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Inge Dhamanti,1– 3 Auliya A Suwantika,4– 6 Amirah Adlia,7 Laura Navika Yamani,8,9 Fitri Yakub10 1Department of Health Policy and Administration, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia; 2Center for Patient Safety Research, Universitas Airlangga, Surabaya, Indonesia; 3School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia; 4Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia; 5Center of Excellence in Higher Education for Pharmaceutical Care Innovation, Universitas Padjadjaran, Bandung, Indonesia; 6Center for Health Technology Assessment, Universitas Padjadjaran, Bandung, Indonesia; 7Department of Pharmaceutics, School of Pharmacy, Institut Teknologi Bandung, Bandung, Indonesia; 8Division Epidemiology, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia; 9Research Center on Global Emerging and Re-Emerging Infectious Diseases, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia; 10Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Skudai, MalaysiaCorrespondence: Inge Dhamanti, Tel +62315920948, Email inge-d@fkm.unair.ac.idAbstract: The COVID-19 pandemic had a severe global impact. A range of campaigns and activities, including vaccines, are being implemented to counteract this pandemic. Using observational data, the goal of this scoping review is to identify adverse events connected with COVID-19 vaccinations. We conduct a scoping study and searched three databases from the start of the COVID-19 pandemic in 2020 through June 2022. Based on our criteria and searched keywords, the review included eleven papers in total, with the majority of the studies being conducted in developed countries. The study populations varied and included general community populations, healthcare professionals, military forces, and patients with systemic lupus and cancer. This study includes vaccines from Pfizer-BioNTech, Oxford-AstraZeneca, Sinopharm, and Moderna. The COVID-19 vaccine-related adverse events were classified into three types: local side effects, systemic side effects, and other side effects such as allergies. The adverse reactions to COVID-19 vaccines are mild to moderate in severity, with no significant influence or interference in individual daily activities and no unique patterns in cause of death among vaccine-related deaths. According to the findings of these investigations, the COVID-19 vaccine is safe to administer and induces protection. It is vital to convey accurate information to the public about vaccination side effects, potential adverse responses, and the safety level of the vaccines supplied. Multiple strategies must be implemented at the individual, organizational, and population levels to eliminate vaccine hesitance. Future studies could investigate the vaccine’s effect on people of various ages and medical conditions.Keywords: adverse effect, COVID-19 vaccines, vaccine reactions, vaccination impact