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• To our knowledge, this study is the first study to use serious games to promote psychological resilience in adolescents with T1DM. This study empowers the mental health management of T1DM adolescents with digital technology, providing a digital psychological intervention targeting resilience. • From the findings of this study, serious game-based intervention on promoting resilience is feasible and acceptable in adolescents with T1DM. However, since this is a feasibility study, further scientific inquiry and evidence are necessary before gaming can be recommended broadly as a viable means of facilitating improved health-related outcomes in adolescents with T1DM. • The exploration of this study in digital technology-enabled physical and mental health management for adolescents with T1DM provides a new measure for intelligent and comprehensive management of chronic diseases. The aim of this study is to test the feasibility of a smartphone serious game-based intervention to promote resilience for adolescents with type 1 diabetes mellitus (T1DM). A two-arm feasibility study was employed. Adolescents with T1DM were recruited. Adolescents in intervention group completed the serious game (named " WeCan ") in one month. We evaluated feasibility and acceptability using criteria such as the recruitment response rate, the follow-up response rate, and satisfaction. Sixty-one adolescents with T1DM were included in this study. The study had a recruitment response rate of 62.89% (61/97) and an intervention completion rate of 64.52% (20/31). Eighty-two percent of the adolescents were satisfied with WeCan , which they perceived to have the advantages of being a lively format, attractive, and privacy, easy to operate, and improved attitude towards diabetes. These findings suggest that WeCan demonstrated good feasibility among the target population. However, the efficacy of health-related outcomes needs to be clarified in future studies. [ABSTRACT FROM AUTHOR]

Translocations are a critical tool for reversing biodiversity loss but are often characterized by unreasonably high expectations, leading to many translocation programs being brief and terminated before achieving their full potential. To address these issues, we developed the "Translocation Continuum Framework", an easy‐to‐use tool that clarifies the criteria, strategies, tactics, progress measures, and expected outcomes for five key translocation "phases": Feasibility Studies, Pilot Studies, Primary Trials, Secondary Experiments, and Tertiary Reinforcements. By accounting for uncertainty, the Framework aims to empower practitioners to design translocation programs that suit their context. We also discuss the limitations of "success" and "failure" labels in translocations, and the importance of parsimonious decision making to maximize learning with the least amount of loss. Only by managing expectations of the likelihood of establishment, growth, and regulation throughout a program's lifetime can we galvanize trust and investment in translocations so they can contribute meaningfully to long‐term restoration. [ABSTRACT FROM AUTHOR]

Thermogravimetry (TG) is used to measure the change of sample mass versus temperature or time under a program controlling temperature. It is a common thermal analysis tool with a precise built-in balance, and accurate data can be obtained through a small amount of sample at the level of milligrams. The feasibility of the TG method for determining maximum water content (MWC) measurement of waterlogged archaeological wood was studied. Simulated waterlogged wood and waterlogged archaeological wood were used to determine the test condition for the TG method. MWC data obtained through the oven-dry and TG methods with different mass gradients from 0–10 mg to >50 mg were analyzed statistically. Deviation, error bar, and coefficient of variation were evaluated. According to the results, when sample mass is no less than 30 mg, and holding time at 105°C is no less than 40 min, data deviation between these two methods is less than 5%. Effect of sampling depth and presence of inorganic deposits were also investigated. Specimens were taken from an archaeological wood with a sampling depth from 2 to 6 mm, then MWC was measured through the TG method. The results indicate MWC of the samples taken from a depth of 2–4 mm is higher than that taken from a depth of 0–2 mm and is lower than that taken from a depth of 4–6 mm, which is related to inorganic deposits. The presence of deposits was verified through SEM-EDX. MWC of three archaeological wood samples from China and five archaeological wood samples from Italy were measured to verify the effectiveness of the TG method when wood species and degradation degree are different. [ABSTRACT FROM AUTHOR]

Purpose: To assess the feasibility of implementing Listening Visits (LV) in an Italian neonatal intensive care unit (NICU). Study Design and Methods: This feasibility implementation of LV included empathic listening and problem-solving sessions provided by a psychologist to 26 parents of hospitalized preterm newborns. Using the RE-AIM implementation framework, three facets of feasibility were assessed: reach , adoption , and implementation. Results: It is feasible to integrate LV into the NICU: 76% of families were willing to try LV (reach). Listening Visits recipients reported high satisfaction. Twelve of the 16 families (75%) received six or more LV sessions (adoption), with mothers attending more sessions. Implementation fidelity , defined here as the percentage of LV recipients that received at least four sessions, was 94% among mothers and 30% among fathers. Clinical Implications: The LV intervention for parental support during the NICU stay is feasible and deemed helpful by parents. Parents were motivated to participate even though their levels of depression, stress, and anxiety were not high. In addition to the use of standardized screening questionnaires, parental requests and clinical team indications should be included in the decision-making for the provision of parental support services. Listening Visits are among a variety of interventions specifically aimed at supporting depressed mothers of hospitalized newborns. In this study, feasibility of implementation of Listening Visits for parents of babies hospitalized in a neonatal intensive care unit in Pisa, Italy included empathic listening and problem-solving sessions provided by a psychologist. Participation by parents was high and they were appreciative of the interactions. Feasibilty of the Listening Visists intervention was established in this clincal setting. [ABSTRACT FROM AUTHOR]

The fraction of materials that does not reach the target product in discrete manufacturing is very significant. Directing secondary material streams towards other manufacturing processes, possibly after intermediate pre-processing, offers opportunities for more energy and resource efficient recycling routes. This paper contributes to the exploration of such symbiotic recycling strategies by identifying relevant process mechanisms and by systematically scanning the manufacturing domain for relevant process combinations. Emerging and proven symbiotic combinations within the discrete manufacturing domain are reviewed, with proper attention for the quantification of the thus avoided environmental impact. A series of representative case studies illustrates the feasibility of applying industrial symbiosis principles in a discrete manufacturing context, with uniform data sheets providing detailed information on relevant research achievements. [ABSTRACT FROM AUTHOR]

