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Speaking a second language influences jitter and shimmer when comparing monolingual English speakers with bilingual English-Spanish speakers. However, there is little information about differences on voice acoustic parameters when comparing monolingual Spanish speakers with bilingual Spanish-English speakers during their productions in Spanish. Determine differences in five voice acoustic parameters commonly used in voice assessments (fundamental frequency, jitter, shimmer, Harmonics-to-Noise Ratio and Cepstral Peak Prominence Smoothed) which may be influenced by bilingualism. Exploratory cross-sectional study with two groups of female participants: monolingual Spanish speakers (n = 17), and bilingual Spanish-English speakers (n = 11). Participants filled out a questionnaire and recorded two voice samples (sustained vowel /a/ and reading). For this study, all the participants reported that their native language was Spanish. Being a female bilingual speaker had a significant effect on Shimmer (%) with a Beta = -0.7. Similar tendency was found on harmonics-to-noise ratio (B = 0.2) and cepstral peak prominence smoothed (B = 0.2). Our results indicate that being a native Spanish female speaker, speaking English as a second language, has significant small effects on voice acoustic parameters, such as shimmer, harmonics-to-noise ratio and cepstral peak prominence smoothed, during their productions in Spanish. This information is of interest for assessment and intervention plans of bilingual speakers at clinical and work-related settings. [ABSTRACT FROM AUTHOR]

Occupational voice users are at a higher risk for developing voice disorders due to their vocal demands, such as prolonged periods of work-related voice use and nonideal environmental factors, such as speaking above background noise. The current study focused on the effects of background noise and hearing protection on acoustic-perceptual correlates of voice among steam train engineers. Fourteen participants phonated vowel /a/, read a phrase, and described a map under different noise and hearing protection conditions. Relative sound pressure level, relative fundamental frequency, and perceived vocal effort and disturbance decreased in the presence of hearing protection for all noise conditions. In contrast, these acoustic measures increased in the absence of hearing protection supporting Lombard effect. Overall, results of the current study provide insight into possible risks to vocal health in workers exposed to high levels of background noise and use hearing protection. [ABSTRACT FROM AUTHOR]

The Lombard effect (LE) is a phenomenon in which speakers adjust their vocal production by raising the volume in noisy environments. As a result, the LE can create problems of vocal strain, fatigue and potential injury. This study aims to examine the difference in vocal intensity output in subjects wearing unilateral hearing protection versus no hearing protection in the presence of background noise. Each subject was seated inside a sound booth wearing a head-mounted microphone. Subjects were asked to read an excerpt from "The Rainbow Passage" while various levels of background noise were played: 50, 60, 70, and 80 dBA (Multitalker Babble). Each noise level was played while the subject was with and without unilateral ear protection (Optime 98 Earmuff [3M]) in random order. The earmuff has a noise reduction rating of 25 dB. After each reading of the text, subjects were asked to rate communication disturbance, vocal clarity, and discomfort during talking using a 10 cm visual analogue scale. The LE is reduced from 0.38 dB/dB to 0.29 dB/dB with unilateral ear occlusion. However, self-perception of disturbance, clarity and comfort were not affected by unilateral occlusion, only by noise level. Unilateral hearing protection reduces the LE and may protect against phonotrauma when speaking in an environment with loud background noise. [ABSTRACT FROM AUTHOR]

Background: Anosmia and ageusia are symptoms commonly associated with COVID-19, but the relationship with disease severity, onset and recovery are unclear. Objective: To examine factors associated with anosmia and ageusia and the recovery from these symptoms in an ethnically diverse cohort. Methods: Individuals tested for SARS-CoV-2 between March and April 2020 were eligible for the study. Randomly selected participants answered a telephone questionnaire on COVID-19 symptoms with a focus on anosmia and ageusia. Additionally, relevant past medical history and data on the COVID-19 clinical course were obtained from electronic medical records. 486 patients were in the COVID-19 group and 103 were COVID-19-negative. Results: Patients who were younger were more likely to report anosmia and/or ageusia (odds ratio (OR) for anosmia per 1-year increase in age: 0·98, 95%CI:0–97-0·99, p = 0·003; for ageusia: 0·98, 95%CI:0·97-0·99, p = 0·005) as were patients with lower eosinophil counts (OR for anosmia per 0.1-K/μL increase in eosinophils: 0·02, 95%CI:0·001-0·46, p = 0·01, for ageusia 0·10, 95%CI:0·01-0·97, p = 0·047). Male gender was independently associated with a lower probability of ageusia (OR:0·56, 95%CI:0·38-0·82, p = 0·003) and earlier sense of taste recovery (HR:1·44, 95%CI:1·05-1·98, p = 0·02). Latinos showed earlier sense of taste recovery than white patients (HR:1·82, 95%CI:1·05-3·18, p = 0·03). Conclusion: Anosmia and ageusia were more common among younger patients and those with lower blood eosinophil counts. Ageusia was less commonly reported among men, and time to taste recovery was earlier among both men and Latinos. [ABSTRACT FROM AUTHOR]

