1. Clinical case: multiple endocrine neoplasia type 1 (MEN 1)
- Author
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A K Lipatenkova, L K Dzeranova, L Ya Rozhinskaya, A V Kochatkov, and Ekaterina Pigarova
- Subjects
prolactin ,proinsulin ,medicine.medical_specialty ,endocrine system diseases ,Physiology ,Endocrinology, Diabetes and Metabolism ,QD415-436 ,insulinoma ,Hypoglycemia ,Biology ,Biochemistry ,hyperparathyroidism ,Multiple endocrine neoplasia, type 1 (MEN 1) ,Endocrinology ,Internal medicine ,Internal Medicine ,medicine ,QP1-981 ,Endocrine system ,MEN1 ,Proinsulin ,Hyperparathyroidism ,Nutrition and Dietetics ,men 1 ,Public Health, Environmental and Occupational Health ,medicine.disease ,medicine.anatomical_structure ,prolactinoma ,Pancreas ,wermer syndrome ,Endocrine gland - Abstract
Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations have been described. This case demonstrates multiple formations of endocrine organs, starting non-classical with macroprolactonoma resistant to dopamine agonists therapy, other endocrine disorders developed gradually eventually: hyperparathyreoidism and hypoglycemia caused by pancreas lesions, produced proinsulin in high levels.
- Published
- 2012
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