133 results on '"BEAULIEU, JEAN"'
Search Results
2. AIRS: ARIEL IR spectrometer development status
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Coyle, Laura E., Matsuura, Shuji, Perrin, Marshall D., Martignac, Jérôme, Amiaux, Jerome, Capocci, Thomas, Bataillon, Clara, Baumann, Marion, Berthé, Michel, Cara, Christophe, Delisle, Cyrille, Direk, Achrène, Dumaye, Luc, Fontignie, Jean, Horeau, Benoît, Hurtado, Norma, Huynh, Duc-Dat, Kaszubiak, Grégory, Lagage, Pierre-Olivier, Le Mer, Isabelle, Leguay, Nathan, Lortholary, Michel, Moreau, Vincent, Mulet, Patrick, Pichon, Thibault, Provost, Léna, Reboul, Bastien, Renaud, Diana, Talvard, Michel, Tourrette, Thierry, Visticot, François, Arhancet, Axel, Bachet, Damien, Berton, Nicolas, Cossou, Christophe, Drouen, Yannick, Lacroix, Mickaël, Picault, Lexane, Le Provost, Hervé, Meyer, Virgile, Solenne, Nicolas, Tellier, Olivier, Arondel, Antoine, Crane, Bruno, Dubois, Jean-Pierre, de Jabrun, Clémence, Langlet, François, Le Claire, Dylan, Lecomte, Benoît, Maillot, Antoine, Morinaud, Gilles, Ollivier, Marc, Philippon, Anne, Tamiatto, Catherine, Tosti, Stéphane, Zhang, Xueyan, Lapeyrere, Vincent, Bonafous, Marion, Parisot, Jérôme, Pechevis, Eitan, Reess, Jean-Michel, Zegadanin, Didier, Beaulieu, Jean-Philippe, Batista, Virginie, Drossart, Pierre, Fahmy, Salma, Jollet, Delphine, Puig, Ludovic, Tirolien, Thierry, Salvignol, Jean-Christophe, Baldit, Elisa, Danto, Pascale, Hervet, Gilles, Le Huedet, Yann, Maisonnave, Océane, Eccleston, Paul, Drummond, Rachel, Bishop, Georgia, Bruzzi, Davide, Caldwell, Andrew, Caldwell, Martin, Desjonqueres, Lucile, Whalley, Martin, Pascale, Enzo, Morgante, Gianluca, Focardi, Mauro, Pace, Emanuele, Di Giorgio, Anna Maria, Ligori, Sebastiano, Défossé, Adrien, and Guerrier, Mallaury
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- 2024
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3. Radial and median nerves distal peripheral tension after reverse shoulder arthroplasty: a cadaveric study
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Cunningham, Gregory, Bernardo, Lauryne, Brandariz, Rodrigo, Holzer, Nicolas, Da Rocha, Daniel, and Beaulieu, Jean-Yves
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Peripheral nerve injury is a recognized complication after reverse shoulder arthroplasty (RSA) that has mainly been studied at the level of the brachial plexus and its proximal branches. However, the impact of RSA on distal peripheral nerves and the influence of elbow and wrist position is not known. This cadaveric study aimed to analyze the effect of RSA implantation and upper limb position on tension in the distal median and radial nerves. The hypothesis was that RSA increased distal nerve tension, which could be further affected by elbow and wrist position.
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- 2024
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4. Midsectional Magnetic Resonance Imaging Analysis of the Sigmoid Notch of the Distal Radioulnar Joint
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Mauler, Flavien, Boudabbous, Sana, and Beaulieu, Jean-Yves
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- 2023
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5. Suzanne de Nervèze polygraphe: les modulations du discours moral dans les Pensées chrestiennes et morales (1662).
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Beaulieu, Jean-Philippe
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SPIRITUALITY ,ETHICS ,DISPOSITION (Philosophy) ,CONDUCT of life ,PAMPHLETS - Abstract
Très diversifiés sur le plan générique, les quelque 36 imprimés que signe Suzanne de Nervèze entre 1636 et 1662 forment une production unifiée par une posture auctoriale de moraliste qui embrasse la spiritualité et la philosophie. Cette posture est particulièrement perceptible dans le tout dernier livre de Nervèze, Les Pensées chrestiennes et morales (1662), qui réunit une vingtaine de textes déclinant la réflexion morale d'abord sur un mode spirituel, avant de s'engager davantage du côté d'une critique des moeurs. Reprenant la matière et la forme de plusieurs écrits antérieurs où l'autrice se prononce tant sur la conduite de l'âme que sur celle de l'État, ce recueil confirme une disposition polygraphique qui semble associée à un désir de démontrer sa compétence de femme de lettres, comme le révèle l'attention portée tant à la forme des discours qu'à leur déploiement. [ABSTRACT FROM AUTHOR]
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- 2021
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6. Ultrasound of the ulnar–palmar region of the wrist: normal anatomy and anatomic variations.
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Bianchi, Stefano, Beaulieu, Jean-Yves, and Poletti, Pierre-Alexandre
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Ultrasound (US) assessment of the wrist is frequently used for the evaluation of carpal tunnel due to high frequency of local compression of the median nerve (MN), but the ulnar–palmar wrist region (UPWR) has received limited attention in the medical literature. The possibilities of US in the assessment of UPWR are therefore likely underestimated by sonologists. This review article is focused on the US assessment of the normal anatomy and anatomic variations of the UPWR. The anatomy of this region of the wrist is complex and less studied than the radial side. In an effort to simplify it and to present it didactically, we have divided this region in three parts on the basis of osseous landmarks. Our review indicates sonography is effective in identifying the UPWR and related disorders, and is thus a valuable tool for ensuring appropriate management of a variety of disorders. [ABSTRACT FROM AUTHOR]
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- 2020
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7. Ultrasound of local complications in hand surgery: a pictorial essay.
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Bianchi, Stefano, Beaulieu, Jean-Yves, and Poletti, Pierre-Alexandre
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Early detection of local complications (venipuncture complications, nerve lesions, infections, arthritis, and tenosynovitis, tendon adhesions and re-tears, complications related to orthopaedic hardware) after hand surgery is required for prompt treatment. Ultrasound has proven to be a valuable imaging modality for detecting and assessing a variety of disorders of the wrist and hand. The purpose of this pictorial essay is to present a wide range of complications after wrist and hand surgery assessed by ultrasound. [ABSTRACT FROM AUTHOR]
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- 2020
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8. Genomic prediction for hastening and improving efficiency of forward selection in conifer polycross mating designs: an example from white spruce
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Lenz, Patrick R. N., Nadeau, Simon, Azaiez, Aïda, Gérardi, Sébastien, Deslauriers, Marie, Perron, Martin, Isabel, Nathalie, Beaulieu, Jean, and Bousquet, Jean
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Genomic selection (GS) has a large potential for improving the prediction accuracy of breeding values and significantly reducing the length of breeding cycles. In this context, the choice of mating designs becomes critical to improve the efficiency of breeding operations and to obtain the largest genetic gains per time unit. Polycross mating designs have been traditionally used in tree and plant breeding to perform backward selection of the female parents. The possibility to use genetic markers for paternity identification and for building genomic prediction models should allow for a broader use of polycross tests in forward selection schemes. We compared the accuracies of genomic predictions of offspring’s breeding values from a polycross and a full-sib (partial diallel) mating design with similar genetic background in white spruce (Picea glauca). Trees were phenotyped for growth and wood quality traits, and genotyped for 4092 SNPs representing as many gene loci distributed across the 12 spruce chromosomes. For the polycross progeny test, heritability estimates were smaller, but more precise using the genomic BLUP (GBLUP) model as compared with pedigree-based models accounting for the maternal pedigree or for the reconstructed full pedigree. Cross-validations showed that GBLUP predictions were 22–52% more accurate than predictions based on the maternal pedigree, and 5–7% more accurate than predictions using the reconstructed full pedigree. The accuracies of GBLUP predictions were high and in the same range for most traits between the polycross (0.61–0.70) and full-sib progeny tests (0.61–0.74). However, higher genetic gains per time unit were expected from the polycross mating design given the shorter time needed to conduct crosses. Considering the operational advantages of the polycross design in terms of easier handling of crosses and lower associated costs for test establishment, we believe that this mating scheme offers great opportunities for the development and operational application of forward GS.
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- 2020
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9. Non-integrin laminin receptors in epithelia.
