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Il contributo propone un modello di lettura e classificazione dei sistemi di Assistenza Domiciliare Integrata che pur basato sulle informazioni raccolte dal flusso del Sistema Informativo Assistenza Domiciliare SIAD riesca a rappresentare la diversità del modo in cui il servizio è erogato su uno specifico territorio superando il solo criterio del Coefficiente di Intensità Assistenziale e della quota di assistiti in carico sulla popolazione ultrssesantacinquenne.

In the current investigation, a vertically continuous casting technique was used to produce a ductile iron pipe. The ductile iron was austempered, and the tribological behavior of austempered ductile iron (ADI) was examined under various service conditions. The finding demonstrated that ADI’s tribological behaviors were significantly affected by normal loads and sliding speeds. Spheroidal graphite was preferential to be transferred from the matrix to the tribosurface in ADI under high normal loads, and high sliding speed accelerated the formation of the graphite lubricating layer on the tribosurface. Consequently, ADI’s friction coefficient dropped with the increase in normal load and sliding speed. When compared with the friction coefficient, the wear rate of ADI displayed a similar tendency in that it increased with an increase in normal load and reduced with an increase in sliding speed. The worn surface indicated that adhesive wear at low sliding speeds and abrasive wear at high sliding speeds were the primary wear mechanisms for ADI.

In recent years, there has been a significant increase related to pesticide residues in foods, which may increase the risks to the consumer of these foods with the different quality and concentrations of pesticide residues. Pesticides are used for controlling pests that reduce yields. On the other hand, it has become a major public health concern due to its toxic properties. Thus, the objective of the current study employed the application of Quick Easy Cheap Effective Rugged Safe (QuEChERS) method, in combination with gas and liquid chromatography-tandem mass spectrometric detection (GCMSMS, LCMSMS) in order to determine 137 pesticide residues (63 insecticides, 41 acaricides, 40 herbicide, 55 fungicide, nematicide, growth regulator, Chitin synthesis inhibitors, and Juvenile hormone mimics), in 801 vegetables such as 139 tomatoes, 185 peppers, 217 squash, 94 eggplants, and 166 cucumbers from different locations in Hail and Riyadh cities. The results showed that the majority of pesticide residues were detected for each of the following pesticides: acetaimpride, metalaxyl, imidaclopride, bifenthrin, pyridaben, difenoconazole, and azoxystrobien, which were repeated in the samples studied 39, 21, 11, 10, 8, 7, and 5, respectively. In addition, results observed that the tomato was the most contaminated with pesticide residues; it was contaminated with 19 compounds and was followed by pepper, cucumber, and squash, and the last commodity in the contaminated ranking was eggplant. The highest calculated estimated daily intakes (EDIs) were recorded for tomatoes which were estimated between 0.013 to 0.516 mg/kg of body weight per day (bw/day) while the lowest EDIs value was between 0.000002 to 0.0005 mg/kg of bw/day for cucumber. Results indicated that the EDIs values were lower than the acceptable daily intake (ADI) values. Results observed that the most of pesticide residues exposure in food consumption in Saudi Arabia were lower than ADIs. In addition, the highest value for health risk index (HRI) was recorded with Ethion residue in tomato, but in sweet pepper, the highest value for HRI was 127.5 in the form of fipronil residue. On the other hand, results found that the highest values of HRI were 1.54, 1.61, and 0.047 for difenoconazole, bifenthrin, and pyridaben residues in squash, eggplant, and cucumber.

Arbomex S.A. de C. V. is one of the largest worldwide manufacturers of ductile cast iron camshafts, produced by means of the phenolic urethane no-bake sand mold casting method and cold box by stack molding technology. As a result of the development of high-strength ADIs, low alloyed with vanadium, for camshaft manufacturing, previous results were published on the as-cast process and the austempering heat treatments applied to the camshafts. In the present work, camshafts of ADIs, low alloyed with 0.2 and 0.3 wt.% V, were produced at austempering temperatures of 265 and 305 °C. The performance of the new camshafts was evaluated by wear testing to ensure the function and durability of the camshafts by means of the block-on-ring wear test and a valve train system to evaluate the volume loss of material removed and the geometrical changes of the camshaft, respectively. The ADIs heat treated to 265 °C showed a microstructure constituted of fine ausferrite that aided in obtaining the highest wear resistance in the block-on ring wear test. No wear or pitting evidence was detected on the camshaft lobes and roller surfaces after the OEM test protocol during the electric spin ring test at low and high conditions for the ADI alloyed with 0.2 wt.% V heat treated at 265 °C.

Eurodoc, the European Council of Doctoral Candidates and Junior Researchers, is highly concerned to hear about the recent developments regarding the employment conditions for postdocs in Italy. This statement is a reaction to the Italian government’s plans regarding the “assegni di ricerca”, which Eurodoc strongly condemns.

In this report, the intake of food additives in Finland was estimated based on maximum permitted levels (Regulation (EC) no 1333/2008 of the European Parliament and of the Council), actual usage levels inquired from the food industry for a previous report and on the estimated proportion of product titles that contain the food additive of interest. The prevalence of each food additive in product titles was assessed using online catalogues of the two major Finnish food retail chains. As actual market shares of products were not available, our estimate was based on the proportion of product titles containing the food additive of interest among the most essential product groups. The intake of food additives among children and adults was calculated using the FAIM 2.0 tool developed by EFSA. In the intake scenario based on the proportions of product titles, the intake of only three food additives (E407, E338-343 & E450-452 and E160e) exceeded the acceptable daily intake (ADI) value among high consumers (95th percentile of intake). The mean intakes of these three food additives were much lower. A more detailed risk assessment on these food additives, with food additive concentrations based on food analyses and/or acquired from the food industry, and up-to-date, individual-level food consumption data, is needed to support potential risk management measures like food consumption recommendations., FI; pdf; efsafocalpoint@foodauthority.fi

The overall objective of the research project is to systematically map when and how acceptable daily intake (ADI) values are used as health-based benchmarks in nutrition research studies that consider the safety of low-calorie sweeteners (LCS) as it relates to measured or estimated consumption. In this mapping exercise, there are no explicit outcomes or interventions. Rather, the concept under evaluation - safe consumption levels of LCS as defined by ADI values established by authoritative bodies – implicitly contains outcomes related to safety. ADI values are unique to individual LCS, each of which is established by comprehensively reviewing toxicological data and following specific processes to conservatively establish ADI values. Results will be synthesized and integrated relative to the definition, development, and use of ADI values for LCS by authoritative bodies, such as the Joint FAO/WHO Expert Committee on Food Additives (JECFA), the U.S. Food and Drug Administration (FDA) or the European Food Safety Authority (EFSA).

