53 results on '"Takashima, Akihiko"'
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2. Frontotemporal dementia with Parkinsonism linked to chromosome-17 mutations enhance tau oligomer formation
3. Assessment of Pulp Regeneration Induced by Stem Cell Therapy by Magnetic Resonance Imaging
4. Neurodegenerative Disorder FTDP-17–Related Tau Intron 10 +16C→T Mutation Increases Tau Exon 10 Splicing and Causes Tauopathy in Transgenic Mice
5. Can the entorhinal cortex help distinguish healthy aging brains from pathological aging brains?
6. Memory formation in old age requires GSK-3β
7. Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway: Role of GSK-3β in Adult Brain
8. Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain
9. Methylmercury exposure downregulates the expression of Racl and leads to neuritic degeneration and ultimately apoptosis in cerebrocortical neurons
10. Loss of M 5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice
11. Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone
12. Presenilin-1 Mutation L271V Results in Altered Exon 8 Splicing and Alzheimer's Disease with Non-cored Plaques and No Neuritic Dystrophy
13. Frequency shift feedback imaging in liquid for biological molecules
14. Intracellular Aβ is increased by okadaic acid exposure in transfected neuronal and non-neuronal cell lines
15. Formation of Filamentous Tau Aggregations in Transgenic Mice Expressing V337M Human Tau
16. Twenty-nine missense mutations linked with familial Alzheimer's disease alter the processing of presenilin 1
17. NOVEL INSIGHTS OF TAU RNA-PROTEIN BIOLOGY IN THE PRECIPITATING ROLE OF CHRONIC STRESS ON ALZHEIMER’S DISEASE BRAIN PATHOLOGY
18. ISO-α-ACIDS, BITTER COMPONENTS IN BEER, IMPROVE HIPPOCAMPUS-DEPENDENT MEMORY VIA DOPAMINE RELEASE
19. ISO-α-ACIDS, BITTER COMPONENTS OF BEER, PREVENT CEREBRAL INFLAMMATION AND COGNITIVE DECLINE IN A MOUSE MODEL OF ALZHEIMER’S DISEASE
20. Microtubule destruction induces tau liberation and its subsequent phosphorylation
21. Mechanism of neurodegeneration through tau and therapy for Alzheimer's disease
22. I2020T LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3beta signaling pathway
23. GRANULAR TAU OLIGOMER AS TOXIC TAU AGGREGATION FORM IN AD
24. Stress triggers tau aggregation through dysregulation of the chaperone-mediated degradation machinery and promotion of apoptosis
25. Phenolic compounds prevent beta-amyloid-protein oligomerization and synaptic dysfunction by site-specific binding
26. Granular tau oligomer: Intermediate of tau fibril is involved in neuronal loss
27. Vitamin A has anti-oligomerization effects on Aβ in vitro
28. Synaptic long-term depression as a key to understanding the amyloid-tau connection
29. Spatiotemporally specific alterations of microtubule-associated proteins and memory in alloxan-treated tau transgenic mice
30. The mechanism for tau aggregation and its relation to neuronal dysfunction
31. Targetting tau aggregation as therapy of dementia
32. Distinct tau aggregation form involved in synapse loss and neuron loss
33. Examining the link between synaptosomal accumulation of tau protein and cognitive dysfunction
34. P4-221: GABA-linked acceleration of aging-associated memory decline in APP/PS1 transgenic mouse and its pharmacological treatment by picrotoxin
35. P2-161: Behavioral abnormality in female mice expressing wild-type human tau without neurofibrillary tangles
36. P2-128: Linkage between spatial memory disturbance and tau protein in JNPL3 male mice
37. O2-05-06: Gender-dependent neurodegenerative potential of chronic stress in P301l Tau transgenic mice
38. S2-01-06: Granular Tau oligomer: An early diagnostic marker for Alzheimer's disease
39. P3-314: Molecular chaperone related tau protein metabolism in human brain
40. S3-03-05: Animal models
41. P2-089 Early behavioral abnormalities in a mouse model of FTDP-17
42. P4-369 Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease
43. P3-249 Possible functions of human 3 repeat tau isoform in transgenic mice with regionally specific expression
44. P1-189 Mechanism of AB induced cytotoxicity: toxic AB aggregate associates with cell membrane via positive charge clusters
45. P1-176 Age-related changes of Alzheimer's disease-associated protein in cynomolgus monkey brains
46. S4-01-01 Mechanism of neurofibrillary tangle formation: tau accumulation and fibril formation
47. O3-05-02 FAD-linked presenilin-1 mutations affect the N-cadherin/CBP signaling pathway via a loss-of-function mechanism
48. O2-05-07 Insulin dysfunction induces abnormal tau hyperphosphorylation through two distinct mechanisms: implications for diabetes and Alzheimer's disease
49. Possible involvement of GSK-3βin regulation of aβmetabolism in the transfected cell lines
50. Regulation of amyloidogenesis and βAPP trafficking
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