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Appliances that use electromagnetic radiation in the form of high frequency radioablation are increasingly applied in many branches of medicine and in recent times in oral surgery. They work on the same principle as the electrocauteries, with the difference that the electrocauteries use wave frequencies from 300kHz to 500kHz and the radiolayers use the frequency of wavelengths of 4MHz. This allows them a far lower energy penetration depth, less destruction and limited lateral tissue damage, without burning effect. Wound healing is faster, scarring is less, and cosmetic effect is more pronounced. During one year at the Department of Oral Surgery, a radiotherapeutic appliance is used in many oral surgery interventions. Treatment of non-contact tissues simultaneously with a hemostatic effect or pure coagulation is performed very easily and successfully. The appliance is tested when working on soft tissue of the skin and mucous membranes. With proper and professional handling any adverse effects are avoided. Special attention should be paid to patients with cardiac pacemaker and adhere to the protocol. It patient has dental implants, touching them is contraindicated while working with active electrode. Conclusion: The radiowave surgery has advantages in relation to conventional surgery wiht respect on indication areas.

The process of wound healing has a high significance in dental practice. The application of numerous antioxidants can significantly improve the process and greatly contribute to the quality of patient recovery after the intervention. In the experimental study with Wistar rats, the upper incisors were extracted and after that the solutions of coenzyme Q10 and curcumin in its free and nanoliposome-encapsulated form were applied. The extraction wounds were treated with the stated solutions for 21 days. The use of antioxidants such as Q10 and curcumin has significantly contributed to the improvement of the course of wound healing during teeth extraction in experimental animals. It needs to be emphasized that the best results were obtained by local application of coenzyme Q10 and nanoliposome-encapsulated curcumin. This application has reduced inflammation and accelerated cellular proliferation which is necessary for regeneration of damaged tissue. In addition, one of the aims of the doctoral thesis was to analyze the expression of osteopontin, a glycoprotein with important roles in inflammation and biomineralization. The immunohistochemical analysis showed a significantly lower expression in the tissues treated with nanoliposome-encapsulated antioxidants, compared to the control and other experimental groups of animals. The analysis of the level of oxidative stress parameters (MDA, AOPP, catalysis) showed that the application of antioxidants in both forms greatly contributed to the prevention of damage caused by oxygen bond production. All the results obtained in the doctoral thesis are presented in tables, graphs and are documented with images of pathohistological tissue analysis. The obtained results of the thesis can be used as a starting point in the application of these antioxidants in clinical practice in order to accelerate the process of wound healing, as well as to reduce the development of complications after teeth extraction.