Purpose: Neurotoxicity concerns have been raised over general anesthesia and sedation medication use in children. Such concerns are largely based on animal studies, historical anesthetic agents, and assessment tools, thus warranting further investigations. Blood biomarkers in detecting neuronal inflammation and apoptosis are novel methods for detecting neuronal damage. Therefore, the aim of this feasibility study was to assess the usefulness of the levels of four plasma biomarkers in dental general anesthesia (DGA) as surrogate markers of neurotoxicity in children. The secondary aim was to compare changes in motor manipulative skills pre- and post-anesthetic exposure. Methods: This single-center prospective observational study included 22 healthy children aged between 3 and 6 years old who underwent DGA. Subclinical neurotoxicity was measured with a panel of four plasma biomarkers: Caspase-3, neuron-specific enolase (NSE), neurofilament light chain, and S100B at three time points (1; at start, 2; end and 3; on recovery from DGA). The Skillings–Mack test was used to identify the difference in the biomarker levels at three time points. Motor manipulative score assessment, prior and two weeks after DGA was also performed. Results: A total of 22 study participants (mean age = 5 ± 1 years) were included with a median DGA duration of 106 ± 28 min. A reduction in Caspase-3 levels was recorded, with pairwise comparison over three time points, reporting a statistical significance between time point 2 vs. 1 and time point 3 vs. 1. Although fluctuations in NSE levels were recorded, no significant changes were found following pairwise comparison analysis. Among other biomarkers, no significant changes over the three periods were recorded. Furthermore, no significant changes in manipulative motor scores were reported. Conclusion: Caspase-3 reduced significantly in the short time frames during day-care DGA; this might be due to the relatively short anesthesia duration associated with dental treatment as compared with more extensive medical-related treatments. Therefore, further studies on Caspase-3 as a potential biomarker in pediatric DGA neurotoxicity are required to further ascertain results of this study. [ABSTRACT FROM AUTHOR]

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For successful nasal reconstruction using a forehead flap, three-dimensional (3D) nasal defects need to be translated into a two-dimensional (2D) forehead surface. For this study, a patient-specific 3D-printed forehead flap guide that could precisely translate a virtually simulated nasal shape into a 2D flap template was developed. The study aimed to evaluate the feasibility and efficacy of a 3D-printed forehead flap guide for nasal reconstructions. The 3D nasal surface was scanned using a 3D camera, and a 'digital clay' process was performed to correct the nasal deformity. The 3D morphology was flattened into a 2D forehead flap guide. The guide was 3D-printed and used for the forehead flap design. Photographic records were used to conduct anthropometric and aesthetic evaluations. Between October 2016 and August 2020, forehead flaps were performed using the forehead flap guide (guide group) and traditional templating method (control group) in 16 and 15 patients, respectively. The alar shape was more symmetric in the guide group than in the control group, with smaller right-to-left differences in alar width (p = 0.01) and height (p = 0.05). Regarding aesthetic evaluations, nose contour (p = 0.02) and nasal symmetry (p = 0.033) were better in the guide group than in the control group. The mean operative time was significantly shorter (91.9 ± 10.7 min) in the guide group than in the control group (116.4 ± 13.6 min) (p = 0.001). Our findings suggest that a 3D-printed forehead flap surgical guide can be effectively used in nasal reconstruction to reduce operative time and improve aesthetic outcomes. [ABSTRACT FROM AUTHOR]

Chile is a country that has had large renewable energy resources in recent years, and it has demonstrated a commitment to the use of clean energy. However, most solar energy projects are located in northern Chile, neglecting other areas, such as the southern part of the country, where the photovoltaic energy industry has the potential to thrive. This is the case in the Araucanía region, particularly in Temuco, which has diverse agricultural activity. However, being a remote area without access to the electrical grid, it relies on generation sources like oil. This article, a research product, aims to demonstrate the functionality that can be added to agricultural land by combining it with solar parks. To achieve this, an agrovoltaic system was estimated for a plot of land in the agricultural zone of Temuco. This system will serve as a sample of the integration between photovoltaic infrastructure and the agricultural industry for those interested in installing it. [ABSTRACT FROM AUTHOR]

Background: Boxing training has become a popular form of exercise for people with Parkinson disease (PD). There is a dearth of high‐quality feasibility, safety, and efficacy data on boxing training for PD. Feasibility of Instituting Graduated High‐intensity Training (FIGHT‐PD) aimed to examine these features in a periodized boxing training program featuring high‐intensity physical and cognitive demands. Objective: To conduct a feasibility study, aiming to address deficiencies in the current knowledge base and to provide data for future studies. Design: Single‐arm, open‐label feasibility. Setting: University department and medical research institute. Participants: Ten people with early stage PD without contraindications to intense exercise, identified from a database of participants interested in boxing training. Interventions: A 15‐week exercise program with three 1‐hour sessions per week, with each session including warmup and then rounds of noncontact boxing using a training device. Three distinct blocks of 5 weeks including active rest.Boxers Development: focus on training techniqueBoxers Cardio: increasing intensity, including high‐intensity interval trainingBoxers Brain: focus on cognitively challenging dual task training Main Outcome Measures: Process, resource, and management measures including recruitment and retention rates, timelines and costs, and compliance with prescribed exercise targets. Clinical outcomes were safety (adverse events), training intensity (using heart rate and perceived exertion monitoring), tolerability (pain, fatigue, and sleep scores), and pre‐ and postprogram Unified Parkinson Disease Rating Scale (UPDRS‐III). Results: Among 10 participants from a pool of 82 (recruitment rate = 12%), there were no withdrawals; 348/360 workouts were completed (adherence = 97.7%); 4/348 (1.1%) workouts were missed due to minor injury. Nine of 10 participants showed improvement in UPDRS motor score. Conclusions: FIGHT‐PD provides a depth of feasibility and safety data, methodological detail, and preliminary results that is not described elsewhere and could provide a useful basis for future studies of boxing training for PD. [ABSTRACT FROM AUTHOR]

A comprehensive study on the feasibility of Lithium (Li)-ion battery technology for Light Weight Torpedoes (LWT) and Heavy Weight Torpedoes (HWT) applications are reported in this article. The global scenario of Li-ion battery technology for torpedo applications and current Indigenous Li-ion battery developments in India are studied. Configuration study of Li-ion battery for LWT and HWT with commercial cells was carried out and it is found feasible to partially meet the required power for LWT and HWT applications. A comparison of the cost per cycle of Li-ion battery versus AgO-Zn battery indicates that Li-ion batteries work out to be cheaper beyond 100 cycles of use and by an order of magnitude cheaper on average. The detailed survey on Indigenous developments reveals that cell-level development is predominant in public sector agencies, whereas the private sector is mostly focussed on the assembly of imported cells and BMS. [ABSTRACT FROM AUTHOR]

