab00cd43209613d6 (MD5) Approved for entry into archive by Diana Silva(dianasilva@ua.pt) on 2017-06-05T13:57:08Z (GMT) No. of bitstreams: 1 A new fullerene network phase obtained from C-70 at high-pressure and high-temperature_10.1002pssr.201510236.pdf: 470768 bytes, checksum: e3ba1d118907f79cab00cd43209613d6 (MD5) Made available in DSpace on 2017-06-05T13:57:08Z (GMT). No. of bitstreams: 1 A new fullerene network phase obtained from C-70 at high-pressure and high-temperature_10.1002pssr.201510236.pdf: 470768 bytes, checksum: e3ba1d118907f79cab00cd43209613d6 (MD5) Previous issue date: 2015

Relatório de estágio de mestrado em Mediação Cultural e Literária, Este projeto, intitulado: QR-Code: Uma Janela Bidimensional ao Serviço do Turismo, tem como principais objetivos (i) refletir sobre o perfil do turista do Século XXI; (ii) identificar estratégias para promover o Mosteiro de São Martinho de Tibães enquanto local de interesse turístico; (iii) analisar o potencial da utilização de QR-Codes no Mosteiro de Tibães, focando aspetos como a autonomia do visitante, a disponibilização de conteúdos digitais variados e acessíveis, a interação do visitante com este lugar de memória; (iv) refletir sobre a implementação do sistema de QR-Codes, problemas, soluções e desafios para o futuro., The present project, entitled “QR-Code: A Bidimensional Window at the Service of Tourism”, set as its main goals: (i) a reflection on the profile of the 21st century tourist; (ii) the identification of strategies that may contribute to promote the Monastery of São Martinho de Tibães as a tourist attraction; (iii) a study of the potential of the QR-Code system in the Monastery of Tibães, focusing on aspects such as the autonomy of the tourist, the availability and accessibility of culturally diversified digital content, the interaction of the visitor with the place of memory; (iv) a reflection on the implementation of a QR-Code tourist circuit linked to digital storytelling content in the Monastery of Tibães: problems faced, solutions found and challenges for the future.

The study carried out in this work concerns the pectic polysaccharides of olive cell walls as present in olive pulp and that remained entrapped in the cellulosic residue after sequential extraction of the cell wall material (CWM) with imidazole, carbonate and KOH aqueous solutions. These polymers, obtained after neutralisation and dialysis of an aqueous suspension of the residue (sn-CR fraction), extracted with 4 M KOH, were arabinan-rich pectic polysaccharides. They accounted for 11–19% of the total pectic polysaccharides found in the olive pulp cell walls of fruits collected in two years and in three stages of ripening (green, cherry and black). The analysis by powder X-ray diffraction highlighted the existence, in all sn-CR fractions, of crystalline phases related with the presence of calcium-pectic polysaccharide complexes (CPPC) occurring in an amorphous carbohydrate network. The relative crystallinity of the CPPC varied linearly with the Ca 2+ /GalA molar ratio until a maximum of 0.57. Size-exclusion chromatography showed that sn-CR fractions possessed a bimodal molecular weight distribution. The lower molecular weight fraction of sn-CR ( M w = 70–135 kDa) was independent on the ripening stage of olive fruit, whereas the higher molecular weight fraction showed values of 1.1, 0.6–0.9 and 0.5–0.7 MDa, respectively, for green, cherry and black olives. Treatment of the sn-CR pectic polysaccharides with a 2 M imidazole solution disrupted the CPPC crystalline network showing the loss of low molecular weight galacturonan-rich material during dialysis (12–14 kDa cut off) and the decrease of molecular weight of the polymers to roughly half. These results allowed to infer the presence of oligogalacturonides held within cell walls by calcium ions and that the pectic polysaccharides of sn-CR fraction occurred in olive pulp cell walls as calcium bridged macrodimers.

Objetivo: Compreender a visão da equipe multidisciplinar perante a criança portadora de leucemia, em cuidado paliativo. Métodos: O presente estudo é de abordagem qualitativa, delineado pelo método de estudo de caso. Os sujeitos da pesquisa foram 17 profissionais de saúde que prestaram assistência direta à criança portadora de leucemia em cuidado paliativo. Resultados: Os resultados mostraram que, para os profissionais, o cuidado paliativo envolve um sofrimento por parte da família e do profissional, desperta muitas emoções na equipe. E que o cuidado humanizado deve ser realizado buscando o acolhimento tanto do paciente como da família, o conforto, o alívio da dor e dos sintomas, o apoio e a assistência à família. Conclusão: Conclui-se que o profissional de saúde cria vínculo com a criança em cuidado paliativo e, também, com sua família, o que é benéfico para o tratamento da criança. Descritores: Cuidados paliativos, Saúde da criança, Neoplasias, Leucemia, Emoções.

