1. Acrosclerosis Associated with Vibration: an Electron Microscopic Study
- Author
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Ruffin S. Craig and Ken Hashimoto
- Subjects
Adult ,Male ,Vascular wall ,Pathology ,medicine.medical_specialty ,Histology ,Dermatology ,Vibration ,Pathology and Forensic Medicine ,law.invention ,Scleroderma, Localized ,Dermis ,law ,medicine ,Humans ,Peripheral Nerves ,Perivascular space ,Electron microscopic ,Skin ,Chemistry ,Raynaud Disease ,Anatomy ,Occupational Diseases ,Microscopy, Electron ,medicine.anatomical_structure ,Vacuolization ,Blood Vessels ,Collagen ,Endoneurium ,Electron microscope ,Axonal degeneration - Abstract
A case of typical vibration-induced acrosclerosis was studied with the electron microscope. In addition to increased collagenization of the dermis, vascular wall and perivascular spaces, a severe vacuolization and an increased number of lysosomes in the vascular endothelia cells were observed. In many peripheral nerves, axonal degeneration, demyelination and an extensive collagenization of peri- and endoneurium were observed. These changes appeared to be the organic basis for sclerosis and neuropathies of this condition.
- Published
- 1980
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