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Cloutier, Gabriel, Sallenbach-Morrissette, Amélie, and Beaulieu, Jean-François
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CELL receptors ,EPITHELIAL cells ,CELL physiology ,EXTRACELLULAR matrix ,CELL anatomy ,SMALL intestine - Abstract
Highlights • Laminin is an important component of the epithelial cell microenvironment. • Besides integrins, epithelial cells express a variety of receptors for laminin. • Dystroglycan and the 37/67 LR are two of these laminin receptors. Abstract The interactions between cells and the extracellular matrix (ECM) play a major role in normal and pathological conditions. The ECM can modulate several biological functions including cell proliferation, adhesion, differentiation and survival through its interactions with cell receptors. Laminins are one of the most important glycoproteins present in basement membranes, a type of ECM. The pattern of expression of its different isoforms depends on the spatiotemporal organization of each tissue. While integrins are the most studied laminin receptors, other non-integrin laminin receptors are also involved. This review focuses on two particular non-integrin laminin receptors in the epithelial context: dystroglycan and 37/67 laminin receptor (37/67LR). Dystroglycan is a two-subunit protein discovered in the muscle as part of the dystrophin-associated glycoprotein complex. This protein can also be found in many epithelia where its roles are variable. The 37/67LR is a still incompletely understood laminin receptor that is important to regulate intestinal epithelial cell function and could be involved in various pathological conditions. [ABSTRACT FROM AUTHOR]
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- 2019
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10. Pedicled superficial inferior epigastric artery flap in hand reconstruction
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Cuenca, Céline, Balagué, Nicolas, Beaulieu, Jean-Yves, and Bouvet, Cindy
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- 2024
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11. A miR-137–Related Biological Pathway of Risk for Schizophrenia Is Associated With Human Brain Emotion Processing
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Pergola, Giulio, Rampino, Antonio, Sportelli, Leonardo, Borcuk, Christopher James, Passiatore, Roberta, Di Carlo, Pasquale, Marakhovskaia, Aleksandra, Fazio, Leonardo, Amoroso, Nicola, Castro, Mariana Nair, Domenici, Enrico, Gennarelli, Massimo, Khlghatyan, Jivan, Kikidis, Gianluca Christos, Lella, Annalisa, Magri, Chiara, Monaco, Alfonso, Papalino, Marco, Parihar, Madhur, Popolizio, Teresa, Quarto, Tiziana, Romano, Raffaella, Torretta, Silvia, Valsecchi, Paolo, Zunuer, Hailiqiguli, Blasi, Giuseppe, Dukart, Juergen, Beaulieu, Jean Martin, and Bertolino, Alessandro
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miR-137 is a microRNA involved in brain development, regulating neurogenesis and neuronal maturation. Genome-wide association studies have implicated miR-137 in schizophrenia risk but do not explain its involvement in brain function and underlying biology. Polygenic risk for schizophrenia mediated by miR-137 targets is associated with working memory, although other evidence points to emotion processing. We characterized the functional brain correlates of miR-137 target genes associated with schizophrenia while disentangling previously reported associations of miR-137 targets with working memory and emotion processing.
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- 2024
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12. Le positionnement de la cupule d’une prothèse trapézo-métacarpienne a-t-il une incidence dans l’apparition postopératoire d’une ténosynovite de De Quervain ?
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Cuenca, Céline, Rime, Jacques, Gonzalez, Amanda, and Beaulieu, Jean-Yves
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Les prothèses de type Touch et Moovis sont des arthroplasties trapézo-métacarpiennes à double mobilité. La littérature montre un taux de descellement.
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- 2023
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13. La ligamentoplastie slic dans instabilités périscaphoïdiennes aiguës et subaiguës
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Piguet, Emmanuel, Davat, Marie, and Beaulieu, Jean-Yves
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Le traitement des instabilités périscaphoïdiennes sont un challenge thérapeutique. Que ce soit dans le cadre des lésions scapholunaires ou péri-lunaires, de nombreuses techniques de réparations ou de reconstructions ont été proposées.
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- 2023
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14. Heartbeat-enhanced immersive virtual reality to treat complex regional pain syndrome.
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Solcà, Marco, Ronchi, Roberta, Bello-Ruiz, Javier, Schmidlin, Thomas, Herbelin, Bruno, Luthi, François, Konzelmann, Michel, Beaulieu, Jean-Yves, Delaquaize, François, Schnider, Armin, Guggisberg, Adrian G., Serino, Andrea, and Blanke, Olaf
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- 2018
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15. Effect of Ketoprofen and ATB-352 on the Immature Human Intestine
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Thibault, Marie-Pier, Tremblay, Éric, Wallace, John L., and Beaulieu, Jean-François
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The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a broad spectrum of life-threatening adverse effects on the immature gastrointestinal tract. NSAID derivatives exploiting the beneficial effects of biologically active gases, such as hydrogen sulfide (H2S), have been developed. Herein, we determined the effects of ketoprofen and ATB-352, a H2S-releasing ketoprofen derivative, on selected metabolic pathways previously identified to be significantly altered by indomethacin in the human immature intestine. Ketoprofen and ATB-352 were tested on human mid-gestation small intestinal explants maintained in a serum-free organ culture system for 48 hours. The expression levels of the representative genes involved in selected metabolic pathways were measured by real-time PCR after a treatment of 48 hours. Tested at a concentration that allows more than 80% inhibition of PGE2 production, ketoprofen was found to be less damaging than indomethacin at an equivalent dosage. However, based on the inducibility of cyclooxygenase-2 transcript expression, we were able to discriminate between responder individuals in which the deleterious effects observed with indomethacin were attenuated, and non-responder specimens in which the effects were similar to those observed with indomethacin. ATB-352 did not induce significant changes compared to ketoprofen on these metabolic pathways. These results show less damaging effects of ketoprofen compared to indomethacin on the immature intestine and indicate that the intestinal response to this NSAID significantly varies between individuals. However, the results did not allow us to demonstrate a specific beneficial effect of H2S release in organ culture.
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- 2019
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16. 5-HT3Receptor Antagonists in Neurologic and Neuropsychiatric Disorders: The Iceberg Still Lies beneath the Surface
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Fakhfouri, Gohar, Rahimian, Reza, Dyhrfjeld-Johnsen, Jonas, Zirak, Mohammad Reza, and Beaulieu, Jean-Martin
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5-HT3receptor antagonists, first introduced to the market in the mid-1980s, are proven efficient agents to counteract chemotherapy-induced emesis. Nonetheless, recent investigations have shed light on unappreciated dimensions of this class of compounds in conditions with an immunoinflammatory component as well as in neurologic and psychiatric disorders. The promising findings from multiple studies have unveiled several beneficial effects of these compounds in multiple sclerosis, stroke, Alzheimer disease, and Parkinson disease. Reports continue to uncover important roles for 5-HT3receptors in the physiopathology of neuropsychiatric disorders, including depression, anxiety, drug abuse, and schizophrenia. This review addresses the potential of 5-HT3receptor antagonists in neurology- and neuropsychiatry-related disorders. The broad therapeutic window and high compliance observed with these agents position them as suitable prototypes for the development of novel pharmacotherapeutics with higher efficacy and fewer adverse effects.
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- 2019
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17. Accelerating the selection process for Populus and Salix clones using short-term photosynthetic acclimation responses under greenhouse conditions.