BACKGROUND: Our aim was to assess the feasibility of repeat transcatheter aortic valve (TAV) replacement for degenerated Sapien3 (S3) prostheses by simulating subsequent implantation of S3 or Evolut, using in vivo computed tomography--based sizing and the impact on coronary and patient-prosthesis mismatch risks. METHODS: Computed tomography scans from 356 patients with prior S3 TAV replacement implantation were analyzed. The in vivo sizing for second TAV based on averaged area of 3 levels of outflow, mid (narrowest) and inflow, was compared with in vitro recommendations, that is, same size as index S3 for second S3 and 1 size larger for Evolut. Risks of coronary obstruction and patient-prosthesis mismatch were determined by valve-to-aorta distance and estimated effective orifice area, respectively. RESULTS: Overall, the majority of patients (n=328; 92.1%) had underexpanded index S3 with an expansion area of 94% (91%-97%), leading to significant differences in size selection of the second TAV between in vivo and in vitro sizing strategies. Expansion area <89% served as a threshold, resulting in 1 size smaller than the in vitro recommendations were selected in 45 patients (13%) for S3-in-S3 and 13 (4%) for Evolut-in-S3, while the remaining patients followed in vitro recommendations (P<0.01, in vivo versus in vitro sizing). Overall, 57% of total patients for S3-in-S3 simulation and 60% for Evolut-in-S3 were considered low risk for coronary complications. Deep index S3 implantation (odds ratio, 0.76 [interquartile range, 0.67-0.87]; P<0.001) and selecting Evolut as the second TAV (11% risk reduction in intermediate- or high-risk patients) reduced coronary risk. Estimated moderate or severe patient-prosthesis mismatch risk was 21% for S3-in-S3 and 1% for Evolut-in-S3, assuming optimal expansion of the second TAV. CONCLUSIONS: Redo-TAV replacement with S3-in-S3 and Evolut-in-S3 could be feasible with low risk to coronaries in ≈60% of patients, while the remaining 40% will be at intermediate or high risk. The feasibility of redo-TAV replacement is influenced by sizing strategy, type of second TAV, native annular anatomy, and implant depth. [ABSTRACT FROM AUTHOR]

Key summary points: Aim: The aim of the work is to characterize the study population in whom reactive balance training on a perturbation treadmill was feasible. Findings: More than half of the participants had some cognitive impairment with < 24 pts. (median MoCA 21 pts.), 35% were prefrail and 61% were frail. The drop-out rate was initially 31% and was reduced to 12% after adding a short pre-test on the treadmill. Message: Reactive balance training on a perturbation treadmill is feasible for prefrail and frail geriatric patients. Purpose: Prefrail and frail geriatric patients are at high risk of falling. Perturbation-based balance training on a treadmill appears to be highly effective, but there are no studies in prefrail and frail geriatric hospital patients. The aim of the work is to characterize the study population in whom reactive balance training on a perturbation treadmill was feasible. Methods: The study is recruiting patients with at least one fall event in the past year (age ≥ 70). The patients complete a minimum of 60-min treadmill training with/without perturbations on at least 4 occasions. Results: Until now, 80 patients (mean age 80 ± 5) took part in the study. More than half of the participants had some cognitive impairment with < 24 pts. (median MoCA 21 pts.), 35% were prefrail and 61% were frail. The drop-out rate was initially 31% and was reduced to 12% after adding a short pre-test on the treadmill. Conclusion: Reactive balance training on a perturbation treadmill is feasible for prefrail and frail geriatric patients. Its effectiveness in fall prevention in this population needs to be proven. Trial registration: German Clinical trial register (DRKS-ID: DRKS00024637 on 24.02.2021). [ABSTRACT FROM AUTHOR]

BACKGROUND: Adrenal venous sampling is recommended for the identification of unilateral surgically curable primary aldosteronism but is often clinically useless, owing to failed bilateral adrenal vein cannulation. OBJECTIVES: To investigate if only unilaterally selective adrenal vein sampling studies can allow the identification of the responsible adrenal. METHODS: Among 1625 patients consecutively submitted to adrenal vein sampling in tertiary referral centers, we selected those with selective adrenal vein sampling results in at least one side; we used surgically cured unilateral primary aldosteronism as gold reference. The accuracy of different values of the relative aldosterone secretion index (RASI), which estimates the amount of aldosterone produced in each adrenal gland corrected for catheterization selectivity, was examined. RESULTS: We found prominent differences in RASI values distribution between patients with and without unilateral primary aldosteronism. The diagnostic accuracy of RASI values estimated by the area under receiver operating characteristic curves was 0.714 and 0.855, respectively, in the responsible and the contralateral side; RASI values >2.55 and ≤0.96 on the former and the latter side furnished the highest accuracy for detection of surgically cured unilateral primary aldosteronism. Moreover, in the patients without unilateral primary aldosteronism, only 20% and 16% had RASI values ≤0.96 and >2.55. CONCLUSIONS: With the strength of a large real-life data set and use of the gold reference entailing an unambiguous diagnosis of unilateral primary aldosteronism, these results indicate the feasibility of identifying unilateral primary aldosteronism using unilaterally selective adrenal vein sampling results. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT01234220. [ABSTRACT FROM AUTHOR]

As the closing article of the Special Issue of TRR, 'Vulnerabilities and Viabilities in Tourism Studies', the paper takes each one of the articles in the issue as reference and looks in them at concurrences and diffractions concerning claims of vulnerability and viability proposals for the field of tourism studies. The paper problematizes current practices of tourism research, and focuses on the vulnerability of tourism scholarship; postdiciplinarity in tourism studies; onto-ethico-epistemological enrichments for the field and futuring as worldmaking in the search of new viabilities. As a result, the meaning and placement of the field's vulnerability is overturned and new viabilities for a 'more-than-tourism' field of tourism studies are proposed. [ABSTRACT FROM AUTHOR]

The purpose of this ambispective study was to investigate whether deep learning-based automatic segmentation and landmark detection, the SkullEngine, could be used for orthognathic surgical planning. Sixty-one sets of cone beam computed tomography (CBCT) images were automatically inferred for midface, mandible, upper and lower teeth, and 68 landmarks. The experimental group included automatic segmentation and landmarks, while the control group included manual ones that were previously used to plan orthognathic surgery. The qualitative analysis of segmentation showed that all of the automatic results could be used for computer-aided surgical simulation. Among these, 98.4% of midface, 70.5% of mandible, 98.4% of upper teeth, and 93.4% of lower teeth could be directly used without manual revision. The Dice similarity coefficient was 96% and the average symmetric surface distance was 0.1 mm for all four structures. With SkullEngine, it took 4 minutes to complete the automatic segmentation and an additional 10 minutes for a manual touchup. The results also showed the overall mean difference between the two groups was 2.3 mm for the midface and 2.4 mm for the mandible. In summary, the authors believe that automatic segmentation using SkullEngine is ready for daily practice. However, the accuracy of automatic landmark digitization needs to be improved. [ABSTRACT FROM AUTHOR]

