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Background: Persistent genital arousal disorder (PGAD) is a rare condition characterized by unwanted and distressing symptoms of arousal and dysesthesia. The aim of this scoping review was to map the current state of PGAD management, identify gaps in the literature, and understand patient perspectives. Methods: We completed a scoping review following guidelines from the Joanna Briggs Institute and the Preferred Reporting Items for Systematic Reviews and Meta Analyses Scoping Reviews extension. A systematic literature search for articles pertaining to PGAD/genito-pelvic dysesthesia (GPD) was conducted in August 2023 via Medline, Embase, Scopus, and Web of Science. The search returns were deduplicated and the remaining titles and abstracts were screened for inclusion. General publication characteristics and treatment data were extracted from the included publications via a pilot-tested Google form. All screening and extraction were completed in a masked, duplicate fashion. Results: Findings from our scoping review revealed a scarcity of systematic research, limited evidence-based data, and the importance of addressing both physical and psychiatric concerns. Our sample included 46 publications from an initial pool of 636 returns. Case studies were the most common study design. Thirty-three studies examined medication, either alone or as part of a treatment regimen. Selective serotonin reuptake inhibitors were the most used medication, followed by pramipexole and carbamazepine. Seven studies used a surgical or procedural intervention. Treatment with pelvic floor Botox was the most common procedure. Patient perspectives in the included case studies highlighted themes of shame, suicidal ideation, social isolation, decreased sleep, and overall decline in quality of life. Conclusion: The findings from our study emphasize patients' distressing and psychiatric symptoms, indicating a need to improve treatment regimens, using both evidence-based research outcomes and patient-reported outcomes. Management for PGAD/GPD lacks a standardized framework, indicating a need for further research and the development of clinical practice guidelines to improve patient care. [ABSTRACT FROM AUTHOR]

BACKGROUND: We identified peripherally limited patients using cardiopulmonary exercise testing and measured skeletal muscle oxygen transport and utilization during invasive single leg exercise testing to identify the mechanisms of the peripheral limitation. METHODS: Forty-five patients with heart failure with preserved ejection fraction (70±7 years, 27 females) completed seated upright cardiopulmonary exercise testing and were defined as having a (1) peripheral limitation to exercise if cardiac output/oxygen consumption (VO2) was elevated (=6) or 5 to 6 with a stroke volume reserve >50% (n=31) or (2) a central limitation to exercise if cardiac output/VO2 slope was =5 or 5 to 6 with stroke volume reserve <50% (n=14). Single leg knee extension exercise was used to quantify peak leg blood flow (Doppler ultrasound), arterial-to-venous oxygen content difference (femoral venous catheter), leg VO2, and muscle oxygen diffusive conductance. In a subset of participants (n=36), phosphocreatine recovery time was measured by magnetic resonance spectroscopy to determine skeletal muscle oxidative capacity. RESULTS: Peak VO2 during cardiopulmonary exercise testing was not different between groups (central: 13.9±5.7 versus peripheral: 12.0±3.1 mL/min per kg; P=0.135); however, the peripheral group had a lower peak arterial-to-venous oxygen content difference (central: 13.5±2.0 versus peripheral: 11.1±1.6 mLO2/dL blood; P<0.001). During single leg knee extension, there was no difference in peak leg VO2 (P=0.306), but the peripherally limited group had greater blood flow/VO2 ratio (P=0.024), lower arterial-to-venous oxygen content difference (central: 12.3±2.5 versus peripheral: 10.3±2.2 mLO2/dL blood; P=0.013), and lower muscle oxygen diffusive conductance (P=0.021). A difference in magnetic resonance spectroscopy-derived phosphocreatine recovery time was not detected (P=0.199). CONCLUSIONS: Peripherally limited patients with heart failure with preserved ejection fraction identified by cardiopulmonary exercise testing have impairments in oxygen transport and utilization at the level of the skeletal muscle quantified by invasive knee extension exercise testing, which includes an increased blood flow/VO2 ratio and poor muscle diffusive capacity. [ABSTRACT FROM AUTHOR]