This paper describes the kinship system of the Adi of Arunachal Pradesh (Padam and Minyong subgroups), focusing on its kin terminology. This system corresponds to the Omaha model defined by Lévi-Strauss, marked by generational skewing and only proscriptive matrimonial rules. It is also characterised by a remarkable profusion of terms of address indicating birth order. A comparison with the Mising system provides an opportunity to challenge some current neo-evolutionist paradigms regarding the transformations of kinship terminologies.

Made available in DSpace on 2021-06-25T12:35:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-27 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) The grinding process consists of an essential stage of manufacture that is justified by the process' ability to guarantee precise dimensions and provide an excellent surface finish. In the present study, two grinding wheels of cubic boron nitride (CBN) abrasive grains with different friability (GL and GS) were used to perform the cylindrical grinding of the austempered ductile iron (ADI). This work compared the individual performance of each wheel, with CBN GL being of low friability and CBN GS of high. During machining with three feed rates (0.5, 1.0, and 1.5 mm/min), the conventional lubri-refrigeration method was used. In the workpieces analyzed, the tests of surface roughness, roundness deviation, specific energy, G-ratio, acoustic emission, cost analysis, microhardness, confocal microscopy, and optical microscopy were applied. The tests showed that, in almost all the output parameters, the best results obtained were using the CBN GL wheel with less friability. However, in the analysis of acoustic emission and specific energy, the results presented that the GS wheel obtained the best results; as it is a more friable tool, the efforts applied during the grinding of the GS wheel are less. Also, the microstructure analyses showed that both wheels were able to carry out the process without causing changes in the workpieces' mechanical properties. The cost analysis of the inputs showed that the increase in the feed rate produces the lowest cost. Sao Paulo State Univ Julio de Mesquita Filho, Dept Mech Engn, Bauru Campus, Bauru, SP, Brazil Fed Inst Parana, Dept Control & Ind Proc, Jacarezinho Campus, Jacarezinho, Parana, Brazil Sao Paulo State Univ Julio de Mesquita Filho, Dept Elect Engn, Bauru Campus, Bauru, SP, Brazil Sao Paulo State Univ Julio de Mesquita Filho, Dept Mech Engn, Bauru Campus, Bauru, SP, Brazil Sao Paulo State Univ Julio de Mesquita Filho, Dept Elect Engn, Bauru Campus, Bauru, SP, Brazil FAPESP: 2018/22661-2 FAPESP: 2019/24933-2

Samples of ductile iron alloyed with 0.88 % Ni with a nodule count of 606, 523, and 290 nod/mm2 were obtained from sand cast plates of different thickness in the range from 8.46 to 25.4 mm. The effect of the nodule count was evaluated during the austempering process held at 285?C and austempering times of 15, 30, 45, 60, 70, and 90 min. The volume fraction of high carbon austenite increased when the nodule count increased, however, the carbon content of the high carbon austenite kept almost constant. The process window was narrow, requiring a lower austempering time when the nodule count increased. The combination of a higher nodule count and low austempering temperature allowed obtaining a fine ausferritic microstructure which led to higher Brinell hardness and tensile strength. The process window was determined by XRD measurements and it was in good agreement with the microstructural and hardness evolution as the austempering time increased.

In the present work, mechanical and microstructural properties of Austempered Ductile Iron (ADI) alloyed with Cu-Ni-Mn-Mo submitted to different hot air austempering cycles in a two-step mechanism were evaluated. In the first step, cooling and austempering were performed in an experimental hot air blower device. In the second step, the austempering was performed in a muffle furnace. Bars with O16.5 mm and 90 mm of length were austenitized in an electric resistive furnace for 90 min at 860°C. Austempering first step was performed for 10 min at 290°C, 320°C and 350°C corresponding to cycles I, II and III, respectively. Austempering second step was performed for 60 min at 380°C for all cycles. The measurements of Brinell hardness, elongation, yield strength, and ultimate tensile strength for cycle I were 288 HB, 5.0%, 840 MPa, and 988 MPa. For cycle II, the measurements were: 264 HB, 5.9%, 717 MPa, and 876 MPa. And for cycle III: 257 HB, 6.6%, 711 MPa, and 888 MPa. Microstructural analysis indicated the presence of pearlite-free ausferrite.

The aim of this study is to explore Indonesian students’ responses towards scientific argumentation with ADI learning model to physics literacy by using survey study. The sample included 100 Indonesian senior high school students (47% male and 53% female) who were studying at public school in East Java province. The Responses towards Scientific Argumentation ADI Learning Model to Physics Literacy (RT-SAPL) questionnaire was developed with Indonesian language and validated through an exploratory factor analysis of participants’ responses. For measuring the correlation among three dimensions of scale, the Pearson Correlation product moment was used. The findings indicated: the instrument used in this study had satisfactory validity and reliability. Meanwhile, the construct validities of the RT-SAPL were varying from .617 and .832 and extracting 70.655% of the variance with overall Cronbach’s alpha constant was .854. Moreover, the dimension of ADI learning model came in the first rank and followed by Scientific argumentation as well as the degree of responses towards scientific argumentation with ADI learning model to physics literacy. Finally, the findings have also indicated a significant relationship among factors of RT-SAPL.

The Food and Drug Administration (FDA) regulates artificial food colors (AFCs) in the United States. Exposure to AFCs has raised concerns about adverse behavioral effects in children. We quantified AFC exposure in women of childbearing age, pregnant women, and children and compared them to FDA and World Health Organization acceptable daily intakes (ADIs). We estimated the “typical” and “high” single-day and two-day average dietary exposure to each AFC (mg/kg/day) based on laboratory measurements and food consumption data from the 2015–2016 National Health and Nutrition Examination Survey (NHANES). We also examined whether AFC intake differed by income, education, and ethnicity. Exposure tended to be higher in children and the highest AFC exposure was found for Red No. 40. Children’s mean and 95th percentile FD&C Red No. 3 estimated intakes exceeded the ADIs in some instances. Juice drinks, soft drinks, icings, and ice cream cones were major foods contributing to children’s (

In this dissertation, the method of dimension reduction is applied to some mathematical models. Due to it, the time required to find a solution to a differential equation is reduced a few times, however, some accuracy is lost this way. Two models of heat conduction are presented, where in some part of domain the dimension is reduced from 3 or 2 to 1. Then a FVM ADI numerical scheme is justified for obtained hybrid dimension models. Some important properties of this scheme are proved. Due to nonstandard additional conditions, the classical methods are modified. A unique existence of a numerical solution is proved. Also, a fourth order partial differential equation is investigated, which was derived from a model of viscous fluid flowing through an elastic vessel. Here the dimension is reduced to 1 in the whole domain. The specification of problem is discussed along with some numerical schemes and their properties. For the problems solved in this dissertation, provided numerical experiments agree well with theoretical estimates and justify the practical usage of constructed schemes.