The goals of the study were to (a) examine vocal fatigue in speech-language pathology students through subjective and objective measures following a novel 30-minute vocal loading task (VLT) and (b) evaluate the effects of psychosocial factors on vocal fatigue. Seventeen speech-language pathology students completed a 30-minute VLT using the LingWAVES software program. In addition to maintaining target intensity goals during reading a text, participants were also required to modify their pitch and voice quality. Vocal fatigue was measured subjectively using Vocal Fatigue Index and Borg vocal effort scale and objectively using variations of relative sound pressure level, fundamental frequency, pitch strength, smoothed cepstral peak prominence (CPPS), and acoustic voice quality index before, during, and after VLT. Participants provided information on their sleep quantity, stress, and depression through nonstandardized and standardized surveys. Results revealed that perceived effort and fatigue increased significantly after the 30-minute VLT. Acoustic measures of relative sound pressure level and fundamental frequency and increased systematically during and after the completion of task. All students were moderately stressed and measures related to pitch were highly related with perceived stress. The results of this study provide support for altering multiple vocal parameters to induce measurable changes in vocal fatigue following a short-duration VLT. [ABSTRACT FROM AUTHOR]

In addition to language differences in fundamental frequency between bilinguals and monolinguals, studies have also included other acoustic parameters to analyze differences in voice production associated with the language spoken. To identify differences in voice acoustic parameters during English productions between monolingual and bilingual English speakers. Exploratory cross-sectional study with two groups of subjects: monolingual English speakers (n = 40), and bilingual English-Spanish speakers (n = 13). Participants filled out a questionnaire and recorded one reading in English (second sentence of Rainbow passage "The rainbow is a division of white light into many beautiful colors") under a "virtual-simulated" acoustic condition of No Noise and Medium Reverberation Time (0.8 seconds). Analysis by gender shows that monolingual speakers had higher fundamental frequency mode, and lower standard deviation of fundamental frequency compared to bilingual English-Spanish speakers. Bilingual male speakers had higher jitter and harmonics-to-noise ratio than monolingual speakers. On the contrary, female bilingual speakers had lower jitter and shimmer than monolingual speakers. Speaking a second language may influence voice acoustic parameters, and therefore, should be considered when comparing acoustic speech metrics. [ABSTRACT FROM AUTHOR]

Background: The aim of the study was to evaluate local control and toxicities of strongly hypofractionated electron beam radiotherapy (RT) in elderly and fragile patients with facial nonmelanoma skin cancer (NMSC). Materials and methods: We enrolled patients aged ≥ 65 years with facial NMSC, Karnofsky Performance Status (KPS) ≥ 40 and life expectancy ≥ 6 months, amenable neither to daily RT nor surgery. Radiotherapy consisted of 35 Gy, delivered with 6 MeV electron beam, in 5 fractions of 7 Gy/day twice a week (tw). Prescription isodoses were 100% for cT1-cT2 and 90% for cT3-cT4. Objective response was assessed clinically 4 and 8 weeks after the end of RT and then monitored every 6 months. Side effects were assessed according to the CTCAE scale. Results: 12 patients of median age 89.5 years with a total of 23 NMSC cN0 achieved a median follow-up time of 6 months (range 1-10), with total treatment compliance. 10/12 patients had a 40 ≤ KPS < 70 and 2/12 a 70 ≤ KPS < 90. 5/12 patients had synchronous lesions. 22/23 lesions were classified as T1-T2 and had complete response (CR), 1/23 as T4 with partial response (PR). Within 4 weeks after the end of treatment, G1 toxicity was reported for 12/23 lesions, G2 for 8/23, G3 for 3/23, G4 for 0/23, all disappeared 8 weeks later, with or without topical therapy. After last follow-up (1 June 2020) 1/12 patients died with PR from senile marasmus, 11/12 are alive with CR and widely tolerated toxicities. Conclusions: Extreme hypofractionation of radiotherapy dose for facial NMSC is effective, safe and suitable for elderly patients. [ABSTRACT FROM AUTHOR]

