85 results on '"Shui, Miao"'
Search Results
2. Study on Memristor-Based 3-D Convolutional Neural Network Adapting to Non-Ideal Effects
- Author
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Boyi Dong, Peixuan Li, Yaoyao Fu, Ting-Chang Chang, Yi Li, Xiang-Shui Miao, and Yuhui He
- Subjects
Electrical and Electronic Engineering ,Electronic, Optical and Magnetic Materials - Published
- 2023
3. Feasibility and Safety of Transgastric Natural Orifice Transluminal Endoscopic Surgery in the Diagnosis of Ascites of Unknown Origin
- Author
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Bo-Wen Cheng, Pei-Wei Xie, Yin-Shui Miao, and Guo-Hua Li
- Subjects
Surgery - Published
- 2023
4. Resistive Switching Characteristics of HfO x -Based Memristor by Inserting GeTe Layer
- Author
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Hua-Nan Liang, Na Bai, Lan-Qing Zou, Hua-Jun Sun, Kan-Hao Xue, Wei-Ming Cheng, Hong Lu, and Xiang-Shui Miao
- Subjects
Electrical and Electronic Engineering ,Electronic, Optical and Magnetic Materials - Published
- 2023
5. Memristive Fast-Canny Operation for Edge Detection
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Jing Tian, Hou-Ji Zhou, Han Bao, Jia Chen, Xiao-Di Huang, Jian-Cong Li, Ling Yang, Yi Li, and Xiang-Shui Miao
- Subjects
Electrical and Electronic Engineering ,Electronic, Optical and Magnetic Materials - Published
- 2022
6. A Method to Assess Glyphosate, Aminomethylphosphonic Acid and Glufosinate in Chinese Herb Samples Using a Derivatization Method and LC–MS/MS
- Author
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Zixuan Du, Jiayin Cao, Wenting Li, Xueqing Zhao, Qing Hu, Xiuhong Mao, Shui Miao, and Shen Ji
- Subjects
Organic Chemistry ,Clinical Biochemistry ,Biochemistry ,Analytical Chemistry - Published
- 2022
7. The Role of Arsenic in the Operation of Electrical Threshold Switches
- Author
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Renjie Wu, Rongchuan Gu, Tamihiro Gotoh, Zihao Zhao, Yuting Sun, Shujing Jia, Xiang Shui Miao, Min Zhu, Ming Xu, Stephen Elliott, and Zhitang Song
- Abstract
Arsenic is one of the most frequently used elements for doping conventional silicon-based semiconductors and particularly in emerging phase-change-memory (PCM) chips, yet the detailed functional mechanism as well as its experimental demonstration is still lacking in the latter in spite of its wide application. Here, we fabricate chalcogenide-based ovonic threshold switching (OTS) selectors, which are essential units for suppressing sneak currents in 3D PCM arrays, with various As concentrations. We discovered that incorporation of 20 at. % As brings a more than 100 ℃ increase in crystallization temperature, remarkably improving the switching repeatability and prolonging the device lifetime. These benefits arise from strengthened As-S bonds and sluggish atomic migration after As incorporation, as demonstrated by molecular-dynamics simulations. As a result, the addition of As reduces the leakage current by more than an order of magnitude and significantly suppresses the operational voltage drift, ultimately enabling a backend-of-the-line (BEOL)-compatible OTS selector with > 12 MA/cm2 on-current, >104 on/off ratio, ~ 10 ns speed, and a lifetime approaching 1010 cycles after 450 ℃ annealing. These performance enhancements can be explained by an As-induced increase of the band gap and of trap states, as determined by experimental photothermal deflection spectroscopy. Mechanistically, this is due to abundant defect states associated with Ge-Ge chains introduced by As-Ge and As-S bonds. These findings allow the use of precise control of the As concentration in OTS materials for improved-performance high-density 3D PCM applications.
- Published
- 2023
8. Pt/Al2O3/TaO X /Ta Self-Rectifying Memristor With Record-Low Operation Current (<2 pA), Low Power (fJ), and High Scalability
- Author
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Sheng-Guang Ren, Run Ni, Xiao-Di Huang, Yi Li, Kan-Hao Xue, and Xiang-Shui Miao
- Subjects
Electrical and Electronic Engineering ,Electronic, Optical and Magnetic Materials - Published
- 2022
9. Ultrafast and stable phase transition realized in MoTe2-based memristive devices
- Author
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Hui-Kai He, Yong-Bo Jiang, Jun Yu, Zi-Yan Yang, Chao-Fan Li, Ting-Ze Wang, De-Quan Dong, Fu-Wei Zhuge, Ming Xu, Zhi-Yi Hu, Rui Yang, and Xiang-Shui Miao
- Subjects
Mechanics of Materials ,Process Chemistry and Technology ,General Materials Science ,Electrical and Electronic Engineering - Abstract
An electric-field induced phase transition between semiconducting 2H and metallic 1T′ phases in a MoTe2 device is demonstrated for the first time. The phase transition exhibits faster switching compared with phase-change random-access memory (PCRAM), and shows more controllable switching than conventional memristive devices.
- Published
- 2022
10. Comprehensive profiling of Platycodonis radix in different growing regions using liquid chromatography coupled with mass spectrometry: from metabolome and lipidome aspects
- Author
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Weizhen Huang, Lan Lan, Heng Zhou, Jiajia Yuan, null Shui miao, Xiuhong Mao, Qing Hu, and Shen Ji
- Subjects
General Chemical Engineering ,General Chemistry - Abstract
Lipidome and metabolome profiling investigations of Platycodonis radix in different growing regions.
- Published
- 2022
11. Research progress in high entropy alloys by additive manufacturing
- Author
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WEI Shui-miao, MA Pan, JI Peng-cheng, MA Yong-chao, WANG Can, ZHAO Jian, and YU Zhi-shui
- Subjects
microstructure ,TA401-492 ,additive manufacturing ,Materials of engineering and construction. Mechanics of materials ,high-entropy alloys (heas) ,strengthening mechanism - Abstract
Based on different high-entropy alloys (HEAs) systems, the latest research progress in additive manufactured high-entropy alloys was reviewed. The rapid solidification microstructure, segregation and precipitation behaviors of high-entropy alloys fabricated by additive manufacturing with different compositions were described. Especially, the analysis was focused on the mechanical properties, deformation and strengthening mechanisms. It was pointed out that the appropriate additive manufacturing process should be selected for different high-entropy alloy systems, and the influencing factors of forming quality need to be further studied. Finally, it was proposed that high-entropy alloys with both excellent strength and high plasticity can be developed and prepared by additive manufacturing technology.
- Published
- 2021
12. Melting-Free Phase-Change Memory for Associative Learning
- Author
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Da-You Zhang, Si-Qi Wang, Zi-Jian Tang, Xiang-Shui Miao, and Yu-Hui He
- Published
- 2022
13. Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos
- Author
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Shen Ji, Shui Miao, Xiu-Hong Mao, Heng Zhou, Qing Hu, De-An Guo, Zhang Xiaoli, and Huiqin Pan
- Subjects
Insecticides ,Plants, Medicinal ,Traditional medicine ,biology ,Quality assessment ,Metabolite ,food and beverages ,Flos ,Flowers ,General Medicine ,Pesticide ,biology.organism_classification ,Acetamiprid ,Japonica ,Lonicera ,chemistry.chemical_compound ,Ingredient ,Metabolomics ,Complementary and alternative medicine ,chemistry ,Drug Discovery ,Chromatography, High Pressure Liquid ,Drugs, Chinese Herbal - Abstract
Pesticides' overuse and misuse have been reported to induce ingredient variations in herbal medicine, which is now gaining attention in the medicinal field as a form of alternative medicine. To date, available studies on pesticide-induced ingredient variations of herbal medicine are limited only on a few compounds and remain most others unexamined. In this study, a plant metabolomics-based strategy was performed to systematically explore the effects of two frequently used insecticides on the comprehensive constituents of Lonicerae Japonicae Flos (LJF), the flower buds of Lonicera japonica Thunb. Field trials were designed on a cultivating plot of L. japonica with controls and treatments of imidacloprid (IMI) and compound flonicamid and acetamiprid (CFA). Unbiased metabolite profiling was conducted by ultra-high performance liquid chromatography/quadrupole-Orbitrap mass spectrometer. After data pretreatment by automatic extraction and screening, a data matrix of metabolite features was submitted for statistical analyses. Consequently, 29 metabolic markers, including chlorogenic acids, iridoids and organic acid-glucosides were obtained and characterized. The relative quantitative assay was subsequently performed to monitor their variations across flowering developments. This is the first study that systematically explored the insecticide-induced metabolite variations of LJF while taking into account the inherent variability of flowering development. The results were beneficial for holistic quality assessment of LJF and significant for guiding scientific use of pesticides in the large-scale cultivation.
