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Authors: Atkins, Alana K. & Youngstrom, Eric A. Universities: The University of North Carolina at Chapel Hill Date of IRB approval: NHSR Certification UNC-CH #14-2685, October 13, 2014. Updated NHSR January 7, 2019.

Archive of materials related to a poster submission to the Future Directions Forum Conference (2019) related to analyses of the LAMS data set.

En este trabajo exploramos, mediante una encuesta online con preguntas cerradas y abiertas, tanto la experiencia como la importancia percibida de prácticas en ciencia abierta por parte de investigadoras/es de la Facultad de Psicología de la Universidad Nacional de Córdoba.

The association between ultra-processed food (UPF) and risk of cardiometabolic disorders is an ongoing concern. Different food processing-based classification systems have originated discrepancies in the conclusions among studies. To test whether the association between UPF consumption and cardiometabolic markers changes with the classification system, we used baseline data from 5636 participants (48.5% female and 51.5% male, mean age 65.1 ± 4.9) of the PREDIMED Plus (“PREvention with MEDiterranean DIet”) trial. Subjects presented with overweight or obesity and met at least three metabolic syndrome (MetS) criteria. Food consumption was classified using a 143-item food frequency questionnaire according to four food processing-based classifications: NOVA, International Agency for Research on Cancer (IARC), International Food Information Council (IFIC) and University of North Carolina (UNC). Mean changes in nutritional and cardiometabolic markers were assessed according to quintiles of UPF consumption for each system. The association between UPF consumption and cardiometabolic markers was assessed using linear regression analysis. The concordance of the different classifications was assessed with intra-class correlation coefficients (ICC3, overall = 0.51). The highest UPF consumption was obtained with the IARC classification (45.9%) and the lowest with NOVA (7.9%). Subjects with high UPF consumption showed a poor dietary profile. We detected a direct association between UPF consumption and BMI (p = 0.001) when using the NOVA system, and with systolic (p = 0.018) and diastolic (p = 0.042) blood pressure when using the UNC system. Food classification methodologies markedly influenced the association between UPF consumption and cardiometabolic risk markers.

The PREDIMED-Plus trial was supported by the European Research Council (Advanced Research grant 2014–2019; agreement #340918; granted to M.Á.M.-G.); the official Spanish institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII) through the Fondo de Investigación para la Salud (FIS) which is co-funded by the European Regional Development Fund (coordinated FIS projects led by J.S-S. and J.V., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332), and the Especial Action Project “Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus” (J.S.-S.); the Recercaixa (grant number 2013ACUP00194) (J.S.-S.). Moreover, J.S-S. gratefully acknowledges the financial support by ICREA under the ICREA Academia program; the SEMERGEN grant; Department of Health of the Government of Navarra (61/2015), the Fundació La Marató de TV (Ref. 201630.10); the AstraZeneca Young Investigators Award in Category of Obesity and T2D 2017 (D.R.); grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016; PI0137/2018), the PROMETEO/2017/017 grant from the Generalitat Valenciana, the SEMERGEN grant; grant of support to research groups 35/2011 (Balearic Islands Government; FEDER funds) (J.A.T.). R.S.-C. acknowledges financial support from the Juan de la Cierva Program Training Grants of the Spanish State Research Agency of the Spanish Ministerio de Ciencia e Innovación y Ministerio de Universidades (FJC2018-038168- I). N.B.-T. acknowledges financial support from the Juan de la Cierva Formación Program Training Grants of the Spanish State Research Agency of the Spanish Ministerio de Ciencia e Innovación y Ministerio de Universidades (FJC2018-036016-I). M.R.B.-L. was supported by “Miguel Servet Type I” program (CP15/00028) from the ISCIII-Madrid (Spain), cofinanced by the Fondo Europeo de Desarrollo Regional-FEDER. S.K.N. acknowledges financial support from the Canadian Institute for Health Research, CIHR Fellowship. J.K. was supported by the ‘FOLIUM’ programme within the FUTURMed project from the Fundación Instituto de Investigación Sanitaria Illes Balears (financed by 2017 annual plan of the sustainable tourism tax and at 50% with charge to the ESF Operational Program 2014–2020 of the Balearic Islands. C.M.-P. was financially supported by a joint grant from the Community of Madrid and the European Social Fund (grant PEJD-2019- POST/SAL-15892). The METHYL-UP project was supported by the Spanish Ministry of Science and Innovation (RTI2018-095569-B-I00, Programa de Proyectos Orientados a los Retos de la Sociedad “Projects Toward Society Challenges Program”)., The association between ultra-processed food (UPF) and risk of cardiometabolic disorders is an ongoing concern. Different food processing-based classification systems have originated discrepancies in the conclusions among studies. To test whether the association between UPF consumption and cardiometabolic markers changes with the classification system, we used baseline data from 5636 participants (48.5% female and 51.5% male, mean age 65.1 4.9) of the PREDIMEDPlus (“PREvention with MEDiterranean DIet”) trial. Subjects presented with overweight or obesity and met at least three metabolic syndrome (MetS) criteria. Food consumption was classified using a 143-item food frequency questionnaire according to four food processing-based classifications: NOVA, International Agency for Research on Cancer (IARC), International Food Information Council (IFIC) and University of North Carolina (UNC). Mean changes in nutritional and cardiometabolic markers were assessed according to quintiles of UPF consumption for each system. The association between UPF consumption and cardiometabolic markers was assessed using linear regression analysis. The concordance of the different classifications was assessed with intra-class correlation coefficients (ICC3, overall = 0.51). The highest UPF consumption was obtained with the IARC classification (45.9%) and the lowest with NOVA (7.9%). Subjects with high UPF consumption showed a poor dietary profile. We detected a direct association between UPF consumption and BMI (p = 0.001) when using the NOVA system, and with systolic (p = 0.018) and diastolic (p = 0.042) blood pressure when using the UNC system. Food classification methodologies markedly influenced the association between UPF consumption and cardiometabolic risk markers., European Research Council (ERC) European Commission #340918, Centro de Investigacion Biomedica en Red-Fisiopatologia de la Obesidad y Nutricion PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441 PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471 PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332