To determine factors influencing low-field MRI lung opacity severity 6–24 months after acute Covid-19 pneumonia. 104 post-acute Covid-19 patients with 167 MRI exams were included. 32 patients had more than one exam, and 63 exams were serial exams. Pulmonary findings were graded on a scale of 0–4 by quadrant, total score ranging from 0 (no opacity) to 16 (opacity > 75%), and score >8 considered moderate and >12 severe opacity. Kruskal-Wallis, Mann-Whitney, and Spearman rank correlation was used to assess the association of clinical and demographic factors with MR opacity severity at time intervals from acute infection. Random coefficients regression was used to assess whether opacity score changed over time. Severity of initial illness was associated with increased MR opacity score at timeframes up to 24 months (p <.05). Among the 167 exams, moderate to severe MR opacities (total opacity score >8) were identified in 33% of exams beyond 6 months: 37% at 6 - <12 months (n = 23/63); 31% at 12- < 18 months (n = 13/42); 25% at 18- < 24 months (n = 6/24); and 50% at > 24 months (n = 3/6). No significant change in total opacity score over time was identified by random coefficients regression. Among the 32 patients with serial exams, 11 demonstrated no change in opacity score from initial to final exam, 10 decrease in score (mean 2.3, stdev 1.25, range 1–4), and 11 increase in score (average 2.8, stdev 1.48, range 1–7). Initial Covid-19 disease severity was associated with increased MRI total opacity score at time intervals up to 24 months, and moderate to severe opacities were commonly identified by low-field MRI beyond 6 months from acute illness. • Initial Covid-19 disease severity was associated with increased MRI total opacity score at timeframes up to 24 months. • No significant decrease in opacity score over time was identified, with approximately even distribution of patients with unchanged, decreased, and increased total opacity scores from initial to final exam. • Moderate to severe opacities were observed in 33% of low-field MRI exams beyond 6 months from acute Covid-19 pneumonia. [ABSTRACT FROM AUTHOR]

Purpose: Civic education in the US has historically centered the nation-state. This is often disempowering for marginalized students who exist outside the national narrative and political sphere. Design/methodology/approach: This year-long ethnographic study considers what counts as civic education in the US Virgin Islands, a territory of the US. This paper draws on critical theory and critical pedagogy to understand ways teachers in a politically and culturally marginalized space can reimagine civic education. Classroom observations, interviews and curriculum content analysis are used as data. Findings: The findings suggest that teachers centered the local by surfacing the unjust political relationship between the US and its territories and incorporating local history, civic engagement, resistance and culture to politically empower their students. Originality/value: This research will contribute a deeper understanding of the possibilities for civic education to be empowering for those who are marginalized and often excluded from the national political arena. [ABSTRACT FROM AUTHOR]

The Thrifty Food Plan emerged from the Economy Food Plan in 1975 as a mathematical program that represented a nutritious diet for low-income Americans. Calculated last in 2021 by the US Department of Agriculture's Center for Nutrition Policy and Promotion, the Thrifty Food Plan determines the maximum amount of food assistance for households participating in the Supplemental Nutrition Assistance Program. Drawing on national archives, interviews, congressional discourse analysis, literature review, and mathematical modeling, this paper traces a genealogy of the Thrifty Food Plan from 1975 to the present along six themes. This genealogy tells a story of changing consumption patterns, dietary standards, and the ways in which the USDA defines food, people, and the basic food needs of the poorest Americans. This paper highlights avenues for further research into the various aspects of the Thrifty Food Plan that can elucidate the historical framing of hunger and poverty in the United States. [ABSTRACT FROM AUTHOR]

To evaluate the efficacy of a multimodal intervention in reducing CT pulmonary angiography (CTPA) overutilization in the evaluation of suspected pulmonary embolism in the emergency department (ED). Previous mixed-methods analysis of barriers to guideline-concordant CTPA ordering results was used to develop a provider-focused behavioral intervention consisting of a clinical decision support tool and an audit and feedback system at a multisite, tertiary academic network. The primary outcome (guideline concordance) and secondary outcomes (yield and CTPA and D-dimer order rates) were compared using a pre- and postintervention design. ED encounters for adult patients from July 5, 2017, to January 3, 2019, were included. Fisher's exact tests and statistical process control charts were used to compare the pre- and postintervention groups for each outcome. Of the 201,912 ED patient visits evaluated, 3,587 included CTPA. Guideline concordance increased significantly after the intervention, from 66.9% to 77.5% (P <.001). CTPA order rate and D-dimer order rate also increased significantly, from 17.1 to 18.4 per 1,000 patients (P =.035) and 30.6 to 37.3 per 1,000 patients (P <.001), respectively. Percent yield showed no significant change (12.3% pre- versus 10.8% postintervention; P =.173). Statistical process control analysis showed sustained special-cause variation in the postintervention period for guideline concordance and D-dimer order rates, temporary special-cause variation for CTPA order rates, and no special-cause variation for percent yield. Our success in increasing guideline concordance demonstrates the efficacy of a mixed-methods, human-centered approach to behavior change. Given that neither of the secondary outcomes improved, our results may demonstrate potential limitations to the guidelines directing the ordering of CTPA studies and D-dimer ordering. [Display omitted] [ABSTRACT FROM AUTHOR]

