34 results on '"Silke, John"'
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2. RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation
3. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency
4. Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
5. Blocking cell death limits lung damage and inflammation from influenza
6. RIPK1 and necroptosis role in premature ageing
7. A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
8. The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family
9. Apoptotic cell death in disease—Current understanding of the NCCD 2023
10. MLKL deficiency protects against low-grade, sterile inflammation in aged mice
11. High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell death
12. Deletion of Gpatch2 does not alter Tnf expression in mice
13. OXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling
14. Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
15. Dual roles for LUBAC signaling in thymic epithelial cell development and survival
16. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL
17. Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1−/− mice
18. Targeting triple-negative breast cancers with the Smac-mimetic birinapant
19. Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease
20. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
21. The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis
22. The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
23. MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
24. A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
25. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
26. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
27. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
28. Addendum: A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
29. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
30. LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
31. The intersection of cell death and inflammasome activation
32. The diverse role of RIP kinases in necroptosis and inflammation
33. Is BID required for NOD signalling?
34. Evidence for erosion of mouse CpG islands during mammalian evolution
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