- Published
- 2021
14. In-memory sparse matrix multiplication with a low-power self-rectifying memristor array
- Author
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Jiangcong Li, Shengguang Ren, Yi Li, Ling Yang, Yingjie Yu, Run Ni, Houji Zhou, Han Bao, Yuhui He, Jia Chen, Han Jia, and Xiang Shui Miao
- Abstract
Memristor-enabled in-memory computing provides an unconventional computing paradigm to surpass the energy efficiency of von Neumann computers. However, owing to the physical limitation of the crossbar structure, although the memristor array is desirable for dense computation, it suffers from significant performance degradation in both energy and area efficiency when processing sparse linear algebra operations. In this work, we report a highly efficient in-memory sparse computing system based on the self-rectifying memristor, which originates from the joint effort of devices and algorithms and is used to solve computational modelling problems. This system is expected to have 74.9 – 19.6 TOPS / W energy efficiency for 2-bit to 8-bit sparse computation in computational modelling tasks. Compared to the previous in-memory computing hardware, our system provides over one order of magnitude improvement in energy efficiency with more than two orders of magnitude reduction in hardware overhead. This work could pave the road towards a highly efficient, unconventional computing solution for high-performance computing.
- Published
- 2022
15. Ultrafast synergistic excitation for in-situ computing
- Author
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Lei Ye, Lei Tong, Yali Bi, Yilun Wang, Xinyu Huang, Zhuiri Peng, Zheng Li, Langlang Xu, Runfeng Lin, Sihan Chen, WenHao Shi, Ming Tang, Hui Yu, Xinliang Zhang, Ping Wang, and Xiang Shui Miao
- Abstract
Nonlinear optical phenomena (NLOPs) in two-dimensional (2D) materials can be envisioned for neuromorphic functions at the device and related system level. But it has been attended rarely that transition among multi-energy states as one origin of NLOPs directly used for neuromorphic functions, which is assisted to understand nature of device-level nonlinear optical neuromorphic performance. Here we introduced a pump-probe-control technology to reveal multi-energy-state transition in multilayer molybdenum disulfide, enhancing nonlinear signals by transitions from two-photon absorption to synergistic excited states absorption and enabling an in-situ computing concept within an array of pure 2D flakes. Optical weighted average calculation and artificial neural network were realized without the fabrication of complex extrinsic structures, while preserving the femtosecond speed and femto-Joule power consumption, revealing the feasibility of pump-probe-control technology for nonlinear neuromorphic functions.
- Published
- 2022
16. In-memory Search with Memristors for Highly Efficient Similarity-Measurement-Based Data Mining
- Author
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Yi Li, Ling Yang, Xiao-Di Huang, Houji Zhou, Yingjie Yu, Han Bao, Jiangcong Li, Shengguang Ren, Feng Wang, Lei Ye, Yuhui He, Jia Chen, Guiyou Pu, Xiang Li, and Xiang Shui Miao
- Abstract
Similarity search, that is, finding similar items in massive data, is a fundamental computing problem in many fields such as data mining, and information retrieval. However, for large-scale and high-dimension data, it suffers from high computational complexity, requiring tremendous computation resources. Here, based on the one-selector-one-resistor memristors, for the first time, we propose an in-memory search (IMS) system with two innovative designs. First, by exploiting the natural distribution law of the devices resistance, a hardware local sensitive hash encoder has been designed to transform the real-valued vectors into more efficient binary codes. Second, a compact memristive ternary content addressable memory is developed to calculate the Hamming distances between the binary codes in parallel. Our IMS system demonstrated a 168× energy efficiency improvement over all-transistors counterparts in clustering and classification tasks, while achieving a software-comparable accuracy, thus providing a low-complexity and low-power solution for in-memory data mining applications.
- Published
- 2022
17. Ultrafast and stable phase transition realized in MoTe
- Author
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Hui-Kai, He, Yong-Bo, Jiang, Jun, Yu, Zi-Yan, Yang, Chao-Fan, Li, Ting-Ze, Wang, De-Quan, Dong, Fu-Wei, Zhuge, Ming, Xu, Zhi-Yi, Hu, Rui, Yang, and Xiang-Shui, Miao
- Abstract
Phase engineering of two-dimensional transition metal dichalcogenides has received increasing attention in recent years due to its atomically thin nature and polymorphism. Here, we first realize an electric-field-induced controllable phase transition between semiconducting 2H and metallic 1T' phases in MoTe
- Published
- 2022
18. Large On/Off and Rectification Ratios, Self-Compliance, High-Uniformity in Pt/Al2O3/TaOx/Ta Self-Rectifying Memristors
- Author
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Sheng-Guang Ren, Run Ni, Xiao-Di Huang, Yi Li, and Xiang-Shui Miao
- Published
- 2021
19. Comprehensive profiling of
- Author
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Weizhen, Huang, Lan, Lan, Heng, Zhou, Jiajia, Yuan, Shui Miao, Xiuhong, Mao, Qing, Hu, and Shen, Ji
- Published
- 2021
20. 2022 roadmap on neuromorphic devices and applications research in China
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Qing Wan, Changjin Wan, Huaqiang Wu, Yuchao Yang, Xiaohe Huang, Peng Zhou, Lin Chen, Tian-Yu Wang, Yi Li, Kan-Hao Xue, Yu-Hui He, Xiang-Shui Miao, Xi Li, Chenchen Xie, Houpeng Chen, Zhitang Song, Hong Wang, Yue Hao, Junyao Zhang, Jia Huang, Zheng Yu Ren, Li Qiang Zhu, Jianyu Du, Chen Ge, Yang Liu, Guanglong Ding, Ye Zhou, Su-Ting Han, Guosheng Wang, Xiao Yu, Bing Chen, Zhufei Chu, Lunyao Wang, Yinshui Xia, Chen Mu, Feng Lin, Chixiao Chen, Bojun Cheng, Yannan Xing, Weitao Zeng, Hong Chen, Lei Yu, Giacomo Indiveri, and Ning Qiao
- Subjects
General Medicine - Abstract
The data throughput in the von Neumann architecture-based computing system is limited by its separated processing and memory structure, and the mismatching speed between the two units. As a result, it is quite difficult to improve the energy efficiency in conventional computing system, especially for dealing with unstructured data. Meanwhile, artificial intelligence and robotics nowadays still behave poorly in autonomy, creativity, and sociality, which has been considered as the unimaginable computational requirement for sensorimotor skills. These two plights have urged the imitation and replication of the biological systems in terms of computing, sensing, and even motoring. Hence, the so-called neuromorphic system has drawn worldwide attention in recent decade, which is aimed at addressing the aforementioned needs from the mimicking of neural system. The recent developments on emerging memory devices, nanotechnologies, and materials science have provided an unprecedented opportunity for this aim.
- Published
- 2022
21. Integrated Metabolome and Lipidome Strategy to Reveal the Action Pattern of Paclobutrazol, a Plant Growth Retardant, in Varying the Chemical Constituents of Platycodon Root
- Author
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Lan Lan, Weizhen Huang, Heng Zhou, Jiajia Yuan, Shui Miao, Xiuhong Mao, Qing Hu, and Shen Ji
- Subjects
Platycodon ,Organic Chemistry ,Pharmaceutical Science ,Saponins ,Analytical Chemistry ,Plant Growth Regulators ,Chemistry (miscellaneous) ,Lipidomics ,platycodon root ,paclobutrazol ,metabolomic and lipidomic differences ,quantitative analysis ,plant growth regulators ,Drug Discovery ,Metabolome ,Molecular Medicine ,Physical and Theoretical Chemistry ,Chromatography, High Pressure Liquid - Abstract
Platycodon root, a medicinal food homology species which has been used in Asian countries for hundreds of years, is now widely cultivated in China. Treatment with paclobutrazol, a typical plant growth retardant, has raised uncertainties regarding the quality of Platycodon root, which have been rarely investigated. In the present study, metabolomic and lipidomic differences were revealed by ultra-high performance liquid chromatography coupled to ion mobility-quadrupole time of flight mass spectrometry (UPLC-IM-QTOF-MS). A significant decrease of platycodigenin-type saponins was observed in the paclobutrazol-treated sample. Carrying out a comprehensive quantitative analysis, the contents of total saponins and saccharides were determined to illustrate the mode of action of paclobutrazol on Platycodon root. This study demonstrated an exemplary research model in explaining how the exogenous matter influences the chemical properties of medicinal plants, and therefore might provide insights into the reasonable application of plant growth regulators.