Superficial femoral artery (SFA) stenting is a common treatment for peripheral artery disease. It is effective in the short term; however, in-stent restenosis (ISR) limits long-term success. Surveillance with duplex ultrasound (DUS) can identify patients who develop ISR leading to early reintervention, but data to support this practice is sparce. The purpose of this study was to evaluate whether surveillance and subsequent reintervention improves outcomes in patients with SFA stents. A single-center, retrospective study was performed with patients undergoing SFA stenting between 2005 and 2020 who had a follow-up with DUS. Five groups were identified based on the presence of ISR on DUS (ISR vs no ISR [NISR]), recurrence of symptoms (symptomatic [SX] vs asymptomatic [ASX]), and if any reintervention was performed (reintervention [R] vs no reintervention [NR]): (1) ISR+SX+R; (2) ISR+SX+NR; (3) ISR+ASX+R; (4) ISR+ASX+NR; and (5) NISR+NR. The primary endpoint was amputation-free survival, and the secondary endpoint was patency. Predictors of mortality and surveillance were identified by multivariable logistic regressions and Cox multivariate regression models. Survival curves were presented as Kaplan-Meier plots using log-rank test for subgroup comparison. Two hundred fifty-seven patients were included in the analysis. The indication for intervention was claudication in 28% and chronic limb-threatening ischemia in 72%. A total of 161 patients (63%) underwent reintervention for ISR. Of patients who had restenosis on DUS, those who were symptomatic and did not undergo reintervention (ISR+SX+NR) did the worst, with 50% amputation rate. In contrast, those who were asymptomatic but did undergo reintervention (ISR+ASX+R) had the lowest amputation rate of 13%. Active smoking was a predictor of both loss of patency and amputation (1.72; 95% confidence interval [CI], 1.00-2.98; P =.050; 3.55; 95% CI, 1.53-8.25; P =.003). Post procedure dual antiplatelet therapy had a positive association with limb salvage (hazard ratio [HR], 0.23; 95% CI, 0.09-0.58; P =.001), whereas diabetes (HR, 2.61; 95% CI, 1.21-6.01; P =.019), stent occlusion (HR, 17.0; 95% CI, 5.93-63.1; P <.001), and chronic limb-threatening ischemia presentations (HR, 4.31; 95% CI, 1.86-11.7; P =.002) were negatively associated with limb salvage. Routine surveillance DUS and subsequent reintervention on ISR after SFA stenting is associated with improved patency and amputation-free survival. Surveillance DUS should be routine for patients after stenting, with reintervention strongly considered if ISR is identified for both symptomatic and asymptomatic. [ABSTRACT FROM AUTHOR]

The current study further explored the relationship between nontraditional students and academic entitlement. Previous research has established that the presence of more nontraditional factors predicts lower levels of reported academic entitlement. The mechanisms responsible for this connection have not been explored though. The current study examined the impact of locus of control on the relationship between nontraditional factors and academic entitlement. Participants (N = 332) were asked to report their status on seven nontraditional factors and then completed measures exploring locus of control, academic entitlement, work engagement, and academic motivation. Analyses revealed that nontraditional factors predicted lower levels of external locus of control and external locus of control was negatively correlated with academic entitlement. Evidence for partial mediation was found for this relationship. The impact of these findings on nontraditional students, retention, and academic interventions is discussed. [ABSTRACT FROM AUTHOR]