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Mamashita, Takamitsu, Larocque, Guy R., DesRochers, Annie, Beaulieu, Jean, Thomas, Barb R., Mosseler, Alex, Major, John, and Sidders, Derek
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PHOTOSYNTHESIS ,NITROGEN ,POPLARS ,LEAF area ,CARBON dioxide - Abstract
Copyright of Ecoscience (Ecoscience) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2017
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18. The ARIEL space mission
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Lystrup, Makenzie, MacEwen, Howard A., Fazio, Giovanni G., Batalha, Natalie, Siegler, Nicholas, Tong, Edward C., Pascale, Enzo, Bezawada, Naidu, Barstow, Joanna, Beaulieu, Jean-Philippe, Bowles, Neil, Coudé du Foresto, Vincent, Coustenis, Athena, Decin, Leen, Drossart, Pierre, Eccleston, Paul, Encrenaz, Therese, Forget, Francois, Griffin, Matt, Güdel, Manuel, Hartogh, Paul, Heske, Astrid, Lagage, Pierre-Olivier, Leconte, Jeremy, Malaguti, Pino, Micela, Giusi, Middleton, Kevin, Min, Michiel, Moneti, Andrea, Morales, Juan Carlos, Mugnai, Lorenzo, Ollivier, Marc, Pace, Emanuele, Papageorgiou, Andreas, Pilbratt, Goran, Puig, Ludovic, Rataj, Miroslaw, Ray, Tom, Ribas, Ignasi, Rocchetto, Marco, Sarkar, Subhajit, Selsis, Franck, Taylor, William, Tennyson, Jonathan, Tinetti, Giovanna, Turrini, Diego, Vandenbussche, Bart, Venot, Olivia, Waldmann, Ingo P., Wolkenberg, Paulina, Wright, Gillian, Zapatero Osorio, Maria-Rosa, and Zingales, Tiziano
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- 2018
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19. Morphological Associations between the Distal Radioulnar Joint and the Lunate
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Mauler, Flavien and Beaulieu, Jean-Yves
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- 2018
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20. Painful Flexor Carpi Radialis Brevis Muscle: An Ultrasound and Magnetic Resonance Imaging Assessment
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Urigo, Carlo, Schenkel, Marie Claude, Beaulieu, Jean‐Yves, and Bianchi, Stefano
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- 2017
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21. Accelerating the selection process for Populusand Salixclones using short-term photosynthetic acclimation responses under greenhouse conditions
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Mamashita, Takamitsu, Larocque, Guy R., DesRochers, Annie, Beaulieu, Jean, Thomas, Barb R., Mosseler, Alex, Major, John, and Sidders, Derek
- Abstract
ABSTRACTLeaf photosynthetic characteristics could be determinant factors to identify the most productive clones of hybrid poplars (Populusspp.) and willows (Salixspp.). Photosynthetic acclimation of hybrid poplars and willows was studied under greenhouse conditions. Seven Populusand five Salixclones were grown for 3 months at three spacings [20 × 20, 35 × 35, and 60 × 60 cm] and two nitrogen (N) levels (20 and 200 μg g−1). There were no significant spacing effects on leafless aboveground biomass per tree (AGBT) and height. Clonal acclimation to higher density was associated to increases in leaf area index (LAI) by 347% and specific leaf area (SLA) by 13% despite decreased leaf N content per unit leaf area (Narea) by 31%. There were no changes in net CO2assimilation rate (A) and photosynthetic N-use efficiency in the ambient light condition (PNUEamb) within different spacings. The N addition alleviated competition effects by maximizing leaf area (LA) and SLA. Compared with less productive clones, more productive clones had 28% greater SLA, greater LA and AGBT per unit of increase in Nareaover all treatments. The increased development of LA and SLA under high planting density is a key indicator of more productive clones.
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- 2017
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22. Recurrent carpal tunnel syndrome: Outcomes after neurolysis and synovial flap
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Bollmann, Guillaume, Bouvet, Cindy, and Beaulieu, Jean-Yves
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Objectifs: Les révisions chirurgicales après neurolyse primaire du nerf médian sont nécessaires en cas de récidive des symptômes. Soltani et al. (2013) ont démontré que les révisions chirurgicales avec interposition d’un lambeau vascularisé ont un taux de succès supérieur (86 %) aux révisions chirurgicales sans lambeau (75 %). L’objectif de cette étude est de présenter les résultats cliniques d’une série rétrospective incluant 36 neurolyses secondaires du nerf médian à ciel ouvert et lambeau synovial en cas de récidive de syndrome du canal carpien.
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- 2023
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23. Découverte de la première planète extrasolaire tellurique
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Beaulieu, Jean-Philippe, Cassan, Arnaud, Beaulieu, Jean-Philippe, and Cassan, Arnaud
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Pour détecter les planètes extrasolaires, l’utilisation du phénomène de microlentille gravitationnelle présente le grand avantage par rapport aux autres méthodes d’être la seule sensible aux planètes de faible masse situées à relativement grande distance de leur étoile – telle une Neptune ou une Terre en orbite à une dizaine d’unités astronomiques (UA). Nous présentons ici la découverte, grâce à cette technique, de la première planète tellurique, OGLE-2005BLG-390Lb, une cousine glacée de la Terre environ cinq fois plus massive, évoluant sur une orbite de 2,6 UA autour d’une étoile naine rouge.
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- 2008
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24. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
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Klionsky, Daniel J, Abdelmohsen, Kotb, Abe, Akihisa, Abedin, Md Joynal, Abeliovich, Hagai, Acevedo Arozena, Abraham, Adachi, Hiroaki, Adams, Christopher M, Adams, Peter D, Adeli, Khosrow, Adhihetty, Peter J, Adler, Sharon G, Agam, Galila, Agarwal, Rajesh, Aghi, Manish K, Agnello, Maria, Agostinis, Patrizia, Aguilar, Patricia V, Aguirre-Ghiso, Julio, Airoldi, Edoardo M, Ait-Si-Ali, Slimane, Akematsu, Takahiko, Akporiaye, Emmanuel T, Al-Rubeai, Mohamed, Albaiceta, Guillermo M, Albanese, Chris, Albani, Diego, Albert, Matthew L, Aldudo, Jesus, Algül, Hana, Alirezaei, Mehrdad, Alloza, Iraide, Almasan, Alexandru, Almonte-Beceril, Maylin, Alnemri, Emad S, Alonso, Covadonga, Altan-Bonnet, Nihal, Altieri, Dario C, Alvarez, Silvia, Alvarez-Erviti, Lydia, Alves, Sandro, Amadoro, Giuseppina, Amano, Atsuo, Amantini, Consuelo, Ambrosio, Santiago, Amelio, Ivano, Amer, Amal O, Amessou, Mohamed, Amon, Angelika, An, Zhenyi, Anania, Frank A, Andersen, Stig U, Andley, Usha P, Andreadi, Catherine K, Andrieu-Abadie, Nathalie, Anel, Alberto, Ann, David K, Anoopkumar-Dukie, Shailendra, Antonioli, Manuela, Aoki, Hiroshi, Apostolova, Nadezda, Aquila, Saveria, Aquilano, Katia, Araki, Koichi, Arama, Eli, Aranda, Agustin, Araya, Jun, Arcaro, Alexandre, Arias, Esperanza, Arimoto, Hirokazu, Ariosa, Aileen R, Armstrong, Jane L, Arnould, Thierry, Arsov, Ivica, Asanuma, Katsuhiko, Askanas, Valerie, Asselin, Eric, Atarashi, Ryuichiro, Atherton, Sally S, Atkin, Julie D, Attardi, Laura D, Auberger, Patrick, Auburger, Georg, Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Avantaggiati, Maria Laura, Avrahami, Limor, Awale, Suresh, Azad, Neelam, Bachetti, Tiziana, Backer, Jonathan