Computer analysis of voice recordings is an integral part of the evaluation and management of voice disorders. In many practices, voice samples are taken in rooms that are not sound attenuated and/or sound-proofed; further, the technology used is rarely consistent. This will likely affect the recordings, and therefore, their analyses. The objective of this study is to compare various acoustic outcome measures taken from samples recorded in a sound-proofed booth to those recorded in more common clinic environments. Further, the effects from six different commonly used microphones will be compared. Thirty-six speakers were recorded while reading a text and producing sustained vowels in a controlled acoustic environment. The collected samples were reproduced by a Head and Torso Simulator and recorded in three clinical rooms and in a sound booth using six different microphones. Newer measures (eg, Pitch Strength, cepstral peak prominence, Acoustic Voice Quality Index), as well as more traditional measures (eg Jitter, Shimmer, harmonics-to-noise ratio and Spectrum Tilt), were calculated from the samples collected with each microphone and within each room. The measures which are more robust to room acoustic differences, background noise, and microphone quality include Jitter and smooth cepstral peak prominence, followed by Shimmer, Acoustic Voice Quality Index, harmonics-to-noise ratio, Pitch Strength, and Spectrum Tilt. The effect of room acoustics and background noise on voice parameters appears to be stronger than the type of microphone used for the recording. Consequently, an appropriate acoustical clinical space may be more important than the quality of the microphone. [ABSTRACT FROM AUTHOR]

Vocal loading tasks (VLTs) help researchers gather acoustic measurements and understand how a healthy speaker adjusts their voice in response to challenges. There is a dearth of evidence measuring the impact of speaking rate in VLTs on acoustic voice parameters and vocal fatigue. In the present study, the relationships between acoustic voice parameters and self-reported vocal fatigue were examined through an experimental VLT. 38 students completed a 45-minute VLT which involved the recording of three randomized reading tasks. The tasks varied by the speed in which the words were presented (slow, medium, fast) on a computer monitor. Vocal fatigue ratings were measured subjectively using a Borg scale and negative adaptations to vocal loading were measured objectively using Sound Pressure Level (SPL, in dBA), fundamental frequency (f o , in semitones), and phonation time (Dt %). Analysis indicated that vocal fatigue increases with time, and the slope of this relationship is affected by the speaking rate. SPL and f o increased with speaking rate and the standard deviation of SPL and f o decreased with speaking rate. On average, the male participants' phonation time values were 7.8% lower than the female participants. The rate of increase of vocal fatigue with time during the experiment was higher in the fast speaking style compared to the slow and medium ones. The results provide support that the novel VLT altered multiple vocal parameters to induce measurable changes in vocal fatigue. [ABSTRACT FROM AUTHOR]

The spatial prediction of growing stock volume is one of the most frequent application of remote sensing for supporting the sustainable management of forest ecosystems. For such a purpose data from active or passive sensors are used as predictor variables in combination with measures taken in the field in sampling plots. The Sentinel-2 (S2) satellites are equipped with a Multi Spectral Instrument (MSI) capable of acquiring 13 bands in the visible and infrared domains with a spatial resolution varying between 10 and 60 m. The present study aimed at evaluating the performance of the S2-MSI imagery for estimating the growing stock volume of forest ecosystems. To do so we used 240 plots measured in two study areas in Italy. The imputation was carried out with eight k-Nearest Neighbours (k-NN) methods available in the open source YaImpute R package. In order to evaluate the S2-MSI performance we repeated the experimental protocol also with two other sets of images acquired by two well-known satellites equipped with multi spectral instruments: Landsat 8 OLI and RapidEye scanner. We found that S2 worked better than Landsat in 37.5% of the cases and in 62.5% of the cases better than RapidEye. In one study area the best performance was obtained with Landsat OLI (RMSD = 6.84%) and in the other with S2 (RMSD = 22.94%), both with the k-NN system based on a distance matrix calculated with the Random Forest algorithm. The results confirmed that S2 images are suitable for predicting growing stock volume obtaining good performances (average RMSD for both the test areas of less than 19%). [ABSTRACT FROM AUTHOR]