O cuidado paliativo desenvolve-se por meio de assistência multiprofissional com ações de suporte e conforto para a criança e sua família. O suporte se constitui do alívio do sofrimento pelo controle da dor e dos sintomas, bem como pelo apoio psicossocial e espiritual. Trata-se de um estudo de caso qualitativo que objetivou compreender a visão da equipe multidisciplinar perante a criança portadora de leucemia em cuidado paliativo, em uma instituição hospitalar de Belo Horizonte. Os sujeitos da pesquisa foram 17 profissionais de saúde da equipe de assistência direta à criança nesses cuidados. Os dados foram submetidos à técnica de análise de conteúdo. A experiência profissional em cuidado paliativo é intrínseca ao sucesso e à continuidade do tratamento do paciente. Verificou-se que os profissionais possuem pouca experiência nessa área e têm dificuldade em lidar com os sentimentos, se sentindo, às vezes, impossibilitados de agir mediante as angústias dos envolvidos e com a morte. Contudo, apesar de a área de atuação gerar sofrimento e angústia ao profissional, percebe-se que a equipe multiprofissional identifica-se e gosta da área o que é importante para a criança e sua família se sentirem seguros, respeitados e acolhidos pelos profissionais. Palliative care is developed through multi-professional assistance with actions to provide support and comfort for the children and their families. The support involves the alleviation of suffering by controlling the pain and its symptoms, as well as ensuring psychosocial and spiritual support. This is a qualitative case study which sought to understand the multidisciplinary view of the team vis-à-vis a child with leukemia in palliative care, in a hospital in Belo Horizonte. The subjects of research were 17 health professionals of the direct assistance team to the child receiving such care and the data were analyzed using the content analysis technique. The professional experience in palliative care is intrinsic to the success and continuity of the patient's care. It was found that the professionals have little experience in this area and have difficulty dealing with their emotions, and sometimes become unable to act when faced with the anguish of those involved and with death. However, despite the fact that the area of activity causes suffering and anguish to the professional, the multi-professional team still identifies with and likes the area, which is important for the children and their families to feel safe, respected and well cared for by the professionals.

Palliative care is developed through multi-professional assistance with actions to provide support and comfort for the children and their families. The support involves the alleviation of suffering by controlling the pain and its symptoms, as well as ensuring psychosocial and spiritual support. This is a qualitative case study which sought to understand the multidisciplinary view of the team vis-à-vis a child with leukemia in palliative care, in a hospital in Belo Horizonte. The subjects of research were 17 health professionals of the direct assistance team to the child receiving such care and the data were analyzed using the content analysis technique. The professional experience in palliative care is intrinsic to the success and continuity of the patient's care. It was found that the professionals have little experience in this area and have difficulty dealing with their emotions, and sometimes become unable to act when faced with the anguish of those involved and with death. However, despite the fact that the area of activity causes suffering and anguish to the professional, the multi-professional team still identifies with and likes the area, which is important for the children and their families to feel safe, respected and well cared for by the professionals.