It was supposed that Marc Wortmann, as invited speaker, join us on CROCAD-22 either in person or virtually, and speak about rights of people with dementia from a human rights perspective. But, as you may know he suddenly pass away, on August 15, 2022, at the age of just 64. Let me tell you few words about our friend Marc from his magnificent CV. He studied Law and Art in the city of Utrecht in the Netherlands and has a master’s degree in law. He was a member of the Parliament of the Province of Utrecht and worked closely with various charities and voluntary organisations. He became Executive Director of Alzheimer Nederland in 2000. Marc joined Alzheimer’s Disease International (ADI) and was Executive Director of ADI from November 2006 till June 2017. He was responsible for external contacts, public policy (especially towards World Health Organization and United Nations) and fundraising. He was a speaker at multiple events and conferences on these topics and has published the number of articles and papers on dementia awareness and public policy. From 2017, he was CEO of Marc Wortmann Consultancy in the Netherlands, supporting chronic disease and ageing organizations globally in strategy, advocacy and fundraising. Marc was a strong advocate for people living with dementia, as well as their families and carers/ supporters. His commitment continued in recent years, through involvement in the number of projects, both at a national level in the Netherlands and at an international level. He was truly an integral part of the European and global Alzheimer’s family and we are deeply saddened by his passing. As a consultant, he was still mostly involved in the Alzheimer’s and dementia movement worldwide, but also in human rights issues and the philanthropic sector as such. He was a Board member of eight NGOs including Global Human Rights Defence. Marc was our friend, we meet numerous times, recently we were working on submitting EU project, he was always supporting our work, and was friend of people living with dementia in Croatia. We were visiting together Croatian Ministry of Health to lobby for Croatian strategy/plan to fight dementia. I remember Marc visiting Alzheimer Croatia office in Zagreb, and flying home in my jacket and wearing my scarf, which he took unintentionally in a hurry. He was plenary speaker, on 6th Croatian Congress on Alzheimer’s Disease with International Participation in Primošten, Croatia, 2012, and we awarded him with a “thank you letter”, for his great work which results that WHO named dementia as public health priority. Our heartfelt condolences go out to his wife, and to all of his family, friends and colleagues.

In this paper we aim to compare a popular numerical method with a new, recently proposed meshless approach for Heston PDE resolution. In finance, most famous models can be reformulated as PDEs, which are solved by finite difference and Monte Carlo methods. In particular, we focus on Heston model PDE and we solve it via radial basis functions (RBF) methods and alternating direction implicit. RBFs have become quite popular in engineering as meshless methods: they are less computationally heavy than finite differences and can be applied for high-order problems.

In foundry, in the development of methods for controlled cooling of castings after their solidification in sand mold, a combination of casting with heat treatment (HT), which can be called the LTO process, is proposed. The conditions for the development of the LTO process for castings from iron-carbon alloys with medium and high carbon content are considered. PTIMA of the National Academy of Sciences of Ukraine for 2018–2019 obtained a number of patents of Ukraine for methods of complementing casting and HT as varieties of the LTO process, in which Austempering of castings was used. The most convenient for LTO it is casting process in vacuum evacuated sand molds, the sand of which is easily poured out after the end of evacuation, without hindering the removal of the hot casting from the mold. For cases of adhesion of foundry paint to the surface of the casting, sand residues or local areas of the burn, especially for large castings, a method of hardening by supplying an air-sand mixture to a hot casting is proposed, as in sandblasting. A brief review of a number of works published in recent years on the influence of variable technological characteristics, mechanical properties, and microstructure on the manufacturing process of two-phase ductile cast iron (DI) type ADI is performed. Currently, there has been a significant increase in research and development around the world devoted to the production of biphasic and multiphase microand macroinhomogeneous structures containing ferrite, ausferite, bainite, martensite, carbides, carbonitrides, intermetallic compounds, and combinations thereof. Due to this, the properties of known iron-carbon alloys subjected to isothermal quenching according to traditional schemes are improved. Isothermally hardened ADI cast iron with the possibility of controlled introduction of free (proeutectoid) ferrite into the metal matrix improves the machinability of castings, which gives grounds for including the technology of such ADI in the LTO process along with other well-known methods.

In order to identify and realize the reserves of resource efficiency in the production of metal billets, the concepts of methods for combining casting and heat treatment (CHT) are considered, in particular, on the basis of high-speed knocking out of a hot casting from a sand casting mold and its immediate heat treatment, which will reduce energy consumption and the cycle of manufacturing heat-treated castings. By analogy with the traditional solution to the problem of hardening a sand mixture of a single casting mold, approaches are shown to modeling molding processes from the standpoint of the “inverse” problem of softening a sand mold mixture for quickly removing hot casting from it and further hardening of the casting according to various heat treatment schemes with increasing its mechanical properties, shown mainly by the example of isothermally hardened ductile iron, which after heat treatment is identified as Austempered Ductile Iron (ADI). An overview of the properties and advantages of bainitic cast irons among common metallic materials is given to remind and justify the technical and economic motives for creating the CHT-process and interest in the manufacture of castings with improved heat treatment properties. The CHT-process is presented as a result of research and a combination of reserves of sand molding (1), recently discovered reserves and methods of metal structure formation introduced into production (2), studies and technological processes based on which have been intensively published in the technical literature in recent years, as well as of individual treatment operations (3) for the controlled cooling of the casting with the rational use of the heat of the metal obtained from the process of its smelting. The proposed combination of knockout, treatment and heat treatment operations is analyzed as the problem of optimizing their complementarity to increase resource saving of the manufacturing process for manufacturing metal products.

Questions serve as an element that can be used to access and stimulate students’ thinking ability. This research aimed at analyzing the students’ ability to pose Higher-Order Thinking Skills (HOTS) questions during the learning process. This research was a survey research using a descriptive quantitative approach. The samples used in the research were biology education students of UIN Alauddin Makassar and Universitas Muslim Maros, South Sulawesi with the total of 92 students. The instrument used in this research was an observation sheet of questioning skills for the biology pre-service teachers. The results of this research showed that the implementations of RQA, ADI, and RQA integrated with ADI learning strategies were dominated with HOTS questions, while the learning using the conventional learning strategy was dominated with the Lower-Order Thinking Skills (LOTS) questions. The percentages of the HOTS questions in the learning using RQA, ADI, RQA integrated with ADI, and the conventional learning strategy were 60.53%, 55.71%, 64.91%, and 19.35% respectively. This finding indicates that the RQA integrated with ADI strategy contributes the significant impact in stimulating students’ ability in posing HOTS questions in the classroom.