(1) Determine the difference in vocal fry phonation in English and Spanish productions among bilingual young adults, (2) Characterize the effect of spoken language and native language on vocal fry production among English-Spanish bilingual speakers, (3) Identify the effect of first and second language knowledge of the listener in the voice perceptual assessment, and (4) Define the effect of the environment of the assessment (in situ vs. online), in the voice perceptual assessment. Exploratory cross-sectional study of 34 bilingual (Spanish-English) speakers and six inexperienced listeners. Participating speakers produced two speech samples (one in English and one in Spanish). Six inexperienced monolingual and bilingual listeners performed the voice perceptual assessment of vocal fry, General grade of hoarseness, and Roughness using a 4-point rating scale. Bilingual speakers used vocal fry more often when they were speaking in English (around 3%) compared with their production in Spanish (around 2%). Bilingual native English speakers used vocal fry more often during their productions in both languages compared with bilingual native Spanish speakers. Bilingual listeners had the highest agreement when identifying vocal fry in both languages. Differences in production of vocal fry between native speakers of American English and native speakers of Spanish may be evidence of transferring of vocal behavior (such as vocal fry) from one language to the second one. In addition, being a bilingual listener may have an important effect on the perceptual identification of voice quality in English and Spanish, as well as vocal fry in English. [ABSTRACT FROM AUTHOR]

Urban forests (UF) provide a range of important ecosystem services (ES) for human well-being. Relevant ES delivered by UF include urban temperature regulation, runoff mitigation, noise reduction, recreation, and air purification. In this study the potential of air pollution removal by UF in the city of Florence (Italy) was investigated. Two main air pollutants were considered – particulate matter (PM 10 ) and tropospheric ozone (O 3 ) – with the aim of providing a methodological framework for mapping air pollutant removal by UF and assessing the percent removal of air pollutant. The distribution of UF was mapped by high spatial resolution remote sensing data and classified into seven forest categories. The Leaf Area Index (LAI) was estimated spatially using a regression model between in-field LAI survey and Airborne Laser Scanning data and it was found to be in good linear agreement with estimates from ground-based measurements (R 2 = 0.88 and RMSE% = 11%). We applied pollution deposition equations by using pollution concentrations measured at urban monitoring stations and then estimated the pollutant removal potential of the UF: annual O 3 and PM 10 removal accounted for 77.9 t and 171.3 t, respectively. O 3 and PM 10 removal rates by evergreen broadleaves (16.1 and 27.3 g/m 2 ), conifers (10.9 and 28.5 g/m 2 ), and mixed evergreen species (15.8 and 31.7 g/m 2 ) were higher than by deciduous broadleaf stands (4.1 and 10 g/m 2 ). However, deciduous forests exhibited the largest total removal due to the high percentage of tree cover within the city. The present study confirms that UF play an important role in air purification in Mediterranean cities as they can remove monthly up to 5% of O 3 and 13% of PM 10 . [ABSTRACT FROM AUTHOR]

The conservation of biological diversity is recognized as a fundamental component of sustainable development, and forests contribute greatly to its preservation. Structural complexity increases the potential biological diversity of a forest by creating multiple niches that can host a wide variety of species. To facilitate greater understanding of the contributions of forest structure to forest biological diversity, we modeled relationships between 14 forest structure variables and airborne laser scanning (ALS) data for two Italian study areas representing two common Mediterranean forests, conifer plantations and coppice oaks subjected to irregular intervals of unplanned and non-standard silvicultural interventions. The objectives were twofold: (i) to compare model prediction accuracies when using two types of ALS metrics, echo-based metrics and canopy height model (CHM)-based metrics, and (ii) to construct inferences in the form of confidence intervals for large area structural complexity parameters. Our results showed that the effects of the two study areas on accuracies were greater than the effects of the two types of ALS metrics. In particular, accuracies were less for the more complex study area in terms of species composition and forest structure. However, accuracies achieved using the echo-based metrics were only slightly greater than when using the CHM-based metrics, thus demonstrating that both options yield reliable and comparable results. Accuracies were greatest for dominant height (Hd) (R 2 = 0.91; RMSE% = 8.2%) and mean height weighted by basal area (R 2 = 0.83; RMSE% = 10.5%) when using the echo-based metrics, 99th percentile of the echo height distribution and interquantile distance. For the forested area, the generalized regression (GREG) estimate of mean Hd was similar to the simple random sampling (SRS) estimate, 15.5 m for GREG and 16.2 m SRS. Further, the GREG estimator with standard error of 0.10 m was considerable more precise than the SRS estimator with standard error of 0.69 m. [ABSTRACT FROM AUTHOR]