- Published
- 2022
22. Two-dimensional silicon chalcogenides with high carrier mobility for photocatalytic water splitting
- Author
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Jun-Hui Yuan, Xiaomin Cheng, Ming Xu, Xiang-Shui Miao, Sheng Wang, Yun-Lai Zhu, Kan-Hao Xue, and Ya-Qian Song
- Subjects
Condensed Matter - Materials Science ,Electron mobility ,Materials science ,Silicon ,business.industry ,Band gap ,020502 materials ,Mechanical Engineering ,Materials Science (cond-mat.mtrl-sci) ,FOS: Physical sciences ,chemistry.chemical_element ,02 engineering and technology ,Semiconductor ,0205 materials engineering ,chemistry ,Mechanics of Materials ,Water splitting ,Optoelectronics ,General Materials Science ,Density functional theory ,business ,Absorption (electromagnetic radiation) ,Photocatalytic water splitting - Abstract
Highly-efficient water splitting based on solar energy is one of the most attractive research focuses in the energy field. Searching for more candidate photocatalysts that can work under visible-light irradiation are highly demanded. Herein, using first principle calculations based on density functional theory, we predict that the two dimensional silicon chalcogenides, i.e. SiX (X=S, Se, Te) monolayers, as semiconductors with 2.43 eV~3.00 eV band gaps, exhibit favorable band edge positions for photocatalytic water splitting. The optical adsorption spectra demonstrate that the SiX monolayers have pronounced optical absorption in the visible light region. Moreover, the band gaps and band edge positions of silicon chalcogenides monolayers can be tuned by applying biaxial strain or increasing the number of layers, in order to better fit the redox potentials of water. The combined novel electronic, high carrier mobility, and optical properties render the two dimensional SiX a promising photocatalyst for water splitting., 5 figures, 2 tables
- Published
- 2019
23. Reconfigurable Boolean Logic in Memristive Crossbar: The Principle and Implementation
- Author
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Ting-Chang Chang, Long Cheng, Xiang-Shui Miao, Yi Li, Simon M. Sze, Zhuo-Rui Wang, and Si-Yu Hu
- Subjects
Flexibility (engineering) ,Adder ,Computer science ,NAND gate ,Memristor ,Electronic, Optical and Magnetic Materials ,law.invention ,symbols.namesake ,In-Memory Processing ,law ,symbols ,Electrical and Electronic Engineering ,Crossbar switch ,Arithmetic ,XOR gate ,Von Neumann architecture - Abstract
In-memory computing based on memristive logic is considered as a prospective non von Neumann computing paradigm. In this letter, we systematically analyze the four-variable logic method and map it into the operation of two anti-serial complementary memristors in the crossbar array architecture. Arbitrary Boolean logic can be implemented within three cycles with the experimental evidence of reconfigurable NAND, NOR, and XOR logic using Pt/HfO2/TiN devices. Taking advantage of the functional flexibility, a parallel 1-bit full adder that can be realized in 8 cycles within a $\textsf {4}\times \textsf {3}$ array has been designed and verified in simulation.
- Published
- 2019
24. KTlO: a metal shrouded 2D semiconductor with high carrier mobility and tunable magnetism
- Author
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Xiang-Shui Miao, Jiafu Wang, Jun-Hui Yuan, Kan-Hao Xue, Ya-Qian Song, Li-Heng Li, and Ming Xu
- Subjects
Electron mobility ,Materials science ,Magnetism ,business.industry ,Band gap ,Doping ,02 engineering and technology ,Electronic structure ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Semiconductor ,Monolayer ,Optoelectronics ,General Materials Science ,Direct and indirect band gaps ,0210 nano-technology ,business - Abstract
Two-dimensional materials with high carrier mobility and tunable magnetism are in high demand for nanoelectronic and spintronic applications. Herein, we predict a novel two-dimensional monolayer KTlO that possesses an indirect band gap of 2.25 eV (based on HSE06 calculations) and high carrier mobility (450 cm2 V-1 s-1 for electrons and 160 cm2 V-1 s-1 for holes) by means of ab initio calculations. The electron mobility can be increased up to 26 280 cm2 V-1 s-1 and 54 150 cm2 V-1 s-1 for bilayer and trilayer KTlO, respectively. The KTlO monolayer has a calculated cleavage energy of 0.56 J m-2, which suggests exfoliation of the bulk material as a viable means for the preparation of mono- and few-layer materials. Remarkably, the KTlO monolayer demonstrates tunable magnetism and half-metallicity with hole doping, which are attributed to the novel Mexican-hat-like bands and van Hove singularities in its electronic structure. Furthermore, monolayer KTlO exhibits moderate optical absorption over the visible light and ultraviolet regions. The band gap value and band characteristics of monolayer KTlO can be substantially manipulated by biaxial and uniaxial strains to meet the requirement of various applications. All these novel properties make monolayer KTlO a promising functional material for future nanoelectronic and spintronic applications.
- Published
- 2019
25. Novel combined shield design for eye and face protection from COVID-19
- Author
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Xiu-Mei Wang, Xiu-Ling Huang, Yu-Xiang Sun, Shui-Miao Du, Zi-Kai Hua, Yi-Wen Chen, and Jin-Rong Yang
- Subjects
Face shield ,business.product_category ,Coronavirus disease 2019 (COVID-19) ,Polymers and Plastics ,Three-dimensional (3D) printing ,Mechanical Engineering ,Face (sociological concept) ,COVID-19 ,Computer security ,computer.software_genre ,World health ,Article ,Industrial and Manufacturing Engineering ,Crowds ,Mechanics of Materials ,Shield ,Business ,Goggles ,Inefficiency ,Personal protective equipment ,computer - Abstract
The World Health Organization emphasized the importance of goggles and face shields for protection of medical personnel at the outbreak of the COVID-19 pandemic. Unsurprisingly, almost all countries suffered from a critical supply shortage of goggles and face shields, as well as many other types of personal protective equipment (PPE), for a long period, owing to the lack of key medical material supplies and the inefficiency of existing fabrication methods arising from the need to avoid crowds during the outbreak of COVID-19. In this paper, we propose a novel combined shield design for eye and face protection that can be rapidly fabricated using three-dimensional printing technology. The designed prototype eye-face shield is accessible to the general public, offering more possibilities for yield improvement in PPE during emergent infectious disease events such as COVID-19.
