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1. MHC-II Deficiency Among Egyptians: Novel Mutations and Unique Phenotypes

Author

El Hawary, Rabab E., Mauracher, Andrea A., Meshaal, Safa S., Eldash, Alia, Abd Elaziz, Dalia S., Alkady, Radwa, Lotfy, Sohilla, Opitz, Lennart, Galal, Nermeen M., Boutros, Jeannette A., Pachlopnik Schmid, Jana, and Elmarsafy, Aisha M.

Abstract

MHC class II deficiency leads to defective CD4+T-cell function that results from impaired antigen presentation. A genetic disorder in 1 of 4 genes results in this syndrome that is associated with the clinical phenotype of combined immunodeficiency.

Published
2019
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