Toxic metal and trace element levels in the ocean are increasing heterogeneously in the world, which is why it is important to assess their concentrations in organisms of fishing interest. The study of metal concentrations in different fishing grounds is of vital importance for nutritional control. In this study, two fishing grounds have been studied, in the Canary Islands and in Portugal, in each area 50 muscle samples have been taken from each of the studied species, Scomber colias, Sardina pilchardus, and Trachurus species from the Canary Islands (T. picturatus) and Portuguese (T. trachurus). The concentrations of Cd, Pb, Cr, Cu, V and Zn have been analyzed in mg / kg. Cd and Pb concentrations are higher in the species from the Canary Islands and may be linked to the African upwelling inputs, which greatly influence the metal concentrations of the species. The species with the highest concentration of metals and trace elements are influenced by the anthropogenic action of coastal pollution and the natural action of African upwelling and Saharan dust. The Cd and Pb concentrations determined in the muscle tissue of S. colias, T. picturatus, T. trachurus and S. pilchardus are below the maximum permitted limits set by the current legislation, and are, therefore, suitable for human consumption. But supporting very little nutritional percentage of the elements studied., SI

Austempered ductile iron (ADI) is a revolutionary material which has excellent mechanical properties with ease of manufacturing. Manganese addition to the ductile iron is a complex job as it may segregate at the grain boundary causing brittleness to the material. Hence, it is important to select the optimum level of manganese which may be added to the ADI without causing any adverse effect on the mechanical properties. In this study, the effect of manganese addition and heat treatment parameters on the amount of retained austenite is studied. Manganese is added in three different proportion. Microstructure and XRD analysis have shown that increasing the austempeirng temperature has resulted in the increase in volume fraction of retained austenite. Manganese addition up to 1 wt% did not cause any adverse effect on the amount of retained austenite. Higher volume fraction of retained austenite obtained at 420°C is found be 36%.

Ductile iron camshafts low alloyed with 0.2 and 0.3 wt % vanadium were produced by one of the largest manufacturers of the ductile iron camshafts in México “ARBOMEX S.A de C.V” by a phenolic urethane no-bake sand mold casting method. During functioning, camshafts are subject to bending and torsional stresses, and the lobe surfaces are highly loaded. Thus, high toughness and wear resistance are essential for this component. In this work, two austempering ductile iron heat treatments were evaluated to increase the mechanical properties of tensile strength, hardness, and toughness of the ductile iron camshaft low alloyed with vanadium. The austempering process was held at 265 and 305 °C and austempering times of 30, 60, 90, and 120 min. The volume fraction of high-carbon austenite was determined for the heat treatment conditions by XRD measurements. The ausferritic matrix was determined in 90 min for both austempering temperatures, having a good agreement with the microstructural and hardness evolution as the austempering time increased. The mechanical properties of tensile strength, hardness, and toughness were evaluated from samples obtained from the camshaft and the standard Keel block. The highest mechanical properties were obtained for the austempering heat treatment of 265 °C for 90 min for the ADI containing 0.3 wt % V. The tensile and yield strength were 1200 and 1051 MPa, respectively, while the hardness and the energy impact values were of 47 HRC and 26 J, these values are in the range expected for an ADI grade 3.

International audience; Background: The COVID-19 crisis has strained world health care systems. This study aimed to develop an innovative prediction score using clinical and biological parameters (PREDICT score) to anticipate the need of intensive care of COVID-19 patients already hospitalized in standard medical units. Methods: PREDICT score was based on a training cohort and a validation cohort retrospectively recruited in 2020 in the Marseille University Hospital. Multivariate analyses were performed, including clinical, and biological parameters, comparing a baseline group composed of COVID-19 patients exclusively treated in standard medical units to COVID-19 patients that needed intensive care during their hospitalization. Results: Independent variables included in the PREDICT score were: age, Body Mass Index, Respiratory Rate, oxygen saturation, C-reactive protein, neutrophil–lymphocyte ratio and lactate dehydrogenase. The PREDICT score was able to correctly identify more than 83% of patients that needed intensive care after at least 1 day of standard medical hospitalization. Conclusions: The PREDICT score is a powerful tool for anticipating the intensive care need for COVID-19 patients already hospitalized in a standard medical unit. It shows limitations for patients who immediately need intensive care, but it draws attention to patients who have an important risk of needing intensive care after at least one day of hospitalization.

No panorama das alterações climáticas muitas estratégias são utilizadas para reduzir o consumo de energia dos edifícios. As principais convergências no setor da construção são a nível arquitetónico e de conforto dos ambientes interiores, sabendo que a energia é um grande fator a ter em conta. Atualmente os novos edifícios possuem grandes fachadas, muitas delas envidraçadas, que geram quantidades de energia sob forma de calor. Para fazer face a estes problemas foram desenvolvidos sistema de fachadas duplas ventiladas e sistemas de sombreamento como o caso de lamelas. Este sistema permite de forma eficiente e com baixos custos energéticos reduzir a necessidade de climatização dos edifícios. Este projeto visa estudar o aproveitamento do calor gerado pelos envidraçados para climatização dos espaços interior com recurso a ventilação forçada. Para tal será necessário estudar os comportamentos térmicos das 3 fachadas duplas ventiladas (DSF) instaladas na camara experimental com recurso a 3 programas de simulação dinâmica, utilizados na modelação de escoamentos (CFD), na resposta térmica humana (HTR) e na resposta térmica de edifícios (BTR). A partir destes modelos resultaram duas simulações, uma para aplicação da mistura perfeita do ar dentro da camara e a outra para uma vertente mais prática utilizando jatos descendentes. Os resultados destas simulações foram bastante satisfatórios, comprovando que os sistemas de climatização por métodos naturais podem ser o futuro na climatização e tornar os edifícios termicamente mais eficientes com custos de produção de energia muito reduzidos. In the climate change perspective, there are many different strategies being used in order to reduce energy consumption of buildings. The main convergences in the construction industry are at an architectural level and interior environment comfort, knowing that energy is now a factor to keep in mind. Nowadays, new buildings are built with great facades, many of them in glass, that generate great amounts of energy in the form of heat. To combat these problems new techniques were developed, like double skin facades and shading systems like venetian blinds. These systems allow the reduction of the need to climatize the buildings in an efficient and low energy cost way. This project aims to study the exploitation of the heat generated by glass to use on climatization of interior spaces using forced ventilation. To do so, a study of the three double skin façades (DSF) and the experimental chamber’s thermal behavior will be necessary, using three dynamic simulation programs, used for flow modeling (CFD), human thermal response (HTR) and building thermal response (BTR). From these models, two simulations were created, one for the application of the perfect mixture of air inside the chamber and another more practical one that uses downward streams. These simulations got very satisfying results, proving that climatization systems that use natural methods can be the future and can make buildings thermally more efficient and with much lower energy costs.