- Published
- 2021
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26. Multilaboratory Collaborative Study of a Nontarget Data Acquisition for Target Analysis (nDATA) Workflow Using Liquid Chromatography-High-Resolution Accurate Mass Spectrometry for Pesticide Screening in Fruits and Vegetables
- Author
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Poh Leong Lim, James Pyke, Julien Parinet, Willis Chow, Heng Zhou, Nayane Udawatte, Deepika Panawennage, Douglas G. Hayward, Yoko S Johnson, Ronel Biré, Randy L. Self, Michael Conway, Erica L. Bakota, Shu-Wei Lin, Wei Jia, Danny Culberson, Dingyi Yu, Vincent Hort, Chia-Ding Liao, Paul Zomer, Yu-Ching Hung, Brian D. Eitzer, Christopher M. Lock, James S. Chang, Michael S. Filigenzi, Amadeo R. Fernández-Alba, John Schmitz, Guo-Fang Pang, Jon W. Wong, Sheldon M Williams, Lukas Vaclavik, Katerina Mastovska, Yuansheng Wu, Justin B. Renaud, Clare Ho, William K Cooke, SoYoung Kwon, Ping Wan, Kai Zhang, Shane Wyatt, Łukasz Rajski, Sara L. Nason, Qiong Wu, Mark W. Sumarah, Gregory E Mercer, Shristi Prakash, Shui Miao, Lingyun Li, Tameka Taylor, Michael Ammirata, Jean-Paul X Schirlé-Keller, Michelle Willis, Tony Chong-Ho Lam, Dan-Hui Dorothy Yang, Jian Wang, Kandalama Priyasantha, Yim-Bun Sze To, and Roland Carlson
- Subjects
quadrupole time-of-flight (QTOF) ,liquid chromatography-high-resolution accurate mass (LC-HRAM) spectrometry ,BU Contaminanten & Toxines ,Food Contamination ,easy ,rugged ,Tandem mass spectrometry ,Orbitrap ,Mass spectrometry ,Quechers ,Workflow ,law.invention ,BU Contaminants & Toxins ,data-independent acquisition (DIA) ,Tandem Mass Spectrometry ,law ,Vegetables ,effective ,quick ,Chromatography, High Pressure Liquid ,quadrupole Orbitrap (QOrbitrap) ,Chromatography ,Elution ,Pesticide Residues ,General Chemistry ,pesticides ,Pesticide ,Contamination ,Team Pesticides 2 ,nontarget data acquisition for target analysis (nDATA) ,cheap ,Fruit ,Environmental science ,safe (QuEChERS) ,False positive rate ,General Agricultural and Biological Sciences ,Chromatography, Liquid - Abstract
Nontarget data acquisition for target analysis (nDATA) workflows using liquid chromatography-high-resolution accurate mass (LC-HRAM) spectrometry, spectral screening software, and a compound database have generated interest because of their potential for screening of pesticides in foods. However, these procedures and particularly the instrument processing software need to be thoroughly evaluated before implementation in routine analysis. In this work, 25 laboratories participated in a collaborative study to evaluate an nDATA workflow on high moisture produce (apple, banana, broccoli, carrot, grape, lettuce, orange, potato, strawberry, and tomato). Samples were extracted in each laboratory by quick, easy, cheap, effective, rugged, and safe (QuEChERS), and data were acquired by ultrahigh-performance liquid chromatography (UHPLC) coupled to a high-resolution quadrupole Orbitrap (QOrbitrap) or quadrupole time-of-flight (QTOF) mass spectrometer operating in full-scan mass spectrometry (MS) data-independent tandem mass spectrometry (LC-FS MS/DIA MS/MS) acquisition mode. The nDATA workflow was evaluated using a restricted compound database with 51 pesticides and vendor processing software. Pesticide identifications were determined by retention time (tR, ±0.5 min relative to the reference retention times used in the compound database) and mass errors (δM) of the precursor (RTP, δM ≤ ±5 ppm) and product ions (RTPI, δM ≤ ±10 ppm). The elution profiles of all 51 pesticides were within ±0.5 min among 24 of the participating laboratories. Successful screening was determined by false positive and false negative rates of
- Published
- 2021
27. Simulation of Pedicle Screw Extraction Based on Galerkin Smooth Particle Meshless Method
- Author
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Xiu-Ling Huang, Yu-Xiang Sun, Xiu-Mei Wang, Hao Chen, Zi-Kai Hua, and Shui-Miao Du
- Subjects
Trabecular bone ,Materials science ,Convergence (routing) ,Applied mathematics ,Particle ,Material failure theory ,Extraction (military) ,Pedicle screw ,Galerkin method ,Finite element method - Abstract
The purpose of this study is to use the newly developed truly mesh-free method by Ls-dyna, the smooth particle Galerkin (SPG) method, to simulate the material failure process caused by the extraction of pedicle screws from the trabecular bone. The experimental and theoretical results are compared to verify the effectiveness of the SPG method. In addition, the trabecular bone material of Johnson-Cook elastoplastic material is used to compare the convergence difference between SPG and traditional finite element method in this test. The results show that the failure curve simulated by the SPG method is more reasonable, and it is not only faster than the FEM method in terms of mesh convergence but also solves the defect that the traditional FEM cannot capture the peak force.
- Published
- 2021
28. A Novel Combinatorial Shield Design for Eye and Face Protection in COVID-19
- Author
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Xiu-Mei Wang, Jin-Rong Yang, Yu-Xiang Sun, Xiu-Ling Huang, Yi-Wen Chen, Zi-Kai Hua, and Shui-Miao Du
- Subjects
Coronavirus disease 2019 (COVID-19) ,business.industry ,Computer science ,Shield ,Face (geometry) ,Computer vision ,Artificial intelligence ,business - Abstract
The World Health Organization emphasized the importance of goggles and face shields for protection of medical personnel at the outbreak of the COVID-19 pandemic. Unsurprisingly, almost all countries suffered from a critical supply shortage of goggles and face shields, as well as many other types of personal protective equipment (PPE), for a long period, owing to the lack of key medical material supplies and the inefficiency of existing fabrication methods arising from the need to avoid crowds during the outbreak of COVID-19. In this context, we propose a novel combined shield design for eye and face protection that can be rapidly fabricated using three-dimensional printing technology. The designed prototype eye–face shield is accessible to the general public , offering more possibilities for yield improvement in PPE during emergent infectious disease events such as COVID-19.
- Published
- 2020
29. A High‐Performance Ag/TiN/HfO x /HfO y /HfO x /Pt Diffusive Memristor for Calibration‐Free True Random Number Generator
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Yi‐Fan Lu, Hao‐Yang Li, Yi Li, Li‐Heng Li, Tian‐Qing Wan, Ling Yang, Wen‐Bing Zuo, Kan‐Hao Xue, and Xiang‐Shui Miao
- Subjects
Electronic, Optical and Magnetic Materials - Published
- 2022
30. Enhancing LiAlO
- Author
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Yaoyao, Fu, Boyi, Dong, Wan-Ching, Su, Chih-Yang, Lin, Kuan-Ju, Zhou, Ting-Chang, Chang, Fuwei, Zhuge, Yi, Li, Yuhui, He, Bin, Gao, and Xiang-Shui, Miao
- Abstract
Although good performance has been reported in shallow neural networks, the application of memristor synapses towards realistic deep neural networks has met more stringent requirements on the synapse properties, particularly the high precision and linearity of the synaptic analog weight tuning. In this study, a LiAlOX memristor synapse was fabricated and optimized to address these demands. By delicately tuning the initial conductance states, 120-level continuously adjustable conductance states were obtained and the nonlinearity factor was substantially reduced from 8.96 to 0.83. The significant enhancements were attributed to the reduced Schottky barrier height (SBH) between the filament tip and the electrode, which was estimated from the measured I-V curves. Furthermore, a deep neural network for realistic action recognition task was constructed, and the recognition accuracy was found to be increased from 15.1% to 91.4% on the Weizmann video dataset by adopting the above-described device optimization method.
