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Biotibbi görüntüləmə üçün istifadə edilən hər hansı nüfuzedici şüalanmaya qoyulan əsas tələblər onun yayılmasının həndəsi cəhətdən proqnozlaşdırıla bilən olması, mühitdə zəifləmənin çox güclü olmaması və bu şüalanmanın canlı orqanizmə təsirinin mümkün qədər zərərsiz olmasıdır. Bu tələblər difraksiya ilə müəyyən edilən şüalanmanın istiqamətinin tələb olunan məkan ayırdetmə qabiliyyətinə uyğun olacağı tezliklərdə yerinə yetirilməlidir. Başqa sözlə, nüfuz edən radiasiyanın dalğa uzunluqları tədqiq olunan strukturla müqayisədə kiçik olmalıdır. Bütün bu tələblər ultrasəsin bədənin yumşaq toxumalarında yayılması ilə tam təmin edilir. Ultrasəs dalğaları hələ rentgen şüalarından əvvəl kəşf edilsə də, tibbdə xeyli sonralar - XX əsrin 50-ci illərində əvvəlcə mamalıqda, sonra isə təbabətin digər sahələrində istifadə edilmişdir. Bu diaqnostik metodun əsas üstünlükləri qeyri-invazivlik, yüksək vizuallaşdırma keyfiyyəti və nisbi istifadə rahatlığıdır. Tibbi ultrasəs görüntüləmə yüksək tezlikli səs dalğalarından istifadə edərək bədəndəki hər hansı bir orqan və ya toxumanın real vaxt rejimində vizuallaşdırılmasını təmin etmək məqsədi daşıyır. Müayinə zamanı alınan siqnallar diaqnostikaya kömək etmək üçün götürülməli, işlənməli və müəyyən edilməlidir. Ultrasəs yüksək tezlikli impulslarla bədənə ötürülür, bu dalğaların bəziləri udulur, bəziləri isə geri əks olunur. Əks olunan dalğalar ötürücü tərəfindən qəbul edilir və elektrik siqnallarına çevrilir. Həmin elektrik siqnalları rəqəmsal siqnala çevrilir və kompüter sistemindən keçir. Kompüter sistemi skan edilmiş strukturların görüntüsünü yaratmaq üçün arifmetik və məntiqi hesablamalardan istifadə edir. Ultrasəs, radioloji üsullarla yanaşı, instrumental diaqnostikanın ən vacib elementidir və tibbi fəaliyyətin demək olar ki, bütün sahələrində istifadə olunur. Hal-hazırda ultrasəs diaqnostikası və ya sonoqrafiya yalnız ayrı bir tibb ixtisası deyil, həm də öz alt ixtisasları, cari problemlər və meylləri olan müxtəlif tədqiqatlar üçün böyük bir sahədir. Ultrasəs diaqnostikasında dinamik parametrlərin ölçülməsi ürək-damar sisteminin öyrənilməsində də istifadə olunur. Bu cür ölçmələr Doppler effektinə əsaslanır və müasir ultrasəsdə hərəkət edən strukturların vizuallaşdırılması ilə birləşdirilir. Ultrasəs görüntüləmə hazırda bir çox sahələrdə istifadə olunur: planlaşdırılmış tədqiqat; təcili diaqnostika; monitorinq; əməliyyatdaxili diaqnostika; əməliyyatdan sonrakı tədqiqatlar; diaqnostik və terapevtik instrumental manipulyasiyaların (ponksiyonlar, biopsiyalar və s.) həyata keçirilməsinə nəzarət; skrininq. İnformasiya mənbəyi kimi USM təsviri ilə işləmək müsbət və mənfi cəhətlərə malikdir. Müsbət tərəfi, ultrasəs MRT və KT ilə müqayisədə nisbətən ucuz görüntüləmə üsuludur, portativdir və real vaxt rejimində informasiya əldə etmək imkanı təklif edir. Əsas mənfi cəhətləri ondan ibarətdir ki, görüntü əldəetmə operatordan asılıdır və yaxşı məlumat əldə etmək üçün (çox vaxt əhəmiyyətli) təlim tələb olunur. USM görüntüləmə KT və MRT-nin yüksək anatomik tərifini bölüşmür. Təsvirin görünüşü bioloji obyektə münasibətdə ötürücünün oriyentasiyası, siqnalın zəifləməsi və siqnalın kəsilməsi və akustik kölgələr səbəbindən çatışmayan məlumat daxil olmaqla amillərdən asılıdır. Ultrasəs 2D təsvirlərinin optimallaşdırılması üçün dərinlik (depth), fokus, zoom, qazanc, dinamik diapazon (kontrast) və.s parametrləri tənzimləmək lazımdır. Son ultrasəs sistemlərində bu parametrlər ekranda istənilən görüntü keyfiyyətini əldə etmək üçün sistem tərəfindən avtomatik təyin edilir və yaxud operator tərəfindən əl ilə tənzimlənir. Açar sözlər: Ultrasəs görüntüləmə metodu, təsvirlərinin optimallaşdırılması, görüntü parametrləri, dinamik diapazon, təsvir keyfiyyəti.

Intellectualization of production and processes is one of the applications of information technology and it is always of interest to develop and apply new methods. The creation and use of an intelligent transport system is considered one of the most important tasks in the field of automation. The article review is devoted to the development and operation of an intelligent control system for the safe movement of vehicles and other moving objects. The basic principles of ensuring road safety are given, the works, standards for the creation and development of transport systems are investigated, the architecture of an intelligent transport system is determined. A simplified top-level logical architecture of an intelligent transport system is presented, which includes task groups, as well as links between them and with external objects. And the physical model includes the functions of the logical architecture, classes, subsystems of processes and placement of places for the implementation of these functions. Classes include: passengers, centers, vehicles, equipment, and telecommunications facilities. The subsystems of the intelligent transport system and the tasks they cover are listed. An intelligent transport system as an integrator of modes of transport can improve the efficiency and safety of transport systems. Keywords: Intelligent transport system, security, architecture, standardization, simplified, information, new method.