Recently, a specific interest is being taken in the development of mobile application (app) via Model-Based User Interface Development (MBUID) approach. MBUID allows the generation of mobile apps in the target platform(s) from conceptual models. As such it simplified the development process of mobile app. However, the interest is only focused on the functional aspects of the mobile app while neglecting the non-functional aspects, such as usability. The latter is largely considered as the main factor leading to the success or failure of any software system. This paper aims at addressing non-functional aspects of mobile apps generated using MBUID approach. As such, we propose a usability-driven approach for the development of mobile apps. The main stages of the proposed approach are defined in a generic way so that they can be integrated with any MBUID method. A case study is presented, in the paper, with the aim of illustrating the feasibility of this approach. [ABSTRACT FROM AUTHOR]

Unmanned Aerial Vehicles (UAVs) or drones introduced for military applications are gaining popularity in several other fields as well such as security and surveillance, due to their ability to perform repetitive and tedious tasks in hazardous environments. Their increased demand created the requirement for enabling the UAVs to traverse independently through the Three Dimensional (3D) flight environment consisting of various obstacles which have been efficiently addressed by metaheuristics in past literature. However, not a single optimization algorithms can solve all kind of optimization problem effectively. Therefore, there is dire need to integrate metaheuristic for general acceptability. To address this issue, in this paper, a novel reinforcement learning controlled Grey Wolf Optimisation-Archimedes Optimisation Algorithm (QGA) has been exhaustively introduced and exhaustively validated firstly on 22 benchmark functions and then, utilized to obtain the optimum flyable path without collision for UAVs in three dimensional environment. The performance of the developed QGA has been compared against the various metaheuristics. The simulation experimental results reveal that the QGA algorithm acquire a feasible and effective flyable path more efficiently in complicated environment. [ABSTRACT FROM AUTHOR]

It's a big challenge for businesses to increase security in the age of digital technologies, especially for online shops. In online shopping, hackers can penetrate networks and steal private information about customers. Biometrics are still not being used by online retailers in Indonesia as a form of payment security. In this essay, we'll talk about how biometrics might increase online transaction security and effectiveness. [ABSTRACT FROM AUTHOR]

To investigate the anatomical feasibility of the infraspinatus branch of the suprascapular nerve (IB-SSN) reconstruction by lower subscapular nerve (LSN) transfer. The morphological study was performed on 18 adult human cadavers. The length of the distal stump of the IB-SSN, the length of the LSN available for reconstruction and diameter of both stumps were measured. The feasibility study of the LSN to IB-SSN transfer was performed. The mean length of the IB-SSN to the end of its first branch was 40.9 mm (±4.6). Its mean diameter was 2.3 mm (±0.3). The mean length of the LSN stump, which was mobilized from its original course and transferred to reach the distal stump of the IB-SSN was 66.5 mm (±11.8). Its mean diameter was 2.1 mm (±0.3). The mean ratio between LSN and IB-SSN diameters was 0.9 (±0.1). The nerve transfer was feasible in 17 out of 18 cases (94.4%). This study demonstrates that direct LSN to IB-SSN transfer is anatomically feasible in most cases in the adult population. It may be used in cases of complex scapular fractures resulting in severe suprascapular nerve injury. [ABSTRACT FROM AUTHOR]

This study investigated the feasibility of adopting an automatic scoring system (ASS) in a domestic English-speaking education context. Scope, test items, assessment criteria, scoring methods, and reporting strategies of six overseas English-speaking tests utilizing ASSs were examined. Moreover, a comparative analysis was conducted to identify disparities between ASS-based and non-ASS-based speaking tests. Findings were: 1) some ASS-based tests utilized ASS technology throughout the assessment, while others adopted a hybrid scoring system involving human raters; 2) compared to non-ASS-based tests, ASS-based tests used more test items targeting low-level skills such as sound and forms but fewer test items targeting conversation and discourse level skills; 3) pronunciation, fluency, and vocabulary were widely employed as evaluation criteria with sparse use of organization, content, and task completion in most ASS-based tests; 4) differences were minimal in assessment criteria application and score calculation between ASS-based and non-ASS-based tests; and 5) some ASS-based tests provided criteria-specific results and feedback with total scores and proficiency levels. [ABSTRACT FROM AUTHOR]

The formalism of Simple Temporal Networks (STNs) provides methods for evaluating the feasibility of temporal plans. The basic formalism deals with the consistency of quantitative temporal requirements on scheduled events. This implicitly assumes a single agent has full control over the timing of events. The extension of Simple Temporal Networks with Uncertainty (STNU) introduces uncertainty into the timing of some events. Two main approaches to the feasibility of STNUs involve (1) where a single schedule works irrespective of the duration outcomes, called Strong Controllability, and (2) whether a strategy exists to schedule future events based on the outcomes of past events, called Dynamic Controllability. Case (1) essentially assumes the timing of uncertain events cannot be observed by the agent while case (2) assumes full observability. The formalism of Partially Observable Simple Temporal Networks with Uncertainty (POSTNU) provides an intermediate stance between these two extremes, where a known subset of the uncertain events can be observed when they occur. A sound and complete polynomial algorithm to determining the Dynamic Controllability of POSTNUs has not previously been known; we present one in this paper. This answers an open problem that has been posed in the literature. The approach we take factors the problem into Strong Controllability micro-problems in an overall Dynamic Controllability macro-problem framework. It generalizes the notion of labeled distance graph from STNUs. The generalized labels are expressed as max/min expressions involving the observables. The paper introduces sound generalized reduction rules that act on the generalized labels. These incorporate tightenings based on observability that preserve dynamic viable strategies. It is shown that if the generalized reduction rules reach quiescence without exposing an inconsistency, then the POSTNU is Dynamically Controllable (DC). The paper also presents algorithms that apply the reduction rules in an organized way and reach quiescence in a polynomial number of steps if the POSTNU is Dynamically Controllable. Remarkably, the generalized perspective leads to a simpler and more uniform framework that applies also to the STNU special case. It helps illuminate the previous methods inasmuch as the max/min label representation is more semantically clear than the ad-hoc upper/lower case labels previously used. [ABSTRACT FROM AUTHOR]