Llegó a Ciudad Universitaria ayer por la tarde y tiene una capacidad pico de 156 billones de operaciones con números decimales por segundo. Será utilizada para proyectos en astronomía, química, biotecnología, ciencias sociales, estadística, física e ingeniería, entre otros campos. Representa un refuerzo para las investigaciones sobre COVID-19 que vienen realizando simulaciones en los clusters de la UNC. Fue adquirida en el marco del Programa de Adquisición de Grandes Equipamientos que impulsa la Secretaría de Ciencia y Tecnología de esta universidad, e implicó una inversión de 371 mil dólares. publishedVersion Fil: Fernández, Andréz. Universidad Nacional de Córdoba. Prosecretaría de Comunicación Institucional. UNCiencia; Argentina.

En esta edición número 18, en la cual celebramos los diez años de RECIAL, a modo de homenaje, convocamos a los investigadores que conforman el Área Letras del CIFFyH - UNC, a sumarse a la celebración con un artículo que diera cuenta del recorrido de sus investigaciones durante estos diez años, sus objetivos, alcances y logros. La amplia respuesta recibida por parte de la comunidad académica del CIFFyH, que festejamos y agradecemos, nos permite desplegar en el grupo de trabajos reunidos bajo el título Dossier Aniversario, los diversos cursos que siguen los estudios que se desarrollan en el Área Letras del CIFFyH. Las investigaciones se concentran en problemas sobre estética, poética, crítica literaria, teoría del arte, filosofía, lingüística. Los trabajos en curso problematizan la diversidad sexual, lo autobiográfico, las identidades y variadas prácticas discursivas: producciones musicales y otras representaciones de la cultura popular. Los estudios literarios atienden a la literatura argentina, latinoamericana y europea; la literatura clásica o bien, contemporánea; la literatura infantil y juvenil. Otros trabajos acreditan investigaciones sobre poesía, sobre dramaturgia, estudios sobre teoría literaria, lingüística y su didáctica. Los artículos del Dossier Aniversario registran las prácticas en investigación durante el decenio acoplada a las que los equipos desarrollan en la actualidad en el CIFFyH y, en este recorrido de la memoria, emerge con justicia la vigorosa impronta dejada por algunos profesores ya retirados de la docencia-investigación que abrieron caminos en los modos de construir conocimiento y formaron equipos de investigadores que hoy se conducen marcados por su formación.

This thesis examines the past impact United Nations Command (UNC) has had on South Korean security. With South Korea’s security environment facing significant changes today, including the transfer of wartime operational control (OPCON) and the push to establish a peace regime on the Korean Peninsula, the UNC is under debate over whether it has to remain in the peninsula. This thesis seeks to analyze the impact of the UNC on South Korea’s security on a comprehensive security concept to give insight into the debate. This thesis analyzes the UNC’s influence on South Korea’s security before and after the creation of the CFC in 1978, when the UNC’s role was changed. This thesis insists that the UNC has had different effects on the comprehensive security of South Korea. Prior to 1978, the UNC had a positive impact on South Korea’s military and economic security but had a somewhat negative impact on political and diplomatic security. Since 1978, the UNC has had a limited positive impact on South Korea’s military security and has played a positive role in diplomatic security. Based on these findings, this thesis proposes that South Korea should have diplomatic initiative to resolve Korean Peninsula issues. This thesis also suggests that before establishing a peace regime, there should be no room for concessions in denuclearization negotiations with North Korea. Finally, this thesis suggests that the UNC should remain as an extension of its past positive role. Major, Republic of Korea Army Approved for public release. distribution is unlimited

