18 results on '"Machado-Neto, João Agostinho"'
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2. Autophagy and inflammasome activation are associated with poor response to FLT3 inhibitors in patients with FLT3-ITD acute myeloid leukemia
3. NSC305787, a pharmacological ezrin inhibitor, exhibits antineoplastic activity in pancreatic cancer cells
4. Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model
5. STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells
6. NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells
7. The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy
8. Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia
9. AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis
10. NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia
11. Reversine exerts cytotoxic effects through multiple cell death mechanisms in acute lymphoblastic leukemia
12. Stathmin 1 is highly expressed and associated with survival outcome in malignant adrenocortical tumours
13. Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells
14. NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2V617F-positive myeloproliferative neoplasm cells
15. Reversine exhibits antineoplastic activity in JAK2V617F-positive myeloproliferative neoplasms
16. Increased levels of cyclin D1 negatively impacts on acute lymphoblastic leukemia overall survival
17. Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms
18. PIPKIIα is widely expressed in hematopoietic-derived cells and may play a role in the expression of alpha- and gamma-globins in K562 cells
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