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1. Intérêt du dosage de l’antigène galactomannane dans le diagnostic et le suivi de l’histoplasmose disséminée à Histoplasma capsulatum var. duboisii au cours du VIH : enseignement à partir d’un cas clinique.

Author

Therby, A., Polotzanu, O., Khau, D., Monnier, S., Greder Belan, A., and Eloy, O.

Abstract

Résumé: Le diagnostic de l’histoplasmose à Histoplasma capsulatum var. capsulatum repose sur l’examen direct par la mise en évidence de levures capsulées bourgeonnantes à base étroite. L’antigénémie galactomannane est une aide au diagnostic et permet le suivi des patients sous traitement. Le cas d’une patiente séropositive pour le VIH, originaire du Congo Brazzaville, présentant une forme disséminée d’histoplasmose africaine, a permis de mettre en évidence la positivité de l’antigène galactomannane aussi dans cette pathologie due à H. capsulatum var. duboisii. L’antigénémie galactomannane est restée élevée avec une très lente décroissance sous traitement antifongique, parallèlement à la lente régression des lésions cliniques. L’histoplasmose africaine est une maladie rare, de diagnostic difficile, peu décrite chez les sujets immunodéprimés, chez qui les diagnostics différentiels peuvent être nombreux. Cette observation souligne l’intérêt du dosage de l’antigène galactomannane chez les patients ayant séjourné en zone d’endémie. Comme dans le cas d’H. capsulatum var. capsulatum, la positivité de l’antigénémie galactomannane constitue une aide importante au diagnostic et dans le suivi thérapeutique. [Copyright &y& Elsevier]

Published
2014
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2. Sensibilité comparée par CLSI, EUCAST, E-test et ATB® Fungus 2 des souches de Candida sp. isolées au cours d’une enquête épidémiologique sur les candidémies dans des hôpitaux non ...

Author

Rieu, P., Eloy, O., Bertout, S., Mallié, M., Bain, P., and Blanc, V.

Subjects
CANDIDIASIS, PUBLIC health, INFECTIOUS disease transmission, MICROBIOLOGY
Abstract

Copyright of Journal of Medical Mycology / Journal de Mycologie Médicale is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2009
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3. Contribution of the Pittet's index, antigen assay, IgM, and total antibodies in the diagnosis of invasive candidiasis in intensive care unit.

Author

Eloy, O., Marque, S., Mourvilliers, B., Pina, P., Allouch, P.Y., Pangon, B., Bedos, J.P., and Ghnassia, J.C.

Subjects
CANDIDIASIS, INTENSIVE care units, IMMUNOGLOBULINS, MYCOSES
Abstract

Copyright of Journal of Medical Mycology / Journal de Mycologie Médicale is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2006
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4. Pratique de l'antifongigramme dans 62 hôpitaux français.

Author

Blanc, V., Eloy, O., Sanchez, R., and Mallié, M.

Subjects
ANTIFUNGAL agents, DISEASE susceptibility, SURVEYS, MICROBIOLOGY
Abstract

Copyright of Journal of Medical Mycology / Journal de Mycologie Médicale is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2005
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5. Identification et sensibilité aux antifongiques de deux souches de Candida dans 95 hôpitaux français.

Author

Eloy, O., Blanc, V., Mallié, M., Decousser, J.W., Pina, P., and Allouch, P.Y.

Subjects
CANDIDA, VIROLOGY, HOSPITALS, MICROBIOLOGY
Abstract

Copyright of Journal of Medical Mycology / Journal de Mycologie Médicale is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2005
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6. Microsatellite Marker Analysis as a Typing System for Candida glabrata

Author

Foulet, F., Nicolas, N., Eloy, O., Botterel, F., Gantier, J.-C., Costa, J.-M., and Bretagne, S.

Abstract

ABSTRACTCandida glabratais one of the most important causes of nosocomial fungal infection. We investigated, using a multiplex PCR, three polymorphic microsatellite markers, RPM2, MTI, and ERG3, in order to obtain a rapid genotyping method for C. glabrata. One set of primers was designed for each locus, and one primer of each set was dye labeled to read PCR signals using an automatic sequencer. Eight reference strains including other Candidaspecies and 138 independent C. glabrataclinical isolates were tested. The clinical isolates were collected from different anatomical sites of adult patients either hospitalized in different wards of two different hospitals or not hospitalized. Since C. glabratais haploid, one single PCR product for each PCR set was obtained and assigned to an allele. The numbers of different alleles were 5, 7, and 15 for the RPM2, MTI, and ERG3loci, respectively. The number of allelic associations was 21, leading to a discriminatory power of 0.84. The markers were stable after 25 subcultures, and the amplifications were specific for C. glabrata. A factorial correspondence analysis did not indicate any correlation between the 21 multilocus genotypes and the clinical data (source, sex, ward, anatomical sites). Microsatellite marker analysis is a rapid and reliable technique to investigate clinical issues concerning C. glabrata. However, its discriminatory power should be improved by testing other polymorphic microsatellite loci.

Published
2005
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7. Use of Microsatellite Markers and Gene Dosage To Quantify Gene Copy Numbers in Candida albicans

Author

Costa, J.-M., Eloy, O., Botterel, F., Janbon, G., and Bretagne, S.

Abstract

ABSTRACTWith microsatellite marker typing, the number of alleles must be known for calculation of allelic frequencies in the diploid Candida albicansfor a given locus. We describe a gene dosage with a double real-time PCR. Such a dosage should also be useful in exploring the loss of heterozygosity in C. albicans.

Published
2005
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10. Carter leads U.S. delegates at canal ceremony.

Author

Aguilar, Eloy O.

Abstract

Reports that former United States President Jimmy Carter presided over a commemoration of the transfer of the Panama Canal in December 1999, an act he set in motion in 1977.

Published
1999

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