Copyright of Atmosphere -- Ocean (Taylor & Francis Ltd) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Quality assurance (QA) of predoctoral dental student laboratory work is an essential part of the learning process that involves evaluating the student's ability, providing constructive feedback, helping develop the students' ability to self‐assess, and promoting collegiality and communication among students, faculty, and laboratories. Faculty calibration, while often difficult to coordinate, is also necessary to providing consistent student feedback. Aim: The purpose of this study was to evaluate whether periodic calibration exercises with the fourth‐year dental students and faculty impacted the number of student cases rejected during Quality Assurance evaluation of fixed prosthodontic cases submitted to The Dental College of Georgia laboratory tracking. Conclusion: Findings from this study provided evidence that ongoing calibration did result in a reduced number of incoming QA rejections in all periods reviewed except for one in which there was significant turnover among department faculty affecting QA calibration for that time period. [ABSTRACT FROM AUTHOR]

Schools in the United States have often been tasked with cultivating a political identity that is connected to the nationstate. In the civics classroom, this often means teaching a nation-state centered civic education, which can create a sense of disjuncture for some students. This year-long ethnographic study explores disenfranchised students living in the Virgin Islands' political identities and interests and how their teachers responded to them. The findings suggest that students entered the classroom with developed and varied political interests and identities that would not necessarily be recognized in a traditional nation-state centered civics class. Teachers responded by providing a culturally sustaining and humanizing civic education that honored their students' diverse political and cultural identities and interests. [ABSTRACT FROM AUTHOR]

This study examined whether emotion regulation difficulties and resilience in college students moderated changes in mental health over the course of the COVID-19 pandemic. Participants (N = 321) completed surveys assessing mental health, in addition to levels of emotion dysregulation, and resilience during the pandemic, then utilized an anchoring prompt to recall mental health experiences before the pandemic. Correlations revealed participants with higher levels of emotion dysregulation also reported lower levels of resilience. Analyses using the SPSS Macro MEMORE (Montoya, 2019) revealed participants with higher levels of emotion regulation difficulties had greater increases in depression and insomnia, and greater decreases in well-being over the course of the COVID-19 pandemic, while participants with lower levels of resilience had greater increases in depression, anxiety, and insomnia over the course of the pandemic. These results highlight the importance of additional support services and mental health training at universities to meet college students' immediate and long-term emotional needs stemming from the pandemic. [ABSTRACT FROM AUTHOR]

Despite the established value of diversity, equity, and inclusion as critical components to achieving academic excellence, building diversity within nursing education remains a challenge. Institutional gatekeeping, overt racism, and implicit biases are barriers that perpetuate a low percentage of nursing faculty of color. From pre-search strategic prioritization to submission of the search committee report, a multi-prong, just, transparent, systematic, and strategic approach to hiring is needed to advance opportunities for hiring a diverse faculty. This article provides nursing administration leaders, search committee members, and faculty engaged in hiring practices with a stepwise review of specific strategies. Evidence and tools to mitigate bias, attract excellent and diverse applicant pools, conduct fair evaluations, and support ongoing reflection and improvement of hiring practices are described. An overview of types of implicit bias in hiring practices, descriptive evaluation rubrics, and self-reflection questions are included. • Current hiring practices in nursing education do not promote a diverse faculty • Faculty of color deserve a fair opportunity to be hired • A diverse faculty is an essential component to achieve excellent learning communities, scholarship, and health care outcomes • Faculty must disrupt the status quo and engage in a just, transparent, multi-prong, systematic, and strategic approach to diversify their faculty [ABSTRACT FROM AUTHOR]

Introduction: Effective analgesia after total hip arthroplasty must minimize pain and optimize early ambulation. Lumbar plexus blocks (LPBs) provide analgesia but may cause motor weakness. Quadratus lumborum blocks (QLBs) may provide analgesia with preserved motor strength.Methods: This trial randomized subjects scheduled for elective hip arthroplasty to receive an LPB or lateral QLB for postoperative analgesia. The primary outcome was opioid consumption at 12-hour postoperative. Non-inferiority of lateral QLBs compared with LPBs was conducted using a one-sided two-sample t-test. Secondary outcomes included pain scores, cumulative opioid consumption, quadriceps strength, time to ambulation, and distance ambulated. Differences in pain scores and opioid consumption over time between groups were evaluated using a linear mixed model.Results: The trial consented and randomized 111 subjects and 103 completed the study: LPB (n=50) and lateral QLB (n=53). Mean (95% CI) cumulative opioid consumption (mg) at 12-hour postoperative was not found to be non-inferior in the lateral QLB (15.9 (12.7 to 19.2)) vs the LPB (12.7 (10.2 to 15.1)) group (p=0.625). Pain scores in postoperative anesthetic care unit (PACU) and 24-hour postoperative did not differ. The maximum distance ambulated did not differ, but lateral QLB patients were 2.4 times more likely to ambulate in the first 12 hours (p=0.024) and had significantly greater quadriceps strength in PACU (p<0.001).Discussion: Although we were unable to demonstrate non-inferiority for opioid consumption at 12-hour postoperative, strength and mobilization were improved in lateral QLB subjects.Trial Registration Number: NCT04402437. [ABSTRACT FROM AUTHOR]