Hal-hazırda tətbiq olunan skrininq və diaqnostika üsullarının daxilində saysız-hesabsız bir çox problem mövcuddur. Bundan əlavə, dünyada mövcud olan çox sayda xəstəlikləri müəyyən etmək üçün inanılmaz dərəcədə geniş çeşidli prosedurlardan istifadə olunur. Bu prosedurların diaqnostik imkanlarını təkmilləşdirmək, o cümlədən testin həssaslığını və spesifikliyini, obyektivliyini və qətiliyini artırmaq, testin dəyərini və invazivliyini azaltmaq, çoxsaylı diaqnostik metodları bir güclü alətlə əvəz etmək marağı ilə təmin edilmiş klinik prosedurlara ehtiyac var. Xərçənglər, viral və bakterial infeksiyalar, neyrodegenerativ və.s xəstəliklər daxil olmaqla bir sıra xəstəliklərin müəyyən edilməsi üçün diaqnostik tədbirləri təkmilləşdirmək üçün Raman spektroskopiyasından istifadəyə yönəlmiş ədəbiyyatda son dövrlərdə artım müşahidə olunur. Raman spektroskopiyası biomayelər, hüceyrələr və toxumalar kimi mürəkkəb bioloji nümunələrin kimyəvi tərkibini ölçə bilən güclü analitik texnikadır. Raman spektri nümunənin molekulyar barmaq izini təmsil edir və onun kimyəvi tərkibi ilə bağlı kəmiyyət məlumatı verir. Hüceyrələrdə və toxumalarda bir xəstəliyə səbəb ola bilən və ya səbəb ola bilən biokimyəvi dəyişikliklər Raman spektrlərində əhəmiyyətli dəyişikliklərə səbəb ola bilər. Raman spektroskopiyasının potensialı onun molekulyar səviyyədə belə biokimyəvi dəyişiklikləri aşkar etmək qabiliyyətindən irəli gəlir və buna görə də diaqnostika, proqnoz və ya yeni müalicə üsullarını qiymətləndirmək üçün istifadə edilə bilər. Raman spektroskopiyası son zamanlar xərçəngin erkən aşkarlanması, müxtəlif agentlərin dəriyə təsirinin monitorinqi və patogen mikroorqanizmlərin sürətli identifikasiyası kimi müxtəlif biotibbi məsələlərin həlli üçün ex vivo və in vivo olaraq tətbiq edilmişdir. Mədə xərçənginə adətən gec mərhələdə diaqnoz qoyulur və yüksək ölüm nisbətinə malikdir, halbuki mədə xərçənginin erkən aşkarlanması daha yaxşı proqnoz verə bilər. Mədə xərçənginin kliniki diaqnostikasında endoskopik diaqnostika, patoloji diaqnostika və tibbi təsvirlər adətən istifadə olunur və bu diaqnostika üsulları uzun diaqnoz müddətləri, ciddi travma və yüksək səhv mühakimə etmə mənfi cəhətlərinə malikdir və əsasən həkimlərin subyektiv təcrübəsinə əsaslanır. Nəticədə, sürətli, qeyri-invaziv, yüksək dəqiqlikli və həssas olan yeni mədə xərçəngi diaqnozu texnikasına çox ehtiyac var. Molekulyar vibrasiya spektroskopiyası üsulu olan Raman spektroskopiyası molekullardan barmaq izi məlumatı əldə etməklə müxtəlif maddələrin xüsusiyyətlərini və strukturlarını müəyyən edə bilir. Raman spektroskopiyası hazırda müxtəlif şişlərin diaqnostikasında istifadə olunur. Ənənəvi mədə xərçəngi diaqnostik üsulları uzun diaqnostik müddətlərdən, ağır travmalardan və yüksək yanlış diaqnozdan əziyyət çəkir və həkimlərin subyektiv təcrübəsinə əsaslanır. Raman spektroskopiyası monoxromatik işığın qeyri-elastik səpilməsi əsasında müxtəlif nümunələrin molekulyar izini müəyyən edən etiketsiz molekulyar vibrasiya spektroskopiyası üsuludur. Qeyri-dağıdıcı, sürətli və dəqiq aşkarlama üstünlüklərinə görə Raman spektroskopiyası yaxşı və bədxassəli şişlərin diferensasiyası, şişin alt tiplərinin təsnifatı və bölmə patologiyasının diaqnostikası üçün geniş şəkildə tədqiq edilmişdir. Əksər proqramlar üçün spektroskopik alətlər işıq və toxuma arasındakı qarşılıqlı təsirlərdən əldə edilən məlumatlar haqqında kəmiyyət məlumatı vermək üçün yüksək sürətli kompüterlərdən istifadə edir. Bu şəkildə, spektroskopiya ilə əldə edilən məlumatlar obyektiv qiymətləndirilə, müqayisə edilə və mənalı klinik məlumat təmin edilə bilər. Bu yazı Raman spektroskopiyasının tətbiqləri nəzərdən keçirilirmiş, xərçənginin in vivo və in vitro diaqnostikası, spektroskopiya məlumatlarının təhlili ilə əlaqəli metodologiya və texnikanın məhdudiyyətlərini təqdim edir. Açar sözlər: Raman spektroskopiya metodu, Raman səpilmə prinsipi, Mədə xərçənginin diaqnostikası, Endoskop texnikası, Fiber-optika.

Məqalədə Vətən üçün, onun bölünməzliyi üçün sinəsini tank və BTR-lərə sipər edən Vətən oğulları, qızları, 1990-cı il şəhidləri və onların Vətənin müdafiəsi uğrunda göstərdikləri mübarizə ,əzmkarlıq haqqında məlumat verilir. Yurduna, elinə sahib çıxan Vətən övladlarının “Qarabağı əldən vermərik”, “Ölərik bu yoldan dönmərik” şüarları ilə son nəfəslərini verdikləri qeyd olunur. Məqalə ən yeni dövr Azərbaycan tarixində iki əhəmiyyətli hadisənin - 1990-cı il 20 Yanvar hadisəsinin və 2020-cı il Vətən torpaqlari uğrunda gedən döyüşlərin təhlilinə həsr edilib. Burada Azərbaycanın müstəqilliyinin əvvəlində baş vermiş faciə və artıq müstəqillik qazanmış gənc Respublikanın milli ordusunun cəbhədə əldə etdiyi qələbə arasında müqayisələr aparılır. Açar sözlər: Vətən,Qarabağ, bölünməzlik, 20 Yanvar,tarix,şəhidlər,xalq,azadlıq

Thermal and one many thermocatalytic processes high temperature conditions is going This consider taking raw material first tubular in ovens certain temperature up to is heated. Some in processes the same as the tubular furnace at the time replace the reactor is doing In the oven placed serpentine of pipes beginning part raw material it heats up. Next in pipes cracking process goes. Raw material whom individual of hydrocarbons use when done unconverted raw material live reaction environment to give too favorable. Catalytic isomerization process of 50-65% isopentane from normal pentane is taken. 1-2% gas during the process hydrocarbons too doesn't buy N- pentanm non-isomerizable the part live again to the reactor when returned of isopentane to normal pentane according to it reaches 97-98%. According to the prepared model, the final indicator of the output of the target products (propylene + ethylene) and the output of these components relative to the total filling of the reactor were taken as optimality criteria during the process study. The essence of the recirculation method is that the mixture of reacting and non-reacting products enters the separator system after the reactor. Here they are separated from each other, and then the unreacted part is mixed with fresh raw materials and fed back into the reactor. In our case, only unreacted propane and ethane are given to recirculation, not all of the output products from the reactor. Because only they are converted into the intended products - propylene and ethane - by primary reactions. if a part of the devices included in the complex is not taken into account in the mathematical modeling and optimization of the process, the obtained value of the optimality criterion will be wrong. This can change the optimal value of the optimality criterion. In the complex systems of the mentioned processes, the separating node is one of the main conditions. A recirculation system usually consists of reactors, separators and other associated units. An inversely related process is carried out with a continuous output of reaction products between the steps and the input of the unreacted part of the previous raw material at each subsequent step. It seems clear that process optimization considering recirculation and kinetics simultaneously is usually not sufficient. To obtain realistic results, it is necessary to use the above equations together with the equations of the processes taking place in the separator.In this work, the results of the study of the preparation of the theoretical regularities of the adsorption-separation junctions of recirculated chemical-technological complexes and their practical use are shown. During the mathematical modeling, along with other nodes of the complex, the main attention was paid to the adsorption node and additions to German results in practice. Keywords: propane, cracking, n-pentane, isopentane, methane, hydrogen, hydrocarbon.