M, Bae, Dong-Hun, Bae, Jae-sung, Bae, Ok-Nam, Bae, Soo Han, Baehrecke, Eric H, Baek, Seung-Hoon, Baghdiguian, Stephen, Bagniewska-Zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xue-Yuan, Bailly, Yannick, Balaji, Kithiganahalli Narayanaswamy, Balduini, Walter, Ballabio, Andrea, Balzan, Rena, Banerjee, Rajkumar, Bánhegyi, Gábor, Bao, Haijun, Barbeau, Benoit, Barrachina, Maria D, Barreiro, Esther, Bartel, Bonnie, Bartolomé, Alberto, Bassham, Diane C, Bassi, Maria Teresa, Bast, Robert C, Basu, Alakananda, Batista, Maria Teresa, Batoko, Henri, Battino, Maurizio, Bauckman, Kyle, Baumgarner, Bradley L, Bayer, K Ulrich, Beale, Rupert, Beaulieu, Jean-François, Beck, George R., Becker, Christoph, Beckham, J David, Bédard, Pierre-André, Bednarski, Patrick J, Begley, Thomas J, Behl, Christian, Behrends, Christian, Behrens, Georg MN, Behrns, Kevin E, Bejarano, Eloy, Belaid, Amine, Belleudi, Francesca, Bénard, Giovanni, Berchem, Guy, Bergamaschi, Daniele, Bergami, Matteo, Berkhout, Ben, Berliocchi, Laura, Bernard, Amélie, Bernard, Monique, Bernassola, Francesca, Bertolotti, Anne, Bess, Amanda S, Besteiro, Sébastien, Bettuzzi, Saverio, Bhalla, Savita, Bhattacharyya, Shalmoli, Bhutia, Sujit K, Biagosch, Caroline, Bianchi, Michele Wolfe, Biard-Piechaczyk, Martine, Billes, Viktor, Bincoletto, Claudia, Bingol, Baris, Bird, Sara W, Bitoun, Marc, Bjedov, Ivana, Blackstone, Craig, Blanc, Lionel, Blanco, Guillermo A, Blomhoff, Heidi Kiil, Boada-Romero, Emilio, Böckler, Stefan, Boes, Marianne, Boesze-Battaglia, Kathleen, Boise, Lawrence H, Bolino, Alessandra, Boman, Andrea, Bonaldo, Paolo, Bordi, Matteo, Bosch, Jürgen, Botana, Luis M, Botti, Joelle, Bou, German, Bouché, Marina, Bouchecareilh, Marion, Boucher, Marie-Josée, Boulton, Michael E, Bouret, Sebastien G, Boya, Patricia, Boyer-Guittaut, Michaël, Bozhkov, Peter V, Brady, Nathan, Braga, Vania MM, Brancolini, Claudio, Braus, Gerhard H, Bravo-San Pedro, José M, Brennan, Lisa A, Bresnick, Emery H, Brest, Patrick, Bridges, Dave, Bringer, Marie-Agnès, Brini, Marisa, Brito, Glauber C, Brodin, Bertha, Brookes, Paul S, Brown, Eric J, Brown, Karen, Broxmeyer, Hal E, Bruhat, Alain, Brum, Patricia Chakur, Brumell, John H, Brunetti-Pierri, Nicola, Bryson-Richardson, Robert J, Buch, Shilpa, Buchan, Alastair M, Budak, Hikmet, Bulavin, Dmitry V, Bultman, Scott J, Bultynck, Geert, Bumbasirevic, Vladimir, Burelle, Yan, Burke, Robert E, Burmeister, Margit, Bütikofer, Peter, Caberlotto, Laura, Cadwell, Ken, Cahova, Monika, Cai, Dongsheng, Cai, Jingjing, Cai, Qian, Calatayud, Sara, Camougrand, Nadine, Campanella, Michelangelo, Campbell, Grant R, Campbell, Matthew, Campello, Silvia, Candau, Robin, Caniggia, Isabella, Cantoni, Lavinia, Cao, Lizhi, Caplan, Allan B, Caraglia, Michele, Cardinali, Claudio, Cardoso, Sandra Morais, Carew, Jennifer S, Carleton, Laura A, Carlin, Cathleen R, Carloni, Silvia, Carlsson, Sven R, Carmona-Gutierrez, Didac, Carneiro, Leticia AM, Carnevali, Oliana, Carra, Serena, Carrier, Alice, Carroll, Bernadette, Casas, Caty, Casas, Josefina, Cassinelli, Giuliana, Castets, Perrine, Castro-Obregon, Susana, Cavallini, Gabriella, Ceccherini, Isabella, Cecconi, Francesco, Cederbaum, Arthur I, Ceña, Valentín, Cenci, Simone, Cerella, Claudia, Cervia, Davide, Cetrullo, Silvia, Chaachouay, Hassan, Chae, Han-Jung, Chagin, Andrei 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von Haefen, Clarissa, von Schwarzenberg, Karin, Voth, Daniel E, Vouret-Craviari, Valérie, Vuori, Kristina, Vyas, Jatin M, Waeber, Christian, Walker, Cheryl Lyn, Walker, Mark J, Walter, Jochen, Wan, Lei, Wan, Xiangbo, Wang, Bo, Wang, Caihong, Wang, Chao-Yung, Wang, Chengshu, Wang, Chenran, Wang, Chuangui, Wang, Dong, Wang, Fen, Wang, Fuxin, Wang, Guanghui, Wang, Hai-jie, Wang, Haichao, Wang, Hong-Gang, Wang, Hongmin, Wang, Horng-Dar, Wang, Jing, Wang, Junjun, Wang, Mei, Wang, Mei-Qing, Wang, Pei-Yu, Wang, Peng, Wang, Richard C, Wang, Shuo, Wang, Ting-Fang, Wang, Xian, Wang, Xiao-jia, Wang, Xiao-Wei, Wang, Xin, Wang, Xuejun, Wang, Yan, Wang, Yanming, Wang, Ying, Wang, Ying-Jan, Wang, Yipeng, Wang, Yu, Wang, Yu Tian, Wang, Yuqing, Wang, Zhi-Nong, Wappner, Pablo, Ward, Carl, Ward, Diane McVey, Warnes, Gary, Watada, Hirotaka, Watanabe, Yoshihisa, Watase, Kei, Weaver, Timothy E, Weekes, Colin D, Wei, Jiwu, Weide, Thomas, Weihl, Conrad C, Weindl, Günther, Weis, Simone Nardin, Wen, Longping, Wen, Xin, Wen, Yunfei, Westermann, Benedikt, Weyand, Cornelia M, White, Anthony R, White, Eileen, Whitton, J Lindsay, Whitworth, Alexander J, Wiels, Joëlle, Wild, Franziska, Wildenberg, Manon E, Wileman, Tom, Wilkinson, Deepti Srinivas, Wilkinson, Simon, Willbold, Dieter, Williams, Chris, Williams, Katherine, Williamson, Peter R, Winklhofer, Konstanze F, Witkin, Steven S, Wohlgemuth, Stephanie E, Wollert, Thomas, Wolvetang, Ernst J, Wong, Esther, Wong, G William, Wong, Richard W, Wong, Vincent Kam Wai, Woodcock, Elizabeth A, Wright, Karen L, Wu, Chunlai, Wu, Defeng, Wu, Gen Sheng, Wu, Jian, Wu, Junfang, Wu, Mian, Wu, Min, Wu, Shengzhou, Wu, William KK, Wu, Yaohua, Wu, Zhenlong, Xavier, Cristina PR, Xavier, Ramnik J, Xia, Gui-Xian, Xia, Tian, Xia, Weiliang, Xia, Yong, Xiao, Hengyi, Xiao, Jian, Xiao, Shi, Xiao, Wuhan, Xie, Chuan-Ming, Xie, Zhiping, Xie, Zhonglin, Xilouri, Maria, Xiong, Yuyan, Xu, Chuanshan, Xu, Congfeng, Xu, Feng, Xu, Haoxing, Xu, Hongwei, Xu, Jian, Xu, Jianzhen, Xu, Jinxian, Xu, Liang, Xu, Xiaolei, Xu, Yangqing, Xu, Ye, Xu, Zhi-Xiang, Xu, Ziheng, Xue, Yu, Yamada, Takahiro, Yamamoto, Ai, Yamanaka, Koji, Yamashina, Shunhei, Yamashiro, Shigeko, Yan, Bing, Yan, Bo, Yan, Xianghua, Yan, Zhen, Yanagi, Yasuo, Yang, Dun-Sheng, Yang, Jin-Ming, Yang, Liu, Yang, Minghua, Yang, Pei-Ming, Yang, Peixin, Yang, Qian, Yang, Wannian, Yang, Wei Yuan, Yang, Xuesong, Yang, Yi, Yang, Ying, Yang, Zhifen, Yang, Zhihong, Yao, Meng-Chao, Yao, Pamela J, Yao, Xiaofeng, Yao, Zhenyu, Yao, Zhiyuan, Yasui, Linda S, Ye, Mingxiang, Yedvobnick, Barry, Yeganeh, Behzad, Yeh, Elizabeth S, Yeyati, Patricia L, Yi, Fan, Yi, Long, Yin, Xiao-Ming, Yip, Calvin K, Yoo, Yeong-Min, Yoo, Young Hyun, Yoon, Seung-Yong, Yoshida, Ken-Ichi, Yoshimori, Tamotsu, Young, Ken H, Yu, Huixin, Yu, Jane J, Yu, Jin-Tai, Yu, Jun, Yu, Li, Yu, W Haung, Yu, Xiao-Fang, Yu, Zhengping, Yuan, Junying, Yuan, Zhi-Min, Yue, Beatrice YJT, Yue, Jianbo, Yue, Zhenyu, Zacks, David N, Zacksenhaus, Eldad, Zaffaroni, Nadia, Zaglia, Tania, Zakeri, Zahra, Zecchini, Vincent, Zeng, Jinsheng, Zeng, Min, Zeng, Qi, Zervos, Antonis S, Zhang, Donna D, Zhang, Fan, Zhang, Guo, Zhang, Guo-Chang, Zhang, Hao, Zhang, Hong, Zhang, Hong, Zhang, Hongbing, Zhang, Jian, Zhang, Jian, Zhang, Jiangwei, Zhang, Jianhua, Zhang, Jing-pu, Zhang, Li, Zhang, Lin, Zhang, Lin, Zhang, Long, Zhang, Ming-Yong, Zhang, Xiangnan, Zhang, Xu Dong, Zhang, Yan, Zhang, Yang, Zhang, Yanjin, Zhang, Yingmei, Zhang, Yunjiao, Zhao, Mei, Zhao, Wei-Li, Zhao, Xiaonan, Zhao, Yan G, Zhao, Ying, Zhao, Yongchao, Zhao, Yu-xia, Zhao, Zhendong, Zhao, Zhizhuang J, Zheng, Dexian, Zheng, Xi-Long, Zheng, Xiaoxiang, Zhivotovsky, Boris, Zhong, Qing, Zhou, Guang-Zhou, Zhou, Guofei, Zhou, Huiping, Zhou, Shu-Feng, Zhou, Xu-jie, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-Guo, Zhu, Wenhua, Zhu, Xiao-Feng, Zhu, Yuhua, Zhuang, Shi-Mei, Zhuang, Xiaohong, Ziparo, Elio, Zois, Christos E, Zoladek, Teresa, Zong, Wei-Xing, Zorzano, Antonio, and Zughaier, Susu M
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- 2016
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25. L'écriture féminine à la Renaissance française sous le regard des chercheurs canadiens.
