44 results on '"Chen, Chiung-Tong"'
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2. Targeting the Phosphatidylserine-Immune Checkpoint with a Small-Molecule Maytansinoid Conjugate
3. Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins.
4. Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins
5. Development of Stem-Cell-Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond
6. Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer.
7. Artificial intelligence approach fighting COVID-19 with repurposing drugs
8. Repurposing old drugs as antiviral agents for coronaviruses
9. Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia
10. Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer
11. Linker Optimization and Therapeutic Evaluation of Phosphatidylserine-Targeting Zinc Dipicolylamine-based Drug Conjugates.
12. Discovery of Conformational Control Inhibitors Switching off the Activated c‑KIT and Targeting a Broad Range of Clinically Relevant c‑KIT Mutants.
13. Linker Optimization and Therapeutic Evaluation of Phosphatidylserine-Targeting Zinc Dipicolylamine-based Drug Conjugates
14. Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants
15. CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways
16. An Intestinal “Transformers”-like Nanocarrier System for Enhancing the Oral Bioavailability of Poorly Water-Soluble Drugs
17. PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis
18. Novel Nrf2/AREActivator, trans-Coniferylaldehyde, Induces a HO-1-Mediated Defense Mechanism through a Dual p38α/MAPKAPK-2 and PK-N3 Signaling Pathway.
19. A Novel CXCR4 Antagonist CX549 Induces Neuroprotection in Stroke Brain
20. Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer
21. Correction to "Oral Delivery of Peptide Drugs Using Nanoparticles Self-Assembled by Poly(γ-glutamic acid) and a Chitosan Derivative Functionalized by Trimethylation".
22. Optimizationof Ligand and Lipophilic Efficiency ToIdentify an in Vivo Active Furano-Pyrimidine Aurora Kinase Inhibitor.
23. Discovery of Non-Glycoside Sodium-Dependent Glucose Co-Transporter 2 (SGLT2) Inhibitors by Ligand-Based Virtual Screening.
24. BPR0C305, an orally active microtubule-disrupting anticancer agent
25. Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice
26. Discovery of Potential Neuroprotective Agents against Paclitaxel-Induced Peripheral Neuropathy
27. Correction to “Oral Delivery of Peptide Drugs Using Nanoparticles Self-Assembled by Poly(γ-glutamic acid) and a Chitosan Derivative Functionalized by Trimethylation”
28. Self‐Assembled pH‐Sensitive Nanoparticles: A Platform for Oral Delivery of Protein Drugs
29. Biotransformation of 6-Methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a Novel Antimicrotubule Agent, by Mouse, Rat, Dog, and Human Liver Microsomes
30. Structure-Based Drug Design of a Novel Family of PPARγ Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities
31. Paclitaxel-Loaded Poly(γ-glutamic acid)-poly(lactide) Nanoparticles as a Targeted Drug Delivery System against Cultured HepG2 Cells
32. 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: A Potent, Selective, and Orally Bioavailable Dipeptide-Derived Inhibitor of Dipeptidyl Peptidase IV
33. 2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: A Potent, Selective, and Orally Bioavailable Dipeptide-Derived Inhibitor of Dipeptidyl Peptidase IV
34. Loading of a Novel Angiogenic Agent, Ginsenoside Rg1 in an Acellular Biological Tissue for Tissue Regeneration
35. A Natural Compound (Ginsenoside Re) Isolated from Panax ginseng as a Novel Angiogenic Agent for Tissue Regeneration
36. A Simple Quantitative Method for Evaluation of Angiogenesis Activity
37. Mechanisms of orexin‐induced depolarizations in rat dorsal motor nucleus of vagus neurones in vitro
38. Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1.
39. Discovery of BPR1R024, an Orally Active and Selective CSF1R Inhibitor that Exhibits Antitumor and Immunomodulatory Activity in a Murine Colon Tumor Model
40. BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
41. Discovery of M Protease Inhibitors Encoded by SARS-CoV-2
42. Multifunctional nanoparticles for oral protein drug delivery.
43. 1J373 Is a Promising Agent Against C-KIT driven Acute Myeloid Leukemia
44. 1J373 Is a Promising Agent Against C-KITdriven Acute Myeloid Leukemia
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