The agarophyte family Gelidiellaceae currently includes 26 species in two genera, Gelidiella and Parviphycus, but the generic status and species boundaries have not been fully explored. In order to resolve taxonomic issues in the family, we analyzed mitochondria-encoded coxl and plastid-encoded rbcL and psaA genes from types and fresh collections including topotype material. The Gelidiellaceae was resolved with five distinct groups, interpreted here as representing five genera: (1) Gelidiella, including the type, (2) Huismaniella gen. nov., (3) Millerella gen. nov., (4) Parviphycus s.str. including the type, and (5) Perronella gen. nov. Gelidiella was recognized as including a new species, G.flabella, that is described for specimens from Madagascar. A new genus, Huismaniella, is described for the species previously known as Gelidiella ramellosa, characterized by lateral tetrasporangial branchlets inserted at right angles on erect axes and irregularly arranged tetrasporangia. Parviphycus includes P. adnatus which is characterized by simple thalli with tetrasporangial branchlets formed directly on prostate axes and holdfasts forming continuous fringes along the entire length of prostrate axes. The new genus Millerella is described to accommodate five species previously known as Gelidiella or Parviphycus, characterized by tetrasporangial sori formed on erect axes or branches and unicellular rhizoids forming irregular clumps along prostrate axes. Perronella gracilis gen. et sp. nov. is described for plants with terete axes, multifarious branching, and monosporangia formed on erect axes and branches. The implications for nomenclature, taxonomic revisions, and biogeography in the Gelidiellaceae are discussed. [ABSTRACT FROM AUTHOR]

Summary Background Previous research suggests that classically trained professional singers rely not only on external auditory feedback but also on proprioceptive feedback associated with internal voice sensitivities. Objectives The Lombard effect and the relationship between sound pressure level (SPL) and external auditory feedback were evaluated for professional and nonprofessional singers. Additionally, the relationship between voice quality, evaluated in terms of singing power ratio (SPR), and external auditory feedback, level of accompaniment, voice register, and singer gender was analyzed. Methods The subjects were 10 amateur or beginner singers and 10 classically trained professional or semiprofessional singers (10 men and 10 women). Subjects sang an excerpt from the Star-Spangled Banner with three different levels of the accompaniment, 70, 80, and 90 dBA and with three different levels of external auditory feedback. SPL and SPR were analyzed. Results The Lombard effect was stronger for nonprofessional singers than professional singers. Higher levels of external auditory feedback were associated with a reduction in SPL. As predicted, the mean SPR was higher for professional singers than nonprofessional singers. Better voice quality was detected in the presence of higher levels of external auditory feedback. Conclusions With an increase in training, the singer's reliance on external auditory feedback decreases. [ABSTRACT FROM AUTHOR]

Noise generated from human activities (in particular by infrastructure and construction sites) can have a strong impact on the physiology and behavior of birds. In this work, a quantitative method for evaluating the impact of noise on wild birds is proposed. The method combines the results of previous studies that considered the effect of noise on birds and involved noise mapping evaluations. A forecast noise simulation was used to generate maps of (1) signal masking areas and (2) potential density variation. These results allow the determination of the highest risk areas for wild birds. [ABSTRACT FROM AUTHOR]

We investigated the potential performance of air pollution removal by the green infrastructures and urban forests in the city of Florence, central Italy, with a focus on the two most detrimental pollutants for human health: particulate (PM 10 ) and ozone (O 3 ). The spatial distribution of green infrastructures was mapped using remote sensing data. A spatial modeling approach using vegetation indices, Leaf Area Index, and local pollution concentration data was applied to estimate PM 10 and O 3 removal. The results are discussed to highlight the role and potential of green infrastructures and urban forests in improving air quality in Southern European cities. [ABSTRACT FROM AUTHOR]

