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Introduction. To conduct a total assessment of carcinogenic, non-carcinogenic, and organoleptic risks to public health and cover both normalized and non-normalized pollutants of potable water, based on the results of long-term monitoring studies, it is possible using an integral indicator of chemical harmlessness of water. Material and methods. Authors studied potable water of water intakes of surface and infiltration types from potable water reservoirs and remote zones of Ufa water distribution networks. Impurities were determined by chromatography, inductively coupled plasma mass spectrometry, photometric, nephelometric, and titrimetric methods. Results. The main effect on the amount of carcinogenic risk in potable water of the surface water intake are chloroform, bromodichlethane, dichloroacetic acid, in the infiltration water intake - in addition to these compounds zinc, lead and chromium are in addition influenced. Organic compounds (phthalates, benz(a)pyrene, volatile aromatic compounds, etc.) have no effect on this type of risk due to the presence in water in low background concentrations. The identified number of individual carcinogenic risks for bromodichloroacetic acid and dichloroacetic acid according to the WHO classification corresponds to the second range. As the surface type water intake is removed from the potable water reservoir, the total carcinogenic risk of water decreases by 13-30%, and the infiltration type increases by 41-84%. Values of noncancerogenic and organoleptic risks are constant for potable water of different water intakes and correspond to recommended limit values. The excess of the maximum permissible concentrations (SanPin 1.2.3685-21) of individual substances in the potable water of the city has not been detected for the whole period of observation. In terms of the integral indicator of chemical harmlessness, the most favorable is the po-table water of the infiltration water intake, in the technology of which is mainly used the UV for decontamination of water. Conclusion. Using a risk assessment methodology complements the traditional approach to assessing water quality under modern hygiene standards. It becomes possible to evaluate the effect of pollutants of various classes on water quality when they are present together.

Lymphopenia, T cell subgroup changes, and cytokine level differences are important in the early diagnosis and treatment of Covid-19 cases and similar pandemics. We aimed to investigate the T cell, monocyte subgroups, and cytokine differences according to disease severity. A total of 46 volunteers were included in the study. According to disease status, there were three groups (control, mild, and severe). The age, gender, smoking status, temperature, heart rate and oxygen saturation, complete blood count, C-reactive protein (CRP) was noted, and flow cytometric analyses were performed for T cell and monocyte subgroups, and cytokine levels. Temperature, heart rate, SPO

Objective\ud We aimed to characterize the demographics of adults with dissociative (nonepileptic) seizures, placing emphasis on distribution of age at onset, male:female ratio, levels of deprivation, and dissociative seizure semiology.\ud \ud Methods\ud We collected demographic and clinical data from 698 adults with dissociative seizures recruited to the screening phase of the CODES (Cognitive Behavioural Therapy vs Standardised Medical Care for Adults With Dissociative Non‐Epileptic Seizures) trial from 27 neurology/specialist epilepsy clinics in the UK. We described the cohort in terms of age, age at onset of dissociative seizures, duration of seizure disorder, level of socioeconomic deprivation, and other social and clinical demographic characteristics and their associations.\ud \ud Results\ud In what is, to date, the largest study of adults with dissociative seizures, the overall modal age at dissociative seizure onset was 19 years; median age at onset was 28 years. Although 74% of the sample was female, importantly the male:female ratio varied with age at onset, with 77% of female but only 59% of male participants developing dissociative seizures by the age of 40 years. The frequency of self‐reported previous epilepsy was 27%; nearly half of these epilepsy diagnoses were retrospectively considered erroneous by clinicians. Patients with predominantly hyperkinetic dissociative seizures had a shorter disorder duration prior to diagnosis in this study than patients with hypokinetic seizures (P < .001); dissociative seizure type was not associated with gender. Predominantly hyperkinetic seizures were most commonly seen in patients with symptom onset in their late teens. Thirty percent of the sample reported taking antiepileptic drugs; this was more common in men. More than 50% of the sample lived in areas characterized by the highest levels of deprivation, and more than two‐thirds were unemployed.\ud \ud Significance\ud Females with dissociative seizures were more common at all ages, whereas the proportion of males increased with age at onset. This disorder was associated with socioeconomic deprivation. Those with hypokinetic dissociative seizures may be at risk for delayed diagnosis and treatment.

Objective\ud \ud We aimed to characterize the demographics of adults with dissociative (nonepileptic) seizures, placing emphasis on distribution of age at onset, male:female ratio, levels of deprivation, and dissociative seizure semiology.\ud Methods\ud \ud We collected demographic and clinical data from 698 adults with dissociative seizures recruited to the screening phase of the CODES (Cognitive Behavioural Therapy vs Standardised Medical Care for Adults With Dissociative Non‐Epileptic Seizures) trial from 27 neurology/specialist epilepsy clinics in the UK. We described the cohort in terms of age, age at onset of dissociative seizures, duration of seizure disorder, level of socioeconomic deprivation, and other social and clinical demographic characteristics and their associations.\ud Results\ud \ud In what is, to date, the largest study of adults with dissociative seizures, the overall modal age at dissociative seizure onset was 19 years; median age at onset was 28 years. Although 74% of the sample was female, importantly the male:female ratio varied with age at onset, with 77% of female but only 59% of male participants developing dissociative seizures by the age of 40 years. The frequency of self‐reported previous epilepsy was 27%; nearly half of these epilepsy diagnoses were retrospectively considered erroneous by clinicians. Patients with predominantly hyperkinetic dissociative seizures had a shorter disorder duration prior to diagnosis in this study than patients with hypokinetic seizures (P < .001); dissociative seizure type was not associated with gender. Predominantly hyperkinetic seizures were most commonly seen in patients with symptom onset in their late teens. Thirty percent of the sample reported taking antiepileptic drugs; this was more common in men. More than 50% of the sample lived in areas characterized by the highest levels of deprivation, and more than two‐thirds were unemployed.\ud Significance\ud \ud Females with dissociative seizures were more common at all ages, whereas the proportion of males increased with age at onset. This disorder was associated with socioeconomic deprivation. Those with hypokinetic dissociative seizures may be at risk for delayed diagnosis and treatment.

This research aims to explore the characteristics of poverty and its eradication strategies. The study employed a qualitative approach by interviewing 100 respondents who are categorized as poor in the city of Makassar. As the typology of poverty is categorized into two main groups, it was found that the most dominant typology of poverty in Makassar is the typology of cultural poverty reaching 42.3% greater than the natural rate of 27.4% and typology of structural poverty reaching 31.3%. In addition, it was discovered that cultural poverty is predominantly based on indicators that Makassar communities still have strong faith in destiny and have many family members. It is argued that the government policy in issuing the regulation is also considered to be one of the causes of structural poverty such as discrimination practices toward the poor, rampant evictions of street merchants, and lack of employment availability., peer-reviewed

The study of seismicity in the Balakend‐Zagatal region demonstrates a temporal correlation of small events in the region with the moderate events in Caucasus for the time interval of 1980 to 1990. It is shown that the processes resulting in deformation and tectonic movements of main structural elements of the Caucasus region are internal and are not related to large‐scale tectonic processes. A week dependence of the regional movements on the large‐scale motion of the lithospheric plates and microplates is apparent from another geological and geodetic data as well.