- Published
- 2020
31. Pt
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Jun-Hui, Yuan, Li-Heng, Li, Wei, Zhang, Kan-Hao, Xue, Chundong, Wang, Jiafu, Wang, Xiang-Shui, Miao, and Xiao Cheng, Zeng
- Abstract
Electrocatalysts with high activities toward multiple electrode reactions are scarce and therefore highly sought. Here, we investigate the electrocatalytic performance of the two-dimensional (2D) Pt
- Published
- 2020
32. Optimized QuEChERS Method Combined with UHPLC-MS/MS for the Simultaneous Determination of 15 Mycotoxins in Liquorice
- Author
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Huang Xiaojing, Qing Hu, Wang Shaomin, Shen Ji, Mao Dan, and Shui Miao
- Subjects
Ochratoxin A ,Aflatoxin ,Food Contamination ,Quechers ,01 natural sciences ,Analytical Chemistry ,chemistry.chemical_compound ,0404 agricultural biotechnology ,Limit of Detection ,Tandem Mass Spectrometry ,Glycyrrhiza ,Environmental Chemistry ,Ochratoxin ,Chromatography, High Pressure Liquid ,Pharmacology ,Fumonisin B2 ,Fumonisin B1 ,Chromatography ,010401 analytical chemistry ,04 agricultural and veterinary sciences ,Mycotoxins ,040401 food science ,0104 chemical sciences ,Citrinin ,chemistry ,Agronomy and Crop Science ,Drugs, Chinese Herbal ,Food Science ,Sterigmatocystin - Abstract
In our study, a reliable and rapid analytical method for the simultaneous determination of 15 mycotoxins (aflatoxin B1, aflatoxin B2, aflatoxin G1, aflatoxin G2, alternariol, agroclavine, citrinin, diacetoxyscirpenol, deoxynivalenol, fumonisin B1, fumonisin B2, ochratoxin A, sterigmatocystin, T-2 toxin, and zearalenone) in liquorice using ultra-HPLC coupled to tandem MS was developed and validated. Due to the complex ingredients in liquorice, we chose a QuEChERS-based extraction procedure as the sample pretreatment. Meanwhile, for the first time, acetate buffer was used to replaced water, which can greatly reduce the concentration of formic acid in acetonitrile, which further reduces the extraction efficiency of impurities. The optimal combination of adsorbents is 150 mg primary secondary amine, 150 mg silica gel, 600 mg octadecylsilane, and 900 mg anhydrous magnesium sulfate. Electrospray ionization in both positive- and negative-ionization modes was applied to detect all the mycotoxins in a single run time of 15 min, with LOQs in the range of 0.125–2.5 μg/kg. The recoveries of determination obtained were in the range of 81.0–104.7%, whereas the analytes could be accurately quantified in the 0.25–625 μg/kg concentration range, with all coefficients being >0.992. Intra- and interday reproducibility were lower than 5.5 and 8.9%, respectively, for all analytical mycotoxins. The validated method was finally applied to screen mycotoxins in 31 batches of real samples collected from drugstores and hospitals in Shanghai, China. Our survey findings show that six mycotoxins were detected, including alternariol, citrinin, deoxynivalenol, fumonisin B1, ochratoxin, and zearalenone, and that the positive rate of mycotoxins was 54.8% in real samples, ranging from 3.37 to 520.6 μg/kg.
- Published
- 2018
33. Filament-to-dielectric band alignments in $$\hbox {TiO}_{2}$$ TiO 2 and $$\hbox {HfO}_{2}$$ HfO 2 resistive RAMs
- Author
-
Kan-Hao Xue, Xiang-Shui Miao, and Ze-Han Wu
- Subjects
010302 applied physics ,Resistive touchscreen ,Materials science ,Band gap ,Schottky barrier ,02 engineering and technology ,Dielectric ,021001 nanoscience & nanotechnology ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Protein filament ,Crystallography ,Ab initio quantum chemistry methods ,Modeling and Simulation ,Resistive switching ,0103 physical sciences ,Electrical and Electronic Engineering ,0210 nano-technology ,Ohmic contact - Abstract
The next-generation nonvolatile memory storage may well be based on resistive random access memories (RRAMs). $$\hbox {TiO}_{2}$$ and $$\hbox {HfO}_{2}$$ have been widely used as the resistive switching layer for RRAM devices. However, the electronic properties of the filament-to-dielectric interfaces are still not well understood yet, compared to those of the electrodes and the dielectric. In this work, we study the electronic structures of three typical filament and dielectric structures, $$\hbox {Ti}_{4}\hbox {O}_{7}/\hbox {TiO}_{2}$$ , $$\hbox {Hf}_{2}\hbox {O}_{3}/\hbox {HfO}_{2}$$ and $$\hbox {Hf}/\hbox {HfO}_{2}$$ , using ab initio calculations. We implement the GGA-1/2 method, which rectifies the band gaps of GGA through self-energy correction. Our calculation predicts an ohmic contact for the $$\hbox {Ti}_{4}\hbox {O}_{7}/\hbox {TiO}_{2}$$ interface, where the defective $$\hbox {Ti}_{4}\hbox {O}_{7}$$ phase was experimentally identified as the filament composition in $$\hbox {TiO}_{2}$$ . However, there is a finite Schottky barrier existing in either $$\hbox {Hf}_{2}\hbox {O}_{3}/\hbox {HfO}_{2}$$ interface (1.96 eV) or $$\hbox {Hf}/\hbox {HfO}_{2}$$ interface (0.61 eV), the two probable filament–dielectric configurations in hafnia-based RRAM. Our results suggest that the distinct filament-to-dielectric band alignments in $$\hbox {TiO}_{x}$$ and $$\hbox {HfO}_{x}$$ systems account for the much larger resistance window for the latter.
- Published
- 2017
34. Functionally Complete Boolean Logic in 1T1R Resistive Random Access Memory
- Author
-
Yu-Ting Su, Tian-Jian Chu, Ting-Chang Chang, Xiang-Shui Miao, Tsung-Ming Tsai, Kuan-Chang Chang, Yi Li, Simon M. Sze, Zhuo-Rui Wang, and Ya-Xiong Zhou
- Subjects
010302 applied physics ,Structure (mathematical logic) ,Computer science ,Boolean circuit ,Functional completeness ,Initialization ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Electronic, Optical and Magnetic Materials ,Resistive random-access memory ,Stateful firewall ,Logic gate ,0103 physical sciences ,State (computer science) ,Electrical and Electronic Engineering ,Arithmetic ,0210 nano-technology ,Hardware_LOGICDESIGN - Abstract
Nonvolatile stateful logic through RRAM is a promising route to build in-memory computing architecture. In this letter, a logic methodology based on 1T1R structure has been proposed to implement functionally complete Boolean logics. Arbitrary logic functions could be realized in two steps: initialization and writing. An additional read step is required to read out the logic result, which is in situ stored in the nonvolatile resistive state of the memory. Cascade problem in building larger logic circuits is also discussed. Our 1T1R logic device and operation method could be beneficial for massive integration and practical application of RRAM-based logic.
- Published
- 2017
35. Nonvolatile reconfigurable sequential logic in a HfO2 resistive random access memory array
- Author
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Ling-Yi Shih, Kuan-Chang Chang, Zhuo-Rui Wang, Simon M. Sze, Shibing Long, Ya-Xiong Zhou, Xiang-Shui Miao, Yu-Ting Su, Ting-Chang Chang, and Yi Li
- Subjects
010302 applied physics ,Sequential logic ,business.industry ,Computer science ,Logic family ,02 engineering and technology ,Parallel computing ,021001 nanoscience & nanotechnology ,01 natural sciences ,Programmable logic array ,Programmable logic device ,Programmable Array Logic ,Logic synthesis ,Logic gate ,0103 physical sciences ,General Materials Science ,0210 nano-technology ,business ,Computer hardware ,Hardware_LOGICDESIGN ,Logic optimization - Abstract
Resistive random access memory (RRAM) based reconfigurable logic provides a temporal programmable dimension to realize Boolean logic functions and is regarded as a promising route to build non-von Neumann computing architecture. In this work, a reconfigurable operation method is proposed to perform nonvolatile sequential logic in a HfO2-based RRAM array. Eight kinds of Boolean logic functions can be implemented within the same hardware fabrics. During the logic computing processes, the RRAM devices in an array are flexibly configured in a bipolar or complementary structure. The validity was demonstrated by experimentally implemented NAND and XOR logic functions and a theoretically designed 1-bit full adder. With the trade-off between temporal and spatial computing complexity, our method makes better use of limited computing resources, thus provides an attractive scheme for the construction of logic-in-memory systems.
