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Background: For normally sighted readers, word neighborhood size (i.e., the total number of words that can be formed from a single word by changing only one letter) has a facilitator effect on word recognition. When reading with central field loss (CFL), however, individual letters may not be correctly identified, leading to possible misidentifications and a reverse neighborhood size effect. Here we investigate this inhibitory effect of word neighborhood size on reading performance and whether it is modulated by word predictability and reading proficiency. Methods: Nineteen patients with binocular CFL from 32 to 89 years old (mean ± SD = 75 ± 15) read short sentences presented with the self-paced reading paradigm. Accuracy and reading time were measured for each target word read, along with its predictability, i.e., its probability of occurrence following the two preceding words in the sentence using a trigram analysis. Linear mixed effects models were then fit to estimate the individual contributions of word neighborhood size, predictability, frequency and length on accuracy and reading time, while taking into account patients’ reading proficiency.Results: For the less proficient readers who quit reading on a daily basis, we found that the effect of neighborhood size was reversed compared to normal readers and of higher amplitude than the effect of frequency. Furthermore, this inhibitory effect is of greater amplitude (up to 50% decrease in reading speed) when a word is not easily predictable because its chances to occur after the two preceding words in a specific sentence are rather low.Conclusion: Severely impaired patients with CFL often quit reading on a daily basis because this task becomes simply too exhausting. Based on our results, we envision lexical text simplification as a new alternative to promote decisive rehabilitation in these patients. By increasing reading accessibility for those who struggle the most, text simplification might be used as an efficient readaptive tool and daily reading assistive technology, fostering overall reading ability and fluency through increased practice.

International audience; The objective of this work is to introduce text simplification as a potential reading aid to help improve the poor reading performance experienced by visually impaired individuals. As a first step, we explore what makes a text especially complex when read with low vision, by assessing the individual effect of three word properties (frequency, orthographic similarity and length) on reading speed in the presence of Central visual Field Loss (CFL). Individuals with bilateral CFL induced by macular diseases read pairs of French sentences displayed with the self-paced reading method. For each sentence pair, sentence n contained a target word matched with a synonym word of the same length included in sentence n+1. Reading time was recorded for each target word. Given the corpus we used, our results show that (1) word frequency has a significant effect on reading time (the more frequent the faster the reading speed) with larger amplitude (in the range of seconds) compared to normal vision; (2) word neighborhood size has a significant effect on reading time (the more neighbors the slower the reading speed), this effect being rather small in amplitude, but interestingly reversed compared to normal vision; (3) word length has no significant effect on reading time. Supporting the development of new and more effective assistive technology to help low vision is an important and timely issue, with massive potential implications for social and rehabilitation practices. The end goal of this project will be to use our findings to custom text simplification to this specific population and use it as an optimal and efficient reading aid.

International audience; The objective of this work is to introduce text simplification as a potential reading aid to help improve the poor reading performance experienced by visually impaired individuals. As a first step, we explore what makes a text especially complex when read with low vision, by assessing the individual effect of three word properties (frequency, orthographic similarity and length) on reading speed in the presence of Central visual Field Loss (CFL). Individuals with bilateral CFL induced by macular diseases read pairs of French sentences displayed with the self-paced reading method. For each sentence pair, sentence n contained a target word matched with a synonym word of the same length included in sentence n+1. Reading time was recorded for each target word. Given the corpus we used, our results show that (1) word frequency has a significant effect on reading time (the more frequent the faster the reading speed) with larger amplitude (in the range of seconds) compared to normal vision; (2) word neighborhood size has a significant effect on reading time (the more neighbors the slower the reading speed), this effect being rather small in amplitude, but interestingly reversed compared to normal vision; (3) word length has no significant effect on reading time. Supporting the development of new and more effective assistive technology to help low vision is an important and timely issue, with massive potential implications for social and rehabilitation practices. The end goal of this project will be to use our findings to custom text simplification to this specific population and use it as an optimal and efficient reading aid.

The objective of this work is to introduce text simplification as a potential reading aid to help improve the poor reading performance experienced by visually impaired individuals. As a first step, we explore what makes a text especially complex when read with low vision by assessing the individual effect of three word properties (frequency, orthographic similarity and length) on reading speed in the presence of Central visual Field Loss (CFL). Individuals with bilateral CFL induced by macular diseases read pairs of French sentences displayed with a self-paced reading method. For each sentence pair, sentence n contained a target word matched with a synonym word of the same length included in sentence n+1. Reading time was recorded for each target word. Given the corpus we used, our results show that (1) word frequency has a significant effect on reading time (the more frequent the faster the reading speed) with larger amplitude (in the range of seconds) compared to normal vision; (2) word neighborhood size has a significant effect on reading time (the more neighbors the slower the reading speed), this effect being rather small in amplitude, but interestingly reversed compared to normal vision; (3) word length has no significant effect on reading time. Supporting the development of new and more effective assistive technology to help low vision is an important and timely issue, with massive potential implications for social and rehabilitation practices. The end goal of this project will be to use our findings to custom text simplification to this specific population and use it as an optimal and efficient reading aid.

Thèse présentée sous la forme d'une "thèse article"; Objectives: Dichoptic movie viewing significantly improves visual acuity in amblyopia on children. Moreover, short-term occlusion of the amblyopic eye can transiently increase its contribution to binocular fusion after patch removal. In this study, we first asked whether passive dichoptic movie viewing could increase the visual function of subjects beyond the critical period. Secondly we tested if this effect could be enhanced by short-term monocular occlusion of the amblyopic eye.Materials and Methods: 17 subjects presenting fixed and functional amblyopia, aged from 9 to 67 yo, participated in this study. 10 subjects followed 6 sessions of 1.5 hour for 2 weeks of passive dichoptic movie viewing (non-patched group) and 7 subjects, prior to each of these sessions, had to wear an occluding patch of the amblyopic eye for two hours (patched group). Best-corrected visual acuity, monocular contrast sensitivity, interocular balance and stereoacuity were measured at baseline, at the outcome of the training and at a follow-up one month later.Results: For the non-patched group, mean amblyopic eye visual acuity significantly (p