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2. Quality of life in Dutch women with lichen sclerosus

Author

Lansdorp, CA, Hondel, Karen, Korfage, Ida, van Gestel, MJ, van der Meijden, WI, Epidemiology, Public Health, and Dermatology

Abstract

Background Lichen sclerosus (LS) is a chronic inflammatory skin disease. Earlier studies have shown an impaired health-related quality of life (HRQoL), but more extensive research including generic questionnaires has not been reported. Objectives To investigate, in a cross-sectional study, the HRQoL of a sample of Dutch women with LS; to compare the resulting HRQoL data with that available from other skin diseases and the general Dutch population; to explore factors that may influence the HRQoL. Methods Female members of the Dutch LS Foundation and Support Group filled out three questionnaires electronically: the Skindex-29, the SF-12 and the EQ-5D visual analogue scale (VAS). We distinguished Skindex-29 scores into groups with 'little' (score 0-24), 'mild' (25-31), 'moderate' (32-43) and 'severe' (44-100) impact on HRQoL. We compared differences using the Mann-Whitney U-test and the Kruskal-Wallis test, and correlations using Spearman's rank correlation coefficient. Results A total of 262 women with LS were included. The average diagnostic delay was 4.9 (SD 7.1) years. Patients had a mean total Skindex-29 score of 38.4 (0-100, SD 17.2). Domain scores for symptoms, emotions and functioning were 46.8 (SD 19.0), 38.2 (SD 20.2) and 33.6 (SD 19.3), respectively. The SF-12 showed average PCS-12 (physical component) and MCS-12 (mental component) scores of 47.7 and 48.5, respectively. For the Dutch population these scores were 49.3 and 52.3. The mean EQ-5D VAS scor Conclusions There is a considerable delay in diagnosis for female Dutch patients with LS. The Skindex-29 domain scores showed a moderately impaired HRQoL. Women with LS reported a lower generic HRQoL than the average female Dutch population.

Published
2013

8. Anuscarcinoom bij een HIV-positieve homoseksuele man

Author

Snoek, Eric, Ende, Marchina, Schouten, Willem Rudolf, Hollander, Jan, van der Meijden, WI, Dermatology, Internal Medicine, Surgery, and Pathology

Subjects
SDG 3 - Good Health and Well-being
Published
2006

28. Impetigo herpetiformis

Author

Couwenberg, SM, van Hussen-Brok, BAM, Waard-van der Spek, FB, van der Meijden, WI, and Dermatology

Published
2002

41. Gonorroe anno 1999

Author

Koek, DJD, van der Meijden, WI, General Practice, and Dermatology

Published
1999

44. De ziekte van Behçet

Author

Hoopen - Neumann, H, van der Meijden, WI, van Hagen, P.M., Dermatology, and Immunology

Published
1999

49. Vulvaire jeuk

Author

Dewilde, D, van der Meijden, WI, van Damme, J., Essed, G.G.M., and Dermatology

Published
1999

50. Herpes genitalis

Author

Roest, RW, van der Meijden, WI, and Dermatology

Published
1999

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