Müasir dövrdə malların yüksək keyfiyyətinin müəssisənin uğurunda həlledici amil olması getdikcə aydınlaşır. Bu prinsipə riayət etmək ölkənin qlobal rəqabət qabiliyyətinə nail olmaq və onun həyat keyfiyyətini təmin etmək üçün ən mühüm şərtlərdən biridir. Yerli maşınqayırma müəssisələrinin məhsullarının yüksək keyfiyyətinin təmin edilməsi probleminin həlli zərurəti elmi-texniki tərəqqinin əsas elementidir. Bundan əlavə, keyfiyyət məsələlərinin həlli satış bazarının davamlı olaraq genişlənməsinə və mənfəətin artmasına, eləcə də müştəri tələbinin ödənilməsinə kömək edir. Ona görə də bu gün bu məsələ xüsusi əhəmiyyət kəsb edir. İstehsalın bütün digər sahələrində və qeyri-istehsal fəaliyyət sahələrində mütərəqqi dəyişikliklər əsasən maşınqayırma sənayesinin məhsullarının keyfiyyətindən asılıdır. Məhsulun keyfiyyət səviyyəsi həm xarici, həm də yerli müəssisələr üçün ən mühüm prioritetlərdən biridir. Bu baxımdan məhsulun keyfiyyətinin qiymətləndirilməsi üsullarının, onların formalaşma xüsusiyyətlərinin, idarə edilməsinin, səviyyəsinin təhlili üsullarının, habelə təşkilatlar üçün əhəmiyyətinin öyrənilməsi həm nəzəri, həm də praktiki baxımdan aktualdır. Həmçinin məhsulun keyfiyyətinin formalaşması prosesləri müəyyən qanunlara tabedir. Beləliklə, maşınqayırma müəssisələri tərəfindən məhsulun keyfiyyəti problemlərinin getdikcə artan aktuallığı, onların səviyyəsinin təmin edilməsinin nəzəri və praktiki əsaslarının öyrənilməsi bu işin mövzusunun, məqsədlərinin, vəzifələrinin, əsaslandırılmasının və strukturunun seçilməsini müəyyən edir. Açar sözlər: maşınqayırma, idarəetmə, məhsulun keyfiyyəti, nəzarət, istehsal

The paper develops a hybrid algorithm for predicting a linear dynamic system based on a combination of an adaptive Kalman filter with preprocessing using a wavelet packet analysis of the initial data of the background of the system under study. Being based on Fourier analysis, wavelet analysis and wavelet packet analysis are quite acceptable for time-frequency analysis of a signal, but they cannot be performed recursively and in real time and, therefore, cannot be used for dynamic analysis of random processes. In combination with the Kalman filter, a combination of the characteristics of the multiple-resolution wavelet transform and the recurrent formulas of the Kalman filter in real time is obtained. Since the original signal is usually given in the form of discrete measurements, to implement their convolution used in the Kalman filter, it is necessary to use cyclic convolutions with periodic continuation of the signal for any time interval. In the case of different values of the original signal at the ends of the considered time interval [0,T], the periodized signal can have large values and sharp different amplitude at the ends of the periodization interval. To smooth out the values of the periodized signal at the ends of the periodization interval, a cascade decomposition and recovery algorithm was used using Dobshy boundary wavelets with a finite number of moments. Signal recovery is performed in a series of operations comparable to the duration of the time interval under consideration. The smoothed signal obtained in this way is used as a Kalman filter platform for predicting the dynamic system under study. Taking into account that the correlation functions of the noise in the observation equation and the phase state of the system are usually unknown, the adaptation of the Kalman filter to these noises (interference) is carried out on the basis of a zeroing sequence. The manuscript does not contain related data

More than half of those who succumb to cancer each year also lose their battle with the disease, making cancer a leading cause of death worldwide. After surgery, hormonal therapy, radiotherapy and chemotherapy, which are preferred in cancer management, immunotherapy has revolutionized. In this mini-review, we cover the various immunotherapeutic approaches used in contemporary cancer immunotherapies. These are immune checkpoint blockade, an attemp planned to ‘unleash’ robust T cell responses, and adaptive cellular therapies connected on the infusion of tumor-struggling immune cells into the body. One of these attemps, Nivolumab, became the first ICI to be approved to treat lung cancer in 2014. To date, different ICIs, such as pembrolizumab, atezolizumab, and durvalumab, have been in a row introduced into clinical medicine and have shown significant effect. Therefore, in this mini-review, we present some emerging goals and attemps in cancer immunotherapy.

There are primarily two relations currently being used in the literature to calculate the metal abundance of ab-type RR Lyrae variables from their periods andV-band amplitudes. They are the one from Alcock et al., which utilizes both the stars’ period and amplitude and the one from Sarajedini et al., which makes use of solely the stars’ period of modulation. In this work, we are seeking to test which of these relations is most accurate in reproducing the spectroscopic metal abundances of Galactic globular clusters containing ab-type RR Lyraes to which we can apply these relations. For our sample of 600 ab-type RR Lyrae variables in 33 Galactic globular clusters, we find very similar results for both equations as regards the accuracy of the mean metallicity calculated for each globular cluster as compared with spectroscopic abundance measurements for these clusters. This implies that knowledge of only the periods of ab-type RR Lyrae variables in a globular cluster is sufficient to allow a determination of the mean metallicity of that cluster. In particular, once corrected for the adopted metallicity scale, both of these equations are able to reproduce the spectroscopic metal abundance of each cluster with an accuracy of ±0.28 dex.

Geoloji modelləşdirmə əsasən geoloji cismin həndəsi modelinin səpələnmiş geoloji məlumatlar əsasında necə çıxarıldığını öyrənir. Nümunələrdən götürülmüş geoloji məlumatlar 3 əsas xarakteristikaya malikdir: çox mənbəli, səpələnmiş və qeyri-bərabər. Naməlum bölgələrdə bir modelin paylanma trendini çıxarmaq və proqnozlaşdırmaq üçün məhdud sayda nümunələrin məlumatlarından istifadə etmək böyük bir problemdir və müvafiq modelləşdirmə nəticələri də daha çox qeyri-müəyyənliyə malikdir. Etibarlı üçölçülü geoloji modelin (xüsusilə süxur hissəcikləri modeli) yaradılması mineral ehtiyatların, palçıq vulkan və rezervlərin hesablanması və mədən işlərinin layihələndirilməsi üçün mühüm əhəmiyyət kəsb edir. Açar sözlər: geoloji modelləşdirmə; normal qiymətləndirmə; qeyri-müəyyən modelləşdirmə; nöqtə buludu; palçıq vulkanı

Elektrik şəbəkəsinin keyfiyyət göstəriciləri araşdırılmış və onların parametrlərinin müasir nəzarət ölçü chazlarının işinə təsiri təhlil edilmişdir. Elektrik enerjisinin keyfiyyət göstəricilərinə nəzarət edən ölçü sistemlərinin arxitekturası müəyyən edilmişdir. Elektrik cihazlarının etibarlı işinin təmin edilməsi üçün tətbiq olunan nəzarət ölçü sistemləri və onları qidalandıran elektrik şəbəkələrinin keyfiyyət göstəricilərinə ən çox gərginlik və tezlik parametrlərinin kənaraçıxmasının təsir etdiyi müəyyən edilmişdir. Açar sözlər: elektrik enerjisi, keyfiyyət göstəriciləri, nəzarət ölçü sistemləri, elektrik şəbəkələri, düzləndirici.