Copyright of Inonu University Journal of the Faculty of Education (INUJFE) is the property of Inonu University Journal of the Faculty of Education and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

• Virtual reality simulation could close a gap in cultural competence education. • The content of a new virtual simulation was designed based on theoretical models. • The immersive virtual simulation had high levels of usability and satisfaction. Educational approaches proven to produce cultural competence among nurses, consistently and cost-effectively, are not yet widely available. This study describes the development and feasibility of an immersive virtual reality simulation to improve cross-cultural communication skills. We used a multi-methods approach, recruiting 15 nursing students from a nursing college in South Korea to assess the simulation's feasibility according to sense of presence, usability, simulation design, task difficulty, and satisfaction. This theory-based immersive virtual reality simulation was developed through content and face validity testing by expert panels. We identified high levels of usability, simulation design, and satisfaction, a low level of task difficulty, and a good level of sense of presence. Participants were satisfied with the simulation "feeling real and immersive," "improved cultural competence," "useful for repetitive learning," "appropriate difficulty for learning," and "easy to control." Reports of "insufficient prior information," "insufficient cognitive fidelity," "limited to dialogue selection," and "discomfort for wearers of glasses" indicate needed improvements. Virtual reality simulation could contribute to filling a critical gap in cultural competence in nursing education. [ABSTRACT FROM AUTHOR]

Surgical staging in endometrial cancer includes a systematic lymphadenectomy with significant morbidity, although its therapeutic role is unclear. Sentinel lymph node (SLN) study is a less morbid alternative to identify nodes most likely to be metastatic, permitting selective removal and thus reducing morbidity without compromising oncological safety. This study was done using blue dye single labelling to study the feasibility and utility in identifying SLN in early disease. Twenty-two patients of early-stage low-risk disease during surgical staging underwent cervical injection of methylene blue, SLN mapping, and sampling as per the standard algorithm, followed by a systematic lymphadenectomy in all cases. SLN were submitted separately for ultrastaging (US). Twenty patients underwent the procedure, and SLN could be identified in 18 patients with an overall mapping rate of 90% with a bilateral mapping rate of 70%, and a negative mapping rate of 10%. 57 SLN were identified along with two suspicious non-sentinel nodes and 11 were metastatic on US with a sensitivity of 66.7% and NPV of 87.5%. All patients with metastatic nodes, however, could be identified by applying the standard SLN algorithm for sampling. SLN mapping algorithm with blue dye single labelling in early endometrial cancer, by identifying LN most likely to be metastatic enabling their selective removal may help avoid routine lymphadenectomies without compromising oncological safety. The procedure is simple and can be practiced at all centres and can also aid pathologists by pinpointing the likely metastatic nodes after a selective or complete lymphadenectomy. [ABSTRACT FROM AUTHOR]

Purpose: Mobile health technology and integration of patient-reported outcome measures into clinical interventions have the potential to transform patient care. Though patient-reported outcome measure management has been shown to improve outcomes in ambulatory care settings, few studies have examined remote patient-reported outcome measure assessment after major cancer surgery. Materials and Methods: A multiphased feasibility and usability study was designed. A mobile app-based postoperative symptom intervention tool was developed and evaluated by a focus group of bladder cancer patients and caregivers. Patients were prospectively accrued prior to cystectomy and asked to complete the daily mobile postoperative symptom intervention tool and wear biometric monitoring devices for 30 days post discharge. Retention, postoperative symptom intervention tool completion, and usability were assessed. Exploratory analysis of daily symptoms and patient-generated health information correlated signals with postsurgical complications and hospital readmission. Results: Fifteen patients with a median age of 72 years completed 78% of daily surveys over the 30-day recovery period. Average time to complete the postoperative symptom intervention tool was 152 seconds. All patients agreed that the daily survey was easy to use, and most reported it would be a better way to communicate with the care team about symptoms than calling the clinic. Frequency and severity of patient-reported symptoms appeared to cluster prior to or at the time of complication or unplanned health care encounters on visual-analogue mapping. Conclusions: Using smartphone and wearable technology to capture patient-reported symptoms and biometric data is feasible and rated as highly usable by bladder cancer patients after cystectomy. Symptom scores may signal developing complications and help clinicians identify postsurgical patients who may benefit from intervention. [ABSTRACT FROM AUTHOR]

Copyright of Pregled is the property of University of Sarajevo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Brasileira de Medicina do Esporte is the property of Redprint Editora Ltda. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose To assess the magnitude of differences between attenuation values of the true non-contrast image (TNC) and virtual non-contrast image (VNC) derived from twin-beam dual-energy CT (tbDECT) and dual-source DECT (dsDECT). Materials and Methods This retrospective study included 62 patients who underwent liver dynamic DECT with tbDECT (n = 32) or dsDECT (n = 30). Arterial VNC (AVNC), portal VNC (PVNC), and delayed VNC (DVNC) were reconstructed using multiphasic DECT. Attenuation values of multiple intra-abdominal organs (n = 11) on TNCs were subsequently compared to those on multiphasic VNCs. Further, we investigated the percentage of cases with an absolute difference between TNC and VNC of ≤ 10 Hounsfield units (HU). Results For the mean attenuation values of TNC and VNC, 33 items for each DECT were compared according to the multiphasic VNCs and organs. More than half of the comparison items for each DECT showed significant differences (tbDECT 17/33; dsDECT 19/33; Bonferroni correction p < 0.0167). The percentage of cases with an absolute difference ≤ 10 HU was 56.7%, 69.2%, and 78.6% in AVNC, PVNC, and DVNC in tbDECT, respectively, and 70.5%, 78%, and 78% in dsDECT, respectively. Conclusion VNCs derived from the two DECTs were insufficient to replace TNCs because of the considerable difference in attenuation values. [ABSTRACT FROM AUTHOR]

