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Your search keyword '"Vierling JM"' showing total 2 results
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2 results on '"Vierling JM"'

1. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial

Author

Kwo, PY, Lawitz, EJ, McCone, J, Schiff, ER, Vierling, JM, Pound, D, Davis, MN, Galati, JS, Gordon, SC, Ravendhran, N, Rossaro, L, Anderson, FH, Jacobson, IM, Rubin, R, Koury, K, Pedicone, LD, Brass, CA, Chaudhri, E, Albrecht, JK, CRAXI, Antonio, Kwo, PY, Lawitz, EJ, McCone, J, Schiff, ER, Vierling, JM, Pound, D, Davis, MN, Galati, JS, Gordon, SC, Ravendhran, N, Rossaro, L, Anderson, FH, Jacobson, IM, Rubin, R, Koury, K, Pedicone, LD, Brass, CA, Chaudhri, E, Albrecht, JK, and Craxi, A

Subjects
HCV
Published
2010

2. Genetics of Autoimmune Liver Diseases

Author

Rosanna Asselta, Alessio Gerussi, Marco Carbone, Pietro Invernizzi, Gershwin, EM, Vierling, JM, Tanaka, A, Manns, MP, Gerussi, A, Carbone, M, Asselta, R, and Invernizzi, P

Subjects
education.field_of_study, business.industry, Concordance, Population, Autoimmune hepatitis, Disease, Autoimmune hepatiti, Primary sclerosing cholangiti, Heritability, medicine.disease, digestive system diseases, Primary sclerosing cholangitis, Increased risk, Autoimmune liver disease, Primary biliary cholangiti, Immunology, Medicine, business, education
Abstract

Autoimmune liver diseases (AILDs) have an important genetic background. This is supported by different lines of evidence, that is, clustering in families, high concordance rates in monozygotic twins, increased risk of the disease in siblings compared to general population, and association with other autoimmune conditions. In this chapter, we summarize current knowledge regarding each of the three most common AILDs (autoimmune hepatitis, AIH; primary biliary cholangitis, PBC; and primary sclerosing cholangitis, PSC); we then propose a series of possible future lines of investigation to explore the amount of heritability, which is still to be determined.

Published
2020
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