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The Nazca Ridge is a wide aseismic ridge subducting beneath the South American margin at latitude about 15°. The buoyancy of the thickened oceanic crust of the Nazca Ridge produces localized flat subduction influencing the geometry and the geological history of the whole area. With the aim of analysing the spatio-temporal evolution of the deformation and uplift/subsidence history of the lithosphere above the Nazca Ridge flat slab, we have started from the study of the geothermal structure of the upper plate. We have built a crustal section with a length of 1000 km that reaches a depth of about 130 km. The section runs from the top of the Nazca Ridge in the west to the Amazonian Basin in the east, progressively crossing the Peru-Chile trench, the East Pisco Basin and the Andean Cordillera. Thereafter we have elaborated a 2D geothermal model based on the crustal section. We have considered the whole lithosphere composed of two main geological units: (i) crystalline basement, (ii) sedimentary cover (including the whole lithostratigraphic succession). For each unit we have assigned the following parameters: thickness, density, heat production and thermal conductivity. Moreover, we have also taken into account the friction coefficient, the convergence rate of the plates, the heat flux of the Moho, and the slip rate of the megathrust. Model parameters have been set up in order to obtain the best simulation of the heat flow contribution due to the large reverse fault responsible for the coastal seismic event of November 12, 1996, with epicentre on the section trace. Using these parameters and applying an analytical methodology we have calculated isotherms and geotherms. The resulting model may provide an important contribution on the investigation of the effects of the Nazca Ridge subduction and the associated flat slab geometry on the tectonic evolution of the area.

Data of the 2-D Finite Element Modeling of the paper: Basilici et al. Active deformation and relief evolution in the western Lurestan region of the Zagros mountain belt: new insight from finite element modeling. Tectonics.

Data of the 2-D FEM of the paper: Basilici et al. 2020. Active deformation and relief evolution in the western Lurestan region of the Zagros mountain belt: new insight from finite element modeling. Tectonics.

In this paper we examine the seismicity of Montefeltro, an historical region of northern Apennines in central Italy. The analysis focuses on the seismic activity occurred in the period 2005-2017 to exploit the substantial improvement of the National Seismic Network (RSN) in the region. We collected P and S phases from 402 earthquakes for a total of about 7000 arrival times. Earthquakes were integrated with new pickings and relocated using the Hypoellipse code. The results show a sporadic, rather diffuse background seismicity marked by three small seismic sequences strongly clustered in time and space. The most important occurred in September-October 2005 (ML=3.2) and August-September 2006 (ML=3.7), in the neighbourhood of the towns of Macerata Feltria and Casteldelci, respectively. The spatio-temporal evolution of these main episodes highlights an energy release consistent with swarm-like activity. Another major feature of the seismicity pattern is represented by the occurrence of events even in the lower crust and in the upper mantle down to at least 50 km depth., In questo articolo viene esaminata la sismicità del Montefeltro, una regione storica dell’Appennino settentrionale, nell’Italia centrale. L’analisi si concentra sull’attività sismica avvenuta nel periodo 2005-2017, periodo durante il quale la Rete Sismica Nazionale (RSN) ha avuto nella regione un sostanziale miglioramento. Il data set selezionato consiste di 402 eventi per un totale di circa 7000 tempi di arrivo di fasi P e S. Gli eventi sono stati integrati con nuove letture e rilocalizzati con il programma Hypoellipse. I risultati mostrano una sismicità di fondo sporadica, sebbene piuttosto diffusa nell’area, contrassegnata da tre piccole sequenze fortemente clusterizzate nel tempo e nello spazio. Le più importanti sono avvenute nel settembre-ottobre 2005 (magnitudo massima ML=3.2) e nell’agosto-settembre 2006 (magnitudo massima ML=3.7), rispettivamente nei dintorni dei comuni di Macerata Feltria e Casteldelci. L’evoluzione spaziotemporale di questi due episodi evidenzia un rilascio di energia tipico degli sciami sismici. Un’altra peculiare caratteristica del pattern di sismicità è rappresentata dall’occorrenza di eventi anche nella crosta inferiore e nel mantello superiore fino a profondità di almeno 50 km.

We study a recently introduced base $b$ polynomial analog of Stern's diatomic sequence, which generalizes Stern polynomials of Klavar, Dilcher, Ericksen, Mansour, Stolarsky, and others. We lift some basic properties of base $2$ Stern polynomials to arbitrary base, and introduce a matrix characterization of Stern polynomials. By specializing, we recover some new number theoretic results about hyper $b$-ary partitions, which count partitions of $n$ into powers of $b$., 9 pages

Collana per la Casa Editrice Dei-Tipografia del Genio Civile Direttore di collana: Giancarlo Priori La collana ArchiTettonica vuole raccogliere una serie di libri con contenuti differenti ma che rientrano nel grande nome dell’architettura. Non dunque, uno spazio specialistico ma una collana inclusiva dove sarà possibile pubblicare, leggere e confrontare argomenti diversi che riconducono al sapere disciplinare unitario dell’architettura. Un progetto all’interno del quale sarà possibile trovare temi riguardanti la città, la sostenibilità, la riqualificazione, il restauro e il recupero, la storia ma anche la costruzione, la tecnologia e il progetto.