Trabalho final de mestrado integrado em Medicina àrea científica de Cardiologia, apresentado á Faculdade de Medicina da Universidade de Coimbra INTRODUÇÃO: A diabetes mellitus (DM) é uma das maiores causas de morte a nível mundial, principalmente na decorrência de doenças cardiovasculares. Actualmente, sabe-se que além da diabetes, a tolerância diminuída à glicose e os demais dismetabolismos glucídicos, determinam um risco aumentado de Doença Arterial Coronária (DC) e eventos Coronários Agudos. Apesar da DM ser um conhecido preditor independente de mau prognóstico, a curto e a longo prazo, nos doentes com síndromas coronárias agudas (SCA), pouco se sabe sobre o impacto da DM de novo (DMN) e da pré-diabetes no prognóstico a longo prazo destes doentes. OBJECTIVO: Comparar a evolução após uma SCA, de 3 grupos de doentes com dismetabolismos glucídicos: diabéticos conhecidos, diabéticos de novo e doentes com pré-diabetes, determinando respectivamente a taxa de mortalidade e de eventos coronários. METODOLOGIA: Análise de uma base de dados da Unidade de Cuidados Intensivos Coronários do Serviço de Cardiologia dos Hospitais da Universidade de Coimbra, considerando os doentes com algum tipo de dismetabolismo glucídico (N=695) admitidos por SCA durante o período de Maio de 2004 a Dezembro de 2006 tendo sido posteriormente submetidos a seguimento clínico durante um ano. RESULTADOS: A proporção de doentes com antecedentes de hipertensão arterial, dislipidémia e história de enfarte do miocárdio prévio era significativamente maior nos doentes com DM prévia (DMP). Estes doentes apresentavam-se menos frequentemente em classe Killip I na admissão, apresentavam scores de risco TIMI significativamente mais altos e na coronáriografia apresentavam com maior frequência doença coronária de 3 vasos. Observaram-se diferenças significativas no que respeita à morbi-mortalidade no internamento e follow-up, entre os 3 grupos de doentes em estudo. A insuficiência cardíaca (IC) no follow-up ocorreu em maior percentagem nos doentes com DMP (11,8% vs 7,1% nos diabéticos de novo e 3,8% nos pré-diabéticos, p=0,04). As taxas de mortalidade ( no internamento e follow-up, respectivamente) foram igualmente maiores nos doentes com DMP (7.3% e 21.2%), seguidos dos doentes com DMN (4.7% e 14.8%). Relativamente às taxas de MACCE (major adverse cardiac and cerebrovascular events) não foram registadas diferenças entre os grupos. CONCLUSÃO: A DMN tal como a pré-diabetes demonstraram ter impacto negativo no prognóstico dos doentes com SCA, apresentando a primeira um impacto superior ao da segunda. Não superando, contudo, o conhecido impacto deletério da DMP. Mediante os resultados obtidos, conclui-se que, perante todo o doente com dismetabolismo glucídico, independentemente doutros factores de risco, é necessária uma acção médica agressiva e imediata de modo a alterar o prognóstico sombrio destes doentes. INTRODUCTION: Diabetes Mellitus (DM) is one of the leading causes of death in the developed world. Although DM affects several major organs and systems, reflecting its systemic nature, its morbidity and consequent mortality is particularly notorious in the cardiovascular domain. Nowadays it is a proven fact that decreased tolerance to glucose and the consequent metabolic deregulation leads to an increased risk of coronary artery disease and acute coronary events. Although DM is a known independent predictor of bad prognosis both in the short and long term in patients with acute coronary syndromes (ACS), little is known about the influence of both newly diagnosed DM and pre-diabetes in the long term prognosis of these patients. OBJECTIVES: To compare the evolution after one ACS in 3 separate groups of patients with deregulation of glucose metabolism: known background of DM, newly diagnosed DM and pre-diabetic condition. End variables consisted of mortality rate and severity and number of adverse coronary events METODOLOGY: Analysis of the intensive care coronary unit database of the Cardiology service of the University Hospital of Coimbra was carried. Patients admitted between May 2004 and December 2006 (N=695) with a diagnosis of ACS and consequent follow-up for the following year were considered. RESULTS: The proportion of patients with a history of arterial hypertension, dyslipidemia and prior myocardial infarction was significantly higher in patients with a known history of DM. Kilip I class was found less frequently at admission in these patients. TIMI risk scores were significantly higher alongside with increased prevalence of 3 artery coronary disease diagnosed through coronariography. Significant differences where found between the 3 groups concerning morbidity and mortality during inpatient stay and follow-up. Heart failure at follow-up occurred in higher percentage in the patients with known DM (11,8% vs 7,1% in patients with newly diagnosed DM and 3,8% in patients with pre-diabetes; p=0,004). The mortality rates (inpatient and follow-up, respectively) were comparable in patients with known DM (7.3% and 21.2%), followed by patients with newly diagnosed DM (4.7% e 14.8%). MACCE rates didn´t differ between groups. CONCLUSION: Both newly diagnosed DM and pre-diabetes demonstrate a negative influence in the prognosis of patients with ACS. The impact of the latter is not however as significant as the former. A known background of DM seems to influence prognosis more severely than any of the abovementioned conditions. Thus, an aggressive and expedite management of the clinical situation is needed in patients with glucose metabolic deregulation so that prognosis may be improved.