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DESROSIERS, DIANE and BEAULIEU, JEAN-PHILIPPE
- Subjects
WOMEN authors ,RENAISSANCE literature ,CANADIANS ,LITERARY historians ,16TH century French literature ,17TH century French literature ,RHETORIC education ,16TH century French history ,17TH century French history ,FRENCH literature ,LITERARY criticism - Abstract
Copyright of Renaissance & Reformation / Renaissance et Réforme is the property of Iter Canada and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
26. AIRS: ARIEL IR spectrometer status
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Coyle, Laura E., Matsuura, Shuji, Perrin, Marshall D., Martignac, Jérôme, Amiaux, Jérôme, Berthé, Michel, Cara, Christophe, Delisles, Cyrille, Direk, Achrène, Dumaye, Luc, Fontignie, Jean, Goestschy, Alain, Horeau, Benoît, Hurtado, Norma, Huyn, Duc-Dat, Kaszubiak, Grégory, Lagage, Pierre-Olivier, Le Mer, Isabelle, Lortholary, Michel, Moreau, Vincent, Mouzali, Salima, Mulet, Patrick, Nico, François, Pichon, Thibault, Provost, Lena, Renaud, Diana, Schwartz, Victor, Talvard, Michel, Tourrette, Thierry, Visticot, François, Arhancet, Axel, Bachet, Damien, Berton, Nicolas, Lacroix, Mickael, Le Provost, Hervé, Tellier, Olivier, Philippon, Anne, De Jabrun, Clémence, Dubois, Jean-Pierre, Langlet, François, Le Claire, Dylan, Lecomte, Benoît, Ollivier, Marc, Tosti, Stéphane, Lapeyrère, Vincent, Bonafous, Marion, Parisot, Jérôme, Reess, Jean-Michel, Zegadanin, Didier, Beaulieu, Jean-Philipe, Batista, Virginie, Drossart, Pierre, Fahmy, Salma, Jollet, Delphine, Puig, Ludovic, Tirolien, Thierry, Danto, Pascale, Hervet, Gilles, Maisonnave, Oceane, Eccleston, Paul, Bishop, Georgia, Drumond, Rachel, Caldwell, Andrew, Caldwell, Martin, Desjonqueres, Lucile, Whalley, Martin, Pascale, Enzo, Morgante, Gianluca, Focardi, Mauro, Pace, Emanuele, and Di Giorgio, Anna Maria
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- 2022
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27. Septic Tenosynovitis of the Hand: Factors Predicting Need for Subsequent Débridement
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Müller, Camillo T., Uçkay, Ilker, Erba, Paolo, Lipsky, Benjamin A., Hoffmeyer, Pierre, and Beaulieu, Jean-Yves
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- 2015
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28. PREDICTION OF TRACHEID LENGTH AND DIAMETER IN WHITE SPRUCE (PICEA GLAUCA)
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Mvolo, Cyriac S., Koubaa, Ahmed, Defo, Maurice, Beaulieu, Jean, Yemele, Martin-Claude, and Cloutier, Alain
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- 2015
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29. Variation in stem morphology and movement of amyloplasts in white spruce grown in the weightless environment of the International Space Station
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Rioux, Danny, Lagacé, Marie, Cohen, Luchino Y., and Beaulieu, Jean
- Abstract
One-year-old white spruce (Picea glauca) seedlings were studied in microgravity conditions in the International Space Station (ISS) and compared with seedlings grown on Earth. Leaf growth was clearly stimulated in space whereas data suggest a similar trend for the shoots. Needles on the current shoots of ground-based seedlings were more inclined towards the stem base than those of seedlings grown in the ISS. Amyloplasts sedimented in specialized cells of shoots and roots in seedlings grown on Earth while they were distributed at random in similar cells of seedlings tested in the ISS. In shoots, such amyloplasts were found in starch sheath cells located between leaf traces and cortical cells whereas in roots they were constituents of columella cells of the cap. Nuclei were regularly observed just above the sedimented amyloplasts in both organs. It was also frequent to detect vacuoles with phenolic compounds and endoplasmic reticulum (ER) close to the sedimented amyloplasts. The ER was mainly observed just under these amyloplasts. Thus, when amyloplasts sediment, the pressure exerted on the ER, the organelle that can for instance secrete proteins destined for the plasma membrane, might influence their functioning and play a role in signaling pathways involved in gravity-sensing white spruce cells.
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- 2015
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30. « Moy Traductrice » : le façonnement de la figure auctoriale dans le paratexte des traductions de Marie de Gournay.
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BEAULIEU, JEAN-PHILIPPE
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PARATEXT ,DEDICATIONS ,TRANSLATIONS of Latin literature ,TRANSLATORS ,HISTORY - Abstract
Marie Le Jars de Gournay's prolific textual production has attracted increasing scholarly attention in the last few years. One of the still relatively understudied parts of her oeuvre comprises the five translations from Latin that occupy 274 out of the 995 pages of her 1641 Advis. As Montaigne's "fille d'alliance", she seems to be mainly known for her French versions of the Latin quotations in the Essais; however, her own translations from Ovid's Elegies or Virgil's Aeneid have been largely overlooked, as well as the liminary writings--some of which prove quite substantial, as her De la façon d'escrire de Messieurs l'eminentissime Cardinal du Perron et Bertaut--where Gournay offers her remarks on the art of translation. In this essay, I wish to focus on these paratextual writings to examine the self-defining strategies employed by Marie de Gournay in order to legitimize her translation activities. Faced with the obstacles caused by "the little credit given to [her] sex", as well as the specific challenges posed by her sources, Gournay interestingly presents her work as composed in "such an unscholarly season" ("une saison sipeu studieuse"), that is at a time when the humanist ideals of the sixteenth century were no longer valued. This article seeks to attend to the ethos constructed through the dedications and other liminary pieces in the second book of the Advis, and to examine how Gournay's discursive ethos serves to anticipate and guide the reception of her translations. In this context, paratexts should be viewed, not as mere accessories, but rather as an essential discursive framework for the interpretation of Gournay's translations--it is actually quite clear from the arrangement of the volume that the liminary material was designed as a tight interpretive frame for the translated texts. This study will eventually allow us to determine the place of translation within the range of authorial practices embraced by Marie de Gournay. [ABSTRACT FROM AUTHOR]
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- 2012
31. The implementation of assisted migration in Canadian forests.
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Pedlar, John H., McKenney, Daniel W., Beaulieu, Jean, Colombo, Stephen J., McLachlan, Jason S., and O'Neill, Gregory A.
