500 results on '"Oral Administration"'
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2. The pharmacokinetics of hexachlorobenzene in male beagles. Distribution, excretion, and pharmacokinetic model
3. In vitro assessment of zinc binding to protein foods as a potential index of zinc bioavailability. Comparison of in vitro and in vivo data
4. Effect of peroral administration of sotalol on the hemodynamics of the baboon
5. Metabolism of T-2 toxin in rats: Effects of dose, route, and time
6. Metabolic fate of cinmethylin in goat
7. Metabolism of 4-chlorobenzotrichloride in rats
8. Transmission of (/sup 14/C)deoxynivalenol to eggs following oral administration to laying hens
9. Development of Chiral LC-MS Methods for small Molecules and Their Applications in the Analysis of Enantiomeric Composition and Pharmacokinetic Studies
10. Gut satiety hormones cholecystokinin and glucagon-like Peptide-1{sub 7-36} amide mediate anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol
11. High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway
12. Antibiotics-induced gut microbiota dysbiosis promotes tumor initiation via affecting APC-Th1 development in mice
13. The anti-hepatocellular carcinoma cell activity by a novel mTOR kinase inhibitor CZ415
14. Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat
15. Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics
16. GSK621 activates AMPK signaling to inhibit LPS-induced TNFα production
17. AT13148, a first-in-class multi-AGC kinase inhibitor, potently inhibits gastric cancer cells both in vitro and in vivo
18. The small-molecule IAP antagonist AT406 inhibits pancreatic cancer cells in vitro and in vivo
19. TW-01, a piperazinedione-derived compound, inhibits Ras-mediated cell proliferation and angioplasty-induced vascular restenosis
20. Pre-clinical assessment of A-674563 as an anti-melanoma agent
21. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways
22. Preclinical evaluation of WYE-687, a mTOR kinase inhibitor, as a potential anti-acute myeloid leukemia agent
23. Anti-fibrotic effects of a novel small compound on the regulation of cytokine production in a mouse model of colorectal fibrosis
24. Non-absorbable mesoporous silica for the development of protein sequestration therapies
25. Catalpol ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by suppressing the JNK and NF-κB pathways
26. The anti-esophageal cancer cell activity by a novel tyrosine/phosphoinositide kinase inhibitor PP121
27. Inhibitory effect of 1,2,4,5-tetramethoxybenzene on mast cell-mediated allergic inflammation through suppression of IκB kinase complex
28. In vivo cardiac glucose metabolism in the high-fat fed mouse: Comparison of euglycemic–hyperinsulinemic clamp derived measures of glucose uptake with a dynamic metabolomic flux profiling approach
29. The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production
30. Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK
31. In vivo and in vitro toxicological effects of titanium dioxide nanoparticles on small intestine
32. Application of dynamic metabolomics to examine in vivo skeletal muscle glucose metabolism in the chronically high-fat fed mouse
33. Rhamnazin, a novel inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy
34. A novel chalcone derivative attenuates the diabetes-induced renal injury via inhibition of high glucose-mediated inflammatory response and macrophage infiltration
35. Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues
36. Characterization of acute biliary hyperplasia in Fisher 344 Rats administered the Indole-3-Carbinol Analog, NSC-743380
37. Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis
38. Novel distribution of calreticulin to cardiomyocyte mitochondria and its increase in a rat model of dilated cardiomyopathy
39. Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment
40. Aliskiren toxicity in juvenile rats is determined by ontogenic regulation of intestinal P-glycoprotein expression
41. Inhibitory effect of putranjivain A on allergic inflammation through suppression of mast cell activation
42. A novel synthetic analog of militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells
43. Curine inhibits eosinophil activation and airway hyper-responsiveness in a mouse model of allergic asthma
44. Endocrine disruptors found in food contaminants enhance allergic sensitization through an oxidative stress that promotes the development of allergic airway inflammation
45. A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia
46. SL-01, an oral derivative of gemcitabine, inhibited human breast cancer growth through induction of apoptosis
47. Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans
48. Poly(lactic-co-glycolic) acid loaded nano-insulin has greater potentials of combating arsenic induced hyperglycemia in mice: Some novel findings
49. Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice
50. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats
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