Copyright of Magis: Revista Internacional de Investigación en Educación is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Movement screening to identify abnormal movement patterns can inform development of effective interventions. The primary objective of this study was to evaluate the feasibility of using a movement screening tool in combination with a tailored movement control retraining programme in young soccer and rugby football players. A secondary objective was to investigate changes in movement control patterns post-intervention, to provide proof of concept (PoC) for movement retraining. 52 male amateur players, including 34 soccer players (mean age 15 ± 2 years) and 18 rugby players (mean age 15 ± 1 years) participated. They were screened for movement control ability using a shortened version of the Hip and Lower Limb Movement Screening (Short-HLLMS) and completed an eight-week movement control retraining programme. Evaluation of feasibility included consent from players invited, adherence, attendance at the exercise sessions, drop-out and adverse events. Short-HLLMS total score and The Copenhagen Hip and Groin Outcome Score (HAGOS) were analysed to provide PoC for retraining movement control. feasibility outcomes were favourable. Significant statistical changes occurred post-intervention in the Short-HLLMS total score (paired-samples t -test) and in three HAGOS subscales (symptoms, physical function in daily living and in sport and recreation) (Wilcoxon-Signed Rank Test) in both groups. Feasibility of using the Short-HLLMS in combination with a movement control retraining programme in soccer and rugby players was promising. The data provided PoC for the potential application of a shortened version of the HLLMS to evaluate changes in movement control and to inform targeted motor control programmes. [ABSTRACT FROM AUTHOR]

Assessment of tumor response in rectal cancer after neoadjuvant treatment by MRI (Tumour Regression Grade, TRG 1–5) is well standardized. The overall timing and method of defining complete response (cCR) remain controversial. The aim of this work was to evaluate the feasibility of a defined Response Surveillance Program (RSP) to increase organ preservation for locally advanced rectal cancer after neoadjuvant treatment. A standardized program of clinical (CR), radiological (RR) and metabolic (MR) assessment of tumor response is defined over a 6 month period from completion of NACRT with formal assessment performed every 2 months (M). Patients with TRG1-3 at M2 and TRG1-2 at M4 continue in the program up to M6 assessment. Patients managed with this protocol from 2016 to 2020 were analyzed. The primary endpoint was rectal preservation rate. Secondary endpoints included disease-free survival and overall survival at 3 years. 314 potentially suitable patients were enrolled in the RSP and 50 patients completed the six month program and were successfully enrolled into watch and wait. Fourteen (28%) were T2 tumor stage, 27 (54%) T3 and nine (18%) were T4. During watch and wait, patients with locoregional recurrence (n = 11) were treated with local excision (n = 3), endocavitary radiotherapy (n = 1), TME (n = 5) and APR (n = 2). With a median follow-up of 32 months, the rectal preservation rate was 88%, with a 3-year disease-free survival of 67% and an overall survival of 98%. This study validates the feasibility of the practical implementation of a Response Surveillance Program to increase organ preservation rates without compromising oncological outcomes in rectal cancer. [ABSTRACT FROM AUTHOR]

This study aimed to evaluate the feasibility and acceptability of a nurse-led eHealth transition care program for adolescents with spina bifida. This study used a single-arm, pretest-posttest intervention study. Adolescents with spina bifida, aged 12–15 years, and their parents participated in the program. A 6-week program was delivered through an online platform in real-time by nurses. We evaluated feasibility and acceptability using criteria such as the completion rate, program satisfaction, changes in transition readiness, social support, career preparation behavior, sexual knowledge, and sexual worries at three time points from July to September 2021. Thirteen adolescents completed all sessions and surveys (13/14, 92.9%). All adolescents expressed high satisfaction with both the content and delivery methods of the program. Significant benefits in transition readiness, career preparation behavior, and sexual knowledge were identified over the study period. However, the evaluation of social support and sexual worries did not demonstrate any significant improvements. Additionally, through family counseling, adolescents benefited from experiences such as reflecting on their current transition readiness, setting and achieving individualized goals and plans using a self-checklist with their parents and nursing professionals. This nurse-led eHealth intervention was feasible and acceptable for adolescents with spina bifida. Furthermore, our results highlight the practicability and the potential for strategic dissemination of using this eHealth program in transitional care during the COVID-19 pandemic. The eHealth transition care program contributes to broadening existing nursing interventions not only in medical areas but also in daily life areas. • Spina bifida transition programs should be tailored to developmental stage and need. • These transition programs benefit health self-management and future preparation. • Adolescents are motivated when they are taught importance of transition. • An individualized approach involving parents can facilitate transition readiness. • Nurse-led eHealth interventions are feasible and acceptable during COVID-19. [ABSTRACT FROM AUTHOR]

This study presents a computer platform for online access named SADEMON. The computational model consists of implementing the SAPEVO-M method, enabling the integration of multiple decision-makers in a decision-making analysis process through ordinal inputs. The tool was developed in Python, providing a user-friendly interface for interaction. As a demonstration of the implementation of the computational model, the research present a case study for the feasibility of installing a new branch of a supermarket chain, from the moment given the problem, it consists of multiple stakeholders and different evaluation criteria. At the end of the application, the main points of the proposed model and proposal for future research are presented. [ABSTRACT FROM AUTHOR]

Using wave energy to supply the electrical demand of the coastal population is an exciting idea. In recent years, many wave energy converters (WEC) have been invented, researched, and used in different parts of the world. These WECs can be used alone or in a hybrid system with other renewable resources. Also, they can be used stand-alone or grid-connected to generate electricity. Iran has access to the sea from the north and south. Using wave energy to provide power can be a good solution for energy production. This study investigates the application of a point absorber WEC named CETO to supply electricity for a 300 population on the Coasts of the Caspian Sea, Persian Gulf, and Oman sea. Waves scatter diagram for three locations calculated based on the data collected by the Iranian National Center of Ocean Data. According to these diagrams, the average wave height and period on the Konarak coast in the Oman Sea were 69 cm and 5.4 s, respectively, and Konarak had the best wave condition between the desired location in terms of wave energy potential. Also, the Cost of Energy (COE) and Net Present Cost (NPC) for three areas calculated, and the lowest amount of COE and NPC occurred in Konarak. The COE range at Konarak was between 0.523 and 0.991 $/kWh for different WEC numbers. The best performance in terms of power generation and emissions reduction also occurred in Konarak; and the output power of each CETO unit was 23.01 kW, and emissions and related penalties reduced by about 24 %. Also, the effect of load change and grid extension cost on financial results sensitively analyzed, and the results presented. The obtained financial results compared with the results of some similar WECs and it was found that the obtained results differed very little from the results of other research, and were within their range. • Waves scatter diagram calculated for three coastal locations according to Iranian National Institute for Oceanography data. • CETO wave energy converter output power is calculated in three coastal cities; Kiashahr, Asaluyeh, and Konarak. • Economic parameters such as Cost of Energy, Net Present Cost, and initial capital were calculated, and compared. • The amount of power purchased, and sold to the grid in all three areas were calculated, and compared. • Environmental effects, and amount of emissions reduction, and environmental penalties in case of using CETO were presented. [ABSTRACT FROM AUTHOR]