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ASSISTED migration (Plant colonization) ,PLANT species ,FOREST policy ,FOREST management ,FORESTS & forestry - Abstract
Copyright of Forestry Chronicle is the property of Canadian Institute of Forestry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2011
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- View/download PDF
32. Juvenile productivity of five hybrid poplar clones and 20 genetically improved white and Norway spruces in boreal clay-belt of Quebec, Canada. .
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LarchevÊque, Marie, Larocque, Guy R., Desrochers, Annie, Tremblay, Francine, Gaussiran, Stéphane, Boutin, Robert, Brais, Suzanne, Beaulieu, Jean, Daoust, Gaétan, and Périnet, Pierre
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PLANT competition ,POPLARS ,WHITE spruce ,NORWAY spruce ,PLANT species ,FIELD research - Abstract
Copyright of Forestry Chronicle is the property of Canadian Institute of Forestry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2010
33. Benefits of using genetically improved white spruce in Quebec: The forest landowner's viewpoint.
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Petrinovic, Juan Fernando, Gélinas, Nancy, and Beaulieu, Jean
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WHITE spruce ,PLANT fibers ,FOREST ecology ,SUSTAINABILITY ,SILVICULTURAL systems ,PLANT genetic engineering ,FOREST management - Abstract
Copyright of Forestry Chronicle is the property of Canadian Institute of Forestry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2009
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- View/download PDF
34. Rentabilité des plantations d'épinette blanche améliorée génétiquement au Québec : le point vue du propriétaire.
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Petrinovic, Juan Fernando, Gélinas, Nancy, and Beaulieu, Jean
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WHITE spruce ,PLANT fibers ,FOREST ecology ,SUSTAINABILITY ,SILVICULTURAL systems ,FOREST management ,PLANT genetic engineering - Abstract
Copyright of Forestry Chronicle is the property of Canadian Institute of Forestry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2009
- Full Text
- View/download PDF
35. Degeneration of the Pericryptal Myofibroblast Sheath by Proinflammatory Cytokines in Inflammatory Bowel Diseases.
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Francoeur, Caroline, Bouatrouss, Yamina, Seltana, Amira, Pinchuk, Iryna V., Vachon, Pierre H., Powell, Don W., Sawan, Basem, Seidman, Ernest G., and Beaulieu, Jean–François
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INFLAMMATORY bowel diseases ,MYOFIBROBLASTS ,CYTOKINES ,INTESTINAL mucosa ,MYELIN sheath ,IMMUNOHISTOCHEMISTRY ,INTERLEUKINS ,TRANSFORMING growth factors - Abstract
Background & Aims: Inflammatory bowel diseases (IBDs) are characterized by remodeling of the intestinal mucosa, which is associated with excessive cytokine release. Previous studies have shown that the epithelium in the crypt region of the mucosa in patients with Crohn''s disease is susceptible to proinflammatory cytokines. We investigated whether the subepithelial myofibroblasts in this region were affected by these inflammatory conditions. Methods: Immunofluorescence and immunohistochemistry were performed on inflamed and uninflamed specimens from patients with IBD to detect α-smooth muscle actin (αSMA), desmin, and tenascin-C. The effects of the proinflammatory cytokines interleukin-1β, tumor necrosis factor-α, and interferon-γ were analyzed in human intestinal myofibroblast cultures by immunoblotting and apoptosis assays. Results: Immunofluorescence analysis revealed decreased levels of the extracellular matrix molecule tenascin-C in pericryptal sheaths and αSMA in the immediate vicinity of the crypts in the inflamed specimens, indicating that the myofibroblast pericryptal sheath is affected by proinflammatory cytokines. Although individual cytokines did not affect myofibroblast proliferation or survival, cytokine combinations triggered caspase-dependent apoptosis. αSMA levels were reduced significantly in cells exposed to cytokines, either alone or in combination, suggesting dedifferentiation of myofibroblasts. Proinflammatory cytokines did not affect tenascin-C expression, suggesting that the decrease observed in the inflamed mucosa resulted from myofibroblast apoptosis. Conclusions: The subepithelial myofibroblasts of the epithelial sheath are disrupted in the intestinal mucosa of patients with IBD. A loss of myofibroblasts appears to result from the susceptibility of these cells to proinflammatory cytokines. [Copyright &y& Elsevier]
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- 2009
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36. Implication of TNF-Related Apoptosis-Inducing Ligand in Inflammatory Intestinal Epithelial Lesions.
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Begue, Bernadette, Wajant, Harald, Bambou, Jean–Christophe, Dubuquoy, Laurent, Siegmund, Daniela, Beaulieu, Jean–François, Canioni, Danielle, Berrebi, Dominique, Brousse, Nicole, Desreumaux, Pierre, Schmitz, Jacques, Lentze, Michael J., Goulet, Oliver, Cerf–Bensussan, Nadine, and Ruemmele, Frank M.
- Subjects
APOPTOSIS ,TUMOR necrosis factors ,INFLAMMATORY bowel diseases ,EPITHELIUM - Abstract
Background & Aims: Few data exist on the molecular events causing intestinal epithelial destruction during inflammatory processes, such as inflammatory bowel disease (IBD). In this work, we analyzed the potential implication of tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) in these inflammatory lesions. Methods: TRAIL and TRAIL-receptor expression were analyzed in normal, inflammatory ileum/colon and human intestinal epithelial cell (IEC) lines (HIEC), Caco-2, and HT-29 using RNase protection assay, real-time and reverse-transcription polymerase chain reaction (RT-PCR), immunohistochemistry, and Western blot analysis. TRAIL-induced activation of NF-κB was determined by electrophoretic mobility shift assay. Caspase-recruitment domain (CARD)15 expression and interleukin-(IL)8 production were studied by RT-PCR and enzyme-linked immunosorbent assay. Apoptosis was monitored using Annexin-V/caspase-3 assays. Results: Normal mature IEC expressed low TRAIL levels, whereas, in inflammatory lesions, TRAIL messenger RNA and protein were markedly up-regulated in IEC and lamina propria lymphocytes at levels comparable with trinitrobenzene sulfonic acid-induced colitis. Interferon-γ and TNF-α potently induced TRAIL in IEC. In vitro analyses revealed a dual biologic effect of TRAIL on HIEC: Under noninflammatory conditions, TRAIL up-regulated via nuclear factor-κB CARD15 and IL-8, whereas, under inflammatory conditions, TRAIL became a potent inducer of apoptosis in HIEC, which was confirmed ex vivo using ileal organ cultures. TNF-α markedly increased the expression of the proapoptotic receptor TRAIL-R2. TRAIL-induced IEC apoptosis required a functional caspase cascade. Conclusions: TRAIL is a new inflammatory mediator implicated in the homeostasis of intestinal epithelial barrier functions. TRAIL is highly up-regulated in IEC in inflammatory ileum and colon. It may augment in an auto-/paracrine fashion the elimination of IEC via apoptosis. [Copyright &y& Elsevier]
- Published
- 2006
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37. Adaptation to climate change: Genetic variation is both a short- and a long-term solution.
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Beaulieu, Jean and Rainville, André
- Subjects
CLIMATE change ,BUSINESS relocation ,PINACEAE ,GLOBAL warming ,GREENHOUSE effect ,FORESTS & forestry - Abstract
Copyright of Forestry Chronicle is the property of Canadian Institute of Forestry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2005