Purpose To compare five liver metastasis stereotactic ablative radiotherapy (SABR) plans optimised in fourteen centres with 3D-Conformal-RT, IMRT, VMAT, CyberKnife and Tomotherapy and identify possible dosimetric differences. Methods Dose prescription was 75 Gy in 3 fractions, normalised at 67%–95% isodose. Results Excluding few cases, all institutions achieved the planning objectives. Differences up to 40% and 25% in mean dose to liver and PTV were found. No significant correlations between technological factors and DVH for target and OARs were observed; the optimisation strategies selected by the planners played a key role in the planning procedure. Conclusions The human factor and the constraints imposed to the target volume have a greater dosimetric impact than treatment planning and radiation delivery technology in stereotactic treatment of liver metastases. Significant differences found both in terms of dosimetric target coverage and OAR sparing should be taken into consideration before starting a multi-institutional SARB clinical trial. [ABSTRACT FROM AUTHOR]

School teachers have an elevated risk of voice problems. The results of three studies investigating this elevated risk in terms of speaking environments teachers’ encounter at work are presented. In the first study, 57 teachers were observed for 2 weeks (waking hours), comparing voice use in the school environment and in non-school environments. In a second study, 45 participants performed a short vocal task multiple times in two different rooms: a variable acoustic room and an anechoic chamber. Each time they entered the variable acoustics room, the reverberation time and/or the background noise condition had been modified. Besides being having their speech recorded, subjects responded to questions about their vocal comfort and their perception of changes in the acoustic environment. In a third study, 20 untrained vocalists performed a simple vocal task in the following conditions: with and without background babble and with and without transparent plexiglass shields to increase the first reflection. Relationships were examined between [1] the results for the room acoustic parameters; [2] the subjects’ perception of the room; and [3] the recorded speech acoustic. From these three studies several gender differences were found; some of those differences held for each room condition (reverberation, noise level, and early reflection). [ABSTRACT FROM AUTHOR]

The relationship between walkable access to healthy food sources and risk of anemia in pregnancy was evaluated for a cohort of 4678 women who initiated prenatal care in the year 2010 at an academic medical center in Bronx, New York. After geocoding patient residences, street network distances were obtained for the closest healthy food sources, which were identified from multiple databases. For lower-income patients, as indicated by Medicaid or lack of health insurance, those who lived less than 0.25 miles from a healthy food source were less likely to be anemic when compared to those who lived farther (adjusted OR = 0.65, 95% CI 0.48, 0.88). Patients with commercial insurance showed no effect. These results help to understand how a nutritionally-mediated condition such as anemia during pregnancy can be affected by one’s built environment, while also highlighting the importance of conditioning on socioeconomic status for these types of studies. [ABSTRACT FROM AUTHOR]

Objective: To evaluate reproducibility of oral rinse self-collection for human papillomavirus (HPV) detection and investigate associations between oral HPV, oral lesions, immune and sociodemographic factors, we performed a cross-sectional study of older adults with human immunodeficiency virus (HIV) infection. Study Design: We collected oral rinse samples from 52 subjects at 2 different times of day, followed by an oral examination and interview. We identified HPV with the use of polymerase chain reaction platforms optimized for detection of mucosal and cutaneous types. Results: Eighty-seven percent of individuals had oral HPV, of which 23% had oncogenic alpha, 40% had nononcogenic alpha, and 46% had beta or gamma HPV. Paired oral specimens were concordant in all parameters tested. Significant associations observed for oral HPV with increased HIV viral load, hepatitis C seropositivity, history of sexually transmitted diseases, and lifetime number of sexual partners. Conclusions: Oral cavity may be a reservoir of subclinical HPV in older adults who have HIV infection. Understanding natural history, transmission, and potential implications of oral HPV warrants further investigations. [ABSTRACT FROM AUTHOR]