A multi-residue method was applied to investigate the incidence and the concentration of ionophores and non-ionophore anticoccidials residues in poultry meat and hen eggs for the three-year period 2017-2019 in Italy. The risk related to the ingestion of such molecules was also characterized for the entire population. The average incidences of positive samples ranged from 1.35 to 9.45% while the maximum average concentration was of 4.28 μg/kg for nonionophore molecules. No uncompliant sample was recorded. The overall risk characterization related to the intake of anticoccidials trought chicken meat and eggs reveal a minor concern for consumers of all age. However, the monitoring of coccidiostates residues through official control activity in poultry meat and egg is crucial and it should be continuously conducted to ensure safety of such products and safeguard consumers̛ health.

Submitted by Marlene Santos (dossantos.ufba@gmail.com) on 2021-02-09T14:42:00Z No. of bitstreams: 1 Relatório_Final_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 1136605 bytes, checksum: a8cdf82ccd694f16c0e3677de86c57d5 (MD5) Rejected by Ana Miria Moreira (anamiriamoreira@hotmail.com), reason: Prezadas(os) gentileza anexar o resumo ao Relatório de Pesquisa e fazer o depósito novamente, para que eu possa validar no Repositório Institucional UFBA. Grata desde já. Ana Miriã Bibliotecária Biblioteca Anísio Teixeira FACED on 2021-02-10T16:46:00Z (GMT) Submitted by Marlene Santos (dossantos.ufba@gmail.com) on 2021-02-12T14:27:36Z No. of bitstreams: 2 Relatório_Final_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 1141190 bytes, checksum: b356e9ae87d94d27ebcac9d10eb24894 (MD5) Resumo_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 63490 bytes, checksum: 0a32bdfaff8e9d3880cb737e5eb05338 (MD5) Approved for entry into archive by Eleonora Guimaraes (esilva@ufba.br) on 2021-02-22T14:29:07Z (GMT) No. of bitstreams: 2 Relatório_Final_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 1141190 bytes, checksum: b356e9ae87d94d27ebcac9d10eb24894 (MD5) Resumo_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 63490 bytes, checksum: 0a32bdfaff8e9d3880cb737e5eb05338 (MD5) Made available in DSpace on 2021-02-22T14:29:07Z (GMT). No. of bitstreams: 2 Relatório_Final_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 1141190 bytes, checksum: b356e9ae87d94d27ebcac9d10eb24894 (MD5) Resumo_Pesquisa_Docência na Educação Infantil_Salvador_FACED_GEPEICI_2018_2020_repositório.pdf: 63490 bytes, checksum: 0a32bdfaff8e9d3880cb737e5eb05338 (MD5) A pesquisa Docência na Educação Infantil: um estudo sobre o trabalho pedagógico com bebês e crianças pequenas em escolas de Educação Infantil da rede municipal de ensino de Salvador, desenvolvida pelo Grupo de Estudos e Pesquisas em Educação Infantil, Crianças e Infâncias (GEPEICI) da Faculdade de Educação (FACED) da Universidade Federal da Bahia (UFBA), no período 2018-2020, sob a coordenação das professoras Marlene Oliveira dos Santos e Silvanne Ribeiro, teve como objetivo principal analisar a docência na Educação Infantil no contexto das políticas públicas, traçando o perfil das professoras e explicitando as referências e materiais que subsidiam o trabalho pedagógico com bebês e crianças pequenas. Os dados estatísticos foram construídos a partir dos microdados do Censo Escolar de 2018 do Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (INEP) e dos dados de um questionário on-line (2019) elaborado e disponibilizado na Plataforma Google Forms pela equipe da pesquisa. O referido questionário foi respondido por 93 professoras da Educação Infantil da rede municipal de ensino de Salvador. O referencial teórico-metodológico foi elaborado a partir das abordagens qualitativa-quantitativa da pesquisa em educação e de estudos teóricos sobre a Educação Infantil, as políticas públicas e o trabalho pedagógico com bebês e crianças pequenas desenvolvidos pelo Grupo de Pesquisa, no qual as pesquisadoras são filiadas. Considera-se esse estudo uma iniciativa socialmente relevante tanto para o município de Salvador/estado da Bahia como para a Universidade Federal da Bahia (UFBA), pois as pesquisas nessa área ainda são escassas e carecem de atenção. Com o resultado dessa pesquisa, espera-se fortalecer o diálogo entre a universidade e a rede municipal de ensino de Salvador, bem como difundir conhecimentos sobre a Educação Infantil e seus profissionais e apresentar indicadores importantes para formulação de novas políticas públicas para a Educação Infantil e para a melhoria das condições de trabalho dos/as docentes e da qualidade da educação das crianças de zero a seis anos de idade.

Submitted by jualmei@stj.jus.br (jualmei@stj.jus.br) on 2021-10-07T23:15:33Z No. of bitstreams: 2 decisao_inconstitucionalidade_carga_padua.pdf: 742144 bytes, checksum: 14fe373b7c128cdbe1c1bfdd442b9e23 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Approved for entry into archive by betanial@stj.jus.br (betanial@stj.jus.br) on 2021-10-08T19:03:52Z (GMT) No. of bitstreams: 2 decisao_inconstitucionalidade_carga_padua.pdf: 742144 bytes, checksum: 14fe373b7c128cdbe1c1bfdd442b9e23 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Made available in DSpace on 2021-10-08T19:03:52Z (GMT). No. of bitstreams: 2 decisao_inconstitucionalidade_carga_padua.pdf: 742144 bytes, checksum: 14fe373b7c128cdbe1c1bfdd442b9e23 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Previous issue date: 2021

Austempered ductile iron (ADI) is a revolutionary material that has the ability to replace some of the commonly used steel forgings. ADI is being used in wide range of products because of the availability of this material with relatively lesser cost and its higher strength to weight ratio. Manganese is an important alloying element added to ductile iron for improving the hardenability. However, the amount of manganese has to be carefully selected to avoid any adverse effect on the mechanical properties. In this study, impact energy and tensile properties are determined for the various austempering temperatures and manganese content. Statistical analysis is carried out to determine the relative contribution of each factors on the results. Higher impact energy is observed at the higher austempering temperature of 420°C. No adverse effect on impact energy is observed for the addition manganese up to 1 wt%. Response surface methodology is used to optimize the parameters for obtaining the superior combination of ultimate tensile strength and impact energy. Regression equations are fit to predict the impact energy and ductility of manganese alloyed ADI.