Figs. 1, 4, 5, 6, 7, 8 and 9 in this paper should have been printed in colour. They were printed in black and white in error but can be viewed in colour in the online version of the paper on ScienceDirect. The publisher apologises to the authors and to readers for the inconvenience caused.

We investigated inpatients with and without Type 2 diabetes mellitus, aged over 60 yr, to compare their vitamin D status and calcium homeostatic parameters.We studied 140 patients consecutively admitted to our Internal Medicine Unit during the year 2010 (61 from November to April, 79 from May to October). The sample encompassed 70 patients with and 70 without diabetes. At admission we measured serum calcium (Ca), phosphate (P), sodium (Na), potassium (K), creatinine (Cr), alkaline phosphatase total activity (AP), albumin adjusted serum calcium (Caalb adj), 25 hydroxy-vitamin D (25OHD), PTH, and 24-h urinary Na/Cr (uNa/Cr), K/Cr (uK/Cr), Ca/Cr (uCa/Cr), P/Cr (uP/Cr) ratios, and calcium excretion (Ca ex).25OHD levels of patients with and without diabetes did not significantly differ. In patients without diabetes recruited from November to April, 25OHD levels were significantly lower than those from May to October, whilst patients with diabetes did not show a significant seasonal variation. PTH had opposite non-significant seasonal variations, and negatively correlated with 25OHD in both groups of patients. This correlation was lost after adjusting for age and body mass index in patients with diabetes. These inpatients had higher serum P and lower uP/Cr, according to lower PTH. Their serum glucose negatively correlated with uCa/Cr and Ca ex, contrary to inpatients with other diseases. Instead, uCa/Cr and Ca ex correlated with uNa/Cr only in patients without diabetes.Inpatients with diabetes did differ from those with other disorders for vitamin D status and calcium-phosphate homeostatic mechanism.

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In this study, we evaluated the modifications of nasal function in type 1 diabetes (insulin-dependent diabetes mellitus [IDDM]) by active anterior rhinomanometry (AAR) to understand if involvement of the nasal nervous system and microcirculation could be detected in nasal mucosa.We studied 35 nonsmoking IDDM patients without diabetic complications, nasal pathology, or septal deviation. We measured serum levels of nitric oxide (NO) and nasal airway in three conditions: basal, supine, and after decongestion (phenylephrine hydrochloride 0.25 mg spray) by means of rhinomanometry, determining inspiratory total resistance and nasal airflow. The rhinomanometric results of the IDDM patients were compared with those of control normal subjects. In the IDDM patients, neuropathy was evaluated according to standardized procedures, including the vibration perception threshold test, cardiovascular autonomic tests, conduction velocity test, and fundoscopic examination.The NO serum level was significantly higher in IDDM patients (12.5 +/- 3.8) compared with normal controls (4.8 +/- 1.4). The AAR results showed that in IDDM patients, inspiratory total resistance in the basal (0.82 +/- 0.4 Pa/cm3) and supine (0.94 +/- 0.7 Pa/cm3) positions and after decongestion (0.59 +/- 0.2 Pa/cm3) were increased compared with the control group in three conditions (basal, 0.52 +/- 0.2 Pa/cm3; supine, 0.58 +/- 0.3 Pa/cm3; after decongestion, 0.48 +/- 0.2 Pa/cm3). After decongestion, there was a greater decrease in nasal resistance in diabetic patients than in normal subjects.Nasal function is involved in IDDM, rhinomanometry can also be considered an important test in the evaluation of this involvement in patients without other signs of diabetic neuropathy, and an increase in NO could partially explain these alterations.

In this article, we show that passage in SCID mice rendered a human CD4(+) T-cell line (CEM cells) highly susceptible to infection by macrophage-tropic (M-tropic) strains and primary clinical isolates of human immunodeficiency virus type 1 (HIV-1). This in vivo-acquired permissiveness of CEM cells was associated with the induction of a CD45RO+ phenotype as well as of some beta-chemokine receptors. Regulated upon activation, normal T-cell expressed and secreted chemokine entirely inhibited the ability of M-tropic HIV-1 strains to infect these cells. These findings may lead to new approaches in investigating in vivo the capacity of different HIV strains to exploit chemokine receptors in relation to the dynamics of the activation and/or differentiation state of human CD4(+) T cells.