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Human immunodeficiency virus (HIV) transmission remains an important health issue, with a high burden that is felt across the world. This work aims to analyze the demographic, clinical, and laboratory characteristics of newly diagnosed patients with HIV in a Department of Dermatology and Venereology. A retrospective observational study was conducted from all health records of newly diagnosed patients with HIV from a Dermatology unit from January 2011 through December 2020. A total of 134 patients with new HIV diagnoses were included in the analysis. Concurrent dermatological or venereal diseases were diagnosed in 91.0% of the patients (n = 122), being the most common conditions syphilis (22.4%, n = 30) and urethritis (14.9%, n = 20). Out of all the patients with diagnoses of concurrent sexually transmitted infection (STI) (41.0%, n = 55), syphilis was reported in 81.8% of the patients (n = 45), gonorrhea in 9.1% (n = 5), and chlamydia in 5.5% (n = 3). We present a large patient database on the clinical conditions associated with newly diagnosed HIV, concluding that infectious diseases were the most common conditions associated with newly diagnosed HIV.

O cancro cutâneo não melanoma é a neoplasia mais prevalente na população caucasiana e a sua incidência está a crescer. Nos últimos anos, um conjunto de estudos sugeriu que a terapêutica anti‐hipertensora poderá aumentar o risco destes tumores, salientando‐se a hidroclorotiazida, pelas suas propriedades fotossensibilizadoras. A crescente evidência disponível levou a Infarmed (Autoridade Nacional do Medicamento e Produtos de Saúde) a realizar um alerta dirigido aos profissionais de saúde para o risco de cancro cutâneo não melanoma com a exposição dos doentes a doses cumulativas deste fármaco. Contudo, os resultados dos estudos têm‐se revelado heterogéneos e, por vezes, contraditórios. A elevada incidência de cancro cutâneo não melanoma e o grande número de indivíduos a cumprir terapêutica crónica com hidroclorotiazida poderão ter importantes repercussões em termos de saúde pública. Neste artigo, os autores propuseram‐se a reunir e analisar a evidência científica disponível, tendo concluído uma possível associação entre a toma de hidroclorotiazida e o risco de cancro cutâneo não melanoma, não esquecendo, no entanto, algumas limitações dos trabalhos existentes na literatura. O reforço de medidas educacionais para a adoção de estratégias preventivas face à exposição solar, a monitorização regular da pele e avaliação individual do benefício da terapêutica com hidroclorotiazida são importantes, em particular na presença de antecedentes pessoais de tumores de pele.

Human monkeypox (MPX) is a zoonotic endemic disease in regions of Africa caused by the monkeypox virus, with a recent outbreak in several non-African countries. We report a case of a 24-year-old male patient with a concurrent diagnosis of MPX and acute HIV infection who presented to our Emergency Care Dermatology Clinic with disseminated papules throughout the trunk, face and genital area. On the perianal area, several grouped umbilicated whitish papules in a kissing lesion configuration could be seen. Laboratory workups were consistent with recent HIV infection, and swab samples from the lesion surfaces were positive for monkeypox virus. We provide novel information on the clinical presentation of MPX, expanding the data pool of the clinical manifestations of which health workers should be aware.