El siguiente ensayo aloja dos textos: por un lado, una historia posible de la cátedra de Teoría literaria de la Escuela de Letras de la UNC, desde su creación en 1986 hasta la actualidad; por otro lado, una reflexión, guiada por esta singular historia narrada, que permita ofrecer una respuesta al siguiente interrogante: ¿qué enseñar en una materia llamada Teoría literaria? El primero de estos textos nos permitirá recorrer las transformaciones que se han operado en la cátedra y la importancia que tuvo el problema de la delimitación del objeto en su configuración. El segundo nos llevará a pensar –a partir del recorrido ya transitado por la asignatura en Córdoba– la Teoría literaria no como un espacio de adquisición de competencias demostrativas al servicio del análisis metodológico de objetos socioculturales sino como un lugar de cuestionamiento de los presupuestos científicos de la disciplina. En otras palabras, no un lugar al servicio de la metodología sino de una epistemología de la lectura como experiencia irreductible, incesante y singular cuyo avatar crítico se asienta en la persuasión más que en la demostración.

La reforma universitaria de 1918 instituye una universidad democrática al exigir un “gobierno estrictamente democrático” y que los estudiantes puedan expresar su “pensamiento propio en los cuerpos universitarios por medio de sus representantes”. Ese acto fundacional es potente: antepone la libertad de aprender sobre los intereses corporativos, establece la autonomía y anticipa el reconocimiento de la educación superior como un bien público. Reivindicando el espíritu crítico de los reformistas de 1918, en este trabajo mostramos que el acuerdo firmado en el año 2017 por el rector Hugo Juri mediante el cual la UNC pasa a formar parte del consorcio edX constituye una contrarreforma que (i) busca construir una marca internacional, (ii) precariza la educación y (iii) conlleva también una pérdida de la democracia universitaria.

El 21 de marzo de 2017, luego de un debate en el Consejo Superior, la UNC se incorporó al Consorcio edX fundado en 2012 por la Universidad de Harvard y el MIT (Massachusetts Institute of Technology). edX es un proyecto destinado a la educación "masiva, abierta y gratuita" a través de cursos online (MOOC) disponibles en el sitio edx.org. Dicho consorcio está compuesto por alrededor de 100 instituciones, entre universidades de distintas partes del mundo, empresas (como Microsoft) y organismos internacionales (FMI, Banco Mundial, BID).Algunos de los argumentos en el Consejo Superior para la incorporación de la UNC en este conglomerado incluyeron la actualización de la educación mediante la aplicación de nuevas tecnologías y de entornos educativos (cursos virtuales) sin costo y el posicionamiento de la UNC dentro del contexto mundial (medido a través de rankings internacionales). Sin embargo muchos son los elementos que nos hacen advertir que más que contribuir a garantizar el carácter público y gratuito de la enseñanza universitaria (art. 2 y 2 bis Ley 24.521 modificada en 2015), nos encontramos frente a un fenómeno encubierto de mercantilización de la educación y de pérdida de autonomía universitaria. Fil: Torrano, María Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudios sobre Cultura y Sociedad. Universidad Nacional de Córdoba. Centro de Investigaciones y Estudios sobre Cultura y Sociedad; Argentina Fil: Pagano, Miguel Maria. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina

Traditional designs for most mid-sized college classrooms discourage 1) face-to-face interaction among students, 2) instructor movement in the classroom, and 3) efficient transitions between different kinds of learning activities. An experimental classroom piloted during Spring Semester 2011 at the University of North Carolina at Chapel Hill uses clusters of stationary desks that swivel 360-degrees and aisle space to address these challenges. The findings from a study involving ten courses taught in the room suggest that there is a need for designs that not only promote quality interactions but also facilitate movement between small group work, class discussion, and lecture.

The interaction of Fas (Apo-1) and TNF receptor-1 with their respective ligands can lead to cell death. The so-called death domain, a sequence motif present in the cytoplasmic portion of the two receptors, has been identified as a critical structural element involved in signal transduction that leads to apoptosis. Here we describe several additional proteins which contain a death domain. Novel members of this family include proteins known to be implicated not only in apoptosis but also in neuron guidance.

A recently identified molecule C-terminus of Hsc70 interacting protein (CHIP) has been reported to be an E3 ubiquitin ligase collaborating with molecular chaperones for the degradation of misfolded or unfolded proteins. The physiological roles of CHIP in animal and plant development remain largely unknown. Here, we show that the knockdown of CeCHIP by RNAi and knockout by a deletion mutation arrests the development of the animal at the larval stage. CeCHIP expresses ubiquitously in all tissues but there are tissue specific variations of expression level. CeCHIP produces dose dependent phenotypes in vivo. Over expression of CHIP causes embryonic lethality, while a comparatively lower level of over expression causes locomotion and egg laying defects, and the CHIP over expressed animals form dauers at a higher temperature.