- Published
- 2017
36. Multi-mycotoxins analysis in Pheretima using ultra-high-performance liquid chromatography tandem mass spectrometry based on a modified QuEChERS method
- Author
-
Shui Miao, Shen Ji, Wang Shaomin, Jiwei Lu, Mao Dan, and Sisi Zhang
- Subjects
Clinical Biochemistry ,Mass spectrometry ,Quechers ,01 natural sciences ,Biochemistry ,High-performance liquid chromatography ,Analytical Chemistry ,chemistry.chemical_compound ,0404 agricultural biotechnology ,Tandem Mass Spectrometry ,Liquid chromatography–mass spectrometry ,Sample preparation ,Medicine, Chinese Traditional ,Chromatography, High Pressure Liquid ,Fumonisin B2 ,Fumonisin B1 ,Chromatography ,biology ,Chemistry ,010401 analytical chemistry ,Pheretima ,04 agricultural and veterinary sciences ,Cell Biology ,General Medicine ,Mycotoxins ,biology.organism_classification ,040401 food science ,0104 chemical sciences - Abstract
A sensitive and high-throughput method was established and validated for the simultaneous determination of 22 mycotoxins in Pheretima aspergillum (E.Perrier) and Pheretima guillelmi (Michaelsen). A modified Quick Easy Cheap Effective Rugged and Safe (QuEChERS) method was used for sample preparation with recoveries ranging from 73% to 105% with relative standard deviations (RSDs) 0.99. In all cases, the intra- and inter-day precisions were lower than 6% and 10%, respectively. Matrix-matched calibration was utilized for quantification purposes to compensate for the matrix effects. Furthermore, the established method was successfully applied in 17 batches of normal real samples collected from different areas of China and 2 batches of moldy samples due to improper storage, only mold-contaminated samples were confirmed to have fumonisin B1 (FB1) and fumonisin B2 (FB2) contamination at 2.54-3.78μgkg-1. The constructed method could serve as a practical application of the UHPLC-MS/MS method for the trace analysis of multiple mycotoxins in complex matrixes, especially for those with high lipid contents.
- Published
- 2016
37. Lead-Free Halide Rb
- Author
-
Bo, Yang, Lixiao, Yin, Guangda, Niu, Jun-Hui, Yuan, Kan-Hao, Xue, Zhifang, Tan, Xiang-Shui, Miao, Ming, Niu, Xinyuan, Du, Haisheng, Song, Efrat, Lifshitz, and Jiang, Tang
- Abstract
Scintillators are widely utilized for radiation detections in many fields, such as nondestructive inspection, medical imaging, and space exploration. Lead halide perovskite scintillators have recently received extensive research attention owing to their tunable emission wavelength, low detection limit, and ease of fabrication. However, the low light yields toward X-ray irradiation and the lead toxicity of these perovskites severely restricts their practical application. A novel lead-free halide is presented, namely Rb
- Published
- 2019
38. Hot-Pressed CsPbBr
- Author
-
Weicheng, Pan, Bo, Yang, Guangda, Niu, Kan-Hao, Xue, Xinyuan, Du, Lixiao, Yin, Muyi, Zhang, Haodi, Wu, Xiang-Shui, Miao, and Jiang, Tang
- Abstract
An X-ray detector with high sensitivity would be able to increase the generated signal and reduce the dose rate; thus, this type of detector is beneficial for applications such as medical imaging and product inspection. The inorganic lead halide perovskite CsPbBr
- Published
- 2019
39. An integrated approach for global profiling of multi-type constituents: Comprehensive chemical characterization of Lonicerae Japonicae Flos as a case study
- Author
-
Jiayin Cao, Shui Miao, Xiu-Hong Mao, Qing Hu, Jiaming Liu, Lan Lan, Huiqin Pan, Heng Zhou, and Shen Ji
- Subjects
Flos ,010402 general chemistry ,Mass spectrometry ,01 natural sciences ,Biochemistry ,Chemistry Techniques, Analytical ,Analytical Chemistry ,Tandem Mass Spectrometry ,Profiling (information science) ,Medicine, Chinese Traditional ,Chromatography, High Pressure Liquid ,Chromatography ,Plants, Medicinal ,biology ,Chemistry ,Hydrophilic interaction chromatography ,010401 analytical chemistry ,Organic Chemistry ,General Medicine ,Integrated approach ,biology.organism_classification ,0104 chemical sciences ,Lonicera ,Chemical diversity ,Molecular networking ,Biological system ,Drugs, Chinese Herbal - Abstract
To fully capture the chemo-diversity of medicinal plants is very essential for understanding of their pharmacological activities and guiding scientific quality control. Aiming to facilitate chemical characterization and novel natural products discovery, the present study proposed an integrated approach based on two-dimensional liquid chromatography coupled with quadrupole-Orbitrap mass spectrometer (2D LC/Q-Orbitrap MS). An offline comprehensive two-dimensional (2D) LC system was constructed to cover and separate multi-type constituents by combining hydrophilic interaction chromatography (HILIC) and conventional reversed phase C18. A two-step mass defect filtering-induced exclusion list-data dependent acquisition was developed to increase MS/MS coverage and selectivity. Additionally, an efficient interpretation strategy, combining an automatic matching algorithm and molecular networking (MN), was introduced for rapid recognition of known compounds and efficient elucidation of unreported ones. As a case study, the integrated approach was tentatively applied for comprehensive characterization of complex multi-type components in Lonicerae Japonicae Flos (LJF), a traditional Chinese medicine. Consequently, a total of 537 compounds were characterized from LJF, including a large number of potential novel structures. It was demonstrated that the integrated approach is powerful in deep investigation on chemical diversity of medicinal plants and discovery of novel structures. Its application could also be extended for global profiling of other complicated chemical systems, such as Chinese medicinal formulas.
- Published
- 2019
40. Heteroepitaxial passivation of Cs
- Author
-
Bo, Yang, Weicheng, Pan, Haodi, Wu, Guangda, Niu, Jun-Hui, Yuan, Kan-Hao, Xue, Lixiao, Yin, Xinyuan, Du, Xiang-Shui, Miao, Xiaoquan, Yang, Qingguo, Xie, and Jiang, Tang
- Subjects
Materials for devices ,Optics and photonics ,Electronic devices ,Article ,Materials science - Abstract
X-ray detectors are broadly utilized in medical imaging and product inspection. Halide perovskites recently demonstrate excellent performance for direct X-ray detection. However, ionic migration causes large noise and baseline drift, limiting the detection and imaging performance. Here we largely eliminate the ionic migration in cesium silver bismuth bromide (Cs2AgBiBr6) polycrystalline wafers by introducing bismuth oxybromide (BiOBr) as heteroepitaxial passivation layers. Good lattice match between BiOBr and Cs2AgBiBr6 enables complete defect passivation and suppressed ionic migration. The detector hence achieves outstanding balanced performance with a signal drifting one order of magnitude lower than all previous studies, low noise (1/f noise free), a high sensitivity of 250 µC Gy air−1 cm–2, and a spatial resolution of 4.9 lp mm−1. The wafer area could be easily scaled up by the isostatic-pressing method, together with the heteroepitaxial passivation, strengthens the competitiveness of Cs2AgBiBr6-based X-ray detectors as next-generation X-ray imaging flat panels., Ionic migration degrades not only the characteristics of halide perovskite solar cells, but also those of perovskite X-ray detectors. Here Yang et al. employ heteroepitaxial BiOBr to passivate Cs2AgBiBr6 double perovskite, which suppresses ionic migration and obtain high performance X-ray detectors.
- Published
- 2018
41. Neuronal dynamics in HfO
- Author
-
Sungjun, Kim, Jia, Chen, Ying-Chen, Chen, Min-Hwi, Kim, Hyungjin, Kim, Min-Woo, Kwon, Sungmin, Hwang, Muhammad, Ismail, Yi, Li, Xiang-Shui, Miao, Yao-Feng, Chang, and Byung-Gook, Park
- Subjects
Neurons ,Silicon ,Neuronal Plasticity ,Long-Term Potentiation ,Models, Neurological ,Temperature ,Brain ,Oxides ,Oxygen ,Semiconductors ,Synapses ,Aluminum Oxide ,Humans ,Electronics ,Nerve Net ,Electrodes ,Hafnium - Abstract
We studied the pseudo-homeothermic synaptic behaviors by integrating complimentary metal-oxide-semiconductor-compatible materials (hafnium oxide, aluminum oxide, and silicon substrate). A wide range of temperatures, from 25 °C up to 145 °C, in neuronal dynamics was achieved owing to the homeothermic properties and the possibility of spike-induced synaptic behaviors was demonstrated, both presenting critical milestones for the use of emerging memristor-type neuromorphic computing systems in the near future. Biological synaptic behaviors, such as long-term potentiation, long-term depression, and spike-timing-dependent plasticity, are developed systematically, and comprehensive neural network analysis is used for temperature changes and to conform spike-induced neuronal dynamics, providing a new research regime of neurocomputing for potentially harsh environments to overcome the self-heating issue in neuromorphic chips.
