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In this paper a new sensor interface using current mode approach is presented for biomedical applications. The proposed sensor interface utilises a low-power current-mode comparator, an 8 bit current mode successive approximation analogue to digital converter (SA-ADC), an adaptable band-pass filter as well as a highly linear transconductance amplifier (Gm). The Gm and current mode SAR ADC are designed in a way to achieve minimum power consumption. The circuit is simulated in 0.18 μm CMOS technology with supply voltage of 1.8 V. At 400 KS/s sampling frequency, the total power consumption and total harmonic distortion of the system are obtained equal to 2.2 μW and 45.2 dB respectively. The simulation results demonstrate the effectiveness and superiority of the proposed circuit in comparison with the conventional circuits.