59 results on '"Dambrova, Maija"'
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2. Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models
3. Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats
4. Sigma-1 receptor and seizures
5. Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
6. Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage
7. Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures
8. Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury
9. Inhibition of sigma-1 receptors substantially modulates GABA and glutamate transport in presynaptic nerve terminals
10. Pharmacological approaches to tackle NCLs
11. Effects of the N-methyl-d-aspartate receptor antagonist, MK-801, on spatial memory and influence of the route of administration
12. Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury
13. High-resolution respirometry for measurement of fatty acid β-oxidation in brain mitochondria. A comparative study and application in ischemia and aging
14. S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity
15. The activity of selective sigma-1 receptor ligands in seizure models in vivo
16. Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity
17. Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance
18. The neuroprotective effects of R-phenibut after focal cerebral ischemia
19. R-phenibut binds to the α2–δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects
20. Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis
21. Structure and Function of CutC Choline Lyase from Human Microbiota Bacterium Klebsiella pneumoniae
22. Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation
23. Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size
24. Mildronate, the inhibitor of l-carnitine transport, induces brain mitochondrial uncoupling and protects against anoxia-reoxygenation
25. A cross-sectional survey of urinary iodine status in Latvia
26. The heart is better protected against myocardial infarction in the fed state compared to the fasted state
27. Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor
28. Association of reduced glyoxalase 1 activity and painful peripheral diabetic neuropathy in type 1 and 2 diabetes mellitus patients
29. Troubleshooting digital macro photography for image acquisition and the analysis of biological samples
30. Glyoxalase 1 and glyoxalase 2 activities in blood and neuronal tissue samples from experimental animal models of obesity and type 2 diabetes mellitus
31. The sensorimotor and cognitive deficits in rats following 90- and 120-min transient occlusion of the middle cerebral artery
32. High l-carnitine concentrations do not prevent late diabetic complications in type 1 and 2 diabetic patients
33. Mildronate treatment improves functional recovery following middle cerebral artery occlusion in rats
34. Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats
35. Anti-diabetic effects of mildronate alone or in combination with metformin in obese Zucker rats
36. The anti-inflammatory and antinociceptive effects of NF-κB inhibitory guanidine derivative ME10092
37. Metabolomic studies of experimental diabetic urine samples by 1H NMR spectroscopy and LC/MS method
38. Effect of inhibiting carnitine biosynthesis on male rat sexual performance
39. Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart
40. Comparative pharmacological activity of optical isomers of phenibut
41. The MC 3 receptor binding affinity of melanocortins correlates with the nitric oxide production inhibition in mice brain inflammation model
42. The differential influences of melanocortins on nociception in the formalin and tail flick tests
43. Data on cardiac and vascular functionality in ex vivo and in vivo models following acute administration of trimethylamine N-oxide
44. beta-MSH inhibits brain inflammation via MC 3/ 4 receptors and impaired NF-κB signaling
45. β- and γ-melanocortins inhibit lipopolysaccharide induced nitric oxide production in mice brain
46. Mildronate: Cardioprotective Action through Carnitine-Lowering Effect
47. The novel guanidine ME10092 protects the heart during ischemia–reperfusion
48. N-Hydroxyguanidine Compound 1-(3,4-Dimethoxy- 2-chlorobenzylideneamino)-3-hydroxyguanidine Inhibits the Xanthine Oxidase Mediated Generation of Superoxide Radical
49. Data on medicinal plants in the records of Latvian folk medicine from the 19th century
50. Data on analysis of MK-801 bioavailability in mouse plasma and brain tissue by ultra-performance liquid chromatography-tandem mass spectrometry
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