- Full Text
- View/download PDF
38. The impact of climate change on growth of local white spruce populations in Québec, Canada.
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Andalo, Christophe, Beaulieu, Jean, and Bousquet, Jean
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CLIMATE change ,WHITE spruce ,PINACEAE - Abstract
Abstract: In the near future, forest tree species growing in eastern Canada are expected to be affected by climate change due to an increase of human-induced greenhouse gas emissions. In this study, models were developed to estimate the impact of climate change on growth in white spruce (Picea glauca (Moench) Voss). Data were collected in a genecological test, replicated in three locations, and involving 45 distinct geographical seed sources, most of them represented by five open-pollinated families. Transfer models predicting the performance of seed sources were developed, based on temperature and precipitation differentials between the geographical origin of seed sources and the experimental site locations. These models were validated using data collected in a second genecological test series. We found that white spruce populations located within the sampled area were optimally adapted to their local environment for thermal conditions but not for moisture conditions; populations that originated from sites receiving more precipitation generally showed higher tree growth than the local sources. We predict that the adaptive lag currently related to precipitation will increase under global warming conditions. Simulations of growth under various scenarios of climate change indicated that it would be diminished tangibly under more intense warming. However, for a given temperature increase, the relative loss in growth will be less if precipitation is reduced than if it increases. Consequently, predictions based solely on temperature change appear inaccurate, and more effort should be directed toward better anticipating the magnitude and the direction of changes in precipitation patterns at the regional scale. The necessity of human intervention to assist tree migration under climate change is examined. [Copyright &y& Elsevier]
- Published
- 2005
- Full Text
- View/download PDF
39. Design and performance of the Exo-planet Characterisation Observatory (EChO) integrated payload
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Oschmann, Jacobus M., Clampin, Mark, Fazio, Giovanni G., MacEwen, Howard A., Swinyard, Bruce, Tessenyi, Marcel, Tinetti, Giovanna, Waldmann, Ingo, Eccleston, Paul, Ferlet, Marc, Irshad, Ranah, Lim, Tanya, Middleton, Kevin, Bradshaw, Tom, Crook, Martin, Hunt, Tom, Winter, Berend, Bryson, Ian, Bezawada, Naidu, Taylor, William, Bowles, Neil, Pascale, Enzo, Morgante, Gianluca, Pace, Emanuele, Adriani, Alberto, Reess, Jean-Michel, Drossart, Pierre, Coudé du Foresto, Vincent, Ollivier, Marc, Ottensamer, Roland, Rataj, Mirek, Ramos Zapata, Gonzalo, Schrader, Jan-Rutger, Selig, Avri, Isaak, Kate, Linder, Martin, Puig, Ludovic, Hartogh, Paul, Lovis, Christophe, Micela, Giusi, Ribas, Ignasi, Snellen, Ignas, and Beaulieu, Jean-Phillippe
- Published
- 2014
- Full Text
- View/download PDF
40. Control of the Human Osteopontin Promoter by ERRα in Colorectal Cancer
- Author
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Boudjadi, Salah, Bernatchez, Gérald, Beaulieu, Jean-François, and Carrier, Julie C.
- Abstract
Colorectal cancer is the second leading cause of death from cancer. Osteopontin (OPN) is a component of tumor extracellular matrix identified as a key marker of cancer progression. The estrogen-related receptor α (ERRα) has been implicated in endocrine-related cancer development and progression, possibly through modulation of cellular energy metabolism. Previous reports that ERRα regulates OPN expression in bone prompted us to investigate whether ERRα controls OPN expression in human colorectal cancer. Using a tissue microarray containing 83 tumor-normal tissue pairs of colorectal cancer samples, we found that tumor epithelial cells displayed higher staining for ERRα than normal mucosa, in correlation with elevated OPN expression. In addition, knocking down endogenous ERRα led to reduced OPN expression in HT29 colon cancer cells. Promoter analysis, inhibition of ERRα activity, and expression and mutation of potential ERRα response elements in the proximal promoter of human OPN showed that ERRα and its obligate co-activator, peroxisome proliferator-activated receptor γ co-activator-1 α, positively control human OPN promoter activity. Furthermore, chromatin immunoprecipitation experiments confirmed in vivooccupancy of the OPN promoter by ERRα in HT29 cells, suggesting that OPN is a direct target of ERRα in colorectal cancer. These findings suggest an additional mechanism by which ERRα participates in the development and progression of colorectal cancer, further supporting the relevance of targeting ERRα with antagonists as anticancer agents.
- Published
- 2013
- Full Text
- View/download PDF
41. Genetic parameters and clonal variation in growth and nutritional traits of containerized white spruce somatic seedlings
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Wahid, Nadya, Lamhamedi, Mohammed S., Beaulieu, Jean, Margolis, HankA., and Deblois, Josianne
- Abstract
AbstractClonal forestry can significantly increase forest productivity and its establishment requires a high level of clonal variation to maximize genetic gain and diversity. An evaluation of the genetic parameters of clones at a juvenile stage is necessary to better understand the amplitude of clonal variability and the degree of genetic control. The analysis of variance of white spruce clones showed a highly significant clonal effect for the majority of the growth characters at the end of both growing seasons and for the mineral status at the 2+0 stage. Our results reveal that height exhibits a high clonal heritability value which remained stable over the two growing seasons (H2c= 0.60). Strong genotypic and phenotypic correlations were observed between height and diameter at the end of the first growing season and between height and the rest of the growth characters at the end of the second growing season. The strong clonal variation, genetic control and genetic correlation particularly of height found in this study indicate that the selection ability of the best performing clones is possible for intensive forest management.
- Published
- 2012
- Full Text
- View/download PDF
42. Autophagy is active in normal colon mucosa
- Author
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Groulx, Jean-Francois, Khalfaoui, Taoufik, Benoit, Yannick D., Bernatchez, Gérald, Carrier, Julie C., Basora, Nuria, and Beaulieu, Jean-François
- Abstract
Recently, autophagy has been found to be strongly activated in colon cancer cells, but few studies have addressed the normal colon mucosa. The aim of this study was to characterize autophagy in normal human intestinal cells. We used the expression of LC3-II and BECN1 as well as SQSTM1 as markers of autophagy activity. Using the normal human intestinal epithelial crypt (HIEC) cell experimental model, we found that autophagy was much more active in undifferentiated cells than in differentiated cells. In the normal adult colonic mucosa, BECN1 was found in the proliferative epithelial cells of the lower part of the gland while SQSTM1 was predominantly found in the differentiated cells of the upper part of the gland and surface epithelium. Interestingly, the weak punctate pattern of SQSTM1 expression in the lower gland colocalized with BECN1-labeled autophagosomes. The usefulness of SQSTM1 as an active autophagy marker was confirmed in colon cancer specimens at the protein and transcript levels. In conclusion, our results show that autophagy is active in the colonic gland and is associated with the intestinal proliferative/undifferentiated and progenitor cell populations.
- Published
- 2012
- Full Text
- View/download PDF
43. Range-wide chloroplast and mitochondrial DNA imprints reveal multiple lineages and complex biogeographic history for Douglas-fir
- Author
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Wei, Xiao-Xin, Beaulieu, Jean, Khasa, Damase, Vargas-Hernández, Jesús, López-Upton, Javier, Jaquish, Barry, and Bousquet, Jean
- Abstract
Abstract: The contemporary genetic structure of species offers key imprints of how organisms responded to past geological and climatic events, which have played a crucial role in shaping the current geographical distribution of north-temperate organisms. In this study, range-wide patterns of genetic variation were examined in Douglas-fir (Pseudotsuga menziesii), a dominant forest tree species distributed from Mexico to British Columbia in western North America. Two organelle DNA markers with contrasting modes of inheritance were genotyped for 613 individuals from 44 populations. Two mitotypes and 42 chlorotypes were recovered in this survey. Both genomes showed significant population subdivision, indicative of limited gene flow through seeds and pollen. Three distinct cpDNA lineages corresponding to the Pacific Coast, the Rocky Mountains, and Mexico were observed. The split time of the two lineages from the Rockies lineage was dated back to 8.5 million years (Ma). The most recent common ancestors of Mexican and coastal populations were estimated at 3.2 and 4.8 Ma, respectively. The northern populations of once glaciated regions were characterized by a high level of genetic diversity, indicating a large zone of contact between ancestral lineages. A possible northern refugium was also inferred. The Mexican lineage, which appeared established by southward migration from the Rockies lineage, was characterized by the lowest genetic diversity but highest population differentiation. These results suggest that the effects of Quaternary climatic oscillations on the population dynamics and genetic diversity of Douglas-fir varied substantially across the latitudinal section. The results emphasize the pressing need for the conservation of Mexican Douglas-fir.
- Published
- 2011
- Full Text
- View/download PDF
44. The exoplanet microlensing survey by the proposed WFIRST Observatory
- Author
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Barry, Richard, Kruk, Jeffery, Anderson, Jay, Beaulieu, Jean-Philippe, Bennett, David P., Catanzarite, Joseph, Cheng, Ed, Gaudi, Scott, Gehrels, Neil, Kane, Stephen, Lunine, Jonathan, Sumi, Takahiro, Tanner, Angelle, and Traub, Wesley
- Abstract
The New Worlds, New Horizons report released by the Astronomy and Astrophysics Decadal Survey Board in 2010 listed the Wide Field Infrared Survey Telescope (WFIRST) as the highest-priority large space mission for the coming decade. This observatory will provide wide-field imaging and slitless spectroscopy at near infrared wavelengths. The scientific goals are to obtain a statistical census of exoplanets using gravitational microlensing, measure the expansion history of and the growth of structure in the Universe by multiple methods, and perform other astronomical surveys to be selected through a guest observer program. A Science Definition Team has been established to assist NASA in the development of a Design Reference Mission that accomplishes this diverse array of science programs with a single observatory. In this paper we present the current WFIRST payload concept and the expected capabilities for planet detection. The observatory, with science goals that are complimentary to the Kepler exoplanet transit mission, is designed to complete the statistical census of planetary systems in the Galaxy, from habitable Earth-mass planets to free floating planets, including analogs to all of the planets in our Solar System except Mercury. The exoplanet microlensing survey will observe for 500 days spanning 5 years. This long temporal baseline will enable the determination of the masses for most detected exoplanets down to 0.1 Earth masses.
