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AbstractBackgroundThis manuscript presents evidence-based guidance on the use of 38% silver diamine fluoride (SDF) for dental caries management in children and adolescents, including those with special health care needs. A guideline workgroup formed by the American Academy of Pediatric Dentistry developed guidance and an evidence-based recommendation regarding the application of 38% SDF to arrest cavitated caries lesions in primary teeth.Types of studies reviewedThe basis of the guideline’s recommendation is evidence from an existing systematic review “Clinical trials of silver diamine fluoride in arresting caries among children: A systematic review.” (JDR Clin Transl Res2016;1[3]:201–10). A systematic search was conducted in PubMed/MEDLINE, Embase, Cochrane Central Register of Controlled Trials and gray literature databases to identify randomized controlled trials and systematic reviews reporting on the effect of silver diamine fluoride and address peripheral issues such as adverse effects and cost. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess the quality of the evidence and the evidence-to-decision framework was employed to formulate a recommendation.ResultsThe panel made a conditional recommendation regarding the use of 38% SDF for the arrest of cavitated caries lesions in primary teeth as part of a comprehensive caries management program. After taking into consideration the low cost of the treatment and the disease burden of caries, panel members were confident that the benefits of SDF application in the target populations outweigh its possible undesirable effects. Per GRADE, this is a conditional recommendation based on low-quality evidence.Conclusions and practical implicationsThe guideline intends to inform the clinical practices involving the application of 38% SDF to enhance dental caries management outcomes in children and adolescents, including those with special health care needs. These recommended practices are based upon the best available evidence to-date. A 38% SDF protocol is included in Appendix II (Pediatr Dent2017;39(5):E135–E145).

The authors conducted a systematic review and meta-analysis to compare the long-term clinical and radiographic success of using mineral trioxide aggregate (MTA) and formocresol (FC) as a pulp-dressing material in pulpotomy treatment in primary molars.

A critical summary of Lodi G, Figini L, Sardella A, Carrassi A, Del Fabbro M, Furness S. Antibiotics to prevent complications following tooth extractions. Cochrane Database Syst Rev 2012;11:CD003811. doi:10.1002/14651858.CD003811.pub2.

A critical summary of Lodi G, Figini L, Sardella A, Carrassi A, Del Fabbro M, Furness S. Antibiotics to prevent complications following tooth extractions. Cochrane Database Syst Rev 2012;11:CD003811. doi:10.1002/14651858.CD003811.pub2.