Copyright of Canadian Journal of Education / Revue Canadienne de l'Éducation is the property of Canadian Society for the Study of Education and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Maritime drug trafficking poses a serious threat to the security and societal well-being of the United States. As one of the largest consumers of foreign-cultivated illicit drugs, the United States serves as a lucrative market for international drug trafficking organizations. Exploiting this insatiable demand, drug traffickers often use maritime routes in the Eastern Pacific Ocean, the Caribbean Sea, and the Gulf of Mexico to convey bulk quantities of drugs ultimately bound for the United States. The United States Coast Guard, which is charged with stopping drug traffickers within this six million square mile maritime zone, faces a task akin to searching for a needle in a haystack. Seeking to enhance the Coast Guard's ability to suppress drug trafficking efforts as close to their origins as possible, the Maritime Drug Law Enforcement Act (MDLEA), which criminalizes extraterritorial maritime drug trafficking. includes a farreaching provision providing for United States jurisdiction over drug trafficking vessels interdicted in the territorial seas of a foreign nation. While the MDLEA has generally withstood constitutional attack since the statute's enactment, the U.S. Court of Appeals for the Eleventh Circuit struck major blows to the constitutionality of this critical provision of the MDLEA in United States v. Bellaizac-Hurtado and United States v. Davila - Mendoza. In each case, the Eleventh Circuit held that Congress exceeded its authority under Article I, Section 8 of the U.S. Constitution in criminalizing the drug trafficking conduct of foreign persons aboard foreign vessels in foreign territorial seas. The Eleventh Circuit' s holdings seriously undermine the United States' ability to suppress maritime drug trafficking, signaling to drug traffickers that they may remain beyond the reach of the United States simply by shifting their trafficking routes to remain entirely within the territorial seas of Caribbean, Central American, and South American nations, where there is a markedly limited law enforcement presence. Contrary to the Eleventh Circuit's holdings. however, this Note argues that Congress does have the power to criminalize the drug trafficking conduct of foreign persons aboard foreign vessels in foreign territorial seas under the Define and Punish Clause, the Foreign Commerce Clause, and the Necessary and Proper Clause. The Eleventh Circuit stands alone in holding that the MDLEA is unconstitutional as applied to foreign persons aboard foreign vessels in foreign territorial seas. Other circuits should not follow the Eleventh Circuit's lead but should instead find that Article 1, Section 8 supports such an application of the MDLEA. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the impact of structured recommendations on follow-up completion for incidental lung nodules (ILNs).Methods: Patients with ILNs before and after implementation of structured Fleischner recommendations and electronic tracking were sampled randomly. The cohorts were compared for imaging follow-up. Multivariable logistic regression was used to assess appropriate follow-up and loss to follow-up, with independent variables including use of structured recommendations or tracking, age, sex, race, ethnicity, setting of the index test (inpatient, outpatient, emergency department), smoking history, and nodule features.Results: In all, 1,301 patients met final inclusion criteria, including 255 patients before and 1,046 patients after structured recommendations or tracking. Baseline differences were found in the pre- and postintervention groups, with smaller ILNs and younger age after implementing structured recommendations. Comparing pre- versus postintervention outcomes, 40.0% (100 of 250) versus 29.5% (309 of 1,046) of patients had no follow-up despite Fleischner indications for imaging (P = .002), and among the remaining patients, 56.6% (82 of 145) versus 75.0% (553 of 737) followed up on time (P < .001). Delayed follow-up was more frequent before intervention. Differences postintervention were mostly accounted for by nodules ≤8 mm in the outpatient setting (P < .001). In multivariable analysis, younger age, White race, outpatient setting, and larger nodule size showed significant association with appropriate follow-up completion (P < .015), but structured recommendations did not. Similar results applied for loss to follow-up.Discussion: Consistent use of structured reporting is likely key to mitigate selection bias when benchmarking rates of appropriate follow-up of ILN. Emergency department patients and inpatients are at high risk of missed or delayed follow-up despite structured recommendations. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the inter-observer consistency for subsolid pulmonary nodule radiomic features.Materials and Methods: Subsolid nodules were selected by reviewing radiology reports of CT examinations performed December 1, 2015 to April 1, 2016. Patients with CTs at two time points were included in this study. There were 55 patients with subsolid nodules, of whom 14 had two nodules. Of 69 subsolid nodules, 66 were persistent at the second time point, yielding 135 lesions for segmentation. Two thoracic radiologists and an imaging fellow segmented the lesions using a semi-automated volumetry algorithm (Syngo.via Vb20, Siemens). Coefficient of variation (CV) was used to assess consistency of 91 quantitative measures extracted from the subsolid nodule segmentations, including first and higher order texture features. The accuracy of segmentation was visually graded by an experienced thoracic radiologist. Influencing factors on radiomic feature consistency and segmentation accuracy were assessed using generalized estimating equation analyses and the Exact Mann-Whitney test.Results: Mean patient age was 71 (38-93 years), with 39 women and 16 men. Mean nodule volume was 1.39mL, range .03-48.2mL, for 135 nodules. Several radiomic features showed high inter-reader consistency (CV<5%), including entropy, uniformity, sphericity, and spherical disproportion. Descriptors such as surface area and energy had low consistency across inter-reader segmentations (CV>10%). Nodule percent solid component and attenuation influenced inter-reader variability of some radiomic features. The presence of contrast did not significantly affect the consistency of subsolid nodule radiomic features. Near perfect segmentation, within 5% of actual nodule size, was achieved in 68% of segmentations, and very good segmentation, within 25% of actual nodule size, in 94%. Morphologic features including nodule margin and shape (each p <0.01), and presence of air bronchograms (p = 0.004), bubble lucencies (p = 0.02) and broad pleural contact (p < 0.01) significantly affected the probability of near perfect segmentation. Stroke angle (p = 0.001) and length (p < 0.001) also significantly influenced probability of near perfect segmentation.Conclusions: The inter-observer consistency of radiomic features for subsolid pulmonary nodules varies, with high consistency for several features, including sphericity, spherical disproportion, and first and higher order entropy, and normalized non-uniformity. Nodule morphology influences the consistency of subsolid nodule radiomic features, and the accuracy of subsolid nodule segmentation. [ABSTRACT FROM AUTHOR]