- Published
- 2018
42. Salt-Gradient Approach for Regulating Capture-to-Translocation Dynamics of DNA with Nanochannel Sensors
- Author
-
Masateru Taniguchi, Ralph H. Scheicher, Yuhui He, Makusu Tsutsui, and Xiang Shui Miao
- Subjects
Fluid Flow and Transfer Processes ,Chemistry ,Process Chemistry and Technology ,Dynamics (mechanics) ,Electrical potentials ,Bioengineering ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry.chemical_compound ,Nanopore ,Present method ,Fluidics ,Nanopore sequencing ,0210 nano-technology ,Instrumentation ,DNA ,Hydrodynamic flow - Abstract
Understanding the physical mechanisms that govern the ion and fluidic transport in salt-concentration-based nanochannel/nanopore systems is essential for the potential applications in bioanalysis. One central challenge is to interpret the observed four-stage change from osmosis to the reverse one with increasing salt gradient. Here we provide a unified model that outlines the intriguing role of two competing factors, the exclusion- and diffusion-induced electrical potentials. We demonstrate theoretically a direction control of a hydrodynamic flow via the salt gradient. Based on this, we also propose a salt-gradient approach for regulating DNA motion in nanochannels that enables voltage-free single-molecule capture with a significantly low translocation speed. The present method would be used as a useful protocol to overcome the key hurdle of tailoring the capture-to-translocation dynamics of polynucleotides for nanopore sequencing.
- Published
- 2016
43. Attentional bias of soldiers with deep depression to emotional wording: an empirical research based on emotional Stroop paradigm
- Author
-
Wen-peng CAI, Hai-bo YU, Shui-miao ZHANG, Yu PAN, Guang-hui DENG, and Jin YAN
- Subjects
Stroop test ,lcsh:R5-920 ,lcsh:R ,military personnel ,lcsh:Medicine ,lcsh:Medicine (General) ,behavioral disciplines and activities ,humanities ,attention - Abstract
Objective To investigate the attentional bias of highly depressive soldiers to emotional wording with the emotion Stroop paradigm. Methods Three hundred and seventy-seven armed police soldiers completed the Symptom Checklist-90, State-Trait Anxiety Inventory and Center for Epidemiologic Studies Depression Scale (CES-D). After eliminating those with potential mental illness with SCL-90 total score over 160, positive project number over 43, and those with high trait of anxiety with TAI score over 50, 14 high depressive soldiers with CES-D score over 20 were selected to perform the emotional Stroop task based on Chinese Affective Words System. Finally, 1:1 matched case-control study was performed on 13 highly depressive soldiers and 13 mildly depressive soldiers matched for age, service length, education background and position. All the subjects were selected to finish the judgment of four blocks, including two positive blocks and two negative blocks. Results The accuracy difference and the reaction time difference in emotion blocks and emotion words between high depressive group and low depressive group were not significant (P>0.05). The reaction time of negative block was significantly longer than that of positive block in high depressive group (715.72±103.844 vs 639.42±104.101, t=2.573, P=0.024), There was no significant difference in the low depressive group (672.80±52.437 vs 669.23±62.836, t=0.435, P>0.05). Conclusions High depressive soldiers are not worse than low depressive soldiers in performance of emotional Stroop task. However, high depressive soldiers have attentional bias to negative words, while low depressive soldier have none. DOI: 10.11855/j.issn.0577-7402.2015.12.16
- Published
- 2016
44. High performance liquid chromatography-tandem mass spectrometry method for residue determination of 39 plant growth regulators in root and rhizome Chinese herbs
- Author
-
Shen Ji, Heng Zhou, Ying-xian Ma, Jiaming Liu, Li Wenting, Chayanis Sutcharitchan, Shui Miao, and Ya-jun Cui
- Subjects
Tandem mass spectrometry ,01 natural sciences ,High-performance liquid chromatography ,Analytical Chemistry ,0404 agricultural biotechnology ,Plant Growth Regulators ,Tandem Mass Spectrometry ,Radix ,Codonopsis ,Chromatography, High Pressure Liquid ,Residue (complex analysis) ,Chromatography ,Pesticide residue ,biology ,Chemistry ,010401 analytical chemistry ,Extraction (chemistry) ,Reproducibility of Results ,04 agricultural and veterinary sciences ,General Medicine ,biology.organism_classification ,040401 food science ,0104 chemical sciences ,Rhizome ,Drugs, Chinese Herbal ,Food Science - Abstract
A simple, rapid, and effective method based on salting-out extraction and LC-MS/MS techniques was developed for the determination of 39 plant growth regulator (PGR) residues in two of the most common root and rhizome Chinese herbs, Codonopsis Radix (Dangshen) and Notoginseng Radix et Rhizoma (Sanqi). The extraction process was performed with acetonitrile-water (5:1) and citrate buffer extraction salt. The performance of the method was validated in accordance with the analytical quality control criteria of SANTE/11813/2017 guidelines. Analyte recoveries of 79.49–109.41% (Dangshen) and 80.17–102.81% (Sanqi) were achieved. The limit of quantifications (LOQs) were determined with the consideration of accuracy and precision. LOQs were lower than the lowest residue limits in EU pesticide regulation (10 µg/kg) for most PGRs. Moreover, the method was successfully applied in the analysis of 35 batches of Dangshen, and 60 batches of Sanqi products. The concentration of eleven PGRs were determined in analyzed samples.
- Published
- 2020
45. Reliability, validation and norms of the Chinese version of Anxiety Sensitivity Index 3 in a sample of military personnel
- Author
-
Cun Wei, Wenpeng Cai, Yu Pan, Guanghui Deng, Wei Dong, Jin Yan, Bin Tian, and Shui-miao Zhang
- Subjects
Male ,050103 clinical psychology ,Research Validity ,Emotions ,Validity ,lcsh:Medicine ,Social Sciences ,050109 social psychology ,Test validity ,Anxiety ,Governments ,Psychology ,Ethnicities ,lcsh:Science ,Multidisciplinary ,05 social sciences ,Fear ,Research Assessment ,Anxiety Disorders ,Confirmatory factor analysis ,Military Personnel ,Convergent validity ,Physical Sciences ,Female ,medicine.symptom ,Clinical psychology ,Research Article ,Personality ,Adult ,Psychometrics ,Adolescent ,Political Science ,Research and Analysis Methods ,Skewness ,Sensitivity and Specificity ,Young Adult ,Cronbach's alpha ,medicine ,Humans ,0501 psychology and cognitive sciences ,Psychiatric Status Rating Scales ,Analysis of Variance ,lcsh:R ,Construct validity ,Biology and Life Sciences ,Reproducibility of Results ,Probability Theory ,Probability Distribution ,People and Places ,Anxiety sensitivity ,lcsh:Q ,Population Groupings ,Factor Analysis, Statistical ,Chinese People ,Armed Forces ,Mathematics - Abstract
This study aimed to explore the properties of the Chinese version of the Anxiety Sensitivity Index- 3 (ASI-3) in a sample of military personnel. Using non-probabilistic sampling, the Chinese version of the ASI-3 was administered to 3,077 valid participants aged 16 to 36 years old (M = 22.35, SD = 3.57) from nine military units. The Depression Anxiety Stress Scales-21 (DASS-21) and The State-Trait Anxiety Inventory (STAI) were used to assess the construct validity. A one-way analysis of variance was conducted to compare the differences in the services and positions of the participants. It was found that ①The indices of confirmatory factor analysis met the standard values, which supported the hypothesis of the three-factor model of the original ASI-3; ②ASI-3 was significantly associated with DASS-21 in positive ways, which indicated the high convergent validity; on the other hand, the correlation between ASI-3 and TAI was relatively low, which indicated there was an empirical discrimination between anxiety sensitivity and trait anxiety. ③The Cronbach's α coefficients were 0.926 for the total scale and 0.828-0.841 for the three subscales; ④At a cut-off score of 16, the sensitivity and specificity levels were 71.1% and 76.7%, respectively, where the sum of sensitivity and specificity becomes the maximum, accompanied with improvement of PPV and NPV; ⑤There were significant findings in the ASI and subscales among the five services and four positions. This study provides new evidence that the Chinese version of the Anxiety Sensitivity Index-3 has good validity and reliability and could be applied as an effective tool to assess anxiety sensitivity in military personnel. Our recommendations to researchers and practitioners are that the three factor model should be replicated across some different special forces and the items and constructs could be modified on Chinese culture.
