1. Comparison of Acute Diffusion Tensor Imaging and Conventional Magnetic Resonance Parameters in Predicting Long-Term Outcome after Blunt Cervical Spinal Cord Injury
- Author
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Bizhan Aarabi, Jiachen Zhuo, Sudini Kuladeep, Rao P Gullapallie, Catriona Miller, Kathirkamanathan Shanmuganathan, Uttam K. Bodanapally, Jay Menakar, and Jason Adams
- Subjects
Adult ,Male ,030506 rehabilitation ,medicine.medical_specialty ,Time Factors ,Walking ,behavioral disciplines and activities ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Blunt ,Predictive Value of Tests ,medicine ,Humans ,Longitudinal Studies ,Prospective Studies ,Spinal cord injury ,Spinal Cord Injuries ,Aged ,medicine.diagnostic_test ,business.industry ,Cervical Cord ,Magnetic resonance imaging ,Recovery of Function ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Cervical spine ,Diffusion Tensor Imaging ,nervous system ,Cervical spinal cord injury ,Female ,Neurology (clinical) ,Radiology ,0305 other medical science ,business ,030217 neurology & neurosurgery ,Follow-Up Studies ,Diffusion MRI - Abstract
This prospective longitudinal study compares the ability of conventional and diffusion tensor imaging (DTI) parameters made at the cervical spinal cord injury (CSCI) site to predict long-term neurological and functional outcomes. Twenty patients with CSCI, with follow-up at 6 or 12 months, and 15 control volunteers were included. Conventional magnetic resonance imaging (MRI) and DTI parameters were measured on admission and follow-up studies. Stepwise regression analysis was performed to find relevant parameters (normalized DTI values, conventional MRI measurements, hemorrhagic contusion [HC] or non-HC [NHC]) that correlated with three primary outcome measures: patient International Standards for Neurological Classification of Spinal Cord Injury total motor score (ISNCSCI-TMS), ability to walk, and expected recovery of upper limb motor scores (ER-ULMS) at 6 or 12 months. Univariate analysis showed HC (
- Published
- 2020