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On the basis of a new regional dust model system, the sensitivity of radiative forcing to dust aerosol properties and the impact on atmospheric dynamics were investigated. Uncertainties in optical properties were related to uncertainties in the complex spectral refractive index of mineral dust. The climatological‐based distribution of desert‐type aerosol in the radiation scheme of the nonhydrostatic regional model LM was replaced by dust optical properties from spectral refractive indices, derived from in situ measurements, remote sensing, bulk measurements, and laboratory experiments, employing Mie theory. The model computes changes in the solar and terrestrial irradiance from a spatially and temporally varying atmospheric dust load for five size classes. A model study of a Saharan dust outbreak in October 2001 was carried out when large amounts of Saharan dust were transported to Europe. The dust optical thickness computed from the simulation results in values of about 0.5 in large regions of the Saharan desert but can be larger than 5.0 near large dust sources (for example, Bodélé depression). During the dust outbreak, the aerosol in the southern Sahara causes a daytime reduction in 2‐m temperature of 3 K in average with differences of 10% depending on used dust optical properties. The simulations indicated that the large variability in radiative properties due to different mixture of clay aggregates in Saharan dust can lead in regional average to differences of up to 48% in net forcing efficiency at top of the atmosphere.