Submitted by jualmei@stj.jus.br (jualmei@stj.jus.br) on 2021-10-07T23:13:58Z No. of bitstreams: 2 acao_rescisoria_violacao_santos.pdf: 750281 bytes, checksum: 8fadd1a0d836296343f787afcfcccbc9 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Approved for entry into archive by betanial@stj.jus.br (betanial@stj.jus.br) on 2021-10-08T18:57:24Z (GMT) No. of bitstreams: 2 acao_rescisoria_violacao_santos.pdf: 750281 bytes, checksum: 8fadd1a0d836296343f787afcfcccbc9 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Made available in DSpace on 2021-10-08T18:57:24Z (GMT). No. of bitstreams: 2 acao_rescisoria_violacao_santos.pdf: 750281 bytes, checksum: 8fadd1a0d836296343f787afcfcccbc9 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Previous issue date: 2021

Submitted by phemiran@stj.jus.br (phemiran@stj.jus.br) on 2021-10-06T19:00:40Z No. of bitstreams: 2 abstract_judicial_review_lamy.pdf: 1942827 bytes, checksum: 6bca01c7abe5c59c0e2ce4d7018319a8 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Approved for entry into archive by Stephanie Moira (rsmoira@stj.jus.br) on 2021-10-07T21:52:29Z (GMT) No. of bitstreams: 2 abstract_judicial_review_lamy.pdf: 1942827 bytes, checksum: 6bca01c7abe5c59c0e2ce4d7018319a8 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Made available in DSpace on 2021-10-07T21:52:29Z (GMT). No. of bitstreams: 2 abstract_judicial_review_lamy.pdf: 1942827 bytes, checksum: 6bca01c7abe5c59c0e2ce4d7018319a8 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Previous issue date: 2021

Submitted by phemiran@stj.jus.br (phemiran@stj.jus.br) on 2021-09-30T19:09:48Z No. of bitstreams: 2 stf_utilizacao_amianto_silva.pdf: 539112 bytes, checksum: c8c5aee20d8aa38b212d2affbc7ec23d (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Approved for entry into archive by Stephanie Moira (rsmoira@stj.jus.br) on 2021-09-30T20:06:12Z (GMT) No. of bitstreams: 2 license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) stf_utilizacao_amianto_silva.pdf: 539112 bytes, checksum: c8c5aee20d8aa38b212d2affbc7ec23d (MD5) Made available in DSpace on 2021-09-30T20:06:12Z (GMT). No. of bitstreams: 2 license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) stf_utilizacao_amianto_silva.pdf: 539112 bytes, checksum: c8c5aee20d8aa38b212d2affbc7ec23d (MD5) Previous issue date: 2021

ilustraciones, fotografias, graficas, mapas La lucha frente al problema de las drogas en el mundo se ha enmarcado bajo el principio de una confrontación integral y global. Es así como a lo largo de la cadena que conforma el narcotráfico se han generado estrategias políticas, sociales, militares y económicas para hacerle frente, las cuales van desde las políticas de erradicación, hasta las campañas de prevención al consumo y en otros escenarios la implantación de marcos legales para el consumo de algunas substancias y derivados. Y es en el principio de la cadena, en el cultivo, donde muchos países han buscado hacer frente y los esfuerzos internacionales se han concentrado, desde estrategias militares y coercitivas a las comunidades y actores, hasta generar dinámicas sociales y productivas en los cultivadores, para lograr la sustitución de los cultivos de usos ilícitos por otra clase de cultivos o actividades productivas y medio ambientales; en Colombia con una historia de más de 30 años en este proceso, y con la firma del acuerdo de paz una nueva esperanza para la sustitución integral se apuesta desde el PNIS. Es allí donde se desarrolla el objeto de este estudio, analizando el Desarrollo Alternativo y el marco de implementación del PNIS en el caso de la región del Catatumbo en el municipio de Tibú desde la capacidad de agencia e incidencia de la comunidad de la vereda Puerto las Palmas para el periodo 2016 – 2019, periodo previo e inicial de la implementación del PNIS. Mediante el enfoque de análisis y desarrollo institucional – ADI- de Ostrom, junto con el análisis del Ciclo del Incumplimiento (Gutierrez F. , 2020) y las formas de resistencia (Lobo & Velez, 2020) se analiza la articulación comunal que se generó previo a la firma de los acuerdos de sustitución y en su implementación internamente como comunidad y frente a los otros actores participantes de este programa en la vereda. Metodológicamente el trabajo se realizó desde un enfoque cualitativo partiendo del análisis documental, trabajo en terreno con la comunidad de la Vereda y realización de entrevistas. (Texto tomado de la fuente) The fight against the drug problem in the world has been framed under the principle of a comprehensive and global confrontation. This is how throughout the chain that makes up drug trafficking, political, social, military and economic strategies have been generated to deal with it, which range from eradication policies to drug prevention campaigns and in other scenarios the implementation of legal frameworks for the consumption of some substances and derivatives. And it is at the beginning of the chain, in cultivation, where many countries have sought to confront and international efforts have been concentrated, from military and coercive strategies to communities and actors, to generating social and productive dynamics in growers, to achieve the substitution of illicit crops for other types of crops or productive and environmental activities; in Colombia, with a history of more than 30 years in this process, and with the signing of the peace agreement, a new hope for comprehensive replacement is bet from the PNIS. It is there where the object of this study is developed, analyzing the implementation of one of the components of the fight against drugs: Alternative Development and the implementation framework of the PNIS in the case of the Catatumbo region in the municipality of Tibú, Puerto las Palmas for the period 2016 - 2019. Through the analysis and institutional development approach - ADIof Ostrom, together with the analysis of the Cycle of Non-compliance (Gutierrez F., 2020) and the forms of resistance (Lobo & Velez, 2020 ) the communal articulation that was generated prior to the signing of the substitution agreements and its implementation internally as a community and in front of the other actors participating in this program in the village is analyzed. Methodologically, the work was carried out from a qualitative approach based on documentary analysis, field work with the community and conducting interviews Maestría Magíster en Políticas Públicas El proceso metodológico tomado para esta investigación es de tipo cualitativo, según el cual no se hace énfasis únicamente en los datos, sino también en las percepciones y significados, lo cual permite interpretar a lo rural y lo urbano como realidades percibidas, que se constituyen en una construcción social, por las preferencias de la población (Paniagua & Hoggart, 2020). Igualmente, para el desarrollo de la investigación, y dadas las condiciones sociales, ambientales y de orden público del área de estudio, la propuesta debió ajustarse acorde con las posibilidades de acceso a las veredas y de información disponible sobre el municipio de Tibu y la vereda de Puerto las Palmas.

