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1. Host defence antibacterial peptides from skin secretions of Australian amphibians. The relationship between structure and activity

Author

Bowie, Jh, Wegener, Kl, Chia, Bcs, Wabnitz, Pa, John Carver, Tyler, Mj, and Wallace, Jc

Subjects
Structural Biology, General Medicine, Biochemistry
Abstract

Abstract: Peptides have been isolated and characterised from the secretions of skin glands of twenty five species of Australian amphibian. Many peptides are host defence agents, showing, for example, neuropeptide and/or antibacterial activity. This review describes the relationship between activity and structure of the antibacterial peptides, particularly the caerin and uperin groups of peptide from the genera Litoria and Uperoleia.

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