Geotermal suların kompleks istifadəsi imkanları araşdırılmış, prosesin idarə edilmə məsələsi tədqiq edilmiş, müsbət nəticələr əldə olunmuşdur. Termal suların tərkib və xüsusiyyətlərindən asılı olaraq geotermal ehtiyatların istifadəsinin əsas istiqaməti təyin edilmişdir. Termal sulardan kompleks istifadənin təmin edilməsi məqsədilə bu suların axıdıldığı boruların korroziyaya davamlılıq məsələsinə baxılmışdır. Açar sözlər: geotermal enerji, buxar turbini, generator, alternativ mənbələr, elektrik enerjisi.

This randomized controlled trial study aims to examine the flipped classroom model's effects on the knowledge and health beliefs of testicular cancer and testicular self-examination. The study was conducted on 66 students in Northern Cyprus. A descriptive information form, Champion’s Health Belief Model Scale, visual analogue scale of satisfaction with the learning method, the knowledge questionnaire on testicular cancer and the testicular self-examination itself were used for data collection. The mean posttest knowledge score of the intervention group (14.44) was higher than the mean posttest knowledge score of the control group (12.65). The difference between groups was statistically significant (P

This study carried out an experimental and numerical modal analysis of the Turkish traditional instrument 'Bendir' by an acoustical excitation source. In experimental modal analysis, Bendir was excited acoustically for specified frequencies and elastic deformations of different areas of Bendir due to the excitation were observed with a laser vibrometer. Using the Fourier series handled gained data, modal analysis was done. The first six natural frequencies obtained experimentally and numerically were compared. In addition, other hits in Bendir, symbolizing three fundamental voices such as 'dum', 'te', 'ke' were used to excite the instrument. As a result, time dependent deformation & velocity data were determined and different responses of Bendir were compared.

Objective: The role of health professionals working in primary care in providing services to all segments of society and in protecting and improving the health of all individuals is extremely important. The aim of this study is to determine the healthy lifestyle behaviors of primary health care workers in Karabük city center and to examine some factors that may affect the choice of a healthy lifestyle. Materials and Methods: This cross-sectional study was conducted between October-December 2019 with the participation of 334 healthcare professionals in Karabük. The questionnaire with 27 questions and the Healthy Lifestyle Behaviors Scale II (HLBS-II) were administered. Results: The median age of the health care workers participating in the study was 38.2 ± 10.6. Of the participants 53.8% were women and approximately three-quarters of the participants (70.8%) were married. In terms of occupational groups, 10.9% of the participants were physicians, 25.0% were nurses and midwives, 16.7% were health officers/technicians and 47.4% were composed of other employees. The HLBS-II total score was found to be 126.8±21.3. The HLBS-II total score were higher in women, those who defined their health status as good, university graduates those who did not smoke, had good nutrition, exercised, and were satisfied with their body appearance. Conclusion: In our study, it was found that the healthy life behavior scores of health workers were at a good level. Especially men, smokers, high school graduates, obese, those who do not pay attention to their nutrition and physical activity should be informed and be supported by healthy living behavior programs.

Purpose: The aim of this study was to develop radiomics signature-based magnetic resonance imaging (MRI) to determine adrenal Cushing’s syndrome (ACS) in adrenal incidentalomas (AI). Material and methods: A total of 50 patients with AI were included in this study. The patients were grouped as nonfunctional adrenal incidentaloma (NFAI) and ACS. The lesions were segmented on unenhanced T1-weighted (T1W) in-phase (IP) and opposed-phase (OP) as well as on T2-weighted (T2-W) 3-Tesla MRIs. The LASSO regression model was used for the selection of potential predictors from 111 texture features for each sequence. The radiomics scores were compared between the groups. Results: The median radiomics score in T1W-Op for the NFAI and ACS were -1.17 and -0.17, respectively (p < 0.001). Patients with ACS had significantly higher radiomics scores than NFAI patients in all phases (p < 0.001 for all). The AUCs for radiomics scores in T1W-Op, T1W-Ip, and T2W were 0.862 (95% CI: 0.742-0.983), 0.892 (95% CI: 0.774-0.999), and 0.994 (95% CI: 0.982-0.999), respectively. Conclusion: The developed MRI-based radiomic scores can yield high AUCs for prediction of ACS.

Depuis quelques années, l’immigration des personnes de différentes langues et de cultures ne cesse de croître dans le monde entier. Ce phénomène aboutit à un échange et un partage des langues et des cultures. Ces échanges sont d’une part une richesse culturelle pour la société d’accueil et, d’autre part ils peuvent aussi affecter négativement le maintien de la langue d’origine pour les immigrés. Ce maintien est important parce qu’au-delà d’une richesse culturelle, c’est aussi la marque de l’identité et de l’estime de soi pour l’individu. La France est depuis longtemps une terre d’accueil pour des immigrés originaires de divers pays dont l’une est la Turquie. Que ce soit pour des raisons politiques ou économiques, la population turque fait partie des premiers immigrés en France. Dans cet article, nous allons étudier le cas des jeunes de la troisième génération issus de familles immigrées originaires de la Turquie. L’objectif principal est de comprendre leurs représentations et pratiques de la langue d’origine et celle de la société environnante. Pour ce faire, nous nous sommes basés sur une étude qualitative et nous avons interrogés 30 turcophones dont l’âge varie entre 18 et 30. Les données obtenues ont été soumises à une analyse descriptive et une analyse de contenu. Les jeunes de la troisième génération deviennent bilingues dès leurs plus jeunes âges, et la majorité de leur temps passe en milieux francophones. Les résultats de la recherche montrent que les jeunes interrogés ont une représentation positive quant au maintien de la langue et de la culture d’origine. Leur pratique du turc et du français dépend des interlocuteurs et des situations. Le turc, la langue d’origine occupant une place importante dans leur vie quotidienne, ils espèrent la préserver et la transmettre mais la réalité est qu’elle est moins pratiquée qu’auparavant et peut l’être encore moins dans l’avenir.

İç Kalite Kontrol (İKK), hasta numunelerini çalıştırmadan önce bir laboratuvar testinin güvenilirliğini değerlendirme ve kontrol etme sürecidir. Mevcut İKK süreci, kural tabanlı yaklaşımlar kullanarak Toplam Analitik Hatanın (TAE) yönetimine odaklanmaktadır. Toplam İzin Verilebilir Hata (TEa) ihlallerinin zamanlamasını tam olarak tahmin edemez. Çalışmada, Tahmine Dayalı Kalite Kontrol Algoritması (PQCA) için Gaussian Process for Machine Learning (GPML) yöntemini kullanarak İKK sürecini değerlendirmede tahmine dayalı bir hesaplama yaklaşımı önerildi. Python ve Scikit-learn kütüphanesinde yürütülen yazılım uygulaması, Windows tabanlı standart bir PC üzerinde çalıştırıldı. PQCA'ya dayalı bir dijital kontrol tablosu oluşturuldu. Gözlemlerin, PQCA tarafından üretilen karşılık gelen tahminlerinin %95 güven aralığı içinde kaldığı gösterildi. Ayrıca, klasik formül kullanılarak hesaplanan TAE'nin tüm TEa ihlallerini yakalayamadığı da ortaya konuldu. PQCA, ham kontrol verilerini doğrudan kalite hedefleriyle ilişkilendirebilen basit bir prosedür olup, yüksek derecede doğrulukla tahmine dayalı bir yaklaşım sağlamıştır. Klasik TAE hesaplama modeli, tek değişkenli bir Gauss modeline dayanır. PQCA'nın temel aldığı GPML, çok değişkenli bir Gaussian modeldir. Bu nedenle PQCA, klasik IQC modelinin bir genellemesi olarak görülebilir. Laboratuvarlar, PQCA'yı kullanarak analitik kalitenin kontrolüne proaktif bir yaklaşım getirebilir, düzenleyici kurumların gereksinimlerini karşılayabilir ve dolayısıyla daha doğru ve güvenilir hasta sonuçları sağlayabilir. PQCA tabanlı İKK, geleneksel yöntemlerin eksikliklerinin üstesinden gelen tek bir algoritma kullanarak analitik değişkenliğin kontrolünü sağlayabilir. Gelecekte, yeni kullanılabilir hesaplama modelleri, İKK için daha karmaşık, tahmine dayalı matematiksel çerçeveleri mümkün kılacaktır.