With stress documented beyond inherent levels in our initial research with Canadian teachers during the COVID-19 pandemic, this case study moves beyond the consideration of individual strategies to reduce burnout, toward an examination of situational approaches to support teachers during this time of disruptive change. Using the Areas of Worklife Model, we present an analysis of in-depth interviews and focus groups with Canadian educational leaders on key transformational leadership approaches that were applied during the COVID-19 pandemic. In addition to observations about contextual factors which led to imbalance and adversity for teachers, insights were gained into leadership approaches which conversely increased balance and engagement resulting in overall enhanced teacher resilience. [ABSTRACT FROM AUTHOR]

Introduction: Predatory journals have been acknowledged as an increasing concern in the scholarly literature over the last decade, but research on the subject has been sparse. Research that has focused on predatory journals in the Canadian context has been even rarer, and limited to work focused on a single university. This study explores publishing trends in predatory journals by authors affiliated with Canadian universities. Methods: Articles published by authors at 30 Canadian universities, including all universities in the U15, were pulled from select predatory journals. Key data including author affiliation, article type, discipline, and grant information were extracted from the articles. Results: All universities in the study were found to have publications in predatory journals. The health sciences accounted for 72% of the publications, and the sciences for 20%. Research articles accounted for 50% of the articles. Opinion, editorial, or commentary pieces accounted for 24% and 19% were review articles. Grant funding was indicated in 34% of the articles, with NSERC and CIHR being top funders. The research-intensive U15 universities were found to publish more in predatory journals than their non-U15 compatriots, even when the universities were of similar size. Discussion: Canadian scholars were found to publish in predatory journals, particularly those scholars from the health sciences and research-intensive U15 universities. Grant funding was common, and often came from high profile funders like NSERC and CIHR. This study suggests that policy and education initiatives may be warranted in Canadian contexts, especially in the health sciences and at research-intensive universities. [ABSTRACT FROM AUTHOR]

