58 results on '"Sim, Robert"'
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2. Intrinsic chemical reactivity of activated human complement component C3: A historical glimpse into research during 1979–1980 on the covalent binding properties of C3, C4 and alpha-2 macroglobulin
3. Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients
4. Recombinant chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) protects against LPS-induced lung injury in mice
5. Complement factor H interferes with Mycobacterium bovis BCG entry into macrophages and modulates the pro-inflammatory cytokine response
6. 52 Human factor H and properdin modulate SARS-CoV-2 infection in a complement-independent manner
7. Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes
8. Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages
9. Human complement Factor H modulates C1q-mediated phagocytosis of apoptotic cells
10. Factor H as a regulator of the classical pathway activation
11. Chemical labelling of active serum thioester proteins for quantification
12. Understanding the laminated layer of larval Echinococcus II: immunology
13. Complement in health and disease
14. Complement activation by carbon nanotubes
15. The human lung surfactant proteins A (SP-A) and D (SP-D) interact with apoptotic target cells by different binding mechanisms
16. Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi
17. Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions
18. Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1
19. Multiple routes of complement activation by Mycobacterium bovis BCG
20. The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen
21. Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen)
22. Cryoglobulins as indicators of upregulated immune response in schizophrenia
23. C1q binding and complement activation by prions and amyloids
24. C1q and its growing family
25. Binding of pulmonary surfactant proteins to carbon nanotubes; potential for damage to lung immune defense mechanisms
26. Interactions between Neisseria meningitidis and the complement system
27. Prion protein activates and fixes complement directly via the classical pathway: Implications for the mechanism of scrapie agent propagation in lymphoid tissue
28. Molecular organization of human Ficolin-2
29. His-384 Allotypic Variant of Factor H Associated with Age-related Macular Degeneration Has Different Heparin Binding Properties from the Non-disease-associated Form
30. C1q and tumor necrosis factor superfamily: modularity and versatility
31. The Biological Functions of MBL-Associated Serine Proteases (MASPs)
32. A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2
33. Heterogeneity of MBL–MASP complexes
34. Reactivity of MASP-1 and MASP-2 with serum protease inhibitors
35. Complement activation by Mycobacterium bovis BCG
36. SP-A
37. SP-D
38. Multiple-routes of complement activation by Mycobacterium bovis BCG
39. The factor H variant associated with age-related macular degeneration (H384) and the non-disease associated form bind differentially to C-reactive protein, fibromodulin, DNA and necrotic cells
40. Evidence for a monomer-dimer equilibrium in native human Factor H
41. Interactions between factor H and Neisseria meningitidis
42. Complement interaction with Mycobacterium bovis BCG
43. Investigation of L-ficolin binding specificity
44. Ficolin-MASPs in complement and coagulation pathways
45. Investigation into the glycosaminoglycan-binding properties of the AMD- and non-disease associated complement factor H variants H384 and Y384 (H402Y)
46. MBL and L-ficolin components of the complement activation lectin pathway in schizophrenia
47. Towards a structural basis for complement factor H linked age-related macular degeneration
48. Crystallographic studies of sugar binding by factor H domains 6–8
49. C1QTNF5, which is mutated in late-onset retinal macular degeneration, interacts with complement factor H
50. Crystallographic studies of human complement factor I
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