Der Dichter und Schriftsteller Boris Pasternak hatte seit seiner Jugend eine besonders enge Bindung zu Deutschland und zur deutschen Kultur entwickelt.In seinen beiden längeren Aufenthalten in Deutschland, im Jahr 1905 und im Jahr 1912, eignete sich Pasternak die deutsche Sprache an, machte sich mit der deutschen Literatur vertraut, speziell der Romantik, widmete sich zuerst der Musik, dann dem Studium der Philosophie, insbesondere dem Marburger Neukantianer Hermann Cohen. Die Philosophie betrachtete Pasternak als wichtige Quelle für seine Poesie.Von 1946 bis 1955 arbeitete Boris Pasternak indes an seinem ersten und einzigen Roman „Doktor Schiwago“. Der Roman durfte nicht gedruckt werden, weil er in der Sowjetunion als regimekritisch verdächtigt wurde. Da durfte der Roman offiziell auch erst 1988 erscheinen. Außerhalb Russlands wurde der Roman jedoch auf Anhieb ein internationaler Erfolg, da „Doktor Schiwago“ in rascher Folge in 18 Sprachen übersetzt wurde.In Deutschland begann die Erfolgsgeschichte bereits 1958, nachdem die erste deutsche Übersetzung von Reinhold von Walter im S. Fischer Verlag Frankfurt am Main erschienen war.Der Beitrag diskutiert, wie Pasternak und sein Roman „Doktor Schiwago“ in Deutschland rezipiert wurde und wie gerade dieser Roman eine „transkulturelle“ Rezeptionswirkung im Deutschland des 20. Jahrhunderts entfaltet hatte.

In this study, an in vitro propagation protocol of Poncirus trifoliata L. (Raf.) rootstock, which is one of the main rootstocks used in citrus, was created. Monocular node parts of the plant, which is the source of explant, were cultured in MS nutrient media containing BAP at dissmilar concentrations (0.5-1.0-2.0 mg/l). Afterward, it was observed that shoot appearance and tillering were achieved in the node explants cultured in MS nutrient medium comprising 1.0 mg/l BAP. The shoots were removed to a new culture in MS nutrient media containing NAA and IBA for rooting. While 30% rooting was achieved in the rooting medium, 62% of the rooted plantlets were acclimated to external conditions. 2 mg/l BAP and 2 mg/l silver nitrate (AgNO3) doses were supplied to the MS medium. The results of this study were obtained and a compound was found to the yellowing and leaf fall problem. As a result, in vitro propagation of Poncirus trifoliata, which is among the important citrus rootstocks, was tried, and its rooting ability was investigated in different nutrient media concentrations after shoots were obtained from different explants.

Objectives Use of complementary and alternative medicine (CAM) is widespread. This study aimed to investigate the use of CAM in children with central precocious puberty (PP) who used gonadotropin-releasing hormone analog (GnRHa) treatment. Methods Parents of 108 patients who were diagnosed as having PP were involved in the study. A questionnaire was administered to the parents during follow-ups. The patients were divided into two groups according to the use of CAM. Results Forty (37%) patients had used CAM. Parents who graduated from primary school tended not to use CAM (χ 2 =10.463; p=0.015). There was no other statistically significant difference between the sociodemographic features (p>0.05). The most common information source was physicians (40%). Seventy-five percentage of CAM users and 44.1% of non-CAM users knew/heard about herbal medicine (χ 2 =8.517; p=0.004) and herbal medicine was the most common type of CAM used. 80% of parents in the CAM group and 54.4% of parents in the non-CAM group knew at least one biologically based therapy that had estrogenic activity (χ 2 =6.082; p=0.014). Seventy-one percentage of parents in the CAM group and 29% of parents in the non-CAM group stated that they would consider using CAM in the future (χ 2 =16.979; p Conclusions The use of CAM among patients with PP is high. Although most CAM therapies are harmless, there may be adverse effects or drug interactions with current conventional treatment in children. Health professionals should be aware and inquire about the use and type of CAM, considering the medical history at every patient encounter.

Devletin ekonomideki hacmi gerek iktisadi yaklaşımlardan gerekse devletin üstlendiği fonksiyonlardan zaman içinde etkilenmiştir. Devletin ekonomiye müdahalesi bir yandan piyasa başarısızlıklarını ortadan kaldırma amacına hizmet ederken, diğer yandan devletin başarısızlıklarının artmasının da nedeni olmuştur. Devletin başarısızlıkları arasında yer alan hizmet kayırmacılığı, politikacıların kamu kaynaklarını tekrar seçilme amacıyla dağıtmaları sonucunda, ekonomik etkinsizliklere yol açan bir siyasal yozlaşma türüdür. Ülkelerde uygulanan seçim sistemi, bütçe süreci, komisyonların varlığı, siyasi rejim, ideolojik ve partizan tutumlar gibi faktörler hizmet kayırmacılığını etkilemektedir. Türkiye’de ise hizmet kayırmacılığı genellikle parti politikaları çerçevesinde gerçekleşmektedir.

Objective We aimed to evaluate intracytoplasmic sperm injection (ICSI) outcomes in young patients with diminished ovarian reserve (DOR) plus severe male factor (SMF) compared with age-matched controls with DOR. Study design A total of 189 infertile women under 35 years with DOR undergoing ICSI procedures were included retrospectively. Participants whose partners' sperm analysis was normal considered as the DOR group (n = 154) and whose partners' had SMF considered as the DOR + SMF group (n = 35). The two groups were compared regarding cycle characteristics and pregnancy outcomes. Results Demographic features except infertility duration were similar between two groups. The duration of infertility was significantly longer in the DOR + SMF group compared to the DOR group (p = 0.02). Ovarian stimulation characteristics, oocyte retrieval parameters, fertilization rate, quality of embryos, embryo cancellation rate, and development up to blastocyst stage were found similar between two groups. Implantation, clinical pregnancy, abortion, and live birth rate, multiple pregnancy rate per cycle were distributed homogenously between the DOR and DOR + SMF groups. Regarding perinatal and neonatal outcomes of groups, fetal height and weight were significantly lower in DOR + SMF group than in DOR group (p = 0.001 and 0.01, respectively). Gestational week at delivery was lower in the DOR + SMF group compared to the DOR group (p < 0.0001). Conclusion Fetal anthropometric measures were lower regarding to preterm delivery in the DOR + SMF group than the DOR group. Large sample-sized studies should be performed to explain the decreased gestational week at the time of delivery in the DOR + SMF group.