Following a request from the European Commission, the Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of astaxanthin when used as a novel food in food supplements at maximum levels of 8 mg/day, taking into account the overall cumulative intake of astaxanthin from all food sources. In 2014, the NDA Panel assessed the safety of the novel astaxanthin-rich ingredient derived from microalgae Haematococcus pluvialis in the context of an application submitted under Regulation (EC) No 258/1997. In that opinion, the NDA Panel considered that the acceptable daily intake (ADI) for astaxanthin was 0.034 mg/kg body weight (bw) set by the EFSA FEEDAP Panel in 2014. In 2019, the FEEDAP Panel adopted an opinion which concerned the renewal of the authorisation of dimethyldisuccinate-astaxanthin and a new use of the additive for crustaceans and other fish than salmonids. In that assessment, the FEEDAP Panel derived a new ADI of 0.2 mg astaxanthin/kg bw which replaced the ADI of 0.034 mg/kg bw established in 2014. By taking into account an updated exposure assessment for astaxanthin from the background diet (fish and crustaceans) in combination with 8 mg from food supplements, the NDA Panel concludes that (i) such combined exposure to astaxanthin is safe for adults, (ii) 14 to

Austempered Ductile Iron (ADI) is widely implemented to achieve lightweight and optimized components in power transmissions (e.g., internal gear in planetary stages), by substituting steel castings or a combination of Ductile Iron and steel-assembled structures. In this paper, the contact fatigue of two ADI grades (ADI J/S900-8, ADI J/S1200-3) is investigated by disk-on-disk tests. The disk-on-disk contact is an analogy model of the tooth contact and represents the tribological conditions at a specific point on the path of contact. The experimental results cover the endurance limit as well as the short time fatigue behavior for both ADI variants. In addition, the pitting characteristics and microstructural changes are analyzed in order to get a further understanding of the fatigue behavior of ADI.

The paper analyzes the concurrent competence to legislate defined on the art. 24, XII, of the Brazilian Federal Constitution of 1988 (CF / 1988), comparing decisions of the Supreme Federal Court (STF) in times of normality and in times of crisis, as is the moment experienced, in the face of the COVID-19 pandemic. The judgments mentioned refer to the precautionary measure in Direct Unconstitutionality Action (ADI) 6341 and in the ADI 3937, both referring to the defense and protection of health. Methodologically, the study is qualitative, having as sources the bibliographic and documentary survey, especially the jurisprudential research. It is concluded that the court’s position on the concurrent competence to legislate defined on the art. 24, XII, of the CF / 1988, remained the same in the analyzed judgments

International audience; To study the influence of the microstructure of cast iron on the adhesion of an epoxy coating, ferritic, pearlitic and austempered samples were prepared in as-received, polished and oxidized states. A pull-off test (dry adhesion) was performed before immersing in water while the cross-cut test was made after 24 days of exposition in distilled water (wet adhesion). X-rays were combined with optical microscopy (LOM) and scanning electron microscopy (SEM) for surface analysis. The adhesion of the epoxy coating on the cast iron surface firstly depends on the roughness of the surface; polished samples showed high adherence by comparison with as-received samples. On the oxidized samples, the surface oxide significantly improves the adhesion of the coating in both dry and wet states for all three sample microstructure. The presence of carbide in the structure was observed to decrease adherence.

This aims of the study to compare the cognitive learning outcomes of students who learned with Argument Driven Inquiry-Scaffolding (ADI-S) and Driven Argument Inquiry (ADI) with different scientific reasoning abilities. This research is a quasy experimental design. The instruments were used cognitive learning outcomes test and the test of scientific reasoning abilities. Data were analyzed using two way ANCOVA (2x2 factorial). The results showed: (1) learned with ADI-S on the reaction rate material get cognitive learning outcomes higher than learned with ADI, (2) student with high scientific reasoning abilities have better cognitive learning outcomes rather student with low scientific reasoning abilities both in ADI-S’s class and ADI’s class. Key Words: ADI; ADI-S; scientific reasoning abilities; cognitive learning outcomes Abstrak: Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar kognitif siswa yang dibelajarkan menggunakan model Argument Driven Inquiry-Scaffolding (ADI-S) dan model Argument-Driven Inquiry (ADI) dengan kemampuan penalaran ilmiah berbeda. Rancangan penelitian yang digunakan adalah quasy eksperimental design. Instrumen yang digunakan yaitu tes hasil belajar kognitif dan tes kemampuan penalaran ilmiah. Data dianalisis menggunakan ANCOVA dua jalur (faktorial 2x2). Hasil analisis menunjukkan: (1) pembelajaran dengan model ADI-S pada materi laju reaksi memberikan hasil belajar kognitif yang lebih tinggi jika dibandingkan dengan model ADI, (2) siswa dengan kemampuan penalaran ilmiah tinggi memberikan hasil belajar kognitif lebih tinggi dibandingkan kemampuan penalaran ilmiah rendah baik pada kelas ADI-S maupun ADI. Kata kunci: ADI; ADI-S; kemampuan penalaran ilmiah; hasil belajar kognitif

In the work here presented, the high performance of ceramic insert tools in milling of ADI 1000 iron casting is analyzed. Austempered ductile irons (ADI) are ductile iron castings with strength and mechanical properties enhanced after specific heat treatment, achieving 1000 MPa or even more. Sintered carbide tools are state of the art in many industrial applications, including iron casting machining, but ceramic inserts are a feasible and promising option since cutting speed can be improved by 5 or even 10 times. A complete testing campaign was performed, starting with coated sintered carbides and aiming at the use of whisker reinforced Al2O3 ceramics and Si3N4 tools. The two most important conclusions are as follows: firstly, that the milling type so-called up-milling (or conventional) is more recommended than down-milling, also known as climb milling, and secondly, that dry machining enhances ceramics performance in comparison with using emulsion coolants (oil in water). Finally, results regarding economic aspects were analyzed based on the tools cost-performance ratio.

A mathematical model of austenite - bainite transformation in austempered ductile cast iron has been presented. The model is based on a model developed by Bhadeshia [1, 2] for modelling the bainitic transformation in high-silicon steels with inhibited carbide precipitation. A computer program has been developed that calculates the incubation time, the transformation time at a preset temperature, the TTT diagram and carbon content in unreacted austenite as a function of temperature. Additionally, the program has been provided with a module calculating the free energy of austenite and ferrite as well as the maximum driving force of transformation. Model validation was based on the experimental research and literature data. Experimental studies included the determination of austenite grain size, plotting the TTT diagram and analysis of the effect of heat treatment parameters on the microstructure of ductile iron. The obtained results show a relatively good compatibility between the theoretical calculations and experimental studies. Using the developed program it was possible to examine the effect of austenite grain size on the rate of transformation.

In this work the percent dimensional change (DC%) and its dispersion in high silicon Ductile Iron with ADI and Dual-Phase-ADI structures obtained through heat treatment starting from different as-cast microstructures, was studied. Specimens were obtained from three different melts with Si content ranging from 3.1 to 4.2%. Dual-Phase-ADI structures were obtained using special heat treatment, starting from as-cast structures. Regarding dimensional change, DC% in ADI and Dual-Phase-ADI decrease as Si% and the proportion of ferrite phase in as-cast specimens increased. On the other hand, DC% increased with austenitizing temperature and ausferrite content in the final microstructure. A fuzzy model to predict DC% in ADI parts was adapted to include DC% prediction in Dual-Phase-ADI. The fuzzy model allowed to predict the DC% for ADI and Dual-Phase-ADI parts with an root mean square

High complexity of the physical and chemical processes occurring in liquid metal is the reason why it is so difficult, impossible even sometimes, to make analytical models of these phenomena. In this situation, the use of heuristic models based on the experimental data and experience of technicians is fully justified since, in an approximate manner at least, they allow predicting the mechanical properties of the metal manufactured under given process conditions. The study presents a methodology applicable in the design of a heuristic model based on the formalism of the logic of plausible reasoning (LPR). The problem under consideration consists in finding a technological variant of the process that will give the desired product parameters while minimizing the cost of production. The conducted tests have shown the effectiveness of the proposed approach.