• A dedicated program to support non-tenure track faculty facilitates scholarship initiatives. • Fostering and supporting non-tenure track scholarship is critical for advancing knowledge, strengthening student educational programs, as well as facilitating the promotion and retention of nurse clinician educators. [ABSTRACT FROM AUTHOR]

Dental fluorosis and hypocalcification manifest as white spot lesions and/or brown discolorations. With dental fluorosis, mottled layers in enamel can also be present depending on severity. Treatment options have varied in such situations, depending on severity, and can range from conservative to more invasive. This clinical report focuses on a combination of bleaching and resin infiltration as one of the more conservative treatment options. [ABSTRACT FROM AUTHOR]

Rationale and Objectives: The COVID-19 pandemic stresses the tenuous balance between domestic obligations and academic output for women across professions. Our investigation aims to evaluate the impact of the pandemic on the home duties and workplace productivity of academic radiologists with respect to gender.Materials and Methods: A 49-question survey was distributed to 926 members of Association of University Radiologists in October 2020. Several categories were addressed: demographics; workplace changes; stress levels and personal experiences with illness; time spent on domestic obligations; and perception of productivity during COVID-19. Statistical analyses were performed using SAS version 9.4 software (SAS Institute, Cary, NC).Results: A total of 96 responses across 30 states, 53.1% male and 46.9% female were received. Women report spending more time on unpaid domestic duties than men prior to COVID-19, with men spending a median of 5-10 h/wk and women spending a median of 10-15 h/wk (p = 0.043). With pandemic onset, both genders reported that women did more of the homecare, when not split equally. Women with young children reported a significant decrease in work-from-home productivity compared to men with young children (p = 0.007). Men reported they had more time to be productive compared to women (p = 0.012).Conclusion: The COVID-19 pandemic threatens to disrupt the advancement of women in radiology leadership roles by creating disparate effects on productivity due to increased workloads at home for women. This could potentially lead to decreases in promotions and research productivity in years to come that far outlast the acute phases of the pandemic. [ABSTRACT FROM AUTHOR]

Hydrogels with dynamically tunable crosslinking are invaluable for directing stem cell fate and mimicking a stiffening matrix during fibrosis or tumor development. The increases in matrix stiffness during tissue development are often accompanied by the accumulation of extracellular matrices (e.g., collagen, hyaluronic acid (HA)), a phenomenon that has received little attention in the development of dynamic hydrogels. In this contribution, we present a gelatin-based cell-laden hydrogel system capable of being dynamically stiffened while accumulating HA, a key glycosaminoglycans (GAG) increasingly deposited by stromal cells during tumor progression. Central to this strategy is the synthesis of a dually-modified gelatin macromer – gelatin-norbornene-carbohydrazide (GelNB-CH), which is susceptible to both thiol-norbornene photopolymerization and hydrazone click chemistry. We demonstrate that the crosslinking density of cell-laden thiol-norbornene hydrogels can be dynamically tuned via simple incubation with aldehyde-bearing macromers (e.g., oxidized dextran (oDex) or oHA). The GelNB-CH hydrogel system is highly cytocompatible, as demonstrated by in situ encapsulation of pancreatic cancer cells (PCC) and cancer-associated fibroblasts (CAF). This unique dynamic stiffening scheme provides a platform to study tandem accumulation of HA and elevation in matrix stiffness in the pancreatic tumor microenvironment. Hydrogels permitting on-demand and secondary crosslinking are ideal for mimicking a stiffening tumor microenvironment (TME). However, none of the current dynamic hydrogels account for both stiffening and accumulation of hyaluronic acid (HA), a major extracellular matrix component increasingly deposited in tumor stromal tissues, including pancreatic ductal adenocarcinoma (PDAC). The current work addresses this gap by developing a dynamic hydrogel system capable of simultaneously increasing stiffness and HA accumulation. This is achieved by a new gelatin macromer permitting sequential thiol-norbornene (for primary network crosslinking) and hydrazone click chemistry (for bioinert or biomimetic stiffening with oxidized dextran (oDex) or oHA, respectively). The results of this study provide new insights into how dynamically changing physicochemical matrix properties guide cancer cell fate processes. [Display omitted] [ABSTRACT FROM AUTHOR]