We aimed to evaluate the interchangeability of sodium, potassium, hemoglobin, and hematocrit measurement between the blood gas analyzers and laboratory automatic analyzers results.This was a retrospective cross-sectional study. The results of 1927 paired samples analyzed simultaneously with the blood gas analyzer and the laboratory automatic analyzer were compared. The Bland-Altman and Cohen's kappa statistic detected the agreement between the two analyses.The limits of agreement (±1.96 standard deviation of the mean difference) were -11.1 to 20.3 for sodium, -1.9 to 0.5 for potassium, -16.1 to 12.9 for hematocrit, and -5.0 to 4.0 for hemoglobin. Agreement between the two analyses was not acceptable within the defined clinically acceptable limits. In addition, none of the kappa values were higher than 0.60, which highlights the lack of agreement between the two analyzers.The blood gas analyzers and laboratory automatic analyzers results cannot be used interchangeably.

At European scale, soil characteristics are needed to evaluate soil quality, soil health and soi l-based ecosystem services in the context of the European Green Deal. While some soil databases exist at the European scale, a much larger wealth of data is present in individual European countries, al l owing a more detailed soil assessment. There is thus an urgent and crucial need to combine these data at t h e European scale. In the frame of a large European Joint Programme on agricultural soils launched by the European Commission, a survey was conducted in the spring of 2020, i n the 24 European participating countries to assess the existing soil data sources, focusing on agricultural soils. The survey will become a contribution to the European Soil Observatory, launched in December 2020, which aims to collect metadata of soil databases related to all kind of land uses, including fores t and urban soils. Based upon a comprehensive questionnaire, 170 soil databases were identified at local, regional and national scales. Soil parameters were divided into f i ve groups: 1. main soil parametersaccording to the Global Soil Map specifications; 2. other soil chemical parameters; 3. oth e r physical parameters; 4. other pedological parameters; and 5. soil biological features. A classification based onthe environmental zones of Europe was used to distinguish the climatic zones. This survey shows that while most of the main pedological and chemical parameters are included in more than 70 % of the country soil databases, water content, contamination with organic pollutants and biological parameters are the least frequently reported parameters. Such differences will have conse que nce s when developing an EU policy on soil health as proposed under the EU soil strategy for 2023 and using the data to derive soil health indicators. Many differences in the me thods used in collecting, preparing, and analysing the soils were found, thus requiring harmonisation procedures and more cooperation among countries and with the EU to use the data at the European scale Additionally, choosing harmonized and useful interpretation and threshold values f or EU soil indicators may be challenging due to the different methods used and the wide variety of soil land-use and climate combinations influencing possible thresholds. The temporal scale of the soil databases reported is also extremely wide, starting from the ‘20s of the 20th century.

Background: Idiopathic pulmonary fibrosis (IPF) predominantly affects people over the age of 60 years and its incidence increases with age. Limited data is available on the use of antifibrotics in the elderly IPF population. We aimed to examine the tolerability and safety of antifibrotics (pirfenidone, nintedanib) in elderly patients with IPF in a real-world setting. Methods: Medical records of 284 elderly (≥75 years) and 446 non-elderly IPF patients (

There are often bonding problems between acrylic resins and silicone. PEEK (polyetheretherketone), which is a high-performance polymer, has great potential for the implant, and fixed or removable prosthodontics. The aim of this study was to evaluate the effect of different surface treatments on PEEK to be bonded to maxillofacial silicone elastomers. A total of 48 specimens were fabricated from either PEEK or PMMA (Polymethylmethacrylate) (n = 8). PMMA specimens acted as a positive control group. PEEK specimens were divided into five study groups as surface treatments as control PEEK, silica-coating, plasma etching, grinding, or nano-second fiber laser. Surface topographies were evaluated by scanning electron microscopy (SEM). A platinum-primer was used on top of all specimens including control groups prior to silicone polymerization. The peel bond strength of the specimens to a platinum-type silicone elastomer was tested at a cross-head speed of 5 mm/min. The data were statistically analyzed (α = 0.05). The control PEEK group showed the highest bond strength (p < 0.05) among the groups. No statistical difference was found between control PEEK, grinding, or plasma etching groups (p > 0.05). The lowest bond strength was seen in the laser group, which was not statistically different from silica-coating (p > 0.05), and statistically different from control PEEK, grinding, or plasma groups (p < 0.05). Positive control PMMA specimens had statistically lower bond strength than either control PEEK or plasma etching groups (p < 0.05). All specimens exhibited adhesive failure after a peel test. The study results indicate that PEEK could serve as a potential alternative substructure for implant-retained silicone prostheses.

In many cases, the formation of the country and the state is connected with the name of geniuses raised by the people. The formation of modern Azerbaijan, the establishment and development of an independent republic coincided with the years 1969-1982 and 1993-2003, when the great leader Heydar Aliyev led the state. At a time when economic development is observed in our country, the role of Heydar Aliyev in the rapid rise in the field of architecture and construction is irreplaceable. Heydar Aliyev, an art-loving personality who wanted to become an architect as his first dream, later, he became a political architect as the head of Azerbaijan and was able to create a very valuable legacy. From time to time, this heritage will be the focus of scientific-practical research, professional views, and will be studied.

Despite numerous studies in the field of creating rubber products, to date, the choice of material for the manufacture of packer sealing elements has not found its solution. This issue becomes especially important drilling deep and ultra deep wells. The article is devoted to the choice of a composite material based on a polymer with highly elastic fillers. Keywords: Polymer matrix, nanoparticles, composite material, sealing element, packer.

Background: Polyomavirus BK virus infection is a significant complication of renal transplantation and is an important cause of allograft loss. Today, despite the innovations in the pharmaceutical industry, a curative treatment against the BK virus has not been developed. The management is not standardized and is generally based on reported experience from transplantation centers. However, the literature on the subject with large samples is limited. Therefore, we designed a study to present our countrywide experience with BK virus nephropathy (BKVN) in renal transplant recipients. Methods: Our study was conducted with thirty kidney transplant centers from all provinces of Turkey. Only cases with BKVN proven by allograft biopsy were included in our study. Demographic characteristics and laboratory values of the patients were obtained from the archives and electronic databases of the centers. Results: A total of 13.857 patients from 30 transplantation centers were screened. 207 BKVN cases proven by allograft biopsy were identified and included in the study. The mean age was 46.4±13.1, and 146 (70.5%) patients were male. Twenty-six patients did not receive any induction therapy, 144 patients received anti-T lymphocyte globulin (ATLG), and 37 patients received basiliximab after transplantation. 23.6% of the patients had acute rejection history in the first six months of renal transplantation. all were treated with pulse steroids, and 46 were also treated with ATLG. The mean time to diagnosis of BKVN was 15.8±22.2 months after transplantation. At the time of diagnosis, the patients’ mean creatinine level was 1.8±0.7 mg/dl, and the mean estimated glomerular filtration rate was 45.8±19.6 ml/min. While BKVN was solely reported in 181 cases, there were cellular rejection findings in 21 biopsy specimens and humoral rejection in 4 biopsy specimens. In addition of dose reduction or discontinuation of immunosuppressive drugs, eighteen patients were treated with cidofovir, 11 patients with leflunomide, 17 patients with quinolones, 15 patients with intravenous immunoglobulin (IVIG), five patients with cidofovir+IVIG, and 12 patients with leflunomide+IVIG. None of the patients who received leflunomide and leflunomide+IVIG had allograft loss. Allograft loss was observed in 12 (15%) of 78 patients treated with antivirals or immunomodulators. Allograft loss occurred in 32 patients (15%) during follow-up out of 207 patients with BKVN. Five patients were retransplanted, and none developed BKVN during the follow-up. Conclusions: BKVN is still a significant cause of allograft loss in kidney transplantation, which has not been fully elucidated. Leflunomide appears to be an effective treatment in these patients.