- Published
- 2011
- Full Text
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45. Gene-expression Profile Analysis in the Mid-gestation Human Intestine Discloses Greater Functional Immaturity of the Colon as Compared With the Ileum
- Author
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Tremblay, Eric, Ferretti, Emanuela, Babakissa, Corentin, Seidman, Ernest G, Levy, Emile, Ménard, Daniel, and Beaulieu, Jean-François
- Abstract
The occurrence of many neonatal inflammatory intestinal diseases in preterm infants highlights the susceptibility of the immature intestine to responding inadequately to nutrients and microbes. A better understanding of functional intestinal development is essential for the design of optimal treatments ensuring survival and growth of premature infants. The purpose of this study was to evaluate the gene expression profiles of the human ileum and colon at mid-gestation because these 2 segments are considered to be similar at this stage and are the sites of the most frequent pathologies in preterm infants.
- Published
- 2011
46. The influence of cambial age on breeding for wood properties in Picea glauca
- Author
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Lenz, Patrick, MacKay, John, Rainville, André, Cloutier, Alain, and Beaulieu, Jean
- Abstract
Abstract: We investigated the influence of cambial age on correlations between different wood traits and the possibility of early selection in order to help decision-making for the improvement of juvenile wood in white spruce (Picea glauca (Moench) Voss). Increment cores were analysed from 375 trees covering 25 open-pollinated families from a 30-year-old provenance–progeny trial in Quebec, Canada. Genetic and phenotypic correlations between different mechanical and fibre anatomy-related wood traits were found to vary with cambial age. Most correlations became stronger in magnitude in rings closer to the bark. An exception is the correlation between microfibril angle (MFA) and the modulus of elasticity where correlations were strongly negative from the pith to the bark. Age–age correlations for different wood traits were found to be high and possible gains from early selection were estimated to be good in ring 8 and older for most traits. MFA was the trait with the strongest potential for selection as early as ring 4, but a detrimental correlation with wood density may represent a drawback of such a juvenile selection approach. Estimates showed that selection concentrated on a few easily measurable traits such as wood density and core length holds promise to obtain superior genetic gains for mechanical properties, but negative impacts would be expected on fibre anatomy traits related to pulp quality. These findings show the need for more carefully planned breeding and selection strategies if one wishes to improve several traits for different end uses.
- Published
- 2011
- Full Text
- View/download PDF
47. Gene-expression Profile Analysis in the Mid-gestation Human Intestine Discloses Greater Functional Immaturity of the Colon as Compared With the Ileum
- Author
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Tremblay, Eric, Ferretti, Emanuela, Babakissa, Corentin, Seidman, Ernest G, Levy, Emile, Ménard, Daniel, and Beaulieu, Jean-François
- Abstract
The occurrence of many neonatal inflammatory intestinal diseases in preterm infants highlights the susceptibility of the immature intestine to responding inadequately to nutrients and microbes. A better understanding of functional intestinal development is essential for the design of optimal treatments ensuring survival and growth of premature infants. The purpose of this study was to evaluate the gene expression profiles of the human ileum and colon at mid-gestation because these 2 segments are considered to be similar at this stage and are the sites of the most frequent pathologies in preterm infants. We compared the gene-expression profiles of human fetal small and large intestines using a cDNA microarray and analyzed the data with Ingenuity Pathway Analysis software. We found that a significant proportion of the genes was differentially expressed in the 2 segments. Gene cluster analysis revealed an even higher level of transcriptional dissimilarity at the functional level. For instance, segment-specific/overexpressed gene clusters in the ileum included genes involved with amino acid, vitamin, and mineral metabolism, reflecting the higher level of maturity of the small intestine as compared with the colon in which genes involved with cell cycle, cell death, and cell signaling were the predominant clusters of genes expressed. Functional clustering analysis of the differentially expressed genes revealed important functional differences between the 2 segments and a relative immaturity of the colon, suggesting that already at mid-gestation, the 2 intestinal segments should be considered as 2 distinct organs.
- Published
- 2011
- Full Text
- View/download PDF
48. The Physiology, Signaling, and Pharmacology of Dopamine Receptors
- Author
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Beaulieu, Jean-Martin and Gainetdinov, Raul R.
- Abstract
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from voluntary movement and reward to hormonal regulation and hypertension. Pharmacological agents targeting dopaminergic neurotransmission have been clinically used in the management of several neurological and psychiatric disorders, including Parkinson's disease, schizophrenia, bipolar disorder, Huntington's disease, attention deficit hyperactivity disorder (ADHD1), and Tourette's syndrome. Numerous advances have occurred in understanding the general structural, biochemical, and functional properties of dopamine receptors that have led to the development of multiple pharmacologically active compounds that directly target dopamine receptors, such as antiparkinson drugs and antipsychotics. Recent progress in understanding the complex biology of dopamine receptor-related signal transduction mechanisms has revealed that, in addition to their primary action on cAMP-mediated signaling, dopamine receptors can act through diverse signaling mechanisms that involve alternative G protein coupling or through G protein-independent mechanisms via interactions with ion channels or proteins that are characteristically implicated in receptor desensitization, such as β-arrestins. One of the future directions in managing dopamine-related pathologic conditions may involve a transition from the approaches that directly affect receptor function to a precise targeting of postreceptor intracellular signaling modalities either directly or through ligand-biased signaling pharmacology. In this comprehensive review, we discuss dopamine receptor classification, their basic structural and genetic organization, their distribution and functions in the brain and the periphery, and their regulation and signal transduction mechanisms. In addition, we discuss the abnormalities of dopamine receptor expression, function, and signaling that are documented in human disorders and the current pharmacology and emerging trends in the development of novel therapeutic agents that act at dopamine receptors and/or on related signaling events.
- Published
- 2011
49. Un rôle pour la voie de signalisation Akt/GSK3 dans l’action des médicaments psychotropes et les maladies mentales
- Author
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Del’Guidice, Thomas and Beaulieu, Jean-Martin
- Abstract
Les médicaments ciblant la neurotransmission monoaminergique sont utilisés dans le traitement de maladies neuropsychiatriques comme la dépression, les désordres bipolaires et la schizophrénie. La voie de signalisation composée des kinases Akt et glycogen synthase kinase 3(GSK3) semble jouer un rôle important dans la régulation du comportement par les monoamines : dopamine et sérotonine. L’activité de ces kinases est aussi affectée en réponse à plusieurs médicaments psychotropes incluant les antipsychotiques, les antidépresseurs et le lithium. Ce tour d’horizon couvre plusieurs découvertes récentes identifiant les mécanismes par lesquels la dopamine et la sérotonine régulent Akt et GSK3, le rôle de cette voie de signalisation dans l’action de différents médicaments psychotropes et sa possible contribution à la genèse des maladies mentales.
- Published
- 2010
- Full Text
- View/download PDF
50. TreeSNPs: a laboratory information management system (LIMS) dedicated to SNP discovery in trees
- Author
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Clément, Sébastien, Fillon, Joël, Bousquet, Jean, and Beaulieu, Jean
- Abstract
Abstract: TreeSNPs is a laboratory information management system with a user-friendly Web interface for the gathering and display of data generated through medium- to large-scale single nucleotide polymorphism (SNP) identification by resequencing, in the context of whole genome association, outlier detection, quantitative trait locus, and genetic mapping studies. Its multi-gene approach allows the tracking of all the steps from candidate gene classification and prioritization to SNP discovery. The system, source code, and documentation are available for download at http://treesnps-pub.arborea.ulaval.ca:3000/download. An online demo version can also be accessed from the above link.
- Published
- 2010
- Full Text
- View/download PDF
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