Copyright of Partnership: The Canadian Journal of Library & Information Practice & Research is the property of Ontario Library Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A 42-year-old man presented with a sporotrichoid lymphocutaneous infection for 1 month. The histopathology of the lesions showed numerous intracellular mycobacteria within foamy histiocytes suggestive of nontuberculous mycobacteria and misled the empiric treatment. The final culture grew Sporothrix spp. and the lesions improved with antifungal treatment alone. This case report depicts a case of Mycobacterium lentiflavum colonization in cutaneous sporotrichosis lesions on histopathology to raise awareness among physicians about this rare coincidence that could mislead the diagnosis. [ABSTRACT FROM AUTHOR]

Endosseous root-form implants are the most popular type of implant used today. However, patients may present with subperiosteal implants that need treatment with a removable prosthesis. This case report describes the fabrication of a new set of overdentures for 30-year-old subperiosteal implants using the patient's current dentures as a guide to establish a proper vertical dimension of occlusion and occlusal scheme. In addition, the patient's older set of dentures was used as the record bases in an effort to reuse the existing custom Dolder bar attachments. Esthetics and lip support were enhanced by selecting new teeth and adjusting the tooth positions. The patient was pleased with the esthetic and functional results of the new overdentures. [ABSTRACT FROM AUTHOR]

Enduring glass-ceramic restorations greatly depend on the quality of adhesion of the crown to enamel and dentin. Proper isolation is vital to the success of bonded ceramic restorations. The rubber dam has long been considered the primary method of preventing contamination of the operating field, a crucial requisite for adhesion. However, many dentists do not use rubber dam isolation due to its penchant for slowing down procedures. The authors present a case report that describes a technique for the indirect bonding of a ceramic restoration to a maxillary first molar using rubber dam isolation in conjunction with a floss ligature,a method that is aimed at optimizing operator effectiveness and efficiency. [ABSTRACT FROM AUTHOR]

Video games are an omnipresent component of contemporary culture that have shaped and influenced players and their behaviors. While gamification is a body of theory-laden knowledge that has emerged as a byproduct of the influence and reach of video games, little theorizing has been done about games, game design, and playstyles as indicators of player perceptions and behaviors. We explore this phenomenon with a qualitative study that examines how game design may influence players’ problem-solving and problem-setting, and how player problem-setting and -solving reveals their approaches as a player archetypes. Additionally, we investigate how such game design and gameplay may enhance Creative Self- Efficacy (CreaSE). Using content analysis, we examine how the game design of Antichamber models the application of reflective practice, how this design reveals players’ problem-solving and problem-setting skills through gameplay, and how players’ CreaSE is influenced by their experience and archetypes. We find that CreaSE is more malleable for certain player archetypes. In summary, we investigate how game design applies reflective practice, how the application of such theory influences players’ behavior, and its implications for CreaSE. [ABSTRACT FROM AUTHOR]

Background: The CanRisk Tool (https://canrisk.org) is the next-generation web interface for the latest version of the BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) state-of-the-art risk model and a forthcoming ovarian cancer risk model. Methods: The tool captures information on family history, rare pathogenic variants in cancer susceptibility genes, polygenic risk scores, lifestyle/hormonal/clinical features, and imaging risk factors to predict breast and ovarian cancer risks and estimate the probabilities of carrying pathogenic variants in certain genes. It was implemented using modern web frameworks, technologies, and web services to make it extensible and increase accessibility to researchers and third-party applications. The design of the graphical user interface was informed by feedback from health care professionals and a formal evaluation. Results: This freely accessible tool was designed to be user friendly for clinicians and to boost acceptability in clinical settings. The tool incorporates a novel graphical pedigree builder to facilitate collection of the family history data required by risk calculations. Conclusions: The CanRisk Tool provides health care professionals and researchers with a user-friendly interface to carry out multifactorial breast and ovarian cancer risk predictions. It is the first freely accessible cancer risk prediction program to carry the CE marking. [ABSTRACT FROM AUTHOR]

When we look closer to home--in the colleges and universities at which many of us work--we also see a system that parses its participants into those who are at the table and those who are on the margins. Which students are college-ready? Whose languages are valued? Which faculty members have tenure and voting rights? Who serves on which committees, and why? Whose ideas tend to be heard? Asking these questions can help us see who is on the inside and who is out, and can spur us to ask how we might reshape our institutions to be more inclusive. [ABSTRACT FROM AUTHOR]