The object of research is the problem of torsion for a radially inhomogeneous transversally isotropic sphere and the study based on this three-dimensional stress-strain state. To establish the scope of applicability of existing applied theories and to create more refined applied theories of inhomogeneous shells, it is important to study the stress-strain state of inhomogeneous bodies based on three-dimensional equations of elasticity theory. The problem of torsion of a radially inhomogeneous transversally isotropic non-closed sphere containing none of the poles 0 and π is considered. It is believed that the elastic moduli are linear functions of the radius of the sphere. It is assumed that the lateral surface of the sphere is free from stresses, and arbitrary stresses are given on the conic sections, leaving the sphere in equilibrium. The formulated boundary value problem is reduced to a spectral problem. After fulfilling the homogeneous boundary conditions specified on the side surfaces of the sphere, a characteristic equation is obtained with respect to the spectral parameter. The corresponding solutions are constructed depending on the roots of the characteristic equation. It is shown that the solution corresponding to the first group of roots is penetrating, and the stress state determined by this solution is equivalent to the torques of the stresses acting in an arbitrary section θ=const. The solutions corresponding to the countable set of the second group of roots have the character of a boundary layer localized in conic slices. In the case of significant anisotropy, some boundary layer solutions decay weakly and can cover the entire region occupied by the sphere. On the basis of the performed three-dimensional analysis, new classes of solutions (solutions having the character of a boundary layer) are obtained, which are absent in applied theories. In contrast to an isotropic radially inhomogeneous sphere, for a transversely isotropic radially inhomogeneous sphere, a weakly damped boundary layer solution appears, which can penetrate deep far from the conical sections and change the picture of the stress-strain state., Об'єктом дослідження є завдання кручення для радіально-неоднорідної трансверсально-ізотропної сфери та дослідження на базі цього тривимірного напружено-деформованого стану. Для встановлення області застосування існуючих прикладних теорій та з метою створення більш уточнених прикладних теорій неоднорідних оболонок актуальним є вивчення напружено-деформованого стану неоднорідних тіл на основі тривимірних рівнянь теорії пружності. Розглянуто завдання кручення радіально-неоднорідної трансверсально-ізотропної незамкнутої сфери, що не містить жодного з полюсів 0 і π. Вважається, що модулі пружності є лінійними функціями від радіусу сфери. Передбачається, що бічна поверхня сфери вільна від напруги, а на конічних перерізах задані довільні напруги, що залишають сферу в рівновазі. Сформульована крайова задача приведена до спектрального завдання. Після виконання однорідних граничних умов, заданих на бічних поверхнях сфери, одержано характеристичне рівняння щодо спектрального параметра. Побудовано відповідні рішення, що залежать від коріння характеристичного рівняння. Показано, що рішення, що відповідає першій групі коренів, є проникним, і напружений стан, що визначається цим рішенням, еквівалентно крутним моментам напруг, що діють у довільному перерізі θ=const. Рішення, відповідні зліченній множині другої групи коренів, мають характер прикордонного шару, локалізованого в конічних зрізах. У разі суттєвої анізотропії деякі прикордонні рішення слабо загасають і можуть охоплювати всю область, зайняту сферою. На основі проведеного тривимірного аналізу отримано нові класи рішень (рішень, що мають характер прикордонного шару), які відсутні у прикладних теоріях. На відміну від ізотропної радіально-неоднорідної сфери, для трансверсально-ізотропної радіально-неоднорідної сфери з'являється слабко загасаюче прикордонне рішення, яке може проникати глибоко далеко від конічних перерізів і змінювати картину напружено-деформованого стану.

To test the hypothesis that routine dental radiographs can be used to draw conclusions regarding the mandibular canal (MC) localization. MATERIAL AND METHODS: A total of 108 radiographs (36 orthopantomograms [OPTs], 36 lateral cephalograms [LCs], and 36 cone-beam computed tomograms [CBCTs]) of 36 patients were analyzed. Statistical analysis included all cephalometric parameters obtained by OPTs, LCs, and CBCTs. Potential influencing parameters were calculated using linear and logistic regression with a backward removal algorithm. For predictability of MC localization, parameters were correlated using Pearson's correlation.The MC ran along the lingual half (n = 24) twice as often as in the buccal half (n = 12) in the population studied. The position was always symmetrical contralaterally. No sex-specific influence was observed (p = .34). Lingual and buccal MC courses were statistically significantly correlated to increased and decreased jaw angles (LC/OPT), respectively (p = .003; r = -.48/p = .010; r = -.42). An increased jaw angle was significantly correlated with a more cranial MC position (p = .013; r = -.41); a deep and distal bite position was significantly correlated with a caudal and buccal MC position (p = .004; r = -.47/p = .001; r = .57). Moreover, an increase of 1 point in the Hasund score predicted an increased probability of a buccal MC position by 18.6%. The jaw angle analyzed in OPT and LC images were positively correlated (r = .89, p .001).Routine dental radiographs provide informative guidance on the location of the MC in the vertical and transverse levels. This finding could be used in the initial consultation and treatment planning to consider more invasive diagnostic methods further down the line.

To evaluate several lymphocyte subtypes with various parameters that can be applied easily and give fast results for their roles in evaluating the stage and prognosis of acute biliary pancreatitis.Case-control study.The Emergency Department of Istanbul Training and Research Hospital, and Gaziosmanpasa Research and Training Hospital, Turkey, between June 2020 and April 2021.Patients, who admitted to the Emergency Department with acute pancreatitis and treated after hospitalisation, were included in the study. The patients were divided into three groups; mild, moderately severe and severe, according to the 2012 revised Atlanta classification. Hematocrit, creatinine, potassium, sodium values, and flow cytometry ratios of lymphocyte, monocyte, CD4+, CD8+, and regulatory T cells were measured and the difference between the groups were evaluated. Their results were compared with healthy volunteers.A total of 53 persons including 40 with acute pancreatitis (14 mild, 14 moderately severe, and 12 in the severe pancreatitis groups) and 13 healthy volunteers, were included in the study. The average age of the studied participants was 50.9 ±13.42 years, 43.3% males and 56.7% females. Leukocyte values, lymphocyte rates, hematocrit rates, age, hospital staying duration, creatinine, potassium values, CD4+, and CD3+ lymphocyte rates were found to be different at a statistically significant level between the groups.High leukocyte, low lymphocyte, high hematocrit, advanced age, elevated creatinine, elevated potassium, low CD4+ T lymphocyte, low CD3+ T lymphocyte, and low lymphocyte/monocyte ratio were identified as poor prognostic indicators.Acute pancreatitis, Flow cytometry, Regulatory T cell, Atlanta.