Copyright of Arquivos de Neuro-Psiquiatria is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Social Affairs is the property of Journal of Social Affairs and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Digital dental articulation for three-piece maxillary orthognathic surgery is challenging. The purpose of this proof-of-concept study was to evaluate the clinical feasibility of a newly developed mathematical algorithm to digitally establish the final occlusion for three-piece maxillary surgery. Five patients with jaw deformities who had undergone a three-piece double-jaw surgery that was planned virtually were randomly selected for this study. The final occlusion had been hand-articulated using stone casts, scanned into the computer and used in the surgery. These hand-articulated occlusions served as the control group. To form the experimental group, the three-piece maxillary dental arch was articulated again automatically from the patient's original occlusion using the mathematical algorithm. The hand- and algorithm-articulated occlusions were then evaluated qualitatively by two experienced orthodontists. A quantitative evaluation was also performed. The results of the qualitative evaluation showed that all of the three-piece occlusions, hand- and algorithm-articulated, were clinically acceptable based on the American Board of Orthodontics grading system. When compared, two of the algorithm-articulated occlusions were clearly better (40%), one was the same (20%), and two were slightly worse (40%) than the hand-articulated occlusions. All of the quantitative measurements were comparable between the two articulation methods. In conclusion, the results of this study demonstrate that it is clinically feasible to digitally articulate the three-piece maxillary arch to the intact mandibular dental arch. [ABSTRACT FROM AUTHOR]

Copyright of Giornale Italiano di Medicina del Lavoro ed Ergonomia is the property of Giornale Italiano di Medicina del Lavoro ed Ergonomia Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Suboptimal quality of feasibility assessments might partially explain inconsistencies observed in the effectiveness of exercise prehabilitation before colorectal cancer (CRC) surgery. This systematic review aimed to assess the reporting quality and clinical generalizability of feasibility outcomes in feasibility studies addressing exercise prehabilitation before CRC surgery. PubMed/Medline, Embase, Cochrane, and CINAHL were searched to identify all feasibility studies focussing on exercise prehabilitation in CRC surgery. Reporting quality was assessed using the Thabane et al. checklist and the Consolidated Standards of Reporting Trials extension for feasibility studies. Clinical generalizability was evaluated by appraising patient participation in all steps of the study and intervention. Twelve studies were included. The main feasibility outcome in all studies was adherence to the intervention by the study sample. Based on adherence, 10 studies (83%) concluded exercise prehabilitation to be feasible. Six studies (50%) reported all details to assess patient participation showing retention rates between 18.4% and 58.2%, which was caused by non-participation and drop-out. Three feasibility studies (25%) discussed patient-reported barriers to participation and five additional studies (41%) described potential selection bias. Four studies (33%) reported lessons learned to solve issues hampering feasibility and clinical generalizability. Results suggest that true feasibility of exercise prehabilitation before CRC surgery remains questionable due to poor reporting quality, insufficient clarity regarding the representativeness of the study sample for the target population, and limited attention for clinical generalizability. Feasibility of exercise prehabilitation might be improved by offering supervised community- or home-based interventions tailored to the physical and mental abilities of the patient. • Feasibility of exercise prehabilitation before colorectal cancer surgery remains questionable • Feasibility studies insufficiently report feasibility for patients to participate • It is often unclear if study populations adequately represent the entire target populations • Feasibility studies should focus explicitly on external validity of the results • Patient-reported barriers to participation should be considered [ABSTRACT FROM AUTHOR]

A financial feasibility study has been identified as a 'critical success factor' of construction projects that can cause these projects to fail, if not executed or communicated correctly. Yet, research indicates that the aforementioned feasibilities are not executed well, inconsistent, neglected, and problematic. They greatly lack best practice items. An audience analysis was conducted through semi-structured interviews with 23 real estate developers in the private sector. This analysis presented the developers' needs and requirements for the documents. A total of 23 requirements were identified. From these requirements, an evaluation tool was created and 18 financial feasibility studies were evaluated. The average score of all 18 feasibilities is 62%. Three feasibilities achieved a below-average score in both categories. Six (33.33%) of the feasibilities managed to score above average in both categories, while the average of the respective categories are 68% and 50%. The data indicates that an audience analyses lacks in the industry, leading to poor communication that does not fulfil the needs of real estate developers. [ABSTRACT FROM AUTHOR]

Objectives: This study aimed to examine the usability, feasibility, acceptability, and appropriateness of the information and communication technology for emergency medical services (ICT-EMS) systems to improve the transportation of emergency patients during the COVID-19 pandemic.Methods: Emergency medical technicians (EMTs) (n = 229) employed at 7 fire stations operated by the North Chungcheong Fire Service Headquarters, South Korea were trained to use ICT-EMS devices prior to a 1-month implementation period. System Usability Scale (SUS), Feasibility of Intervention Measure (FIM), Acceptability of Intervention Measure (AIM), and Intervention Appropriateness Measure (IAM) questionnaires were conducted in the 4th week of the 1-month implementation period to assess the perceived usability, feasibility, acceptability, and appropriateness of the ICT-EMS systems.Results: Among a total of 229 EMTs, 187 EMTs (81.7%) completed the survey. The overall SUS score was significantly low (score of 35.6) indicating an overall negative perception of the ICT-EMS systems. With regard to the feasibility, acceptability, and intervention appropriateness of ICT-EMS, roughly 50 (26.7%) participants agreed that ICT-EMS implementation was possible, appealing, and suitable.Conclusion: Many potential areas of improvement were identified within the ICT-EMS systems. System alterations regarding usability, feasibility, acceptability, and appropriateness may be necessary to successfully implement the ICT-EMS systems. [ABSTRACT FROM AUTHOR]

Transportation systems are somewhat incomplete without integrating non-motorised transport (NMT) facilities to ensure safety, security, convenience, productivity and reduced environmental impact from such projects. This study examined the performance of NMT infrastructure and services provided to ensure smart transport and mobility in Johannesburg, South Africa. Two projects were identified as case studies, and a total of 21 semi-structured, open-ended interviews were conducted with residents and other road users in the vicinity of the projects to enable the acquisition of relevant information. Data was analysed using thematic content analysis supported with Atlas-ti software. Findings revealed that, although the facilities are in good condition and adequately maintained, the usage level is low. Incidents of poor safety and security were reported. Nevertheless, new value-added businesses operate along the routes and users indicated some satisfaction with their travel experience. To achieve value creation where NMTs are provided, it is crucial to ensure that the “smartness” of the cities is achieved and sustained. The practical implication of this study is the provision of invaluable information towards assisting road and NMT infrastructure stakeholders in improving the planning and delivery of sustainable transport infrastructure. Future studies will benefit from using more case study projects to strengthen these findings further and improve the generalisability. [ABSTRACT FROM AUTHOR]

