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Drug craving has been defined as tendency or compulsion to abuse substances. Coping skills approach provides a systematic way assessing the full range of antecedents' and consequences of abusing drug that influence an individual's craving potential and devising interventions to deal with them that are likely to reduce the probability of future relapse. Aim to enhancing coping skills to reduce drug craving among addicts. Study design: a quasiexperimental design was utilized to conduct this study. Setting: this study was conducted in the Heliopolis psychiatric Hospital. Subject: convenient sample of thirty patients suffered from drug craving at the addiction outpatient clinic, Data collection tools: 1) Socio-demographic interview questionnaire to assess the socio demographic characteristics of study subjects and data related to the previous history of drug abuse and relapse. 2) Drug craving questionnaire that was used to assess variable contributing to craving among drug abuse. 3) Coping Behavior Inventory (CBI) that was used to assess coping skills among drug craving patients. Results: The present study revealed that youth aged between twenty-five to thirty-five years were the most prone to multiple craving factors, the intervention program was successful in improving coping skills with high risk factors of craving. Conclusion: improvement of behavioral and cognitive coping skills with high-risk situation after program implementation. Recommendations: designing continuous health education programs for family caregivers and their patients with craving to teach them how to avoid craving and how to enhance their coping skills. Psychiatric /mental health nurses should have active role in helping patients with drug craving to cope effectively with high risk factors of craving [ABSTRACT FROM AUTHOR]

Purpose: The prognostic value of [18F]-fluorodeoxyglucose positron emission tomography (FDG PET) in early-stage high-risk cervical cancer patients was evaluated. Materials and Methods:A total of 86 Stage IB or IIA cervical cancer patients with high risk factors (positive resection margin (RM), parametrial invasion (PI) or pelvic lymph node (PLN) metastasis) were retrospectively investigated. Results: There was a statistically significant decrease in recurrence-free survival (RFS) in patients with bulky tumor (p = 0.011), positive RM (p = 0.001), and PLN positivity on FDG PET (p = 0.012) in multivariate analyses. Independent prognostic factors for overall survival (OS) included non-squamous cell type (p = 0.005), bulky tumor (p = 0.020), and PLN positivity on FDG PET (p = 0.007). Patients with positive PLN on FDG PET had worse five-year RFS (62.0% vs. 85.0%, p = 0.013) and OS (68.7% vs. 89.5%, p = 0.011) rates than those with negative PLN uptake. Conclusion: PLN metastasis on FDG PET and bulky tumor were found to be statistically significant prognostic factors for both RFS and OS in early-stage high-risk cervical cancer patients. [ABSTRACT FROM AUTHOR]

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Venous thromboembolism (VTE) is a life-threatening complication that often occurs in ovarian tumors. However, the risk factors for VTE are still undetermined.We retrospectively analyzed VTE occurrence and its potential risk factors in 254 Chinese patients with ovarian tumor at Fudan University Cancer Hospital from July 2007 to June 2011.The VTE incidence was 7.1% (13/183) in epithelial ovarian cancer (EOC), and no VTE was found in ovarian borderline or benign tumor. D-dimer levels were significantly higher in EOC than in ovarian benign and borderline tumors. Furthermore, D-dimer levels increased with the advancement of EOC stages. Correlation analysis suggested that D-dimer levels were well correlated with platelet counting (PLT), prothrombin time (PT), white blood cell counting (WBC), cancer antigen (CA) 125, and CA153. Univariate logistic regression analysis found that D-dimer levels greater than 788 μg/L, PLT levels greater than 261 × 109/L, PT greater than 11.7 seconds, CA125 greater than 760 U/mL, and ascites greater than 1500 mL are risk factors for VTE in EOC. Moreover, multivariate analysis grouped primary EOC, low differentiated grade, D-dimer greater than 788 μg/L, PT greater than 11.7 seconds, and CA125 greater than 760 U/mL as prediction factors for VTE.In addition to D-dimer and ascites, high levels of PLT, PT, and CA125, which are highly correlated with D-dimer, are independent risk factors for VTE [ABSTRACT FROM AUTHOR]