The purpose of this study was to determine experimentally the wear properties of 5 groups of iron-based alloys used in the mining and transport machines exposed to the action of a hard abrasive material. The groups of materials to be examined included austempered ductile irons (ADI), steels and cast steel designed for quenching and tempering and for surface hardening, hard-wearing hardened steels and structural steels. The wear tests were carried out on a disc-on-disc test rig. The test samples were examined under conditions of sliding mating, while the leading destructive process was microcutting of the surface with loose corundum grain. The loss of mass of the examined samples was measured as a parameter characterizing the wear. Base on it, other wear coefficients were determined, for example the volume loss, the intensity of wear and the wear rate. The volume loss values determined were presented as a function of the strength and the initial hardness. Based on the results obtained, it was found that the hardened steel and ADI had comparable wear properties, while the ADI surface was strengthened probably as a result of the transition of austenite into martensite and the impact of the deformation of the graphite contained in ADI on the abrasive wear of the surface.

The aim of the research was to define changes in the content of NO3¯ determined by the environment and processing in products from five cultivars of carrot, orange in colour. Besides this, in the research, the human intake of toxic compounds found in processed foods was also assayed. All the processed foods were produced at laboratory scale compliant with the applicable guidelines and norms. The content of nitrates in processed foods depended significantly on the genetic conditions of material and on the processing method. Of all the cultivars under study, ‘Karotan’ was least applicable to processing since, irrespective of the processing method, the lowest decrease in nitrates was reported for that cultivar. The consumption of processed foods from the cultivars of carrot studied is not hazardous to consumer health, since the value of the ADI in adult, Acceptable Daily Intake, is not exceeded.

Arginine starvation has the potential to selectively treat both primary tumor and (micro) metastatic tissue with very low side effects. Arginine deiminase (ADI; EC 3.5.3.6), an arginine-degrading enzyme, has been studied as a potential anti-tumor drug for the treatment of arginine-auxotrophic tumors. Though ADI-PEG20 (pegylated ADI by PEG 20,000) already passed the phase I/II clinical trials [1], it is just used as adjuvant therapy because of its low efficiency and less targeting. Then, this paper discussed the efficiency of arginine starvation mediated by ADI expressed in cytoplasm for liver cancers. In order to guarantee the tumor targeting, human telomerase reverse transcriptase (hTERT) promoter was used to drive the expression of ADI in vivo. To access the anti-tumor efficiency of ADI, p53 gene was used as the positive control. Thus, ADI displayed obvious cytotoxicity to BEL7402 and HUH7 cell lines in cytoplasm. The apoptosis rates rose from 15% to nearly 60% after changing the expression vectors from pcDNA4 plasmid to adenovirus. Compared with p53-adenovirus, ADI-adenovirus showed the higher oncolytic activity in the intratumoral injection model of mice. Tumor disappeared after the treatment of ADI-adenovirus for two weeks, and the mice pulled through all. Therefore, ADI is an ideal anti-tumor gene for caner targeting therapy with the help of hTERT promoter.

The classification of grades inside a material family should be based on the properties required by design procedures. This paper proposes a reclassification of spheroidal graphite ferritic pearlitic and ausferritic (ADI) ductile cast irons grades based on yield strength (YS), strength ratio (SR) UTS/YS and elongation at fracture (EF). In fact, these parameters are fundamental for the static assessment according to the procedures FKM Guideline and BS 7910:2005. Static assessment at room temperature, involving plastic deformation and depending on the wall thickness and stress state triaxiality, is here proposed as the most significant for the material classification. All other properties (e.g., fatigue under cyclic loads, high strain rates and temperature effect, etc.) should be reported with reference to the classification mentioned above. SR and EF control the plastic deformation at the notch tip, where maximum calculated elastic stress is redistributed. Minimum YS is usually assumed as the basic parameter for static and cyclic loading design. Because of the inverse relationship that exists between strength and ductility, Brinell hardness control and material quality index should be adopted as Material Quality Control tools, preventing from a too low EF. Fracture Toughness and its ratio with YS must be considered for preventing brittle fracture due to the presence of flaws. Fracture toughness definitions and available data are not sufficiently consistent for a correct comparison between different material grades. A surrogate Charpy energy measurement is indicated for an indirect estimate of toughness.

Submitted by Maria Fernanda Leite (leitem@stj.jus.br) on 2020-06-04T03:17:21Z No. of bitstreams: 2 caso_vaquejada_adi_leal.pdf: 187462 bytes, checksum: 31a4e6a4d28393e38a27b3a53003d7b1 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Approved for entry into archive by betanial@stj.jus.br (betanial@stj.jus.br) on 2020-06-09T23:50:13Z (GMT) No. of bitstreams: 2 caso_vaquejada_adi_leal.pdf: 187462 bytes, checksum: 31a4e6a4d28393e38a27b3a53003d7b1 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Made available in DSpace on 2020-06-09T23:50:13Z (GMT). No. of bitstreams: 2 caso_vaquejada_adi_leal.pdf: 187462 bytes, checksum: 31a4e6a4d28393e38a27b3a53003d7b1 (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Previous issue date: 2020

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Submitted by rsmoira@stj.jus.br (rsmoira@stj.jus.br) on 2020-05-12T00:26:20Z No. of bitstreams: 2 efectos_resoluciones_constitucionales_rabanal.pdf: 620071 bytes, checksum: f606fea9b289b9d0242dc18bcf2fdc6f (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Approved for entry into archive by betanial@stj.jus.br (betanial@stj.jus.br) on 2020-05-12T21:01:11Z (GMT) No. of bitstreams: 2 efectos_resoluciones_constitucionales_rabanal.pdf: 620071 bytes, checksum: f606fea9b289b9d0242dc18bcf2fdc6f (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Made available in DSpace on 2020-05-12T21:01:11Z (GMT). No. of bitstreams: 2 efectos_resoluciones_constitucionales_rabanal.pdf: 620071 bytes, checksum: f606fea9b289b9d0242dc18bcf2fdc6f (MD5) license.txt: 1239 bytes, checksum: c9b4c351324448672315a00808efb725 (MD5) Previous issue date: 2020 Analisa a localização do precedente na lei peruana, seu progresso na doutrina, as diferenças com outras figuras, como as sessões plenárias jurisdicionais, entre outros. Aborda o objetivo e as vantagens de aplicar o precedente no escopo constitucional.