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The rotational velocity of distant galaxies, when interpreted as a size (luminosity) indicator, may be used as a tool to select high redshift standard rods (candles) and probe world models and galaxy evolution via the classical angular diameter-redshift or Hubble diagram tests. We implement the proposed testing strategy using a sample of 30 rotators spanning the redshift range 0.2 < z < 1 with high resolution spectra and images obtained by the VIMOS/VLT Deep Redshift Survey (VVDS) and the Great Observatories Origins Deep Survey (GOODs). We show that by applying at the same time the angular diameter-redshift and Hubble diagrams to the same sample of objects (i.e. velocity selected galactic discs) one can derive a characteristic chart, the cosmology-evolution diagram, mapping the relation between global cosmological parameters and local structural parameters of discs such as size and luminosity. This chart allows to put constraints on cosmological parameters when general prior information about discs evolution is available. In particular, by assuming that equally rotating large discs cannot be less luminous at z = 1 than at present (M(z=1) ?M(0)), we find that a flat matter dominated cosmology (?m=1) is excluded at a confidence level of 2 ? and an open cosmology with low mass density (?m?0.3) and no dark energy contribution (??) is excluded at a confidence level greater than 1 ?. Inversely, by assuming prior knowledge about the cosmological model, the cosmology-evolution diagram can be used to gain useful insights about the redshift evolution of baryonic discs hosted in dark matter halos of nearly equal masses. In particular, in a ?CDM cosmology, we find evidence for a bimodal evolution where the low-mass discs have undergone significant surface brightness evolution over the last 8.5 Gyr, while more massive systems have not. We suggest that this dichotomy can be explained by the epochs at which these two different populations last assembled.??

This is the second in a series of three papers dedicated to a new technique to select galaxies that can act as standard rods and standard candles in order to perform geometrical tests on large samples of high redshift galaxies to constrain different cosmological parameters. The goals of this paper are (1) to compare different rotation indicators in order to understand the relation between rotation velocities extracted from observations of the H??6563???line and the [OII]?3727???line; and (2) to determine the scaling relations between physical size, surface brightness and magnitude of disc galaxies and their rotation velocity using the SFI++, a large catalog of nearby galaxies observed at I-band. A good correlation is observed between the rotation curve-derived velocities of the H? and [OII] observations, as well as between those calculated from velocity histograms, justifying the direct comparison of velocities measured from H? rotation curves in nearby galaxies and from [OII] line widths at higher redshifts. To provide calibration for the geometrical tests, we give expressions for the different scaling relations between properties of galaxies (size, surface brightness, magnitude) and their rotation speeds. We use Malmquist bias-corrected distances from the SFI++ template Tully-Fisher relation to generate a size-rotation velocity relation with unprecedentedly small scatter. We show how the best size-rotation velocity relation is derived when size is estimated not from disc scale lengths but from the isophotal diameter r23.5, once these have been corrected for inclination and extinction effects.

We suggest to use the observationally measured and theoretically justified correlation between size and rotational velocity of galactic discs as a viable method to select a set of high redshift standard rods which may be used to explore the dark energy content of the universe via the classical angular-diameter test. Here we explore a new strategy for an optimal implementation of this test. We propose to use the rotation speed of high redshift galaxies as a standard size indicator and show how high resolution multi-object spectroscopy and ACS/HST high quality spatial images, may be combined to measure the amplitude of the dark energy density parameter ?Q, or to constrain the cosmic equation of state parameter for a smooth dark energy component (w = p/?, -1 ? w < -1/3). Nearly 1300?standard rods with high velocity rotation in the bin V = 200 ? 20?km?s-1are expected in a field of 1 sq. degree and over the redshift baseline 0 < z < 1.4. This sample is sufficient to constrain the cosmic equation of state parameter w at a level of 20% (without priors in the [?m,?Q] plane) even when the [OII]?3727??? linewidth-diameter relationship is calibrated with a scatter of ~40%. We evaluate how systematics may affect the proposed tests, and find that a linear standard rod evolution, causing galaxy dimensions to be up to?30% smaller at z = 1.5, can be uniquely diagnosed, and will minimally bias the confidence level contours in the [ ?Q, w] plane. Finally, we show how to derive, without a?priori knowing the specific functional form of disc evolution, a cosmology-evolution diagram with which it is possible to establish a mapping between different cosmological models and the amount of galaxy disc/luminosity evolution expected at a given redshift.?

The attachment of antibodies to substrate surfaces is useful for achieving specific detection of antigens and toxins associated with clinical and field diagnostics. Here, acrylated whole antibodies were produced through conjugation chemistry, with the goal of covalently photografting these proteins from surfaces in a controlled fashion, to facilitate rapid and sensitive antigenic detection. A living radical photopolymerization chemistry was used to graft the acrylated whole antibodies on polymer surfaces at controlled densities and spatial locations by controlling the exposure time and area, respectively. Copolymer grafts containing these antibodies were synthesized to demonstrate two principles. First, PEG functionalities were introduced to prevent nonspecific protein interactions and improve the reaction kinetics by increasing solvation and mobility of the antibody-containing chains. Both of these properties lead to sensitive (pM) and rapid (&lt;20 min) detection of antigens with this surface modification technique. Second, graft composition was tailored to include multiple antibodies on the same grafted chains, establishing a means for simultaneously detecting multiple antigens on one grafted surface area. Finally, the addition of PEG spacers between the acrylate functionality and the pendant detection antibodies was tuned to enhance the detection of a short-half-life molecule, glucagon, in a complex biological environment, plasma.