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Background: The population of Aging cancer survivors in the United States has surged to over 16.9 million. Research on the relationship between statin usage and post-cancer survival rates remains limited. Aims: This study aims to investigate the association between statin use and various causes of mortality among aging cancer survivors. Methods: We analyzed NHANES data from 1999 to 2018, Statin usage, both hydrophilic and lipophilic, was derived from NHANES prescription records. We utilized Cox proportional hazards models to associate statin utilization with mortality, differentiating causes of death according to statin type and patterns of use. Results: Within a cohort of 2,968 participants, statin usage was categorized into non-users (1,738), hydrophilic statin users (216), and lipophilic statin users (982). Compared to those who did not use statins, individuals prescribed hydrophilic statins did not show a reduced risk of all-cause mortality (adjusted hazard ratio [HR] 1.01; 95% confidence interval [CI] 0.72–1.41; P = 0.960), as outlined in Model 3. In contrast, the group receiving lipophilic statins exhibited a notable decrease in all-cause mortality risk (adjusted HR, 0.77; P = 0.003). Nonetheless, both hydrophilic and lipophilic statins were effective in diminishing the risk associated with cancer from its onset until death, with hydrophilic statins showing a greater level of efficacy. Discussion: The potential of statins to reduce cancer-related mortality may provide avenues for targeted clinical interventions and management strategies. Conclusions: Our study reveals that the use of lipophilic statins is significantly associated with lower all-cause and cancer-cause mortality risks among aging cancer survivors. [ABSTRACT FROM AUTHOR]

Though Timothy Richard is a Christian missionary to China,his response to Mahayana Buddhism aims at neither the conversion of the Chinese Buddhists to Christianity nor the justification of Western colonialism. On the contrary, he aims at building up the friendship and cooperation between Christians and Buddhists in the fight against militarism and the establishment of world peace and justice. Unlike many of his contemporaries, Richard regarded Mahayana Buddhism as a higher Buddhism rather than a distortion of Buddhism. Instead of highlighting the superiority of the West through stereotyping the contrast between the East and the West,Richard emphasized the similarities and historical interactions between Christianity and Mahayana Buddhism. Richard's response to Mahayana Buddhism can be said to be a counter-example challenging the theory of Orientalism articulated by Edward Said. [ABSTRACT FROM AUTHOR]

The article presents a profile of the life and work of the Chinese Christian intellectual Xie Fuya, also known as N. Z. Zia. Particular attention is paid to re-evaluating the significance of Xie's work and the criticism directed toward him in the context of fellow diasporic Chinese intellectuals who left China after the outbreak of civil war in 1949. The suggestion that Xie shifted his interest from promoting the "indigenous Church" to "indigenous theology" by combining Christian faith and Confucian thought is analyzed. Xie's political concerns and social participation while in exile in Hong Kong and Taiwan are examined. Criticisms over the feasibility of a Chinese Christian theology as proposed by Xie are assessed.

Background: The long-term effects of botulinum toxin type A (BoNTA) on the global impairment associated with severe primary axillary hyperhidrosis have not been comprehensively assessed relative to placebo. Objective: To assess the efficacy and safety of 2 dosages of BoNTA compared with placebo in subjects with primary axillary hyperhidrosis. Methods: Subjects (N = 322) were randomized to the use of BoNTA (75 U or 50 U/axilla) or placebo in this 52-week, multicenter, double-blind study. Results: BoNTA treatment significantly reduced daily activity limitations at 4 weeks after injection. A 2-point improvement on the 4-point Hyperhidrosis Disease Severity Scale (HDSS) was reported in 75% of subjects in the 75-U and 50-U BoNTA groups and in 25% of the placebo group (P < .001). Improvements in HDSS scores were corroborated by gravimetric results. The median duration of effect was 197 days, 205 days, and 96 days in the 75-U, 50-U, and placebo groups, respectively. BoNTA was well tolerated. Limitations: The effect of total surface area involvement on treatment efficacy was not evaluated. Conclusion: BoNTA treatment effectively reduces the symptoms of primary axillary hyperhidrosis and is well tolerated. [Copyright &y& Elsevier]

The impact of transgenic crops on non-target organisms is a key aspect of environmental safety assessment to transgenic crops. In the present study, we fed two snail species, Bradybaena (Acusta) ravida (B. ravida) and Bradybaena similaris (Ferussac)(B. similaris) , with the leaves of transgenic Bt cotton Zhong 30 (Z30) and control cotton, its parent line zhong 16 (Z16), to assess the environmental safety of Bt cotton to common non-target organisms in the field. Survival, body weight, shell diameter, helix number, reproduction rate, superoxide dismutase (SOD) activity and Bt protein concentration in snails were monitored in 15 days and 180 days experiments. We also monitored the population dynamics of B. ravida and B. similaris in Z30 and Z16 cotton fields for two successive years. Compared to the snails fed on the control cotton Z16, there was no significant difference in survival, growth, reproduction, and SOD activity on Bt cotton Z30. Bt protein concentrations were significantly between different treatments, and Bt protein residues were only detected in the feces of the Z30 treatment. According to the field data, the number of B. ravida and B. similaris fluctuated considerably across seasons over the entire cotton-growing season; however, there were no significant differences between the Bt and control cotton fields at similar time. As the results showed, in our experiments, Bt cotton Z30 had no adverse effects on the two snail species, both in the laboratory and in the fields. • The effects of Bt cotton Z30 on two land snail species (B. ravida and B. similaris) were studied for the first time. • Our research includinged short-term and long-term toxicological experiments in lab and field investigation. • We set up a good platform was established to evaluate the effect of transgenic plants on land snails in the future. • We found that the helix number is more stable and reliable than body weight and diameter, which was rarely used before. [ABSTRACT FROM AUTHOR]