Mestrado em Gestão de Informação Hoje em dia, o grande desafio que os empreendedores enfrentam é o reconhecimento de oportunidades, num ambiente confuso e em constante mudança, onde a informação é muitas vezes contraditória e onde o tempo e o contexto são cruciais para a identificação de uma oportunidade passível de dar origem a um negócio de elevado potencial. Falar em bioempreendedorismo será analisar este conceito, quando a oportunidade de negócio surge nas áreas das ciências da vida. Contudo, para lançar uma empresa de biotecnologia não basta apenas ter espírito empreendedor, é necessário também um nível elevado de conhecimentos técnicos e científicos especializados, uma percepção das necessidades de mercados muito específicas e a capacidade de interagir com a comunidade académica e empresarial. Daqui advém a necessidade de os empreendedores terem de explorar o seu meio ambiente, estar à escuta, saber dialogar e informar, favorecendo em simultâneo a interactividade através da criação de uma rede de informação e conhecimento, formando assim um ambiente propício à inovação. A acção empreendedora pode, então, ser entendida mais como um fenómeno social do que propriamente individual. O presente trabalho apresenta um modelo conceptual para a criação de um espaço virtual, que tem em vista fomentar a construção e o crescimento de uma comunidade de prática on-line dirigida a especialistas em biotecnologia. Para uma compreensão das suas reais necessidades de informação, foi feita uma análise à rede do primeiro parque de biotecnologia do país, o Biocant Park e, em seguida, foram realizadas entrevistas, que serviram de suporte à conceptualização da plataforma. Este modelo conceptual ambiciona proporcionar um espaço colaborativo, de valor acrescentado para os seus utilizadores, disponibilizando informação útil, novidade e dinamismo. De igual forma, pretende aumentar o número de ligações da rede social de cada indivíduo e fomentar a colaboração e a cooperação inter-institucional, promovendo a geração de ideias, de transferência de tecnologia e de aprendizagem. A actividade iteractiva e interactiva de disseminação, troca e integração de conhecimento científico e tecnológico podem, desta forma, dar origem à identificação e desenvolvimento de novas oportunidades de negócio no campo da biotecnologia, através do aproveitamento do potencial e sinergias da rede. Nowadays, the great challenge that entrepreneurs faces is the recognition of opportunities in a confusing and constantly changing environment, where information is often contradictory and where time and context are crucial for the identification of an opportunity that could lead to a business with high potential. Talking about bioentrepreneurship will be to analyze this concept, when a business opportunity arises in life science areas. However, having entrepreneurial spirit is not enough to create a biotechnology company. It is needed to have a high level of technical and scientific expertise, an understanding of the needs of specific markets and the ability to interact with the academic and business community. Hence, entrepreneurs must explore their environment, be available to listen, knowing to dialogue and inform, simultaneously enhancing interactivity through an information and knowledge network, thus shaping a conducive environment to innovation. Therefore, the entrepreneurial action can be understood more as a social phenomenon than individual. The following essay presents a conceptual framework for the creation of a virtual space, which aims to encourage the construction and growth of an on-line community of practice intended for biotechnology specialists. For a comprehension of their real information needs, an analysis was made to Biocant Park, the first Portuguese biotechnology park, which served as support to the conceptualization of the platform. This conceptual model aims to provide a collaborative space, adding value to their users by providing useful information, newness and dynamism. Likewise, pretends to increase the number of connections of each individual social network, nourish inter-institutional collaboration and cooperation, promoting ideas generating, technology transfer and learning. The iteractive and interactive activities of dissemination, exchange and integration of scientific and technological knowledge thus lead to the identification and development of new business opportunities in biotechnology through the use of network´s potential and synergies.

The preparation of Ce doped BiVO 4 coatings on glass, by the thermal treatment of aqueous solutions containing a bismuth (III) ethylenediaminetetra-acetate chelate, vanadium (V) and cerium (III) species, is described here. The influence of cerium content on the colour properties of the coating was investigated. The coatings consist on morphological well-defined particles forming dense monolayers.

Introduction: The Achilles tendinopathy with tendon injuries are the third most common in the musculoskeletal system. New therapies have been proposed for the treatment of tendinopathy as Percutaneous Microelectrólisis (MEP ®). Objective: The aim of this study was to evaluate the effects of MEP ® on tendinopathy of Achilles. Method: This was a controlled clinical trial, randomized study. The sample comprised 20 patients with Achilles tendinopathy. The volunteers were randomly divided into two groups, control (G1) underwent conventional treatment protocol and experimental (G2) which was under the application of MEP. We made two visits per week for a month, totaling eight sessions. As evaluation method were used four questions from Visa-A questionnaire related to the functionality and exercise pratice. Data were analyzed using paired and independent T test . Results: The pain when walking down stairs has been observed a reduction in G1 (p