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An 8-yr-old, captive, female golden lion tamarin ( Leontopithecus rosalia) with a 6-yr history of hyperbilirubinemia was examined for inappetence and weight loss. Physical examination and blood pressure monitoring under anesthesia revealed hypothermia and hypotension, and blood work revealed hypoglycemia, markedly elevated liver enzymes, including serum alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase, and confirmed the hyperbilirubinemia. A complete blood count suggested chronic lymphoid leukemia. The animal's condition deteriorated during recovery, and the animal died despite aggressive treatment. Grossly, there was micronodular cirrhosis of the liver, severe icterus, and diffuse osteopenia of all examined bones. Microscopic examination of the liver confirmed the micronodular cirrhosis and bone lesions were compatible with diffuse osteopenia and osteomalacia. This brief communication presents a case of chronic liver disease and lesions indicative of metabolic bone disease, also known as hepatic osteodystrophy. To the authors' knowledge, this is the first documented case of hepatic osteodystrophy in the veterinary literature. [ABSTRACT FROM AUTHOR]

A 24-year-old Thoroughbred mare had a history of weight loss, progressive bilateral hind limb weakness, and ataxia. An infectious neurologic disease was suspected, and the mare was euthanized due to poor prognosis. At necropsy, a yellow firm mass replaced most of the skeletal muscles of the left thigh. Numerous similar nodules were in several other muscles and in multiple organs, including brain and spinal cord. Microscopic examination revealed a leiomyosarcoma with disseminated metastases. Although of rare occurrence, this case is a reminder of noninfectious causes of ataxia in horses. [ABSTRACT FROM AUTHOR]