It is generally accepted, that drinking tea and coffee causes an increase in cortisol levels in majority of people, due to the presence of alkaloids in these drinks, main of which is caffeine. The literature data about the ability of alkaloids to increase the cortisol secretion, and the high consumption of these beverages by men in our population, as well as the relatively scarce information on their effects on the body, forced us to focus in this study on examination the role of tea and coffee on the change in cortisol and testosterone levels in young men after taking strong tea or coffee at rest. İn this study we examined influence of coffee and tea on 21 healthy young men on testosterone and cortisol levels in the blood. For this, Hema kit (Russia) enzyme immunoassay method was used for testosterone definition, and Steroid ELISA-cortisol kit (Russia) – for serum cortisol levels in blood serum. We found out that cortisol may be lowered or raised depending on individuals, while testosterone does not change significantly either under action of coffee or tea.

Background: Heart failure (HF) due to myocarditis might not respond in the same way to standard therapy as HF due to other aetiologies. The aim of this study was to investigate the value of endomyocardial biopsies (EMB) for clinical decision-making and its relation to the outcome of paediatric patients with myocarditis. Methods: Clinical and EMB data of children with myocarditis collected for the MYKKE-registry between 2013 and 2020 from 23 centres were analysed. EMB studies included histology, immunohistology, and molecular pathology. The occurrence of major adverse cardiac events (MACE) including mechanical circulatory support (MCS), heart transplantation, and/or death was defined as a combined endpoint. Results: Myocarditis was diagnosed in 209/260 patients: 64% healing/chronic lymphocytic myocarditis, 23% acute lymphocytic myocarditis (AM), 14% healed myocarditis, no giant cell myocarditis. The median age was 12.8 (1.4-15.9) years. Time from symptom-onset to EMB was 11.0 (4.0-29.0) days. Children with AM and high amounts of mononuclear cell infiltrates were significantly younger with signs of HF compared to those with healing/chronic or healed myocarditis. Myocardial viral DNA/RNA detection had no significant effect on outcome. The worst event-free survival was seen in patients with healing/chronic myocarditis (24%), followed by acute (31%) and healed myocarditis (58%, p=0.294). A weaning rate of 64% from MCS was found in AM. Conclusions: EMB provides important information on the type and stage of myocardial inflammation and supports further decision-making. Children with fulminant clinical presentation, high amounts of mononuclear cell infiltrates or healing/chronic inflammation and young age have the highest risk for MACE.

It is known that the service life of oilfield machines and mechanisms is to a certain extent determined by the operability of friction units, the operation of which, as a rule, occurs under severe conditions (heavy loads, abrasive aqueous medium, etc.). It is also known that the determining parameters in the units of machines and mechanisms (lubricated with water) with polymer elements are specific load, sliding speed and relative clearance. In the field, these factors affect the coefficient of friction together, therefore, the study of their influence [µ = f (p, ʋ, ψ)] on the coefficient of friction is possible only with the use of mathematical modeling. We have studied the nature of the joint influence of the main operating parameters on the performance of the ison thermoplastic elastomer plain bearings. Keywords: Operation, polymer elements, field conditions, bearings, sliding speed.

The article discusses the stress state of the casing at the site of anchoring with anchor devices, the solutions of the problem are used. In the column, in interaction with the teeth of the anchor device rams, tangential and radial stresses are determined. Keywords: design and technological parameters, equipment, analytical calculations, anchor device, design scheme.

Tornadoes are the most violent and destructive of all the severe weather phenomena that localized convective storms produce. There is a requirement in operational meteorology increasing nowadays that an indicator index which allows to reduce the uncertainty of severe convective storms and tornadoes in the scope of climate change adaptation strategies. The main intention is not to replace or substitute modeling approaches, or composite indexes, but to warn operationally to draw attention to the Eastern Mediterranean and in particular a few days in advance. The development of some indicators using atmospheric variables can undertake a crucial role by enabling such numerical models to be run only at certain time intervals, thus enduring lower computational costs. In this study, Eastern Mediterranean Oscillation Index () has been developed in order to be able to detect the presence of (Upper Level Low) and approach is employed for selected storm events in . has 7 different its variations (members) which these members have been developed to detect differences depending on the entry directions of cyclones and storms influencing from the west of the country. In line with the GDAS data analysis, values of height are derived for the requirement of in a limited area. A few of the results from the study are as in the following: 86% of the trained tornado events revealed that the index was in negative phase at the time a tornado was reported, regardless of whether the events featured a convective storm or a frontal movement. The hourly period until the local minimum is obtained can be described and characterized as the process by which the index value decreases continuously. The time required to reach the local minimum varies based on the tornado occurrence. Based on the storm scenario in the test cluster in 2022 and the train cluster, this is predicted to be roughly 33,2 hours on average. In western , there is a 79% chance of a tornado occurring between six and forty-two hours after the index reaches its local minimum. In particular, the projected chance for this period is 63% between 12 and 30 hours after the local minimum is obtained. Besides, the majority of the tornado incidents with values below -0.75 were evaluated. After an index value falls below that threshold, it is likely to forecast the risk period of a tornado in with a probability of 79% and the local minimum point must be identified.

Lower body implants are designed according to the boundary conditions of gait data and tested against. However, due to diversity in cultural backgrounds, religious rituals might cause different ranges of motion and different loading patterns. Especially in the Eastern part of the world, diverse Activities of Daily Living (ADL) consist of salat, yoga rituals, and different style sitting postures. A database covering these diverse activities of the Eastern world is non-existent. This study focuses on data collection protocol and the creation of an online database of previously excluded ADL activities, targeting 200 healthy subjects via Qualisys and IMU motion capture systems, and force plates, from West and Middle East Asian populations with a special focus on the lower body joints. The current version of the database covers 50 volunteers for 13 different activities. The tasks are defined and listed in a table to create a database to search based on age, gender, BMI, type of activity, and motion capture system. The collected data is to be used for designing implants to allow these sorts of activities to be performed.

We report the successful management of a paratesticular liposarcoma, which, to the best of our knowledge, is the largest known of its type. A 62-year-old male presented with a painless, gradually progressive left testicular “giant” mass measuring 60 × 40 cm, weighing 30 kg and growing over a period of three 3 years. Additionally, a 5 × 5 cm trophic ulcer could be seen at the bottom of the scrotum. The ultrasound of the left testis revealed the testis having been completely replaced with a cystic and solid tumour. Preoperative serum testicular tumour markers (STM) were within normal limits. The markers included Alpha Feto Protein, Beta Human Chorionic Gonadotropin and Lactose Dehydrogenase. A left sided high inguino-scrotal approach with a huge skin resection including the trophic ulcer with complete removal of the tumour and a primary complex closure of the wound was performed. The post-operative period was uneventful, and histopathology revealed a dedifferentiated liposarcoma. We believe social taboo and fear of disfigurement impart a sense of shame in patients which led to the delayed presentation in a hospital in the index patient. The absence of metastases even with a protracted course is surprising.

Introduction: The most prevalent method for evaluating lung expansion in high-frequency oscillatory ventilation (HFOV) is chest X-ray (CXR). The purpose of this study was to compare the accuracy of chest radiography with point-of-care ultrasound (POCUS) in determining lung expansion. Methods: This prospective study included newborns who required HFOV and were being monitored in the Neonatal Intensive Care Unit. A single neonatologist assessed lung expansion with a chest x-ray and POCUS, to measure the costal level of the right hemidiaphragm and compare the results. Results: A neonatologist took 55 measurements on 28 newborns with a gestational age of 32 (23.2-39.4) weeks who were followed on HFOV. The rib counts obtained from anterior chest ultrasonography and posterior CXR showed a statistically high concordance (pConclusions: Lung ultrasonography is a reliable method in the evaluation of lung expansion in patients followed on HFOV.