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Vocal instructors during their normal workday are exposed to high noise levels that can affect their voice and hearing health. The goal of this study was to evaluate the voice and hearing status of voice instructors before and after lessons and relate these evaluations with voice and noise dosimetry taken during lessons. Eight voice instructors volunteered to participate in the study. The protocol included (1) questionnaires, (2) pre/post assessment of voice quality and hearing status, and (3) voice and noise dosimetry during lessons. Acoustic measurements were taken of the unoccupied classrooms. In six of eight classrooms, the measured noise level was higher than the safety recommendations set by National Institute for Occupational Safety and Health. The background noise level and the reverberation time in the classrooms were in compliance with the national standard recommendations. We did not find a clear pattern comparing pre- and post-measurements of voice quality consistent among genders. In all subjects, the Sound Pressure Levels mean increased, and the standard deviation of fundamental frequency decreased indicating association to vocal fatigue. Previous studies link these changes to increasing vocal fatigue. The audiometric results revealed seven out of eight instructors have sensorineural hearing loss. The interaction of the acoustic space and noise levels can contribute to the development of hearing and voice disorders for voice instructors. If supported by larger sample size, the results of this pilot study could justify the need for a hearing and voice conservation program for music faculty. [ABSTRACT FROM AUTHOR]

Secondary or pathologic fractures, associated with osteosarcoma, have been considered for a long time a negative prognosis regarding its evolution in the patients. The aim of this study was to evaluate the prognostic importance of such pathologic fractures in osteosarcoma patients receiving new therapies as well as the best conditions for surgery aiming at "limbs salvage". On a total of 22 patients affected by osteosarcoma, we performed a retrospective study with 12 patients showing pathologic fractures caused by osteosarcoma and 10 patients without any pathologic fracture. The patients enrolled into Timisoara University Hospital have been followed up along 5 years or until a reappearance of either the disease or metastases, distant or local. [ABSTRACT FROM AUTHOR]

The effects on sexual behaviour of acute low doses of methylendioxymethamphetamine (MDMA) (0.3, 1, 3 mg/kg/i.p.), alone or in combination with exposure to loud music (1 h stimulation), were investigated in Wistar rats. Results indicate that acute MDMA, at dose of 3 mg/kg, notably impaired copulatory behavior of sexually experienced male rats. In particular, MDMA-exposed animals exhibited a significant increase in intromission and ejaculation latencies as well as a significant decrease in percentage of rats displaying copulatory activity (one intromission at least). Surprisingly, one hour exposure to loud music, which per se resulted ineffective, antagonized the suppressive effect of MDMA by increasing the percent of animals displaying sexual activity. However, combined treatment of MDMA and music stimulation did not fully restore normal sexual behavior as the animals reaching ejaculation still showed a marked reduction of copulatory efficiency. These findings demonstrate that the systemic administration of a single low dose of MDMA, alone or in combination with loud music, which is commonly present in certain environments such as rave parties, notably impairs copulatory activity of male rats. [ABSTRACT FROM AUTHOR]

Gestational diabetes mellitus (GDM) should be regarded as a sentinel event in a woman’s life that presents challenges and disease prevention opportunities to all providers of health care for women of reproductive age. Prediabetic risk factors are rising in prevalence and include dietary and lifestyle habits, which when superimposed on genetic predisposition contribute to the rising prevalence of type 2 diabetes and GDM. There is growing evidence that treatment of GDM matters, with a continuum of adverse pregnancy outcome risks proportional to degrees of maternal glucose intolerance. GDM in an index pregnancy increases the risk of recurrent GDM in subsequent pregnancies, and recurrence rates of up to 70% have been reported. GDM recurrence rates are influenced by maternal health characteristics and past pregnancy history. The risk of later metabolic syndrome and type 2 diabetes is increased in women with a history of GDM and women should be screened for postpartum glucose intolerance. Opportunities to prevent recurrent GDM and later type 2 diabetes require attention to risk factors and plasma glucose status with identification of impaired fasting glucose or impaired glucose tolerance. [Copyright &y& Elsevier]

This article explores the employment of the physical and mechanical nature of Roman hydraulic concrete in the maritime infrastructure of the Roman Mediterranean world. It examines the sourcing of the various components of the building material during the period. It discusses the results of an experiment carried out with carefully-duplicated Roman materials and construction technology. It suggests that builders during the period used wicker baskets to carry mortar from the mixing area to its place of deposition.