- Published
- 2018
46. Qualitative screening and quantitative determination of 569 pesticide residues in honeysuckle using ultrahigh-performance liquid chromatography coupled to quadrupole-Orbitrap high resolution mass spectrometry
- Author
-
Shui Miao, Heng Zhou, Chen Ming, Shen Ji, Yi-Min Cao, Xiu-Hong Mao, Li Wenting, and Lan Lan
- Subjects
010402 general chemistry ,Quechers ,Orbitrap ,01 natural sciences ,Biochemistry ,Mass Spectrometry ,Analytical Chemistry ,law.invention ,Limit of Detection ,law ,Pesticides ,Honeysuckle ,Chromatography, High Pressure Liquid ,Detection limit ,Chromatography ,biology ,Pesticide residue ,Chemistry ,010401 analytical chemistry ,Organic Chemistry ,Pesticide Residues ,General Medicine ,Repeatability ,biology.organism_classification ,Quantitative determination ,0104 chemical sciences ,Lonicera ,Quantitative analysis (chemistry) ,Databases, Chemical ,Chromatography, Liquid - Abstract
A method for both qualitative screening and quantitative determination of 569 pesticides in honeysuckle was developed based on ultrahigh-performance liquid chromatography (UHPLC) coupled to quadrupole-Orbitrap high resolution mass spectrometry and an in-house executable compound database involving the theoretical masses of precursor and fragment ions and retention times. Different workflows were evaluated, validated and compared including Full MS-SIM, Full MS/ddMS2, Full MS/AIF and Full MS/DIA. For qualitative analysis, Full MS/DIA showed relatively low screening detection limits (SDLs) for most pesticides, but its MS2 identification seemed to be not reliable enough. Full MS/ddMS2 showed good repeatability of fragment ion recognition and less false positives. For quantitative analysis, the results of four workflows were comparable in terms of linearity and trueness, while Full MS-SIM and Full MS/ddMS2 gave better precision than the other two workflows for most pesticides at the spiking level of 0.01 mg/kg. Therefore, UHPLC-Full MS/ddMS2 was considered as the optimal workflow for both qualitative and quantitative analysis of honeysuckle samples. Pesticides were present in 75 of the 82 investigated samples, with concentrations ranging from 10.0 to 4116.9 μg/kg in some of the most severely contaminated samples.
- Published
- 2019
47. Implementation of Functionally Complete Boolean Logic and 8-Bit Adder in CMOS Compatible 1T1R RRAMs for In-Memory Computing
- Author
-
Simon M. Sze, Zhuo-Rui Wang, Kan-Hao Xue, Yu-Ting Su, Ting-Chang Chang, Kang-Sheng Yin, Yi Li, Ya-Xiong Zhou, Long Cheng, and Xiang-Shui Miao
- Subjects
010302 applied physics ,Adder ,Computational complexity theory ,Computer science ,8-bit ,02 engineering and technology ,Parallel computing ,Construct (python library) ,021001 nanoscience & nanotechnology ,01 natural sciences ,Resistive random-access memory ,symbols.namesake ,In-Memory Processing ,Logic gate ,0103 physical sciences ,symbols ,0210 nano-technology ,Von Neumann architecture - Abstract
RRAM is a promising candidate to construct in-memory computing architecture which can break through the von Neumann bottleneck. Taking advantage of the CMOS compatible 1T1R RRAM, functionally complete Boolean logics can be realized within two steps in a single unit that can suppress sneak pass problem and avoid cascading problem partially. In addition, an 8-bit pre- calculation adder with low computation complexity is designed and demonstrated experimentally to verify the feasibility and efficiency of 1T1R based in-memory computing architecture, which is applicable to future energy-efficient information processing systems.
- Published
- 2018
48. Multi-residue analysis of pesticides in traditional Chinese medicines using gas chromatography-negative chemical ionisation tandem mass spectrometry
- Author
-
Jiwei Lu, Jing Nie, Li Wenting, Heng Zhou, Shui Miao, Shen Ji, Xiu-Hong Mao, Steven J. Lehotay, and Lan Lan
- Subjects
Analyte ,Residue (complex analysis) ,Angelica sinensis ,Chromatography ,biology ,Chemistry ,Health, Toxicology and Mutagenesis ,Pesticide Residues ,Public Health, Environmental and Occupational Health ,Reproducibility of Results ,General Chemistry ,General Medicine ,Toxicology ,Quechers ,biology.organism_classification ,Tandem mass spectrometry ,Sensitivity and Specificity ,Gas Chromatography-Mass Spectrometry ,Pyrethrins ,Sample preparation ,Amine gas treating ,Gas chromatography ,Drugs, Chinese Herbal ,Food Science - Abstract
In this study, a residue analysis method for the simultaneous determination of 107 pesticides in traditional Chinese medicines (TCMs), Angelica sinensis, A. dahurica, Leonurus heterophyllus Sweet, Pogostemon cablin and Lonicera japonica Thunb., was developed using gas chromatography coupled with tandem mass spectrometry in negative chemical ionisation mode (GC-NCI-MS/MS). NCI has advantages of high sensitivity and selectivity to chemicals with electron-withdrawing groups, and yields low background interference. For sample preparation, QuEChERS (quick, easy, cheap, effective, rugged and safe) was applied. Due to the unique characteristics of TCMs, the clean-up step was optimised by adjusting amounts of primary secondary amine, C18, graphitised carbon black and silica sorbents. Validation was mainly performed by determining analyte recoveries at four different spiking concentrations of 10, 50, 100 and 200 ng g(-1), with seven replicates at each concentration. Method trueness, precision, linearity of calibration curves, lowest calibrated levels (LCLs) and matrix effects were determined to demonstrate method and instrument performance. Among the 107 pesticides tested, approximately 80% gave recoveries from 80% to 110% and 10% relative standard deviation (RSD). The LCLs for nearly all pesticides were 5 ng g(-1), and as low as 0.1 ng g(-1) for dichlofenthion, endosulfan sulphate, flumetralin, isofenphos-methyl, methyl-pentachlorophenyl sulphide and trifluralin. The results indicate that GC-NCI-MS/MS is an excellent technique for quantitative and qualitative analysis of targeted GC-amenable pesticides at ultra-trace levels, especially in complex matrices such as TCMs.
- Published
- 2015
49. Observation of carrier localization in cubic crystalline Ge
- Author
-
Hang, Qian, Hao, Tong, Ming-Ze, He, Hong-Kai, Ji, Ling-Jun, Zhou, Ming, Xu, and Xiang-Shui, Miao
- Subjects
sense organs ,Article - Abstract
The tunable disorder of vacancies upon annealing is an important character of crystalline phase-change material Ge2Sb2Te5 (GST). A variety of resistance states caused by different degrees of disorder can lead to the development of multilevel memory devices, which could bring a revolution to the memory industry by significantly increasing the storage density and inspiring the neuromorphic computing. This work focuses on the study of disorder-induced carrier localization which could result in multiple resistance levels of crystalline GST. To analyze the effect of carrier localization on multiple resistant levels, the intrinsic field effect (the change in surface conductance with an applied transverse electric field) of crystalline GST was measured, in which GST films were annealed at different temperatures. The field effect measurement is an important complement to conventional transport measurement techniques. The field effect mobility was acquired and showed temperature activation, a hallmark of carrier localization. Based on the relationship between field effect mobility and annealing temperature, we demonstrate that the annealing shifts the mobility edge towards the valence-band edge, delocalizing more carriers. The insight of carrier transport in multilevel crystalline states is of fundamental relevance for the development of multilevel phase change data storage.
- Published
- 2017
50. Nonvolatile reconfigurable sequential logic in a HfO
- Author
-
Ya-Xiong, Zhou, Yi, Li, Yu-Ting, Su, Zhuo-Rui, Wang, Ling-Yi, Shih, Ting-Chang, Chang, Kuan-Chang, Chang, Shi-Bing, Long, Simon M, Sze, and Xiang-Shui, Miao
- Abstract
Resistive random access memory (RRAM) based reconfigurable logic provides a temporal programmable dimension to realize Boolean logic functions and is regarded as a promising route to build non-von Neumann computing architecture. In this work, a reconfigurable operation method is proposed to perform nonvolatile sequential logic in a HfO
- Published
- 2017
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