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The gas lift method is an artificial lift method of well production using the energy of compressed gas injected into the well to lift the reservoir fluid to the surface. The formation of paraffin deposits has remained one of the critical oil production problems due to the growing percentage of hard-to-recover reserves in the overall structure. This complication is also typical for many oil and gas fields in Vietnam, such as the White Tiger, White Bear, and Dragon fields. Wax deposit formation negatively affects the operation of individual production wells and the development of the field as a whole, which leads to a decrease in productivity and the need to take measures to remove paraffin deposits, subsequently increasing the downtime period of the well. In order to ensure stable production of highly paraffinic oil, it is necessary to take measures to dewax wells systematically. The frequency of wax removal operations depends on the intensity of the wax formation, which is determined by various technological, technical, and geological factors. The interval between dewaxing operations is called the dewaxing interval period (DIP). This value is an important technological parameter and characterizes the efficiency of a well’s operation. In this study, a comprehensive method has been developed to determine the dewaxing interval period (treatment interval) for gas-lift wells when the formation of wax deposits has occurred. The optimal dewaxing interval period is suggested to be determined by the change in the liquid well flow rate at the point when it falls by 20% from the initial value. In addition, a mathematical model of the time-dependent wax thickness, taking into account the heat and mass transfer laws and the laboratory results using the Cold Finger method, has also been developed. The proposed model for determining the dewaxing interval period was applied to an oil well in Vietnam. The DIP prediction model gave a similar value to the actual DIP field data (6.67 and 6 days, respectively). The obtained results showed that the model had proven its accuracy following the results of a comparison with the field's data of dewaxing operations.