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2. Gestational diabetes and fetal growth acceleration: induction of labour versus expectant management.

Author

ALBERICO, S., BUSINELLI, C., WIESENFELD, U., ERENBOURG, A., MASO, G., PICCOLI, M., and RONFANI, L.

Subjects
CESAREAN section, ELECTIVE surgery, GESTATIONAL diabetes, FETAL development, OBESITY, RANDOMIZED controlled trials
Abstract

The article discusses a study on the association between a significant variation in C-section rate and macrosomia incidence and the elective induction of labour at 38 weeks compared to expectant management in A1 and A2 gestational diabetes (GDM) pregnancies with fetal growth acceleration. Women diagnosed with GDM and fetal growth acceleration at 38 weeks of gestation were included in the study. It aims to verify whether induction of labour as against expectant management can determine a difference in the odds of C-section in women with GDM and fetal growth acceleration. It indicates a positive trend in terms of C-section rate and neonatal outcomes in women undertaking induction particularly if obese.

Published
2010

3. Diagnosis of HIV infection in pregnancy: data from a national cohort of pregnant women with HIV in ItalyThis paper was presented in part at the 17th ANLAIDS National Conference on AIDS, Rome, 28–30 November 2003; and at the World Conference ‘Securing treatment and care for people living with HIV. Low-income countries: where are we now?’, Florence, 21–24 January 2004.

Author

FLORIDIA, M., RAVIZZA, M., TAMBURRINI, E., ANZIDEI, G., TIBALDI, C., MACCABRUNI, A., GUARALDI, G., ALBERICO, S., VIMERCATI, A., ANTONI, A. DEGLI, and FERRAZZI, E.

Abstract

We analysed the characteristics of the pregnancies with a previously undetected HIV infection in a national observational study of pregnant women with HIV in Italy. In a total of 443 pregnancies with available date of HIV diagnosis, 118 were characterized by a previously undetected HIV infection (26·6%, 95% CI 22·5–30·8). The following factors were independently associated with this occurrence in a multivariate analysis (adjusted odds ratios; 95% CIs): foreign nationality (5·1, 2·8–9·3); no pre-conception counselling (35·9, 4·8–266·1); first pregnancy (2·1, 1·2–4·0); asymptomatic status (6·8, 1·5–30·6). Women with previously undetected infection started antiretroviral treatment significantly later during pregnancy (P<0·001). Missed diagnosis was responsible for one case of transmission. A high rate of previously undetected HIV infection was observed. This suggests a good HIV detection during pregnancy, but also the need to reinforce HIV testing strategies among women of childbearing age. We identified some determinants which may be considered for intervention measures.

Published
2006

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