Objectives: We examined the feasibility (i.e. single-session attendance) of conducting 3 counselor-delivered nonpharmacological pain management intervention (NPMI) groups in methadone maintenance treatment (MMT): (1) Coping with Pain , an intervention based on cognitive-behavioral therapy, (2) Wii-Covery, an exergame intervention to facilitate exercise, and (3) Juggling Group , an intervention to promote social inclusion and reduce stress. We examined pre-post session changes in pain and mood associated with group attendance. Methods: Over 1 month at an MMT clinic with 1800 patients, each NPMI group was offered daily Monday-Friday and 1 was offered on Saturdays. A standardized but unvalidated measure was administered before and after sessions to assess acute changes in current pain intensity and mood states. Paired t -tests with Bonferroni corrections were performed for each NPMI group (P < 0.0007 [.05/7]). Results: About 452 patients (67% male, 84% White, mean age, 40) attended at least 1 NPMI group. About 57% reported current chronic pain. Attendance at any NPMI group (for the whole sample and the subset with chronic pain) was significantly associated with acute reductions in current pain intensity, anxiety, depression, and stress, and acute increases in current energy and happiness. Attendance at Coping with Pain and Juggling Group was also associated with acute increases in compassion. Conclusions: Coping with Pain, Wii-Covery, and Juggling Group are feasible to conduct in MMT, and acute improvements in current pain intensity and specific mood states associated with a single session attendance point to the importance of examining systematically the efficacy of these and other NPMIs in MMT. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate in vitro the potential of an intraoral scanner (IOS) to monitor erosive tooth wear (ETW) using different alignment software with distinct quantitative measurement metrics. Methods: 15 unpolished bovine crowns were exposed to citric acid (pH ~2.5) at 24-hour intervals up to 168 hours. At baseline and after each acid exposure episode, the teeth were scanned with IOS (3Shape TRIOS 3). Scanned images from each data point were superimposed on baseline image using WearCompare software to obtain volume loss (mm³) and area loss (mm²) and using IOS built-in software (3Shape TRIOS Patient Monitoring) to obtain depth loss (mm). Pearson's test was used to determine the correlation between acid exposure time (h) and each outcome measure (a= 0.05). Results: As the acid exposure time increased, the lesion parameters (depth, volume, and area) increased. Friedman's test showed that relative to baseline volume loss became significant (P< 0.05) after 72 hours from median 11.48 mm³ (IQI 25% = 8.72 mm³), eroded area became significant (P< 0.05) from median 48.67 mm² (IQI 25% = 44.46 mm², P< 0.05) after 96 hours, and erosion depth became significant (P< 0.05) from median 0.69 mm (IQI 25% = 0.66 mm²) after 144 hours. A strong correlation was observed between depth (mm²) and time (r= 0.9993 P< 0.0001), volume (mm³) and time (r= 0.9968, P< 0.0001), and area (mm²) and time (r= 0.9475, P= 0.0003). [ABSTRACT FROM AUTHOR]

• Spiral MRI sequences can be implemented on a standard clinical MRI scanner. • Spiral MRI offers high k-space sampling efficiency and artifact robustness. • The spiral acquisition window is an important scan parameter. • Spiral 3D TOF MRA sequences can be used for rapid non-contrast carotid artery imaging. To assess the clinical feasibility of spiral 3D Time-Of-Flight (TOF) MR Angiography (MRA) sequence variants for rapid non-contrast carotid artery imaging. Nine different 3D TOF MRA sequences were acquired in nine healthy volunteers on a standard clinical 1.5 T scanner. Three cartesian sequences (fully sampled (10:15 min), accelerated with SENSE (05:08 min), accelerated with Compressed SENSE (03:32 min)) and six different spiral sequences were acquired (spiral acquisition windows ranging from 10 to 5 ms (01:32 min-03:05 min)). Three readers graded the images qualitatively in terms of overall image quality, vessel sharpness, inhomogeneous intraluminal signal, background noise, visualization of large and small vessels and overall impression of the number of visible vessels. Cross-sectional areas of the vessel lumen were measured and vessel sharpness was quantified. The SENSE and Compressed SENSE accelerated cartesian sequences and the Spiral 6 ms and 5 ms sequences were deemed comparable to the fully sampled cartesian sequence in most qualitative categories (p > 0.05) based on exact binomial tests. The Spiral 6 ms and 5 ms sequences achieved a scan time reduction of 75.3% and 69.9% respectively compared to the fully sampled cartesian sequence. The spiral sequences (generally) exhibited improved subjective vessel sharpness (p < 0.01-p = 0.13) but increased background noise (p = 0.03-p = 0.25). Cross-sectional area measurements were similar between all sequences (Krippendorff's alpha: 0.955–0.982). Quantitative vessel sharpness was increased for all spiral sequences compared to all cartesian sequences (p = 0.004). Spiral 3D TOF MRA sequences with a spiral acquisition window of 5 ms or 6 ms may be used for accurate, rapid, clinical non-contrast carotid artery imaging. [ABSTRACT FROM AUTHOR]

A major challenge in the process of innovation is to generate quality products that are original as well as feasible, because these features are associated with contradictory cognitive thought processes. This study investigated whether opportunities to engage in an idea generation, selection, and subsequent refinement with a simultaneous focus on originality and feasibility would enhance innovation. Experiment 1 examined whether a linear focus or a simultaneous focus on feasibility and originality in the process of first generating ideas and then refining them enhanced the overall quality of ideas. The simultaneous focus resulted in the highest originality and elaboration of ideas. Experiment 2 involved four stages of innovation—generation, selection, and two refinement phases—with a varied order of focus in the two refinement phases. Consistent with a dialectical approach to creativity, an iterative focus on feasibility and originality in the refinement phase was most beneficial in enhancing the quality of the ideas. The extent of idea elaboration played a mediation role in the development of ideas during the refinement phase of innovation. [ABSTRACT FROM AUTHOR]